On page 1 showing 1 ~ 20 out of 55 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: CD-1
Assessments: Elevated plus maze test, Histology, Novel object recognition test, Open field test, T-Maze, Western blot, infarct volume
Citation: Farr SA, Cuzzocrea S, Esposito E, Campolo M, Niehoff ML, Doyle TM, Salvemini D. Adenosine A(3) receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injuryJ Neuroinflammation. 2020 Nov 12;17(1):339. doi: 10.1186\/s12974-020-02009-7. PMC7659122
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Histology, Neurological Severity Score (NSS), RT-PCR
Citation: Songarj P, Luh C, Staib-Lasarzik I, Engelhard K, Moosmann B, Thal SC. The antioxidative, non-psychoactive tricyclic phenothiazine reduces brain damage after experimental traumatic brain injury in miceNeurosci Lett. 2015 Jan 1;584:253-8. doi: 10.1016\\/j.neulet.2014.10.037. Epub 2014 Oct 28.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Albino
Assessments: Histology, Lowry method, Tissue Caspase-3, Tissue Glutathione Peroxidase, Tissue Malondialdehyde, Tissue Superoxide Dismutase
Citation: Özay R, Türkoğlu E, Gürer B, Dolgun H, Evirgen O, Ergüder Bİ, Hayırlı N, Gürses L, Şekerci Z, Yılmaz ER. Does Decorin Protect Neuronal Tissue via Its Antioxidant and Antiinflammatory Activity from Traumatic Brain Injury? An Experimental StudyWorld Neurosurg. 2017 Jan;97:407-415. doi: 10.1016\/j.wneu.2016.09.115. Epub 2016 Oct 12.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Albino
Assessments: Histology, Lowry method, Tissue Caspase-3 Analysis, Tissue Glutathione Peroxidase Analysis, Tissue Malondialdehyde Analysis, Tissue Nitric Oxide Analysis, Tissue Superoxide Dismutase Analysis
Citation: Özay R, Türkoğlu ME, Gürer B, Dolgun H, Evirgen O, Ergüder Bİ, Hayırlı N, Gürses L, Şekerci Z. The Protective Effect of Omeprazole Against Traumatic Brain Injury: An Experimental StudyWorld Neurosurg. 2017 Aug;104:634-643. doi: 10.1016\/j.wneu.2017.04.136. Epub 2017 Apr 28.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Morris Water Maze (MWM)
Citation: Adelson PD, Fellows-Mayle W, Kochanek PM, Dixon CE. Morris water maze function and histologic characterization of two age-at-injury experimental models of controlled cortical impact in the immature ratChilds Nerv Syst. 2013 Jan;29(1):43-53. doi: 10.1007\/s00381-012-1932-4. Epub 2012 Oct 23.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Image analysis, Morris Water Maze (MWM)
Citation: Barot J, Saxena B. Therapeutic effects of eugenol in a rat model of traumatic brain injury: A behavioral, biochemical, and histological studyJ Tradit Complement Med. 2021 Jan 8;11(4):318-327. doi: 10.1016\/j.jtcme.2021.01.003. eCollection 2021 Jul. PMC8240337
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Histology, Morris Water Maze (MWM)
Citation: Smith DH, Soares HD, Pierce JS, Perlman KG, Saatman KE, Meaney DF, Dixon CE, McIntosh TK. A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effectsJ Neurotrauma. 1995 Apr;12(2):169-78. doi: 10.1089\/neu.1995.12.169.
TBI Model Type: Controlled cortical impact model
Organism Species: pig
Organism Strain: Yorkshire
Assessments: Histology
Citation: Sindelar B, Bailes J, Sherman S, Finan J, Stone J, Lee J, Ahmadian S, Zhou Y, Patel V, Smith D. Effect of Internal Jugular Vein Compression on Intracranial Hemorrhage in a Porcine Controlled Cortical Impact ModelJ Neurotrauma. 2017 Apr 15;34(8):1703-1709. doi: 10.1089\/neu.2016.4648. Epub 2016 Dec 16.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Blood–brain barrier permeability, glutathione levels, Histology, malondialdehyde (MDA)
Citation: Özevren H, Deveci E, Tuncer MC. Histopathological changes in the choroid plexus after traumatic brain injury in the rats: a histologic and immunohistochemical studyFolia Morphol (Warsz). 2018;77(4):642-648. doi: 10.5603\/FM.a2018.0029. Epub 2018 Mar 23.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6-SJLF1
Assessments: Conditioned fear testing, Morris Water Maze (MWM), Rotorod test, Histology, shock sensitivity testing
Citation: Brody DL, Mac Donald C, Kessens CC, Yuede C, Parsadanian M, Spinner M, Kim E, Schwetye KE, Holtzman DM, Bayly PV. Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injuryJ Neurotrauma. 2007 Apr;24(4):657-73. doi: 10.1089\/neu.2006.0011. PMC2435168
TBI Model Type: Controlled cortical impact model
Organism Species: pig
Organism Strain: No strain reported
Assessments: Histology, Immunohistochemistry (IHC), microdialysis
Citation: Kilbaugh TJ, Bhandare S, Lorom DH, Saraswati M, Robertson CL, Margulies SS. Cyclosporin A preserves mitochondrial function after traumatic brain injury in the immature rat and pigletJ Neurotrauma. 2011 May;28(5):763-74. doi: 10.1089\/neu.2010.1635. Epub 2011 Apr 12. PMC3125546
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: modified Neurological Severity Score (mNSS), Neurological examination, Sensorimotor examination, Nissl staining, light/dark anxiety transition test, conditioned passive avoidance response, elevated plus-maze, histology, Hematoxylin and Eosin
Citation: Plekhova NG, Radkov IV, Zinoviev SV, Dyuizen IV, Baryshev AN, Shumatov VB. Effect of Mild Traumatic Brain Injury on Behavioral Reactions and Neocortical Morphology in RatsBull Exp Biol Med. 2021 Mar;170(5):672-676. doi: 10.1007\/s10517-021-05130-6. Epub 2021 Mar 31.
TBI Model Type: Other
Organism Species: mouse
Organism Strain: C57Bl/6
Assessments: Barnes Maze test, Enzyme-Linked Immunosorbent Assay (ELISA), Histology, LRR, Neurological Severity Score (NSS), open field test, Silver staining, Western blot, Rotarod test, passive avoidance task, thigmotaxis index
Citation: Namjoshi DR, Cheng WH, McInnes KA, Martens KM, Carr M, Wilkinson A, Fan J, Robert J, Hayat A, Cripton PA, Wellington CL. Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injuryMol Neurodegener. 2014 Dec 1;9:55. doi: 10.1186\/1750-1326-9-55. PMC4269957
TBI Model Type: Other
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Fluoro-Jade B staining (FJB), Histology, Locomotor behavior, Immunohistochemistry (IHC)
Citation: Turner RC, Naser ZJ, Lucke-Wold BP, Logsdon AF, Vangilder RL, Matsumoto RR, Huber JD, Rosen CL. Single low-dose lipopolysaccharide preconditioning: neuroprotective against axonal injury and modulates glial cellsNeuroimmunol Neuroinflamm. 2017 Jan;4:6-15. doi: 10.20517\/2347-8659.2016.40. Epub 2017 Jan 20. PMC5289820
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Immunohistochemitry, Western blot, error ladder walking test, Novel object recognition test
Citation: Chen H, Chan YL, Nguyen LT, Mao Y, de Rosa A, Beh IT, Chee C, Oliver B, Herok G, Saad S, Gorrie C. Moderate traumatic brain injury is linked to acute behaviour deficits and long term mitochondrial alterationsClin Exp Pharmacol Physiol. 2016 Nov;43(11):1107-1114. doi: 10.1111\/1440-1681.12650.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: CD-1
Assessments: Elevated plus maze test, Histology, Novel object recognition test, Open field test, T-Maze, Western blot, infarct volume
Citation: Farr SA, Cuzzocrea S, Esposito E, Campolo M, Niehoff ML, Doyle TM, Salvemini D. Adenosine A(3) receptor as a novel therapeutic target to reduce secondary events and improve neurocognitive functions following traumatic brain injuryJ Neuroinflammation. 2020 Nov 12;17(1):339. doi: 10.1186\/s12974-020-02009-7. PMC7659122
TBI Model Type: Other
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, microsensor probe
Citation: Engelborghs K, Verlooy J, Van Reempts J, Van Deuren B, Van de Ven M, Borgers M. Temporal changes in intracranial pressure in a modified experimental model of closed head injuryJ Neurosurg. 1998 Nov;89(5):796-806. doi: 10.3171\/jns.1998.89.5.0796.
TBI Model Type: Other
Organism Species: pig
Organism Strain: Yorkshire
Assessments: Histology, Hematoxylin and Eosin
Citation: Duhaime AC, Margulies SS, Durham SR, O'Rourke MM, Golden JA, Marwaha S, Raghupathi R. Maturation-dependent response of the piglet brain to scaled cortical impactJ Neurosurg. 2000 Sep;93(3):455-62. doi: 10.3171\/jns.2000.93.3.0455.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Apnea, Histology, self-righting reflex
Citation: Brady RD, Grills BL, Church JE, Walsh NC, McDonald AC, Agoston DV, Sun M, O'Brien TJ, Shultz SR, McDonald SJ. Closed head experimental traumatic brain injury increases size and bone volume of callus in mice with concomitant tibial fractureSci Rep. 2016 Sep 29;6:34491. doi: 10.1038\/srep34491. PMC5041102
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: DTI data processing, Histology, Magnetic resonance imaging (MRI), Microscope analysis, Enzyme-linked immunosorbent assay (ELISA)
Citation: Singh K, Trivedi R, Devi MM, Tripathi RP, Khushu S. Longitudinal changes in the DTI measures, anti-GFAP expression and levels of serum inflammatory cytokines following mild traumatic brain injuryExp Neurol. 2016 Jan;275 Pt 3:427-435. doi: 10.1016\/j.expneurol.2015.07.016. Epub 2015 Jul 26.
