On page 1 showing 1 ~ 20 out of 24 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Behavioral, Cell viability, ELISA, Elevated Plus Maze, TNF-α assay, Y-Maze, cAMP assay, novel object recognition
Citation: Li Y, Glotfelty EJ, Namdar I, Tweedie D, Olson L, Hoffer BJ, DiMarchi RD, Pick CG, Greig NH.Neurotrophic and neuroprotective effects of a monomeric GLP-1/GIP/Gcg receptor triagonist in cellular and rodent models of mild traumatic brain injuryExp Neurol. 2020 Feb;324:113113. doi: 10.1016/j.expneurol.2019.113113. Epub 2019 Nov 12.10.1016/j.expneurol.2019.113113
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, Beam walk test, Morris water maze (MWM), Western blot, Immunohistochemistry (IHC)
Citation: Tian L, Guo R, Yue X, Lv Q, Ye X, Wang Z, Chen Z, Wu B, Xu G, Liu X.Brain Res. 2012 Feb 27;1440:47-55. doi: 10.1016/j.brainres.2011.12.059. Epub 2012 Jan 8.
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, Immunohistochemistry, LICOR imaging, Novel object recognition, Open field test, novel object placement memory tests, western blot analysis
Citation: Delic V, Karp JH, Guzman M, Arismendi GR, Stalnaker KJ, Burton JA, Murray KE, Stamos JP, Beck KD, Sokratian A, West AB, Citron BA.Acta Neuropathol Commun. 2022 Nov 26;10(1):170. doi: 10.1186/s40478-022-01475-9.10.1186/s40478-022-01475-9
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague Dawley
Assessments: ELISA, Immunohistochemistry
Citation: Dhir T, Weiss E, Wolanin K, Randhawa S, Samuel S, Minimo C, Becker G, McGreen B, Kriza C, Patel N, Kaplan M, Leung P.The impact of enoxaparin administration in relationship to hemorrhage in mild traumatic brain injuryInjury. 2018 Dec;49(12):2174-2177. doi: 10.1016/j.injury.2018.09.027. Epub 2018 Sep 14.10.1016/j.injury.2018.09.027
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, Brain water content, EMSA, rt-PCR, Immunohistochemistry (IHC), Western blot
Citation: Lv Q, Fan X, Xu G, Liu Q, Tian L, Cai X, Sun W, Wang X, Cai Q, Bao Y, Zhou L, Zhang Y, Ge L, Guo R, Liu X.Brain Res. 2013 Feb 1;1493:80-9. doi: 10.1016/j.brainres.2012.11.028. Epub 2012 Nov 23.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Nissl staning, Beam walk test, Bradford method, Immunohistochemistry (IHC), TUNEL staining, EMSA, ELISA, Immunofluorescence
Citation: Zhang D, Hu Y, Sun Q, Zhao J, Cong Z, Liu H, Zhou M, Li K, Hang C.Neuroscience. 2013 May 15;238:209-17. doi: 10.1016/j.neuroscience.2013.02.022. Epub 2013 Feb 24.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, Immunofluorescence, Lesion volume, Nissl staining, Beam balance test, Brain water content, Prehensile traction test
Citation: Zhao GW, Wang Y, Li YC, Jiang ZL, Sun L, Xi X, He P, Wang GH, Xu SH, Ma DM, Ke KF.J Ethnopharmacol. 2014;151(1):694-703. doi: 10.1016/j.jep.2013.11.041. Epub 2013 Dec 1.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: ELISA, Neurological Severity Score, TUNEL histochemistry, immunohistochemistry, real-time RT-PCR
Citation: Leinhase I, Rozanski M, Harhausen D, Thurman JM, Schmidt OI, Hossini AM, Taha ME, Rittirsch D, Ward PA, Holers VM, Ertel W, Stahel PF.Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in miceJ Neuroinflammation. 2007 May 2;4:13. doi: 10.1186/1742-2094-4-13.PMC186780810.1186/1742-2094-4-13
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, reverse-transcriptase polymerase chain reaction
Citation: Kamm K, Vanderkolk W, Lawrence C, Jonker M, Davis AT.The effect of traumatic brain injury upon the concentration and expression of interleukin-1beta and interleukin-10 in the ratJ Trauma. 2006 Jan;60(1):152-7. doi: 10.1097/01.ta.0000196345.81169.a1.10.1097/01.ta.0000196345.81169.a1
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: ELISA, H & E staining, Luxol fast blue staining, Nogo-A mRNA assay, RT-PCR, Water content, Western blot analysis
Citation: Chao PK, Lu KT, Jhu JY, Wo YY, Huang TC, Ro LS, Yang YL.Indomethacin protects rats from neuronal damage induced by traumatic brain injury and suppresses hippocampal IL-1β release through the inhibition of Nogo-A expressionJ Neuroinflammation. 2012 Jun 7;9:121. doi: 10.1186/1742-2094-9-121.PMC341669510.1186/1742-2094-9-121
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wister
Assessments: ELISA
Citation: DeKosky ST, Goss JR, Miller PD, Styren SD, Kochanek PM, Marion D.Upregulation of nerve growth factor following cortical traumaExp Neurol. 1994 Dec;130(2):173-7. doi: 10.1006/exnr.1994.1196.10.1006/exnr.1994.1196
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague–Dawley
Assessments: BBB permeability, ELISA, Electron microscopy, Gravimetric analysis, Neurochemical assays, Nissl staining, Western blot analysis, beam-balancing test, immunohistochemistry
Citation: Wang GH, Jiang ZL, Li YC, Li X, Shi H, Gao YQ, Vosler PS, Chen J.Free-radical scavenger edaravone treatment confers neuroprotection against traumatic brain injury in ratsJ Neurotrauma. 2011 Oct;28(10):2123-34. doi: 10.1089/neu.2011.1939. Epub 2011 Sep 27.PMC319136810.1089/neu.2011.1939
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: ELISA, EMSA, Immunohistochemistry (IHC), lactulose/mannitol (L/M) test, limulus amebocyte lysate (LAL) test
Citation: Jin W, Wang H, Ji Y, Hu Q, Yan W, Chen G, Yin H.Cytokine. 2008 Oct;44(1):135-40. doi: 10.1016/j.cyto.2008.07.005. Epub 2008 Aug 21.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: ELISA, TUNEL staining, Grip test, rt-PCR
Citation: Jin W, Wang H, Yan W, Zhu L, Hu Z, Ding Y, Tang K.J Neurotrauma. 2009 Jan;26(1):131-9. doi: 10.1089/neu.2008.0655.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: CCX872 pharmacokinetic analysis, ELISA, fluorescent imaging, qRT-PCR, radial arm water maze
Citation: Morganti JM, Jopson TD, Liu S, Riparip LK, Guandique CK, Gupta N, Ferguson AR, Rosi S.J Neurosci. 2015 Jan 14;35(2):748-60. doi: 10.1523/JNEUROSCI.2405-14.2015.10.1523/JNEUROSCI.2405-14.2015
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Behavioral, Conditioned – Avoidance (CA) test, ELISA, Hematoxylin and Eosin, Histopathological, Nissl staining, Swimming test, Toluidine blue stain, Western blotting
Citation: El-Gazar AA, Soubh AA, Mohamed EA, Awad AS, El-Abhar HS.Morin post-treatment confers neuroprotection in a novel rat model of mild repetitive traumatic brain injury by targeting dementia markers, APOE, autophagy and Wnt/β-catenin signaling pathwayBrain Res. 2019 Aug 15;1717:104-116. doi: 10.1016/j.brainres.2019.04.003. Epub 2019 Apr 16.10.1016/j.brainres.2019.04.003
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, ELISA, Morris water maze (MWM), qrt-PCR, Western blot, Immunofluorescence, hematoxylin and eosin, Inclined plane test, modified Neurologic Severity Score (mNSS)
Citation: Mao SS, Hua R, Zhao XP, Qin X, Sun ZQ, Zhang Y, Wu YQ, Jia MX, Cao JL, Zhang YM.J Neurotrauma. 2012 Jul 1;29(10):1941-59. doi: 10.1089/neu.2011.2244.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57/BL6
Assessments: ELISA, Histology, Magnetic Resonance Imaging, Novel object recognition, righting reflex response, rotarod
Citation: Yang SH, Gustafson J, Gangidine M, Stepien D, Schuster R, Pritts TA, Goodman MD, Remick DG, Lentsch AB.A murine model of mild traumatic brain injury exhibiting cognitive and motor deficitsJ Surg Res. 2013 Oct;184(2):981-8. doi: 10.1016/j.jss.2013.03.075. Epub 2013 Apr 18.PMC407378610.1016/j.jss.2013.03.075
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Western blot, ELISA
Citation: Carballosa-Gonzalez MM, Vitores A, Hentall ID.Hindbrain raphe stimulation boosts cyclic adenosine monophosphate and signaling proteins in the injured spinal cord.Brain Res. 2014 Jan 16;1543:165-72. doi: 10.1016/j.brainres.2013.11.013. Epub 2013 Nov 16.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, EMSA, Immunohistochemistry (IHC), lactulose/mannitol (L/M) test, limulus amebocyte lysate (LAL) test
Citation: Hu SL, Hu R, Li F, Liu Z, Xia YZ, Cui GY, Feng H.Acta Neurochir Suppl. 2008;105:191-6. doi: 10.1007/978-3-211-09469-3_37.
