On page 1 showing 1 ~ 19 out of 19 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay (ELISA), Elevated plus maze, Immunofluorescence, open field test, TUNEL staining, Western blot
Citation: Xie LL, Li SS, Fan YJ, Qi MM, Li ZZ. Melatonin alleviates traumatic brain injury-induced anxiety-like behaviors in rats: Roles of the protein kinase A\/cAMP-response element binding signaling pathwayExp Ther Med. 2022 Apr;23(4):248. doi: 10.3892\/etm.2022.11173. Epub 2022 Jan 31. PMC8855513
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Elevated plus maze, Forced swim test, Horizontal ladder beam, Immunohistochemistry (IHC), Morris Water Maze (MWM), Rotarod, Tail suspension test, Western Blots, optical fractionator probe
Citation: Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ. Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral DeficitsASN Neuro. 2018 Jan-Dec;10:1759091418781921. doi: 10.1177\/1759091418781921. PMC6050992
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Elevated plus maze, Forced swim test, Horizontal ladder beam, Immunohistochemistry (IHC), Morris Water Maze (MWM), Rotarod, Tail suspension test, Western Blots, optical fractionator probe
Citation: Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ. Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral DeficitsASN Neuro. 2018 Jan-Dec;10:1759091418781921. doi: 10.1177\/1759091418781921. PMC6050992
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Han
Assessments: RT-PCR, elevated plus maze, Barnes Maze test, Microarray, Rotarod test, Enzyme-linked immunosorbent assay (ELISA), rotating pole
Citation: Chakraborty N, Hammamieh R, Gautam A, Miller SA, Condlin ML, Jett M, Scrimgeour AG. TBI weight-drop model with variable impact heights differentially perturbs hippocampus-cerebellum specific transcriptomic profileExp Neurol. 2021 Jan;335:113516. doi: 10.1016\/j.expneurol.2020.113516. Epub 2020 Oct 22.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: in-house bred
Assessments: Beam walk test, Elevated plus maze, Forced swim test, Novel context mismatch test, open field test, qRT-PCR
Citation: Mychasiuk R, Hehar H, Candy S, Ma I, Esser MJ. The direction of the acceleration and rotational forces associated with mild traumatic brain injury in rodents effect behavioural and molecular outcomesJ Neurosci Methods. 2016 Jan 15;257:168-78. doi: 10.1016\/j.jneumeth.2015.10.002. Epub 2015 Oct 17.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Beam walk test, Elevated plus maze, Forced swim test, Novel context mismatch test, open field test, qRT-PCR
Citation: Kahriman A, Bouley J, Bosco DA, Shazeeb MS, Henninger N. Differential association of baseline body weight and body-weight loss with neurological deficits, histology, and death after repetitive closed head traumatic brain injuryNeurosci Lett. 2022 Feb 6;771:136430. doi: 10.1016\/j.neulet.2021.136430. Epub 2021 Dec 29. PMC8821174
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Behavioral, Cell viability, ELISA, Elevated Plus Maze, TNF-α assay, Y-Maze, cAMP assay, novel object recognition
Citation: Li Y, Glotfelty EJ, Namdar I, Tweedie D, Olson L, Hoffer BJ, DiMarchi RD, Pick CG, Greig NH.Neurotrophic and neuroprotective effects of a monomeric GLP-1/GIP/Gcg receptor triagonist in cellular and rodent models of mild traumatic brain injuryExp Neurol. 2020 Feb;324:113113. doi: 10.1016/j.expneurol.2019.113113. Epub 2019 Nov 12.10.1016/j.expneurol.2019.113113
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Elevated Plus Maze, Novel Object Recognition, Western Blot
Citation: Rubovitch V, Pharayra A, Har-Even M, Dvir O, Mattson MP, Pick CG.Dietary Energy Restriction Ameliorates Cognitive Impairment in a Mouse Model of Traumatic Brain InjuryJ Mol Neurosci. 2019 Apr;67(4):613-621. doi: 10.1007/s12031-019-01271-6. Epub 2019 Feb 8.PMC658839710.1007/s12031-019-01271-6
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Beam walking, Elevated plus maze, Morris water maze, Novel object recognition, Western blot
Citation: Lai JH, Karlsson TE, Wu JC, Huang CZ, Chen YH, Kang SJ, Brodin ATS, Hoffer BJ, Olson L, Chiang YH, Chen KY.Role of Nogo Receptor-1 for Recovery of Balance, Cognition, and Emotion after Mild Traumatic Brain Injury in MiceJ Neurotrauma. 2019 Apr 1;36(7):1054-1059. doi: 10.1089/neu.2018.5949. Epub 2018 Nov 17.10.1089/neu.2018.5949
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Duration of unconsciousness, Elevated Plus Maze, H-reflex, Morris Water Maze (MWM), T2-weighted Magnetic resonance imaging (MRI), Rotorod test
Citation: Hou J, Nelson R, Wilkie Z, Mustafa G, Tsuda S, Thompson FJ, Bose P. Mild and Mild-to-Moderate Traumatic Brain Injury-Induced Significant Progressive and Enduring Multiple ComorbiditiesJ Neurotrauma. 2017 Aug 15;34(16):2456-2466. doi: 10.1089\/neu.2016.4851. Epub 2017 Jun 9.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Electroencephalography, Morris Water Maze (MWM), Neurological Severity Score (NSS), Porsolt forced swim test, electromyography, elevated plus maze, tail suspension test, wire grip test
Citation: Petraglia AL, Plog BA, Dayawansa S, Chen M, Dashnaw ML, Czerniecka K, Walker CT, Viterise T, Hyrien O, Iliff JJ, Deane R, Nedergaard M, Huang JH. The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: a novel mouse model of chronic traumatic encephalopathyJ Neurotrauma. 2014 Jul 1;31(13):1211-24. doi: 10.1089\/neu.2013.3255. Epub 2014 Jun 12. PMC4082360
TBI Model Type: Other
Organism Species: rat
Organism Strain: in-house bred
Assessments: Beam walk test, Elevated plus maze, Forced swim test, Novel context mismatch test, open field test, qRT-PCR
Citation: Mychasiuk R, Hehar H, Candy S, Ma I, Esser MJ. The direction of the acceleration and rotational forces associated with mild traumatic brain injury in rodents effect behavioural and molecular outcomesJ Neurosci Methods. 2016 Jan 15;257:168-78. doi: 10.1016\/j.jneumeth.2015.10.002. Epub 2015 Oct 17.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6N
Assessments: Elevated plus maze, Histology, Immunohistochemistry (IHC), open field test, Paw preference test, handedness, Neurological Severity Score (NSS)
Citation: Lopez-Caperuchipi S, Kürzinger L, Hopp-Krämer S, Albert-Weißenberger C, Paul MM, Sirén AL, Stetter C. Posttraumatic learning deficits correlate with initial trauma severity and chronic cellular reactions after closed head injury in male miceExp Neurol. 2021 Jul;341:113721. doi: 10.1016\/j.expneurol.2021.113721. Epub 2021 Apr 11.
TBI Model Type: Blast model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Elevated Plus Maze, Immunohistochemistry (IHC), Histology, Three-Chamber Sociability Test
Citation: Dickerson MR, Murphy SF, Urban MJ, White Z, VandeVord PJ. Chronic Anxiety- and Depression-Like Behaviors Are Associated With Glial-Driven Pathology Following Repeated Blast Induced NeurotraumaFront Behav Neurosci. 2021 Dec 10;15:787475. doi: 10.3389\/fnbeh.2021.787475. eCollection 2021. PMC8703020
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Behavioral, Western blotting, beam walk, elevated plus maze, forced swim, multi-plex enzyme-linked immunosorbent assay, novel context mismatch, quantitative polymerase chain reaction
Citation: Fraunberger EA, DeJesus P, Zanier ER, Shutt TE, Esser MJ.Acute and Persistent Alterations of Cerebellar Inflammatory Networks and Glial Activation in a Rat Model of Pediatric Mild Traumatic Brain InjuryJ Neurotrauma. 2020 Jun 1;37(11):1315-1330. doi: 10.1089/neu.2019.6714. Epub 2020 Feb 25.10.1089/neu.2019.6714
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Electrophysiology, Elevated plus maze, Immunohistochemistry, Magnetic resonance image, modified Barnes maze, three-chamber social approach task
Citation: Nolan A, Hennessy E, Krukowski K, Guglielmetti C, Chaumeil MM, Sohal VS, Rosi S.J Neurotrauma. 2018 Oct 15;35(20):2425-2434. doi: 10.1089/neu.2018.5731. Epub 2018 Jul 2.10.1089/neu.2018.5731
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57B6/J
Assessments: Lesion Analysis, elevated plus maze, novel object recognition assay, rule shift assay, social approach task
Citation: Chou A, Morganti JM, Rosi S.PLoS One. 2016 Mar 10;11(3):e0151418. doi: 10.1371/journal.pone.0151418. eCollection 2016.10.1371/journal.pone.0151418
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57/BL6J
Assessments: Elevated plus maze, Forced swim tests, Immunohistochemistry, Morris Water Maze, Open field test, Western blot analysis, rotarod testing, sucrose preference test
Citation: Wu L, Kalish BT, Finander B, Cao T, Jin G, Yahya T, Levy ES, Kukreja B, LaRovere ES, Chung JY, Lo EH, Brown-Whalen A, El Khoury J, Kaplan DL, Whalen MJ.J Neurosci. 2022 Mar 23;42(12):2418-2432. doi: 10.1523/JNEUROSCI.0682-21.2021. Epub 2022 Feb 1.10.1523/JNEUROSCI.0682-21.2021
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Behavioral, Elevated plus maze, Fluoro-Jade, Immunohistochemical staining, Novel object recognition, Y-maze, pharmacokinetic
Citation: Bader M, Li Y, Lecca D, Rubovitch V, Tweedie D, Glotfelty E, Rachmany L, Kim HK, Choi HI, Hoffer BJ, Pick CG, Greig NH, Kim DS.Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injuryNeurobiol Dis. 2019 Apr;124:439-453. doi: 10.1016/j.nbd.2018.11.023. Epub 2018 Nov 22.PMC671083110.1016/j.nbd.2018.11.023
