On page 1 showing 1 ~ 20 out of 20 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6-SJL
Assessments: Array image analysis, Beam walk test, Cytokine array, Immunohistochemistry (IHC), Neurological Severity Score (NSS), confocal imaging, phospho-Akt array
Citation: Chandrasekar A, Heuvel FO, Palmer A, Linkus B, Ludolph AC, Boeckers TM, Relja B, Huber-Lang M, Roselli F. Acute ethanol administration results in a protective cytokine and neuroinflammatory profile in traumatic brain injuryInt Immunopharmacol. 2017 Oct;51:66-75. doi: 10.1016\/j.intimp.2017.08.002. Epub 2017 Aug 12.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam balance test, Morris Water Maze (MWM), Beam walk test
Citation: Dixon CE, Clifton GL, Lighthall JW, Yaghmai AA, Hayes RL. A controlled cortical impact model of traumatic brain injury in the ratJ Neurosci Methods. 1991 Oct;39(3):253-62. doi: 10.1016\/0165-0270(91)90104-8.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam walk test, open field test, Five serial choice reaction time task, time-to-right
Citation: Mychasiuk R, Hehar H, Esser MJ. A mild traumatic brain injury (mTBI) induces secondary attention-deficit hyperactivity disorder-like symptomology in young ratsBehav Brain Res. 2015 Jun 1;286:285-92. doi: 10.1016\/j.bbr.2015.03.010. Epub 2015 Mar 11.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Harlan
Assessments: Beam balance test, Morris Water Maze (MWM), Beam task test, Beam walk test
Citation: Cheng JP, Shaw KE, Monaco CM, Hoffman AN, Sozda CN, Olsen AS, Kline AE. A relatively brief exposure to environmental enrichment after experimental traumatic brain injury confers long-term cognitive benefitsJ Neurotrauma. 2012 Nov 20;29(17):2684-8. doi: 10.1089\/neu.2012.2560. Epub 2012 Aug 27. PMC3510443
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam walk test, Western blot, accelerometer, modified Neurological Severity Score (mNSS)
Citation: Hsieh TH, Kang JW, Lai JH, Huang YZ, Rotenberg A, Chen KY, Wang JY, Chan SY, Chen SC, Chiang YH, Peng CW. Relationship of mechanical impact magnitude to neurologic dysfunction severity in a rat traumatic brain injury modelPLoS One. 2017 May 26;12(5):e0178186. doi: 10.1371\/journal.pone.0178186. eCollection 2017. PMC5446124
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6 (transgenic)
Assessments: Neurological Severity Score (NSS), Beam walk test, Blood ethanol assay, Blood gas analysis, Blood glial fibrillary acidic protein, Confocal images, Immunostaining, nitrocellulose-membrane sandwich immunoassay
Citation: Chandrasekar A, Olde Heuvel F, Wepler M, Rehman R, Palmer A, Catanese A, Linkus B, Ludolph A, Boeckers T, Huber-Lang M, Radermacher P, Roselli F. The Neuroprotective Effect of Ethanol Intoxication in Traumatic Brain Injury Is Associated with the Suppression of ErbB Signaling in Parvalbumin-Positive InterneuronsJ Neurotrauma. 2018 Nov 15;35(22):2718-2735. doi: 10.1089\/neu.2017.5270. Epub 2018 Jul 23.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: hindlimb reflexive ability, single probe trial, Cortical lesion volume, Morris Mater Maze (MWM), Beam balance test, Beam walk test, righting reflex, Rotarod test, Cresyl violet staining
Citation: Monaco CM, Mattiola VV, Folweiler KA, Tay JK, Yelleswarapu NK, Curatolo LM, Matter AM, Cheng JP, Kline AE. Environmental enrichment promotes robust functional and histological benefits in female rats after controlled cortical impact injuryExp Neurol. 2013 Sep;247:410-8. doi: 10.1016\/j.expneurol.2013.01.007. Epub 2013 Jan 16. PMC3644389
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: in-house bred
Assessments: Beam walk test, Elevated plus maze, Forced swim test, Novel context mismatch test, open field test, qRT-PCR
Citation: Mychasiuk R, Hehar H, Candy S, Ma I, Esser MJ. The direction of the acceleration and rotational forces associated with mild traumatic brain injury in rodents effect behavioural and molecular outcomesJ Neurosci Methods. 2016 Jan 15;257:168-78. doi: 10.1016\/j.jneumeth.2015.10.002. Epub 2015 Oct 17.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: 1H-MRS, Beam walk test, LC Model, Magnetic resonance imaging (MRI), Novel object recognition test, Open field exploratory
Citation: Singh K, Trivedi R, Haridas S, Manda K, Khushu S. Study of neurometabolic and behavioral alterations in rodent model of mild traumatic brain injury: a pilot studyNMR Biomed. 2016 Dec;29(12):1748-1758. doi: 10.1002\/nbm.3627. Epub 2016 Oct 25.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Beam walk test, Elevated plus maze, Forced swim test, Novel context mismatch test, open field test, qRT-PCR
Citation: Kahriman A, Bouley J, Bosco DA, Shazeeb MS, Henninger N. Differential association of baseline body weight and body-weight loss with neurological deficits, histology, and death after repetitive closed head traumatic brain injuryNeurosci Lett. 2022 Feb 6;771:136430. doi: 10.1016\/j.neulet.2021.136430. Epub 2021 Dec 29. PMC8821174
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, Beam walk test, Morris water maze (MWM), Western blot, Immunohistochemistry (IHC)
Citation: Tian L, Guo R, Yue X, Lv Q, Ye X, Wang Z, Chen Z, Wu B, Xu G, Liu X.Brain Res. 2012 Feb 27;1440:47-55. doi: 10.1016/j.brainres.2011.12.059. Epub 2012 Jan 8.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Nissl staning, Beam walk test, Bradford method, Immunohistochemistry (IHC), TUNEL staining, EMSA, ELISA, Immunofluorescence
Citation: Zhang D, Hu Y, Sun Q, Zhao J, Cong Z, Liu H, Zhou M, Li K, Hang C.Neuroscience. 2013 May 15;238:209-17. doi: 10.1016/j.neuroscience.2013.02.022. Epub 2013 Feb 24.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam walk test, Morris Water Maze (MWM), Beam balance test
Citation: Statler KD, Alexander H, Vagni V, Holubkov R, Dixon CE, Clark RS, Jenkins L, Kochanek PM. Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injuryBrain Res. 2006 Mar 3;1076(1):216-24. doi: 10.1016\/j.brainres.2005.12.106. Epub 2006 Feb 13.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Neurological evaluation, Histology, Immunohistochemistry (IHC), Morris Water Maze (MWM), Beam walk test, forepaw contraflexion, Rotarod test, TUNEL staining
Citation: Fox GB, Fan L, Levasseur RA, Faden AI. Sustained sensory\/motor and cognitive deficits with neuronal apoptosis following controlled cortical impact brain injury in the mouseJ Neurotrauma. 1998 Aug;15(8):599-614. doi: 10.1089\/neu.1998.15.599.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Beam walk test, Immunofluorescent, Immunohistochemistry (IHC), Lesion Volume Assessment, Morris Water Maze (MWM)
Citation: Huang SX, Qiu G, Cheng FR, Pei Z, Yang Z, Deng XH, Zhu JH, Chen L, Chen CC, Lin WF, Liu Y, Liu Z, Zhu FQ. Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory ModulationNeurochem Res. 2018 Sep;43(9):1814-1825. doi: 10.1007\/s11064-018-2597-5. Epub 2018 Jul 19.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Histology, Morris Water Maze (MWM), Beam balance test, Beam walk test, memory retention, rotarod
Citation: Hill JL, Kobori N, Zhao J, Rozas NS, Hylin MJ, Moore AN, Dash PK. Traumatic brain injury decreases AMP-activated protein kinase activity and pharmacological enhancement of its activity improves cognitive outcomeJ Neurochem. 2016 Oct;139(1):106-19. doi: 10.1111\/jnc.13726. Epub 2016 Aug 1. PMC5037010
TBI Model Type: Other
Organism Species: rat
Organism Strain: in-house bred
Assessments: Beam walk test, Elevated plus maze, Forced swim test, Novel context mismatch test, open field test, qRT-PCR
Citation: Mychasiuk R, Hehar H, Candy S, Ma I, Esser MJ. The direction of the acceleration and rotational forces associated with mild traumatic brain injury in rodents effect behavioural and molecular outcomesJ Neurosci Methods. 2016 Jan 15;257:168-78. doi: 10.1016\/j.jneumeth.2015.10.002. Epub 2015 Oct 17.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam walk test, Estimated contusion volume, Nissl staining, Neuronal death, Gliosis rating, Tactile placing
Citation: Stibick DL, Feeney DM.J Neurotrauma. 2001 Mar;18(3):303-12. doi: 10.1089/08977150151070955.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6-SJL
Assessments: Beam walk test, Blood ethanol level, Confocal imaging, Neurological Severity Score (NSS), open field test, qRT-PCR, Western blot, histology
Citation: Chandrasekar A, Aksan B, Heuvel FO, Förstner P, Sinske D, Rehman R, Palmer A, Ludolph A, Huber-Lang M, Böckers T, Mauceri D, Knöll B, Roselli F. Neuroprotective effect of acute ethanol intoxication in TBI is associated to the hierarchical modulation of early transcriptional responsesExp Neurol. 2018 Apr;302:34-45. doi: 10.1016\/j.expneurol.2017.12.017. Epub 2018 Jan 4.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Balb/C
Assessments: Fluoro-Jade B staining, Beam walk test, hematoxylin and eosin
Citation: Lopez NE, Gaston L, Lopez KR, Hageny AM, Putnam J, Eliceiri B, Coimbra R, Bansal V.J Surg Res. 2014 Mar;187(1):230-236. doi: 10.1016/j.jss.2013.09.030. Epub 2013 Oct 7.
