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On page 9 showing 161 ~ 180 out of 226 results
Snippet Table

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Immunofluorescence, Neurological evaluation, Nissl Staining, Western blot, modified Garcia method
Citation: He GY, Zhao CH, Wu DG, Cheng H, Sun LA, Zhang DL, Yang XJ, Fan XR, Di GF, Jiang XC. S100A8 Promotes Inflammation via Toll-Like Receptor 4 After Experimental Traumatic Brain InjuryFront Neurosci. 2021 Feb 3;14:616559. doi: 10.3389\/fnins.2020.616559. eCollection 2020. PMC7887321

TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: AP firing patterns, AP threshold, Electrophysiological recordings, Input resistance, Resting membrane potential, Spontaneous neuronal activity, action potential generation, fast after-hyperpolarizations, hyperpolarization-activated cation current recordings, infrared-differential interference contrast microscopy
Citation: Simmons S, Langlois LD, Oyola MG, Gouty S, Wu TJ, Nugent FS. Blast-Induced Mild Traumatic Brain Injury Alterations of Corticotropin-Releasing Factor Neuronal Activity in the Mouse Hypothalamic Paraventricular NucleusFront Synaptic Neurosci. 2022 Jan 27;13:804898. doi: 10.3389\/fnsyn.2021.804898. eCollection 2021. PMC8828487

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Dichlorofluorescein Diacetate Dye, Immunofluorescence, Neurological Severity Score )NSS), Nissl staining, TUNEL staining, Western Blot, Optical density, qRT-PCR
Citation: Yang XJ, Ling S, Zhou ML, Deng HJ, Qi M, Liu XL, Zhen C, Chen YX, Fan XR, Wu ZY, Ma FC, Rong J, Di GF, Jiang XC. Inhibition of TRPA1 Attenuates Oxidative Stress-induced Damage After Traumatic Brain Injury via the ERK\/AKT Signaling PathwayNeuroscience. 2022 Feb 11;494:51-68. doi: 10.1016\/j.neuroscience.2022.02.003. Online ahead of print.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: CD-1
Assessments: RayBiotech cytokine array, SOMA scan assay
Citation: Tweedie D, Karnati HK, Mullins R, Pick CG, Hoffer BJ, Goetzl EJ, Kapogiannis D, Greig NH. Time-dependent cytokine and chemokine changes in mouse cerebral cortex following a mild traumatic brain injuryElife. 2020 Aug 17;9:e55827. doi: 10.7554\/eLife.55827. PMC7473773

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Enzyme-linked immunosorbent assay (ELISA), Immunofluorescence, Novel object recognition test, Toluidine Blue stain, crystal violet staining
Citation: Kempuraj D, Ahmed ME, Selvakumar GP, Thangavel R, Raikwar SP, Zaheer SA, Iyer SS, Burton C, James D, Zaheer A. Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain InjuryMediators Inflamm. 2020 Jun 24;2020:4243953. doi: 10.1155\/2020\/4243953. eCollection 2020. PMC7333064

TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6-C3F1/J transgenic
Assessments: Amyloid burden, Astrocytic end feet contacts estimation, Capillary density estimation, Immunohistochemistry (IHC), Pericyte estimation, Histology
Citation: Clark AT, Abrahamson EE, Harper MM, Ikonomovic MD. Chronic effects of blast injury on the microvasculature in a transgenic mouse model of Alzheimer's disease related Aβ amyloidosisFluids Barriers CNS. 2022 Jan 10;19(1):5. doi: 10.1186\/s12987-021-00301-z. PMC8751260

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, M29, 79-dichlorodihydrofluorescein diacetate (DCFH-DA) staining, Morris Water Maze, Neurological Severity Scores, Nissl staining, TdT-mediated dUTP Nick-End Labeling, We performed modified Neurological Severity Scores (mNSS), rotarod test, and Morris Water Maze (MWM) test, respectively (n = 8 for each group), enzyme linked immunosorbent assay, immunofluorescence, immunohistochemistry, quantitative real time polymerase chain reaction, rotarod test, western blot
Citation: Wang H, Zhou XM, Wu LY, Liu GJ, Xu WD, Zhang XS, Gao YY, Tao T, Zhou Y, Lu Y, Wang J, Deng CL, Zhuang Z, Hang CH, Li W.Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injuryJ Neuroinflammation. 2020 Jun 15;17(1):188. doi: 10.1186/s12974-020-01863-9.PMC729463110.1186/s12974-020-01863-9

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Neuropsychiatric, Rotarod, forced swim test, immunohistochemistry
Citation: Niziolek GM, Boudreau RM, Baker J, Friend LA, Makley AT, Edwards MJ, Gulbins E, Goodman MD.Acid Sphingomyelinase Inhibition Mitigates Histopathological and Behavioral Changes in a Murine Model of Traumatic Brain InjuryJ Neurotrauma. 2020 Sep 1;37(17):1902-1909. doi: 10.1089/neu.2019.6436. Epub 2020 May 4.PMC748489510.1089/neu.2019.6436

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: EEG
Citation: Shandra O, Robel S.Inducing Post-Traumatic Epilepsy in a Mouse Model of Repetitive Diffuse Traumatic Brain InjuryJ Vis Exp. 2020 Feb 10;(156):10.3791/60360. doi: 10.3791/60360.PMC967733110.3791/60360

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Behavioral, Elevated Plus Maze Paradigm, Fluoro Jade B, Immunohistochemistry, Novel Object Recognition Paradigm, Western Blotting, Y-Maze Paradigm, glial fibrillary acidic protein, neuronal nuclear antigen
Citation: Bader M, Li Y, Tweedie D, Shlobin NA, Bernstein A, Rubovitch V, Tovar-Y-Romo LB, DiMarchi RD, Hoffer BJ, Greig NH, Pick CG.Neuroprotective Effects and Treatment Potential of Incretin Mimetics in a Murine Model of Mild Traumatic Brain InjuryFront Cell Dev Biol. 2020 Jan 10;7:356. doi: 10.3389/fcell.2019.00356. eCollection 2019.PMC696503110.3389/fcell.2019.00356

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain Water, H & E stain, Immunofluorescence, Immunohistochemistry, Western Blot
Citation: Yi HJ, Lee JE, Lee DH, Kim YI, Cho CB, Kim IS, Sung JH, Yang SH.The role of NLRP3 in traumatic brain injury and its regulation by pioglitazoneJ Neurosurg. 2019 Sep 27;133(4):1083-1091. doi: 10.3171/2019.6.JNS1954. Print 2020 Oct 1.10.3171/2019.6.JNS1954

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: CCX872 pharmacokinetic analysis, ELISA, fluorescent imaging, qRT-PCR, radial arm water maze
Citation: Morganti JM, Jopson TD, Liu S, Riparip LK, Guandique CK, Gupta N, Ferguson AR, Rosi S.J Neurosci. 2015 Jan 14;35(2):748-60. doi: 10.1523/JNEUROSCI.2405-14.2015.10.1523/JNEUROSCI.2405-14.2015

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57B6/J
Assessments: Radial Arm Water Maze, qRT-PCR
Citation: Chou A, Krukowski K, Morganti JM, Riparip LK, Rosi S.Int J Mol Sci. 2018 May 30;19(6):1616. doi: 10.3390/ijms19061616.10.3390/ijms19061616

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57/BL6
Assessments: MR data analysis, Spectrophotometric assays, immunofluorescence analyses
Citation: Guglielmetti C, Chou A, Krukowski K, Najac C, Feng X, Riparip LK, Rosi S, Chaumeil MM.Sci Rep. 2017 Dec 13;7(1):17525. doi: 10.1038/s41598-017-17758-4.10.1038/s41598-017-17758-4

Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Electrophysiology, Elevated plus maze, Immunohistochemistry, Magnetic resonance image, modified Barnes maze, three-chamber social approach task
Citation: Nolan A, Hennessy E, Krukowski K, Guglielmetti C, Chaumeil MM, Sohal VS, Rosi S.J Neurotrauma. 2018 Oct 15;35(20):2425-2434. doi: 10.1089/neu.2018.5731. Epub 2018 Jul 2.10.1089/neu.2018.5731

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Rotational Thromboelastometry
Citation: Morris MC, Kassam F, Bercz A, Beckmann N, Schumacher F, Gulbins E, Makley AT, Goodman MD.The Role of Chemoprophylactic Agents in Modulating Platelet Aggregability After Traumatic Brain InjuryJ Surg Res. 2019 Dec;244:1-8. doi: 10.1016/j.jss.2019.06.022. Epub 2019 Jul 3.PMC681570410.1016/j.jss.2019.06.022

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57B6/J
Assessments: Behavioral tests, Delayed-Matching-to-Place Paradigm, Electrophysiological recordings, Radial Arm Water Maze, Western Blotting, modified Barnes maze
Citation: Chou A, Krukowski K, Jopson T, Zhu PJ, Costa-Mattioli M, Walter P, Rosi S.Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6420-E6426. doi: 10.1073/pnas.1707661114. Epub 2017 Jul 10.10.1073/pnas.1707661114

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57B6/J
Assessments: Lesion Analysis, elevated plus maze, novel object recognition assay, rule shift assay, social approach task
Citation: Chou A, Morganti JM, Rosi S.PLoS One. 2016 Mar 10;11(3):e0151418. doi: 10.1371/journal.pone.0151418. eCollection 2016.10.1371/journal.pone.0151418

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Cognitive function—novel location recognition test, Immunohistochemistry, Open field test, Rotarod, Western blotting
Citation: Sekar S, Zhang Y, Miranzadeh Mahabadi H, Parvizi A, Taghibiglou C.Low-Field Magnetic Stimulation Restores Cognitive and Motor Functions in the Mouse Model of Repeated Traumatic Brain Injury: Role of Cellular Prion ProteinJ Neurotrauma. 2019 Nov 15;36(22):3103-3114. doi: 10.1089/neu.2018.5918. Epub 2019 Jun 6.10.1089/neu.2018.5918

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6J
Assessments: Behavioral, Histopathological, Morris Water Maze
Citation: Shishido H, Ueno M, Sato K, Matsumura M, Toyota Y, Kirino Y, Tamiya T, Kawai N, Kishimoto Y.Traumatic Brain Injury by Weight-Drop Method Causes Transient Amyloid-β Deposition and Acute Cognitive Deficits in MiceBehav Neurol. 2019 Mar 3;2019:3248519. doi: 10.1155/2019/3248519. eCollection 2019.PMC642181410.1155/2019/3248519

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The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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