On page 7 showing 121 ~ 140 out of 420 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Long Evans
Assessments: ELISA test, Immunohistochemistry, Morris water maze test, Novel object recognition test, open field test
Citation: Tadepalli SA, Bali ZK, Bruszt N, Nagy LV, Amrein K, Fazekas B, Büki A, Czeiter E, Hernádi I.Long-term cognitive impairment without diffuse axonal injury following repetitive mild traumatic brain injury in ratsBehav Brain Res. 2020 Jan 27;378:112268. doi: 10.1016/j.bbr.2019.112268. Epub 2019 Sep 30.10.1016/j.bbr.2019.112268
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague‐Dawley
Assessments: Brain water content, Enzyme‐linked immunosorbent assay, Immunohistochemical, Real‐time quantitative polymerase chain reaction, TUNEL, Terminal deoxynucleotidyl transferase‐mediated dUTP nick‐end labeling, Western blot, neurological severity score
Citation: Li F, Wang X, Zhang Z, Zhang X, Gao P.Dexmedetomidine Attenuates Neuroinflammatory-Induced Apoptosis after Traumatic Brain Injury via Nrf2 signaling pathwayAnn Clin Transl Neurol. 2019 Sep;6(9):1825-1835. doi: 10.1002/acn3.50878. Epub 2019 Sep 3.PMC676450110.1002/acn3.50878
TBI Model Type: Fluid percussion injury model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Immunohistochemistry, Neurological Severity Score, Olmos amino cupric silver (Ag) technique, Rotarod, Sleep recordings, forced swim task, morphology analysis, novel object recognition, open field task
Citation: Rowe RK, Harrison JL, Morrison HW, Subbian V, Murphy SM, Lifshitz J.J Neurotrauma. 2019 Apr 15;36(8):1318-1334. doi: 10.1089/neu.2018.5980. Epub 2018 Dec 18.10.1089/neu.2018.5980
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Evans blue, FABP7, Neurological score, brain edema, immunofluorescence staining, real-time PCR, western blotting
Citation: Rui Q, Ni H, Lin X, Zhu X, Li D, Liu H, Chen G.Astrocyte-derived fatty acid-binding protein 7 protects blood-brain barrier integrity through a caveolin-1/MMP signaling pathway following traumatic brain injuryExp Neurol. 2019 Dec;322:113044. doi: 10.1016/j.expneurol.2019.113044. Epub 2019 Aug 24.10.1016/j.expneurol.2019.113044
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57B6/J
Assessments: Flow synatocytometry, MR imaging, Novel Object Recognition, T2-weighted images, flow cytometry analyses, immunohistochemistry analysis, qPCR analysis
Citation: Krukowski K, Chou A, Feng X, Tiret B, Paladini MS, Riparip LK, Chaumeil MM, Lemere C, Rosi S.Int J Mol Sci. 2018 Nov 26;19(12):3753. doi: 10.3390/ijms19123753.10.3390/ijms19123753
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Immunofluorescence Staining, qRT-PCR
Citation: Morganti JM, Riparip LK, Rosi S.PLoS One. 2016 Jan 25;11(1):e0148001. doi: 10.1371/journal.pone.0148001. eCollection 2016.10.1371/journal.pone.0148001
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Dark neuron, Terminal deoxynucleotidyl transferase-mediated biotinylated dUTP nick-end labeling, Western blotting, modified Neurological Severity Score, western blot
Citation: Ghadiri T, Vakilzadeh G, Hajali V, Khodagholi F.Progesterone modulates post-traumatic epileptogenesis through regulation of BDNF-TrkB signaling and cell survival-related pathways in the rat hippocampusNeurosci Lett. 2019 Sep 14;709:134384. doi: 10.1016/j.neulet.2019.134384. Epub 2019 Jul 17.10.1016/j.neulet.2019.134384
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Hierarchical clustering analysis, Ingenuity Pathway Analysis, qRT-PCR
Citation: Morganti JM, Riparip LK, Chou A, Liu S, Gupta N, Rosi S.J Neuroinflammation. 2016 Apr 18;13(1):80. doi: 10.1186/s12974-016-0547-1.10.1186/s12974-016-0547-1
TBI Model Type: Weight-drop model
Organism Species: mouse
Assessments: Behavioral, Fluoro-Jade C, Immunofluorescence, Immunohistochemical, Laser scanning confocal microscopy, Long Term Potentiation, NOR, Y maze
Citation: Lecca D, Bader M, Tweedie D, Hoffman AF, Jung YJ, Hsueh SC, Hoffer BJ, Becker RE, Pick CG, Lupica CR, Greig NH.(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged miceNeurobiol Dis. 2019 Oct;130:104528. doi: 10.1016/j.nbd.2019.104528. Epub 2019 Jul 8.PMC671615210.1016/j.nbd.2019.104528
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain edema, Cell Death Assays, Enzyme-Linked Immunosorbent Assay, Evans Blue Dye Extravasation, Immunofluorescence Staining, Neurological, Real-Time PCR, Western Blotting, cresyl violet
Citation: Ni H, Rui Q, Lin X, Li D, Liu H, Chen G.2-BFI Provides Neuroprotection Against Inflammation and Necroptosis in a Rat Model of Traumatic Brain InjuryFront Neurosci. 2019 Jun 26;13:674. doi: 10.3389/fnins.2019.00674. eCollection 2019.PMC660678410.3389/fnins.2019.00674
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Western blot, immunohistochemical staining, neurological severity score, real-time quantitative polymerase chain reaction, terminal deoxynucleotidyl transferase dUTP nick end labeling assay
Citation: Li F, Wang X, Zhang Z, Gao P, Zhang X.Breviscapine provides a neuroprotective effect after traumatic brain injury by modulating the Nrf2 signaling pathwayJ Cell Biochem. 2019 Sep;120(9):14899-14907. doi: 10.1002/jcb.28751. Epub 2019 May 1.10.1002/jcb.28751
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Bioanalyzer DIANA mirPath, Histology, RT-PCR, qRT-PCR, Hematoxylin and Eosin
Citation: Chandran R, Sharma A, Bhomia M, Balakathiresan NS, Knollmann-Ritschel BE, Maheshwari RK. Differential expression of microRNAs in the brains of mice subjected to increasing grade of mild traumatic brain injuryBrain Inj. 2017;31(1):106-119. doi: 10.1080\/02699052.2016.1213420. Epub 2016 Nov 7.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beta-hydroxybutyrate level, Brainwater content, Cytochrome c assay, TUNEL staining, glucose measurement
Citation: Hu ZG, Wang HD, Jin W, Yin HX. Ketogenic diet reduces cytochrome c release and cellular apoptosis following traumatic brain injury in juvenile ratsAnn Clin Lab Sci. 2009 Winter;39(1):76-83.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay, Immunofluorescence staining, Lesion volume, Survival assay, Western blot, modified neurological severity score, scanning electron microscope
Citation: Hu J, Chen L, Huang X, Wu K, Ding S, Wang W, Wang B, Smith C, Ren C, Ni H, ZhuGe Q, Yang J.Calpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injuryStem Cell Res Ther. 2019 Mar 15;10(1):96. doi: 10.1186/s13287-019-1210-4.PMC642077510.1186/s13287-019-1210-4
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague – Dawley
Citation: Çetin A, Deveci E.Expression of vascular endothelial growth factor and glial fibrillary acidic protein in a rat model of traumatic brain injury treated with honokiol: a biochemical and immunohistochemical studyFolia Morphol (Warsz). 2019;78(4):684-694. doi: 10.5603/FM.a2019.0029. Epub 2019 Mar 5.10.5603/FM.a2019.0029
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ELISA, Beam walk test, Morris water maze (MWM), Western blot, Immunohistochemistry (IHC)
Citation: Tian L, Guo R, Yue X, Lv Q, Ye X, Wang Z, Chen Z, Wu B, Xu G, Liu X.Brain Res. 2012 Feb 27;1440:47-55. doi: 10.1016/j.brainres.2011.12.059. Epub 2012 Jan 8.
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Complete blood count, Quantifying fracture healing
Citation: Morioka K, Marmor Y, Sacramento JA, Lin A, Shao T, Miclau KR, Clark DR, Beattie MS, Marcucio RS, Miclau T 3rd, Ferguson AR, Bresnahan JC, Bahney CS.Sci Rep. 2019 Aug 21;9(1):12199. doi: 10.1038/s41598-019-48126-z.10.1038/s41598-019-48126-z
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Elevated Plus Maze, Novel Object Recognition, Western Blot
Citation: Rubovitch V, Pharayra A, Har-Even M, Dvir O, Mattson MP, Pick CG.Dietary Energy Restriction Ameliorates Cognitive Impairment in a Mouse Model of Traumatic Brain InjuryJ Mol Neurosci. 2019 Apr;67(4):613-621. doi: 10.1007/s12031-019-01271-6. Epub 2019 Feb 8.PMC658839710.1007/s12031-019-01271-6
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Glycerol Assay, Western blot, Brain water content
Citation: Ali A, Konakondla S, Zwagerman NT, Peng C, Schafer S, Ding JY, Dornbos D 3rd, Sikharam C, Geng X, Guthikonda M, Kreipke CW, Rafols JA, Ding Y.Neurol Res. 2012 Jun;34(5):462-8. doi: 10.1179/1743132812Y.0000000014. Epub 2012 Mar 20.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Image acquisition, Immunofluorescence, righting reflex, skeleton analysis method
Citation: White MR, VandeVord PJ.Front Cell Neurosci. 2023 Feb 15;17:1076851. doi: 10.3389/fncel.2023.1076851. eCollection 2023.10.3389/fncel.2023.1076851