On page 6 showing 101 ~ 120 out of 226 results
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6 x SV129
Assessments: Lesion volume, MWM, beam balance, immunohistochemically
Citation: Whalen MJ, Clark RS, Dixon CE, Robichaud P, Marion DW, Vagni V, Graham SH, Virag L, Hasko G, Stachlewitz R, Szabo C, Kochanek PM.Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase.J Cereb Blood Flow Metab. 1999 Aug;19(8):835-42. doi: 10.1097/00004647-199908000-00002.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Flow Cytometry, Platelet Counts, Viscoelastic coagulation
Citation: Morris MC, John D, Singer KE, Moran R, McGlone E, Veile R, Goetzman HS, Makley AT, Caldwell CC, Goodman MD.Post-TBI splenectomy may exacerbate coagulopathy and platelet activation in a murine modelThromb Res. 2020 Sep;193:211-217. doi: 10.1016/j.thromres.2020.08.002. Epub 2020 Aug 7.PMC748410510.1016/j.thromres.2020.08.002
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: CF-1
Assessments: Western blot, Silver staining
Citation: Kupina NC, Detloff MR, Bobrowski WF, Snyder BJ, Hall ED.Exp Neurol. 2003 Mar;180(1):55-73. doi: 10.1016/s0014-4886(02)00048-1.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Caspase Enzyme Activity, Feeding Latency, Histopathology, rt-PCR, TUNEL staining, Western blot
Citation: Mikrogianakis A, Shaye RE, Griffin P, Kawesa S, Lockwood J, Gendron NH, Gaboury I, Merali Z, Mackenzie AE, Hutchison JS.J Neurotrauma. 2007 Feb;24(2):338-53. doi: 10.1089/neu.2006.003615.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Balb/C
Assessments: Cerebral Tissue Damage, Histology, Neurologic Severity Score (NSS), TUNEL staining, Hematoxylin and eosin
Citation: Reshef A, Shirvan A, Shohami E, Grimberg H, Levin G, Cohen A, Trembovler V, Ziv I.J Neurotrauma. 2008 Jun;25(6):569-80. doi: 10.1089/neu.2007.0341.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: ELISA, EMSA, Immunohistochemistry (IHC), lactulose/mannitol (L/M) test, limulus amebocyte lysate (LAL) test
Citation: Jin W, Wang H, Ji Y, Hu Q, Yan W, Chen G, Yin H.Cytokine. 2008 Oct;44(1):135-40. doi: 10.1016/j.cyto.2008.07.005. Epub 2008 Aug 21.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: ELISA, TUNEL staining, Grip test, rt-PCR
Citation: Jin W, Wang H, Yan W, Zhu L, Hu Z, Ding Y, Tang K.J Neurotrauma. 2009 Jan;26(1):131-9. doi: 10.1089/neu.2008.0655.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Swiss
Assessments: Immunohistochemistry (IHC), Brain lesion volume
Citation: Homsi S, Piaggio T, Croci N, Noble F, Plotkine M, Marchand-Leroux C, Jafarian-Tehrani M.J Neurotrauma. 2010 May;27(5):911-21. doi: 10.1089/neu.2009.1223.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: open field test, CORT level, Novel object recognition test, foot fault test, Immunofluorescence, NeuN staining, Cresyl violet staining
Citation: Baratz R, Tweedie D, Wang JY, Rubovitch V, Luo W, Hoffer BJ, Greig NH, Pick CG. Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in miceJ Neuroinflammation. 2015 Mar 7;12:45. doi: 10.1186\/s12974-015-0237-4. PMC4352276
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: open field test, CORT level, Novel object recognition test, foot fault test, Immunofluorescence, NeuN staining, Cresyl violet staining
Citation: Baratz-Goldstein R, Toussia-Cohen S, Elpaz A, Rubovitch V, Pick CG. Immediate and delayed hyperbaric oxygen therapy as a neuroprotective treatment for traumatic brain injury in miceMol Cell Neurosci. 2017 Sep;83:74-82. doi: 10.1016\/j.mcn.2017.06.004. Epub 2017 Jul 8.
TBI Model Type: Other
Organism Species: mouse
Organism Strain: C57BL/6N
Assessments: Autoradiography, Immunohistochemistry (IHC), Neurological Severity Score (NSS), hematoxylin and eosin, μPET
Citation: Israel I, Ohsiek A, Al-Momani E, Albert-Weissenberger C, Stetter C, Mencl S, Buck AK, Kleinschnitz C, Samnick S, Sirén AL. Combined [(18)F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in miceJ Neuroinflammation. 2016 Jun 7;13(1):140. doi: 10.1186\/s12974-016-0604-9. PMC4897946
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Enzyme-linked immunosorbent assay (ELISA), Evans blue dye extravasation, Functional Magnetic resonance imaging (MRI), Immunofluorescence, Western blot, Brain water content, Neurological Severity Score (NSS), wire grip test, motion test
Citation: Yang Q, Zhang S, Xu Z, Liu L, Fan S, Wu S, Ma C. The Effectiveness of Trigeminal Nerve Stimulation on Traumatic Brain InjuryNeuromodulation. 2022 Jan 20:S1094-7159(21)06389-3. doi: 10.1016\/j.neurom.2021.10.014. Online ahead of print.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Hippocampal histology, neuron-specific enolase
Citation: Wallen TE, Singer KE, Baucom MR, England LG, Schuster RM, Pritts TA, Goodman MD. Effects of antifibrinolytics on systemic and cerebral inflammation after traumatic brain injuryJ Trauma Acute Care Surg. 2022 Mar 22. doi: 10.1097\/TA.0000000000003607. Online ahead of print.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunohistochemistry (IHC), Nissl Staining, Western blot, Grip test, spectrophotometer
Citation: Zhai X, Ding Y, Wang Q, Zhang H, Li F. Rutin Acid Ameliorates Neural Apoptosis Induced by Traumatic Brain Injury via Mitochondrial Pathways in MiceNeuroimmunomodulation. 2016;23(3):179-187. doi: 10.1159\/000448716. Epub 2016 Sep 20.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Evans blue extravasation, Neurological Severity Score (NSS), Novel object recognition, Rotarod test, TUNEL staining, Western blot, lactate dehydrogenase release
Citation: Wang P, Pan B, Tian J, Yang L, Chen Z, Yang L, Fan Z. Ac-FLTD-CMK inhibits pyroptosis and exerts neuroprotective effect in a mice model of traumatic brain injuryNeuroreport. 2021 Feb 3;32(3):188-197. doi: 10.1097\/WNR.0000000000001580.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Impactor tip motion
Citation: Kim Y, Fu AH, Tucker LB, Liu J, McCabe JT. Characterization of controlled cortical impact devices by high-speed image analysisJ Neurosci Res. 2018 Apr;96(4):501-511. doi: 10.1002\/jnr.24099. Epub 2017 Jul 4.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: CF-1
Assessments: Western blot
Citation: Thompson SN, Gibson TR, Thompson BM, Deng Y, Hall ED. Relationship of calpain-mediated proteolysis to the expression of axonal and synaptic plasticity markers following traumatic brain injury in miceExp Neurol. 2006 Sep;201(1):253-65. doi: 10.1016\/j.expneurol.2006.04.013. Epub 2006 Jun 30.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Histology
Citation: Mirzayan MJ, Probst C, Samii M, Krettek C, Gharabaghi A, Pape HC, van Griensven M, Samii A. Histopathological features of the brain, liver, kidney and spleen following an innovative polytrauma model of the mouseExp Toxicol Pathol. 2012 Mar;64(3):133-9. doi: 10.1016\/j.etp.2010.07.007. Epub 2010 Aug 4.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Hematoxylin and Eosin, Morris Water Maze (MWM), Brain water content, Immunohistochemistry (IHC), seizure activity, wire-grip test
Citation: Dapul HR, Park J, Zhang J, Lee C, DanEshmand A, Lok J, Ayata C, Gray T, Scalzo A, Qiu J, Lo EH, Whalen MJ. Concussive injury before or after controlled cortical impact exacerbates histopathology and functional outcome in a mixed traumatic brain injury model in miceJ Neurotrauma. 2013 Mar 1;30(5):382-91. doi: 10.1089\/neu.2012.2536. Epub 2013 Feb 20. PMC3593692
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Barnes Maze test, Basal ROS production, Enzyme-linked immunosorbent assay (ELISA), Fluoro-Jade C staining (FJC), GSH/GSSG activity assay, Hypoxyprobe staining, Neurological Severity Score, NADPH oxidase activity, Novel object recognition test, Western blot, cell viability analysis, Immunocytochemistry, memory recall test
Citation: Ho MH, Yen CH, Hsieh TH, Kao TJ, Chiu JY, Chiang YH, Hoffer BJ, Chang WC, Chou SY. CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injuryRedox Biol. 2021 Oct;46:102067. doi: 10.1016\/j.redox.2021.102067. Epub 2021 Jul 17. PMC8327355
