On page 5 showing 81 ~ 100 out of 226 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: ELISA, Neurological Severity Score, TUNEL histochemistry, immunohistochemistry, real-time RT-PCR
Citation: Leinhase I, Rozanski M, Harhausen D, Thurman JM, Schmidt OI, Hossini AM, Taha ME, Rittirsch D, Ward PA, Holers VM, Ertel W, Stahel PF.Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in miceJ Neuroinflammation. 2007 May 2;4:13. doi: 10.1186/1742-2094-4-13.PMC186780810.1186/1742-2094-4-13
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: TTC staining method, Current responses, Enzyme-linked immunosorbent assay, Nissl staining, brain water content, immunofluorescent staining, neurological severity score, wet and dry weight method
Citation: Zhai PP, Xu LH, Yang JJ, Jiang ZL, Zhao GW, Sun L, Wang GH, Li X.Reduction of inflammatory responses by L-serine treatment leads to neuroprotection in mice after traumatic brain injury.Neuropharmacology. 2015 Aug;95:1-11. doi: 10.1016/j.neuropharm.2015.02.026. Epub 2015 Mar 5.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Flow Cytometry, Immunohistochemistry, hematoxylin and eosin
Citation: Lee J, Costantini TW, D'Mello R, Eliceiri BP, Coimbra R, Bansal V.Altering leukocyte recruitment following traumatic brain injury with ghrelin therapy.J Trauma Acute Care Surg. 2014 Nov;77(5):709-715. doi: 10.1097/TA.0000000000000445.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Western blotting, immunofluorescence, length of neurites
Citation: Surgucheva I, He S, Rich MC, Sharma R, Ninkina NN, Stahel PF, Surguchov A.Role of synucleins in traumatic brain injury — an experimental in vitro and in vivo study in mice.Mol Cell Neurosci. 2014 Nov;63:114-23. doi: 10.1016/j.mcn.2014.10.005.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: CF-1
Assessments: volume of spared tissue, silver histochemical technique
Citation: Hall ED, Gibson TR, Pavel KM.Lack of a gender difference in post-traumatic neurodegeneration in the mouse controlled cortical impact injury modelJ Neurotrauma. 2005 Jun;22(6):669-79. doi: 10.1089/neu.2005.22.669.10.1089/neu.2005.22.669
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Evans Blue dye, Immunocytochemistry, Lesion volumes, flow cytometry, neurological severity score, real-time PCR, terminal deoxynucleotidyl transferase dUTP nick-end labeling, wet weight-dry weight
Citation: Mencl S, Hennig N, Hopp S, Schuhmann MK, Albert-Weissenberger C, Sirén AL, Kleinschnitz C.FTY720 does not protect from traumatic brain injury in mice despite reducing posttraumatic inflammation.J Neuroimmunol. 2014 Sep 15;274(1-2):125-31. doi: 10.1016/j.jneuroim.2014.07.010. Epub 2014 Jul 22.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Flow Cytometry, Luminex Assays
Citation: Schwulst SJ, Trahanas DM, Saber R, Perlman H.Traumatic brain injury-induced alterations in peripheral immunityJ Trauma Acute Care Surg. 2013 Nov;75(5):780-8. doi: 10.1097/TA.0b013e318299616a.PMC380906010.1097/TA.0b013e318299616a
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Elevated Plus maze test, Novel Object Recognition task, Y maze test
Citation: Schreiber S, Lin R, Haim L, Baratz-Goldstien R, Rubovitch V, Vaisman N, Pick CG.Enriched environment improves the cognitive effects from traumatic brain injury in mice.Behav Brain Res. 2014 Sep 1;271:59-64. doi: 10.1016/j.bbr.2014.05.060. Epub 2014 Jun 4.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: CD1
Assessments: Histological Observation, reverse transcriptase-polymerase chain reaction assay, western blotting technique
Citation: Zhang M, Shan H, Wang T, Liu W, Wang Y, Wang L, Zhang L, Chang P, Dong W, Chen X, Tao L.Dynamic change of hydrogen sulfide after traumatic brain injury and its effect in miceNeurochem Res. 2013 Apr;38(4):714-25. doi: 10.1007/s11064-013-0969-4. Epub 2013 Jan 17.10.1007/s11064-013-0969-4
TBI Model Type: Weight-drop model
Organism Species: mouse
Assessments: Evans Blue Dye Extravasation, Gross vestibulomotor function, Necrotic Cavity Volume, Water Content, beam balance, beam walk
Citation: Mikawa S, Kinouchi H, Kamii H, Gobbel GT, Chen SF, Carlson E, Epstein CJ, Chan PH.Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc-superoxide dismutase transgenic miceJ Neurosurg. 1996 Nov;85(5):885-91. doi: 10.3171/jns.1996.85.5.0885.10.3171/jns.1996.85.5.0885
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Evans blue (EB) extravasation, TUNEL assay, Western blot
Citation: Lu XY, Wang HD, Xu JG, Ding K, Li T.NADPH oxidase inhibition improves neurological outcome in experimental traumatic brain injury.Neurochem Int. 2014 Apr;69:14-9. doi: 10.1016/j.neuint.2014.02.006. Epub 2014 Feb 28.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/J6
Assessments: flow cytometry
Citation: Probst C, Mirzayan MJ, Mommsen P, Zeckey C, Tegeder T, Geerken L, Maegele M, Samii A, van Griensven M.Systemic inflammatory effects of traumatic brain injury, femur fracture, and shock: an experimental murine polytrauma modelMediators Inflamm. 2012;2012:136020. doi: 10.1155/2012/136020. Epub 2012 Mar 4.PMC331699810.1155/2012/136020
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Western blot
Citation: Lu XY, Wang HD, Xu JG, Ding K, Li T.Pretreatment with tert-butylhydroquinone attenuates cerebral oxidative stress in mice after traumatic brain injury.J Surg Res. 2014 May 1;188(1):206-12. doi: 10.1016/j.jss.2013.11.1106. Epub 2013 Dec 1.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Beam balancing, Beam walk, Immunhistochemical, Round stick balancing, Startle reflex, neurological severity score
Citation: Albert-Weißenberger C, Várrallyay C, Raslan F, Kleinschnitz C, Sirén AL.An experimental protocol for mimicking pathomechanisms of traumatic brain injury in miceExp Transl Stroke Med. 2012 Feb 2;4:1. doi: 10.1186/2040-7378-4-1.PMC330549210.1186/2040-7378-4-1
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: BALB/c
Assessments: Morphometry, Neurobehavioral Evaluation
Citation: Wu Q, Xuan W, Ando T, Xu T, Huang L, Huang YY, Dai T, Dhital S, Sharma SK, Whalen MJ, Hamblin MR.Low-level laser therapy for closed-head traumatic brain injury in mice: effect of different wavelengthsLasers Surg Med. 2012 Mar;44(3):218-26. doi: 10.1002/lsm.22003. Epub 2012 Jan 24.PMC339720310.1002/lsm.22003
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Motor evaluation, Enzyme-linked immunosorbent assay (ELISA)
Citation: Yang SH, Gangidine M, Pritts TA, Goodman MD, Lentsch AB.Interleukin 6 mediates neuroinflammation and motor coordination deficits after mild traumatic brain injury and brief hypoxia in mice.Shock. 2013 Dec;40(6):471-5. doi: 10.1097/SHK.0000000000000037.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Microdialysis in vivo, open field test, Resident-Intruder, Rotarod test, Tactile Allodynia, Tail Suspension Test, Three Chambers Sociability
Citation: Belardo C, Iannotta M, Boccella S, Rubino RC, Ricciardi F, Infantino R, Pieretti G, Stella L, Paino S, Marabese I, Maisto R, Luongo L, Maione S, Guida F. Oral Cannabidiol Prevents Allodynia and Neurological Dysfunctions in a Mouse Model of Mild Traumatic Brain InjuryFront Pharmacol. 2019 Apr 16;10:352. doi: 10.3389\/fphar.2019.00352. eCollection 2019. PMC6476923
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57/BL6
Assessments: (wet–dry)/wet brain weight method, Blood–Brain Barrier Permeability, Chronic Brain Tissue Loss, Histochemical, Injured Cell Counts, Morris Water Maze, Nuclear Factor-κB Transcription Factor Assay, Quantitative Real-Time Reverse Transcriptase PCR, Tumor Necrosis Factor-α Enzyme-Linked Immunosorbent Assay, Wire-Grip Test, immunohistochemical, light microscopy
Citation: Khuman J, Meehan WP 3rd, Zhu X, Qiu J, Hoffmann U, Zhang J, Giovannone E, Lo EH, Whalen MJ.Tumor necrosis factor alpha and Fas receptor contribute to cognitive deficits independent of cell death after concussive traumatic brain injury in miceJ Cereb Blood Flow Metab. 2011 Feb;31(2):778-89. doi: 10.1038/jcbfm.2010.172. Epub 2010 Oct 13.PMC304953210.1038/jcbfm.2010.172
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Balb/c
Assessments: Histological, Immunoblotting, In vivo intestinal permeability assay
Citation: Bansal V, Ryu SY, Blow C, Costantini T, Loomis W, Eliceiri B, Baird A, Wolf P, Coimbra R.The hormone ghrelin prevents traumatic brain injury induced intestinal dysfunctionJ Neurotrauma. 2010 Dec;27(12):2255-60. doi: 10.1089/neu.2010.1372. Epub 2010 Nov 2.PMC330424910.1089/neu.2010.1372
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Morris water maze (MWM), Hidden Platform, Novel object recognition (NOR), Y-Maze Test
Citation: Eakin K, Baratz-Goldstein R, Pick CG, Zindel O, Balaban CD, Hoffer ME, Lockwood M, Miller J, Hoffer BJ.Efficacy of N-acetyl cysteine in traumatic brain injury.PLoS One. 2014 Apr 16;9(4):e90617. doi: 10.1371/journal.pone.0090617. eCollection 2014.
