On page 4 showing 61 ~ 80 out of 249 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: TUNEL staining, Brain water content, Fluoro-Jade B staining (FJB), Immunofluorescence, RT- PCR, Western blot, modified Garcia score
Citation: Rui Q, Ni H, Gao F, Dang B, Li D, Gao R, Chen G. LRRK2 Contributes to Secondary Brain Injury Through a p38\/Drosha Signaling Pathway After Traumatic Brain Injury in RatsFront Cell Neurosci. 2018 Mar 1;12:51. doi: 10.3389\/fncel.2018.00051. eCollection 2018. PMC5837969
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Adhesion-Removal Test, beam walk, Immunohistochemistry (IHC), modified Neurological Severity Score (mNSS), Novel object recognition test, open field test
Citation: Kuo CW, Chang MY, Liu HH, He XK, Chan SY, Huang YZ, Peng CW, Chang PK, Pan CY, Hsieh TH. Cortical Electrical Stimulation Ameliorates Traumatic Brain Injury-Induced Sensorimotor and Cognitive Deficits in RatsFront Neural Circuits. 2021 Jun 14;15:693073. doi: 10.3389\/fncir.2021.693073. eCollection 2021. PMC8236591
TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: CNN-based segmentation maps, Loss Function, Magnetic resonance imaging (MRI), hippocampus segmentation task, skull-stripping task
Citation: De Feo R, Hämäläinen E, Manninen E, Immonen R, Valverde JM, Ndode-Ekane XE, Gröhn O, Pitkänen A, Tohka J. Convolutional Neural Networks Enable Robust Automatic Segmentation of the Rat Hippocampus in MRI After Traumatic Brain InjuryFront Neurol. 2022 Feb 17;13:820267. doi: 10.3389\/fneur.2022.820267. eCollection 2022. PMC8891699
TBI Model Type: Blast model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Western blot
Citation: Arun P, Oguntayo S, Albert SV, Gist I, Wang Y, Nambiar MP, Long JB. Acute decrease in alkaline phosphatase after brain injury: A potential mechanism for tauopathyNeurosci Lett. 2015 Nov 16;609:152-8. doi: 10.1016\/j.neulet.2015.10.036. Epub 2015 Oct 19.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: 1H-MRS, Beam walk test, LC Model, Magnetic resonance imaging (MRI), Novel object recognition test, Open field exploratory
Citation: Singh K, Trivedi R, Haridas S, Manda K, Khushu S. Study of neurometabolic and behavioral alterations in rodent model of mild traumatic brain injury: a pilot studyNMR Biomed. 2016 Dec;29(12):1748-1758. doi: 10.1002\/nbm.3627. Epub 2016 Oct 25.
TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Wistar
Assessments: Cell Morphology
Citation: Gupta A, Dovek L, Proddutur A, Elgammal FS, Santhakumar V. Long-Term Effects of Moderate Concussive Brain Injury During Adolescence on Synaptic and Tonic GABA Currents in Dentate Granule Cells and Semilunar Granule CellsFront Neurosci. 2022 Mar 14;16:800733. doi: 10.3389\/fnins.2022.800733. eCollection 2022. PMC8964009
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Lewis
Assessments: Immunohistochemistry (IHC)
Citation: Xu K, Yang Z, Shi R, Luo C, Zhang Z. Expression of aryl hydrocarbon receptor in rat brain lesions following traumatic brain injuryDiagn Pathol. 2016 Aug 9;11(1):72. doi: 10.1186\/s13000-016-0522-2. PMC4977631
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: RT-PCR, TUNEL staining
Citation: Park CO, Yi HG. Apoptotic change and NOS activity in the experimental animal diffuse axonal injury modelYonsei Med J. 2001 Oct;42(5):518-26. doi: 10.3349\/ymj.2001.42.5.518.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: High resolution respirometry, Mitochondrial respiration assay, object recognition test, open field test, Rotarod test
Citation: Courtes AA, Gonçalves DF, Hartmann DD, da Rosa PC, Cassol G, Royes LFF, de Carvalho NR, Soares FAA. Guanosine protects against behavioural and mitochondrial bioenergetic alterations after mild traumatic brain injuryBrain Res Bull. 2020 Oct;163:31-39. doi: 10.1016\/j.brainresbull.2020.07.003. Epub 2020 Jul 15.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Error ladder test, Histology, Novel objective recognition (NOR) test, Sticky tape test, Western blotting, immunohistochemistry, novel object recognition
Citation: Zakarya R, Sapkota A, Chan YL, Shah J, Saad S, Bottle SE, Oliver BG, Gorrie CA, Chen H.Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injuryNitric Oxide. 2020 Apr 1;97:57-65. doi: 10.1016/j.niox.2020.02.001. Epub 2020 Feb 13.10.1016/j.niox.2020.02.001
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague–Dawley
Citation: Blaya M, Truettner J, Zhao W, Bramlett H, Dietrich WD.Mild Hyperthermia Aggravates Glucose Metabolic Consequences in Repetitive ConcussionInt J Mol Sci. 2020 Jan 17;21(2):609. doi: 10.3390/ijms21020609.PMC701383810.3390/ijms21020609
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Long Evans
Assessments: ELISA test, Immunohistochemistry, Morris water maze test, Novel object recognition test, open field test
Citation: Tadepalli SA, Bali ZK, Bruszt N, Nagy LV, Amrein K, Fazekas B, Büki A, Czeiter E, Hernádi I.Long-term cognitive impairment without diffuse axonal injury following repetitive mild traumatic brain injury in ratsBehav Brain Res. 2020 Jan 27;378:112268. doi: 10.1016/j.bbr.2019.112268. Epub 2019 Sep 30.10.1016/j.bbr.2019.112268
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague‐Dawley
Assessments: Brain water content, Enzyme‐linked immunosorbent assay, Immunohistochemical, Real‐time quantitative polymerase chain reaction, TUNEL, Terminal deoxynucleotidyl transferase‐mediated dUTP nick‐end labeling, Western blot, neurological severity score
Citation: Li F, Wang X, Zhang Z, Zhang X, Gao P.Dexmedetomidine Attenuates Neuroinflammatory-Induced Apoptosis after Traumatic Brain Injury via Nrf2 signaling pathwayAnn Clin Transl Neurol. 2019 Sep;6(9):1825-1835. doi: 10.1002/acn3.50878. Epub 2019 Sep 3.PMC676450110.1002/acn3.50878
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: magnetic resonance imaging
Citation: Braeckman K, Descamps B, Vanhove C.Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain InjuryJ Vis Exp. 2019 Aug 14;(150). doi: 10.3791/60012.10.3791/60012
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Evans blue, FABP7, Neurological score, brain edema, immunofluorescence staining, real-time PCR, western blotting
Citation: Rui Q, Ni H, Lin X, Zhu X, Li D, Liu H, Chen G.Astrocyte-derived fatty acid-binding protein 7 protects blood-brain barrier integrity through a caveolin-1/MMP signaling pathway following traumatic brain injuryExp Neurol. 2019 Dec;322:113044. doi: 10.1016/j.expneurol.2019.113044. Epub 2019 Aug 24.10.1016/j.expneurol.2019.113044
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Dark neuron, Terminal deoxynucleotidyl transferase-mediated biotinylated dUTP nick-end labeling, Western blotting, modified Neurological Severity Score, western blot
Citation: Ghadiri T, Vakilzadeh G, Hajali V, Khodagholi F.Progesterone modulates post-traumatic epileptogenesis through regulation of BDNF-TrkB signaling and cell survival-related pathways in the rat hippocampusNeurosci Lett. 2019 Sep 14;709:134384. doi: 10.1016/j.neulet.2019.134384. Epub 2019 Jul 17.10.1016/j.neulet.2019.134384
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain edema, Cell Death Assays, Enzyme-Linked Immunosorbent Assay, Evans Blue Dye Extravasation, Immunofluorescence Staining, Neurological, Real-Time PCR, Western Blotting, cresyl violet
Citation: Ni H, Rui Q, Lin X, Li D, Liu H, Chen G.2-BFI Provides Neuroprotection Against Inflammation and Necroptosis in a Rat Model of Traumatic Brain InjuryFront Neurosci. 2019 Jun 26;13:674. doi: 10.3389/fnins.2019.00674. eCollection 2019.PMC660678410.3389/fnins.2019.00674
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Western blot, immunohistochemical staining, neurological severity score, real-time quantitative polymerase chain reaction, terminal deoxynucleotidyl transferase dUTP nick end labeling assay
Citation: Li F, Wang X, Zhang Z, Gao P, Zhang X.Breviscapine provides a neuroprotective effect after traumatic brain injury by modulating the Nrf2 signaling pathwayJ Cell Biochem. 2019 Sep;120(9):14899-14907. doi: 10.1002/jcb.28751. Epub 2019 May 1.10.1002/jcb.28751
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beta-hydroxybutyrate level, Brainwater content, Cytochrome c assay, TUNEL staining, glucose measurement
Citation: Hu ZG, Wang HD, Jin W, Yin HX. Ketogenic diet reduces cytochrome c release and cellular apoptosis following traumatic brain injury in juvenile ratsAnn Clin Lab Sci. 2009 Winter;39(1):76-83.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay, Immunofluorescence staining, Lesion volume, Survival assay, Western blot, modified neurological severity score, scanning electron microscope
Citation: Hu J, Chen L, Huang X, Wu K, Ding S, Wang W, Wang B, Smith C, Ren C, Ni H, ZhuGe Q, Yang J.Calpain inhibitor MDL28170 improves the transplantation-mediated therapeutic effect of bone marrow-derived mesenchymal stem cells following traumatic brain injuryStem Cell Res Ther. 2019 Mar 15;10(1):96. doi: 10.1186/s13287-019-1210-4.PMC642077510.1186/s13287-019-1210-4
