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On page 3 showing 41 ~ 60 out of 498 results
Snippet Table

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Hematoxylin and Eosin, Neurological Severity Score (NSS), Nissl staining, Timm stain
Citation: Ezaki J, Shimada R, Shibuya M, Kibayashi K. Hippocampal neuronal degeneration in the traumatic brain injury mouse: non-trivial effect of scalp incisionNeurol Res. 2016 Nov;38(11):994-1002. doi: 10.1080\/01616412.2016.1228746. Epub 2016 Sep 10.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Prussian blue staining, Cerebral blood flow, COIS imaging, Immunohistochemistry (IHC), seizure activity
Citation: Bouley J, Chung DY, Ayata C, Brown RH Jr, Henninger N. Cortical Spreading Depression Denotes Concussion InjuryJ Neurotrauma. 2019 Apr 1;36(7):1008-1017. doi: 10.1089\/neu.2018.5844. Epub 2018 Aug 24. PMC6444888

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57Bl/6
Assessments: Brain water content, Enzyme-Linked Immunosorbent Assay (Enzyme-linked immunosorbent assay), Evans Blue Extravasation, Magnetic resonance imaging (MRI), Western Blot, Y-maze, open-field, rotarod
Citation: Shultz SR, Sun M, Wright DK, Brady RD, Liu S, Beynon S, Schmidt SF, Kaye AH, Hamilton JA, O'Brien TJ, Grills BL, McDonald SJ. Tibial fracture exacerbates traumatic brain injury outcomes and neuroinflammation in a novel mouse model of multitraumaJ Cereb Blood Flow Metab. 2015 Aug;35(8):1339-47. doi: 10.1038\/jcbfm.2015.56. Epub 2015 Apr 8. PMC4528010

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Histology, Morris Water Maze (MWM)
Citation: Smith DH, Soares HD, Pierce JS, Perlman KG, Saatman KE, Meaney DF, Dixon CE, McIntosh TK. A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effectsJ Neurotrauma. 1995 Apr;12(2):169-78. doi: 10.1089\/neu.1995.12.169.

TBI Model Type: Controlled cortical impact model
Organism Species: pig
Organism Strain: Yorkshire
Assessments: Histology
Citation: Sindelar B, Bailes J, Sherman S, Finan J, Stone J, Lee J, Ahmadian S, Zhou Y, Patel V, Smith D. Effect of Internal Jugular Vein Compression on Intracranial Hemorrhage in a Porcine Controlled Cortical Impact ModelJ Neurotrauma. 2017 Apr 15;34(8):1703-1709. doi: 10.1089\/neu.2016.4648. Epub 2016 Dec 16.

TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Western blot
Citation: Griesbach GS, Hovda DA, Gomez-Pinilla F, Sutton RL. Voluntary exercise or amphetamine treatment, but not the combination, increases hippocampal brain-derived neurotrophic factor and synapsin I following cortical contusion injury in ratsNeuroscience. 2008 Jun 23;154(2):530-40. doi: 10.1016\/j.neuroscience.2008.04.003. Epub 2008 Apr 9. PMC2441485

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: RT-PCR
Citation: Sandhir R, Berman NE. Age-dependent response of CCAAT\/enhancer binding proteins following traumatic brain injury in miceNeurochem Int. 2010 Jan;56(1):188-93. doi: 10.1016\/j.neuint.2009.10.002. Epub 2009 Oct 13. PMC2815015

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: flow cytometry, ATP detection, Bradford method, Hematoxylin and eosin, Immunofluorescence, L-lactate assay kit, Morris Water Maze (MWM)
Citation: Dong T, Zhang Q, Hamblin MR, Wu MX. Low-level light in combination with metabolic modulators for effective therapy of injured brainJ Cereb Blood Flow Metab. 2015 Sep;35(9):1435-44. doi: 10.1038\/jcbfm.2015.87. Epub 2015 May 13. PMC4640344

TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: L/D emergence task, Enzyme-linked immunosorbent assay (ELISA), Barnes Maze test test, Contextual fear memory testing, Elevated zero maze, Fear conditioning, Immunohistochemistry (IHC), Light dark escape, Locomotor activity, Novel object localization test, Novel object recognition test, Oligomeric Aβ42 dot blot analysis, Social interaction, Sound-attenuated isolation, Behavioral Testing, Thioflavin S staining, social preference test
Citation: Perez Garcia G, De Gasperi R, Tschiffely AE, Gama Sosa MA, Abutarboush R, Kawoos U, Statz JK, Ciarlone S, Reed E, Jeyarajah T, Perez GM, Otero-Pagan A, Pryor D, Hof PR, Cook DG, Gandy S, Elder GA, Ahlers ST. Repetitive Low-Level Blast Exposure Improves Behavioral Deficits and Chronically Lowers Aβ42 in an Alzheimer Disease Transgenic Mouse ModelJ Neurotrauma. 2021 Nov 15;38(22):3146-3173. doi: 10.1089\/neu.2021.0184. Epub 2021 Sep 15. PMC8820291

TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Image analysis, Magnetic resonance imaging (MRI)
Citation: Zhang H, Wang W, Jiang S, Zhang Y, Heo HY, Wang X, Peng Y, Wang J, Zhou J. Amide proton transfer-weighted MRI detection of traumatic brain injury in ratsJ Cereb Blood Flow Metab. 2017 Oct;37(10):3422-3432. doi: 10.1177\/0271678X17690165. Epub 2017 Jan 27. PMC5624391

TBI Model Type: Blast model
Organism Species: rat
Organism Strain: Long-Evans
Assessments: Contextual fear memory testing, Novel object recognition test, Sound-attenuated isolation, elevated zero maze apparatus, Immunohistochemistry (IHC), light/dark emergence task
Citation: Perez Garcia G, Perez GM, Otero-Pagan A, Abutarboush R, Kawoos U, De Gasperi R, Gama Sosa MA, Pryor D, Hof PR, Cook DG, Gandy S, Ahlers ST, Elder GA. Transcranial Laser Therapy Does Not Improve Cognitive and Post-Traumatic Stress Disorder-Related Behavioral Traits in Rats Exposed to Repetitive Low-Level Blast InjuryNeurotrauma Rep. 2021 Dec 2;2(1):548-563. doi: 10.1089\/neur.2021.0005. eCollection 2021. PMC8655798

TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Wistar
Assessments: Diffusion Tensor Imaging scan, Neurological Severity Score (NSS)
Citation: Nakuci J, McGuire M, Schweser F, Poulsen D, Muldoon SF. Differential Patterns of Change in Brain Connectivity Resulting from Severe Traumatic Brain InjuryBrain Connect. 2022 May 5. doi: 10.1089\/brain.2021.0168. Online ahead of print.

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Elevated plus maze, Forced swim test, Horizontal ladder beam, Immunohistochemistry (IHC), Morris Water Maze (MWM), Rotarod, Tail suspension test, Western Blots, optical fractionator probe
Citation: Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ. Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral DeficitsASN Neuro. 2018 Jan-Dec;10:1759091418781921. doi: 10.1177\/1759091418781921. PMC6050992

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Biochemical Assay, Brain water content, Hematoxylin and Eosin, Immunohistochemistry (IHC), modified Neurological Severity Score (mNSS), qRT-PCR, TUNEL staining, Western blot
Citation: Tang Y, Dong X, Chen G, Ye W, Kang J, Tang Y, Feng Z. Vagus Nerve Stimulation Attenuates Early Traumatic Brain Injury by Regulating the NF-κB\/NLRP3 Signaling PathwayNeurorehabil Neural Repair. 2020 Sep;34(9):831-843. doi: 10.1177\/1545968320948065. Epub 2020 Aug 10.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Body temperature, Blood gas analysis, blood pH, laser doppler flowmetry
Citation: Roof RL, Hall ED. Estrogen-related gender difference in survival rate and cortical blood flow after impact-acceleration head injury in ratsJ Neurotrauma. 2000 Dec;17(12):1155-69. doi: 10.1089\/neu.2000.17.1155.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Blood–brain barrier permeability, glutathione levels, Histology, malondialdehyde (MDA)
Citation: Özevren H, Deveci E, Tuncer MC. Histopathological changes in the choroid plexus after traumatic brain injury in the rats: a histologic and immunohistochemical studyFolia Morphol (Warsz). 2018;77(4):642-648. doi: 10.5603\/FM.a2018.0029. Epub 2018 Mar 23.

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6-SJLF1
Assessments: Conditioned fear testing, Morris Water Maze (MWM), Rotorod test, Histology, shock sensitivity testing
Citation: Brody DL, Mac Donald C, Kessens CC, Yuede C, Parsadanian M, Spinner M, Kim E, Schwetye KE, Holtzman DM, Bayly PV. Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injuryJ Neurotrauma. 2007 Apr;24(4):657-73. doi: 10.1089\/neu.2006.0011. PMC2435168

TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: up-down method, von Frey filament, DNIC assessment, Immunohistochemistry (IHC)
Citation: Irvine KA, Peters CM, Vazey EM, Ferguson AR, Clark D. DREADD-mediated activation of the locus coeruleus restores descending nociceptive inhibition after traumatic brain injury in ratsJ Neurotrauma. 2022 Apr 12. doi: 10.1089\/neu.2021.0485. Online ahead of print.

TBI Model Type: Controlled cortical impact model
Organism Species: pig
Organism Strain: No strain reported
Assessments: Histology, Immunohistochemistry (IHC), microdialysis
Citation: Kilbaugh TJ, Bhandare S, Lorom DH, Saraswati M, Robertson CL, Margulies SS. Cyclosporin A preserves mitochondrial function after traumatic brain injury in the immature rat and pigletJ Neurotrauma. 2011 May;28(5):763-74. doi: 10.1089\/neu.2010.1635. Epub 2011 Apr 12. PMC3125546

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Amyloid precursor protein, Cortical contusion volume, Immunoglobulin, Immunohistochemistry (IHC), Morris Water Maze (MWM), Neurological Severity Score (NSS), Neuroscore, Regional hippocampal neurodegeneration
Citation: Pleasant JM, Carlson SW, Mao H, Scheff SW, Yang KH, Saatman KE. Rate of neurodegeneration in the mouse controlled cortical impact model is influenced by impactor tip shape: implications for mechanistic and therapeutic studiesJ Neurotrauma. 2011 Nov;28(11):2245-62. doi: 10.1089\/neu.2010.1499. Epub 2011 Apr 21. PMC3218388

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The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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