On page 3 showing 41 ~ 60 out of 249 results
TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Magnetic resonance imaging (MRI)
Citation: De Feo R, Manninen E, Chary K, Hämäläinen E, Immonen R, Andrade P, Ndode-Ekane XE, Gröhn O, Pitkänen A, Tohka J. Hippocampal position and orientation as prognostic biomarkers for posttraumatic epileptogenesis: An experimental study in a rat lateral fluid percussion modelEpilepsia. 2022 Apr 22. doi: 10.1111\/epi.17264. Online ahead of print.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: FTIR Imaging studies, Hematoxylin and Eosin
Citation: Ustaoglu SG, Ali MHM, Rakib F, Blezer ELA, Van Heijningen CL, Dijkhuizen RM, Severcan F. Biomolecular changes and subsequent time-dependent recovery in hippocampal tissue after experimental mild traumatic brain injurySci Rep. 2021 Jun 14;11(1):12468. doi: 10.1038\/s41598-021-92015-3. PMC8203626
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Brain water content, Western blot
Citation: Lu KT, Huang TC, Tsai YH, Yang YL. Transient receptor potential vanilloid type 4 channels mediate Na-K-Cl-co-transporter-induced brain edema after traumatic brain injuryJ Neurochem. 2017 Mar;140(5):718-727. doi: 10.1111\/jnc.13920.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Evans blue dye, Immunohistochemistry (IHC), SOD activity, GSH-PX activity, MDA activity, qRT-PCR, Western blot, Brain water content
Citation: Zhang B, Wang B, Cao S, Wang Y. Epigallocatechin-3-Gallate (EGCG) Attenuates Traumatic Brain Injury by Inhibition of Edema Formation and Oxidative StressKorean J Physiol Pharmacol. 2015 Nov;19(6):491-7. doi: 10.4196\/kjpp.2015.19.6.491. Epub 2015 Oct 16. PMC4637351
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: strip chart, blood pH, blood pO2, blood pCO2, blood HCO3
Citation: Marmarou A, Foda MA, van den Brink W, Campbell J, Kita H, Demetriadou K. A new model of diffuse brain injury in rats. Part I: Pathophysiology and biomechanicsJ Neurosurg. 1994 Feb;80(2):291-300. doi: 10.3171\/jns.1994.80.2.0291.
TBI Model Type: Other
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, microsensor probe
Citation: Engelborghs K, Verlooy J, Van Reempts J, Van Deuren B, Van de Ven M, Borgers M. Temporal changes in intracranial pressure in a modified experimental model of closed head injuryJ Neurosurg. 1998 Nov;89(5):796-806. doi: 10.3171\/jns.1998.89.5.0796.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: CM-DiI dye, DiR dye, Enzyme-Linked Immunosorbent Assay (ELISA), Immunohistochemistry (IHC), TUNEL staining, Western blot, qRT-PCR
Citation: Chen Y, Li J, Ma B, Li N, Wang S, Sun Z, Xue C, Han Q, Wei J, Zhao RC. MSC-derived exosomes promote recovery from traumatic brain injury via microglia\/macrophages in ratAging (Albany NY). 2020 Sep 23;12(18):18274-18296. doi: 10.18632\/aging.103692. Online ahead of print. PMC7585083
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: wet weight-dry weight, Enzyme-linked immunosorbent assay (ELISA), Immunohistochemistry (IHC)
Citation: Weiss E, Dhir T, Collett A, Reola M, Kaplan M, Minimo C, Omert L, Leung P. Effect of complement C1-esterase inhibitor on brain edema and inflammation after mild traumatic brain injury in an animal modelClin Exp Emerg Med. 2020 Jun;7(2):87-94. doi: 10.15441\/ceem.19.050. Epub 2020 Jun 30. PMC7348678
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: No strain reported
Assessments: immunofluorescence, Western blot
Citation: Cai Z, Zhu W, Zhao H, Yang P, Yang Y, Xu F. Dynamic Expression of Platelet-Derived Growth Factor-D and Phosphorylated Platelet-Derived Growth Factor Receptor-Β after Traumatic Brain Injury in RatsClin Lab. 2020 Nov 1;66(11). doi: 10.7754\/Clin.Lab.2020.200328.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Cytokine Assay, Enzyme-linked immunosorbent assay(ELISA), Immunohistochemistry (IHC), hippocampal neurogenesis, microglia response, radial arm water maze, Rotarod
Citation: Chen MM, Zhao GW, He P, Jiang ZL, Xi X, Xu SH, Ma DM, Wang Y, Li YC, Wang GH. Improvement in the neural stem cell proliferation in rats treated with modified \Shengyu\ decoction may contribute to the neurorestorationJ Ethnopharmacol. 2015 May 13;165:9-19. doi: 10.1016\/j.jep.2015.02.037. Epub 2015 Feb 20.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Brain water content, Hematoxylin and Eosin, qRT-PCR, Western blot, Neurological Severity Score (NSS), TUNEL staining
Citation: Li Z, Wang Y, Zeng G, Zheng X, Wang W, Ling Y, Tang H, Zhang J. Increased miR-155 and heme oxygenase-1 expression is involved in the protective effects of formononetin in traumatic brain injury in ratsAm J Transl Res. 2017 Dec 15;9(12):5653-5661. eCollection 2017. PMC5752915
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Hematoxylin and Eosin, qPCR, Western blot
Citation: Xing P, Ma K, Li L, Wang D, Hu G, Long W. The protection effect and mechanism of hyperbaric oxygen therapy in rat brain with traumatic injuryActa Cir Bras. 2018 Apr;33(4):341-353. doi: 10.1590\/s0102-865020180040000006.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: ATP Assay, Behavioral Testing, Activity score, Brain water content, Fluoro-jade C staining (FJC), Immunofluorescence, Neurological score, RT-PCR, TUNEL staining, Western blot
Citation: Chen C, Lu L, Zhu J, Gu X, Liu B, Li D, Chen G. Miro1 provides neuroprotection via the mitochondrial trafficking pathway in a rat model of traumatic brain injuryBrain Res. 2021 Dec 15;1773:147685. doi: 10.1016\/j.brainres.2021.147685. Epub 2021 Oct 9.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: hindlimb reflexive ability, single probe trial, Cortical lesion volume, Morris Mater Maze (MWM), Beam balance test, Beam walk test, righting reflex, Rotarod test, Cresyl violet staining
Citation: Monaco CM, Mattiola VV, Folweiler KA, Tay JK, Yelleswarapu NK, Curatolo LM, Matter AM, Cheng JP, Kline AE. Environmental enrichment promotes robust functional and histological benefits in female rats after controlled cortical impact injuryExp Neurol. 2013 Sep;247:410-8. doi: 10.1016\/j.expneurol.2013.01.007. Epub 2013 Jan 16. PMC3644389
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: DTI data processing, Histology, Magnetic resonance imaging (MRI), Microscope analysis, Enzyme-linked immunosorbent assay (ELISA)
Citation: Singh K, Trivedi R, Devi MM, Tripathi RP, Khushu S. Longitudinal changes in the DTI measures, anti-GFAP expression and levels of serum inflammatory cytokines following mild traumatic brain injuryExp Neurol. 2016 Jan;275 Pt 3:427-435. doi: 10.1016\/j.expneurol.2015.07.016. Epub 2015 Jul 26.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Han
Assessments: RT-PCR, elevated plus maze, Barnes Maze test, Microarray, Rotarod test, Enzyme-linked immunosorbent assay (ELISA), rotating pole
Citation: Chakraborty N, Hammamieh R, Gautam A, Miller SA, Condlin ML, Jett M, Scrimgeour AG. TBI weight-drop model with variable impact heights differentially perturbs hippocampus-cerebellum specific transcriptomic profileExp Neurol. 2021 Jan;335:113516. doi: 10.1016\/j.expneurol.2020.113516. Epub 2020 Oct 22.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunohistochemistry (IHC), LC-MS/MS analysis, RT-PCR, Western blot
Citation: Wang H, Chen J, Gao C, Chen W, Chen G, Zhang M, Luo C, Wang T, Chen X, Tao L. TMT-based proteomics analysis to screen potential biomarkers of acute-phase TBI in ratsLife Sci. 2021 Jan 1;264:118631. doi: 10.1016\/j.lfs.2020.118631. Epub 2020 Oct 22.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunohistochemistry (IHC), Limb placing test, Performance time rate, RRT, SPRT, limb placing test, Hematoxylin and Eosin
Citation: Yoon YS, Cho KH, Kim ES, Lee MS, Lee KJ. Effect of Epidural Electrical Stimulation and Repetitive Transcranial Magnetic Stimulation in Rats With Diffuse Traumatic Brain InjuryAnn Rehabil Med. 2015 Jun;39(3):416-24. doi: 10.5535\/arm.2015.39.3.416. Epub 2015 Jun 30. PMC4496513
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Immunohistochemistry (IHC), Neurological examination, RRT, SPRT, Single pellet reaching task, Y-maze test
Citation: Yu KP, Yoon YS, Lee JG, Oh JS, Lee JS, Seog T, Lee HY. Effects of Electric Cortical Stimulation (ECS) and Transcranial Direct Current Stimulation (tDCS) on Rats With a Traumatic Brain InjuryAnn Rehabil Med. 2018 Aug;42(4):502-513. doi: 10.5535\/arm.2018.42.4.502. Epub 2018 Aug 31. PMC6129703
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: in-house bred
Assessments: Beam walk test, Elevated plus maze, Forced swim test, Novel context mismatch test, open field test, qRT-PCR
Citation: Mychasiuk R, Hehar H, Candy S, Ma I, Esser MJ. The direction of the acceleration and rotational forces associated with mild traumatic brain injury in rodents effect behavioural and molecular outcomesJ Neurosci Methods. 2016 Jan 15;257:168-78. doi: 10.1016\/j.jneumeth.2015.10.002. Epub 2015 Oct 17.
