On page 3 showing 41 ~ 60 out of 226 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry (IHC), Western blot, spectrophotometer
Citation: Li X, Wang H, Gao Y, Li L, Tang C, Wen G, Yang Y, Zhuang Z, Zhou M, Mao L, Fan Y. Quercetin induces mitochondrial biogenesis in experimental traumatic brain injury via the PGC-1α signaling pathwayAm J Transl Res. 2016 Aug 15;8(8):3558-66. eCollection 2016. PMC5009408
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Cavalieri’s method, Hematoxylin and Eosin, Neurological Severity Score (NSS), ORT, Rotarod test, Western blot, Y Maze
Citation: Ji X, Peng D, Zhang Y, Zhang J, Wang Y, Gao Y, Lu N, Tang P. Astaxanthin improves cognitive performance in mice following mild traumatic brain injuryBrain Res. 2017 Mar 15;1659:88-95. doi: 10.1016\/j.brainres.2016.12.031. Epub 2016 Dec 31.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Swiss Albino
Assessments: Evans blue staining, Immunohistochemistry (IHC), Neurological Severity Score (NSS), open field test, R(−)-apomorphine challenge, Rotarod test, Western blot
Citation: de Oliveira PA, Ben J, Matheus FC, Schwarzbold ML, Moreira ELG, Rial D, Walz R, Prediger RD. Moderate traumatic brain injury increases the vulnerability to neurotoxicity induced by systemic administration of 6-hydroxydopamine in miceBrain Res. 2017 May 15;1663:78-86. doi: 10.1016\/j.brainres.2017.03.002. Epub 2017 Mar 11.
TBI Model Type: Fluid percussion injury model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Agilent 2200 TapeStation assay, DEX, Immunohistochemistry (IHC), LTP assessment, NanoString nCounter analysis, open field test, Paired-pulse ratio, Trace fear conditioning, Y-maze task, electrophysiological assessment
Citation: Tapp ZM, Cornelius S, Oberster A, Kumar JE, Atluri R, Witcher KG, Oliver B, Bray C, Velasquez J, Zhao F, Peng J, Sheridan J, Askwith C, Godbout JP, Kokiko-Cochran ON. Sleep fragmentation engages stress-responsive circuitry, enhances inflammation and compromises hippocampal function following traumatic brain injuryExp Neurol. 2022 Jul;353:114058. doi: 10.1016\/j.expneurol.2022.114058. Epub 2022 Mar 28. PMC9068267
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Enzyme-linked immunosorbent assay (ELISA), Rotational thromboelastometry, Splenic cytology
Citation: Boudreau RM, Johnson M, Veile R, Friend LA, Goetzman H, Pritts TA, Caldwell CC, Makley AT, Goodman MD. Impact of tranexamic acid on coagulation and inflammation in murine models of traumatic brain injury and hemorrhageJ Surg Res. 2017 Jul;215:47-54. doi: 10.1016\/j.jss.2017.03.031. Epub 2017 Apr 1.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6
Assessments: L/D emergence task, Enzyme-linked immunosorbent assay (ELISA), Barnes Maze test test, Contextual fear memory testing, Elevated zero maze, Fear conditioning, Immunohistochemistry (IHC), Light dark escape, Locomotor activity, Novel object localization test, Novel object recognition test, Oligomeric Aβ42 dot blot analysis, Social interaction, Sound-attenuated isolation, Behavioral Testing, Thioflavin S staining, social preference test
Citation: Lesniak A, Pick CG, Misicka A, Lipkowski AW, Sacharczuk M. Biphalin protects against cognitive deficits in a mouse model of mild traumatic brain injury (mTBI)Neuropharmacology. 2016 Feb;101:506-18. doi: 10.1016\/j.neuropharm.2015.10.014. Epub 2015 Oct 22.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry (IHC), Nissl staining, Western blot, Brain water content, grip test, spectrophotometer, Neurological Severity Score (NSS)
Citation: Liang J, Wu S, Xie W, He H. Ketamine ameliorates oxidative stress-induced apoptosis in experimental traumatic brain injury via the Nrf2 pathwayDrug Des Devel Ther. 2018 Apr 16;12:845-853. doi: 10.2147\/DDDT.S160046. eCollection 2018. PMC5907785
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunohistochemistry (IHC), Nissl staining, Western blot, grip test, spectrophotometer
Citation: Fu C, Wang Q, Zhai X, Gao J. Sinomenine reduces neuronal cell apoptosis in mice after traumatic brain injury via its effect on mitochondrial pathwayDrug Des Devel Ther. 2018 Jan 5;12:77-84. doi: 10.2147\/DDDT.S154391. eCollection 2018. PMC5759853
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Western blot, X-ray
Citation: Rubovitch V, Shachar A, Werner H, Pick CG.Neurochem Int. 2011 Mar;58(4):443-6. doi: 10.1016/j.neuint.2011.01.009. Epub 2011 Jan 8.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Hang test, Immunofluorescence, Nissl staining, Western blot, tail suspension test
Citation: Selvakumar GP, Ahmed ME, Iyer SS, Thangavel R, Kempuraj D, Raikwar SP, Bazley K, Wu K, Khan A, Kukulka K, Bussinger B, Zaheer S, Burton C, James D, Zaheer A. Absence of Glia Maturation Factor Protects from Axonal Injury and Motor Behavioral Impairments after Traumatic Brain InjuryExp Neurobiol. 2020 Jun 30;29(3):230-248. doi: 10.5607\/en20017. PMC7344375
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Corticosterone Enzyme Assay, Novel object recognition test, OxiSelect Total Antioxidant Capacity Assay, Y Maze, immunoblot
Citation: Doulames VM, Vilcans M, Lee S, Shea TB. Social interaction attenuates the extent of secondary neuronal damage following closed head injury in miceFront Behav Neurosci. 2015 Oct 15;9:275. doi: 10.3389\/fnbeh.2015.00275. eCollection 2015. PMC4606018
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Histology, Morris Water Maze (MWM)
Citation: Shishido H, Kishimoto Y, Kawai N, Toyota Y, Ueno M, Kubota T, Kirino Y, Tamiya T. Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer's diseaseNeurosci Lett. 2016 Aug 26;629:62-67. doi: 10.1016\/j.neulet.2016.06.066. Epub 2016 Jun 29.
TBI Model Type: Other
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Electroretinogram, Light aversion, NanoString analysis, qPCR, optic nerve axon counts, RT-PCR
Citation: Honig MG, Del Mar NA, Henderson DL, O'Neal D, Doty JB, Cox R, Li C, Perry AM, Moore BM, Reiner A. Raloxifene Modulates Microglia and Rescues Visual Deficits and Pathology After Impact Traumatic Brain InjuryFront Neurosci. 2021 Oct 29;15:701317. doi: 10.3389\/fnins.2021.701317. eCollection 2021. PMC8585747
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Beam walk test, Elevated plus maze, Forced swim test, Novel context mismatch test, open field test, qRT-PCR
Citation: Kahriman A, Bouley J, Bosco DA, Shazeeb MS, Henninger N. Differential association of baseline body weight and body-weight loss with neurological deficits, histology, and death after repetitive closed head traumatic brain injuryNeurosci Lett. 2022 Feb 6;771:136430. doi: 10.1016\/j.neulet.2021.136430. Epub 2021 Dec 29. PMC8821174
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Enzyme-linked immunosorbent assay (ELISA), GC-MS analysis, Metabolomic Analysis, Y-maze, discrimination index, Novel object recognition test, open field test
Citation: Alqahtani F, Assiri MA, Mohany M, Imran I, Javaid S, Rasool MF, Shakeel W, Sivandzade F, Alanazi AZ, Al-Rejaie SS, Alshammari MA, Alasmari F, Alanazi MM, Alamri FF. Coadministration of Ketamine and Perampanel Improves Behavioral Function and Reduces Inflammation in Acute Traumatic Brain Injury Mouse ModelBiomed Res Int. 2020 Dec 10;2020:3193725. doi: 10.1155\/2020\/3193725. eCollection 2020. PMC7749776
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunofluorescence, TUNEL staining, Western blot, spectrophotometer
Citation: Dai W, Wang H, Fang J, Zhu Y, Zhou J, Wang X, Zhou Y, Zhou M. Curcumin provides neuroprotection in model of traumatic brain injury via the Nrf2-ARE signaling pathwayBrain Res Bull. 2018 Jun;140:65-71. doi: 10.1016\/j.brainresbull.2018.03.020. Epub 2018 Apr 4.
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Immunohistochemical, Tomography
Citation: Harper MM, Boehme N, Dutca LM, Anderson MG. The Retinal Ganglion Cell Response to Blast-Mediated Traumatic Brain Injury Is Genetic Background DependentInvest Ophthalmol Vis Sci. 2021 Jun 1;62(7):13. doi: 10.1167\/iovs.62.7.13. PMC8196410
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Institute of Cancer Research
Assessments: DTI, Graph theory, MRI, WM tractography
Citation: Meningher I, Bernstein-Eliav M, Rubovitch V, Pick CG, Tavor I.Alterations in Network Connectivity after Traumatic Brain Injury in MiceJ Neurotrauma. 2020 Oct 15;37(20):2169-2179. doi: 10.1089/neu.2020.7063. Epub 2020 Jun 11.10.1089/neu.2020.7063
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Enzyme-linked immunoassay, Open field test, Western blotting, biochemical, molecular
Citation: Sivandzade F, Alqahtani F, Sifat A, Cucullo L.The cerebrovascular and neurological impact of chronic smoking on post-traumatic brain injury outcome and recovery: an in vivo studyJ Neuroinflammation. 2020 Apr 27;17(1):133. doi: 10.1186/s12974-020-01818-0.PMC718471710.1186/s12974-020-01818-0
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Behavioral, Cell viability, ELISA, Elevated Plus Maze, TNF-α assay, Y-Maze, cAMP assay, novel object recognition
Citation: Li Y, Glotfelty EJ, Namdar I, Tweedie D, Olson L, Hoffer BJ, DiMarchi RD, Pick CG, Greig NH.Neurotrophic and neuroprotective effects of a monomeric GLP-1/GIP/Gcg receptor triagonist in cellular and rodent models of mild traumatic brain injuryExp Neurol. 2020 Feb;324:113113. doi: 10.1016/j.expneurol.2019.113113. Epub 2019 Nov 12.10.1016/j.expneurol.2019.113113
