On page 3 showing 41 ~ 60 out of 420 results
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: RT-PCR
Citation: Sandhir R, Berman NE. Age-dependent response of CCAAT\/enhancer binding proteins following traumatic brain injury in miceNeurochem Int. 2010 Jan;56(1):188-93. doi: 10.1016\/j.neuint.2009.10.002. Epub 2009 Oct 13. PMC2815015
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Image analysis, Magnetic resonance imaging (MRI)
Citation: Zhang H, Wang W, Jiang S, Zhang Y, Heo HY, Wang X, Peng Y, Wang J, Zhou J. Amide proton transfer-weighted MRI detection of traumatic brain injury in ratsJ Cereb Blood Flow Metab. 2017 Oct;37(10):3422-3432. doi: 10.1177\/0271678X17690165. Epub 2017 Jan 27. PMC5624391
TBI Model Type: Blast model
Organism Species: rat
Organism Strain: Long-Evans
Assessments: Contextual fear memory testing, Novel object recognition test, Sound-attenuated isolation, elevated zero maze apparatus, Immunohistochemistry (IHC), light/dark emergence task
Citation: Perez Garcia G, Perez GM, Otero-Pagan A, Abutarboush R, Kawoos U, De Gasperi R, Gama Sosa MA, Pryor D, Hof PR, Cook DG, Gandy S, Ahlers ST, Elder GA. Transcranial Laser Therapy Does Not Improve Cognitive and Post-Traumatic Stress Disorder-Related Behavioral Traits in Rats Exposed to Repetitive Low-Level Blast InjuryNeurotrauma Rep. 2021 Dec 2;2(1):548-563. doi: 10.1089\/neur.2021.0005. eCollection 2021. PMC8655798
TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Wistar
Assessments: Diffusion Tensor Imaging scan, Neurological Severity Score (NSS)
Citation: Nakuci J, McGuire M, Schweser F, Poulsen D, Muldoon SF. Differential Patterns of Change in Brain Connectivity Resulting from Severe Traumatic Brain InjuryBrain Connect. 2022 May 5. doi: 10.1089\/brain.2021.0168. Online ahead of print.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Elevated plus maze, Forced swim test, Horizontal ladder beam, Immunohistochemistry (IHC), Morris Water Maze (MWM), Rotarod, Tail suspension test, Western Blots, optical fractionator probe
Citation: Gold EM, Vasilevko V, Hasselmann J, Tiefenthaler C, Hoa D, Ranawaka K, Cribbs DH, Cummings BJ. Repeated Mild Closed Head Injuries Induce Long-Term White Matter Pathology and Neuronal Loss That Are Correlated With Behavioral DeficitsASN Neuro. 2018 Jan-Dec;10:1759091418781921. doi: 10.1177\/1759091418781921. PMC6050992
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Biochemical Assay, Brain water content, Hematoxylin and Eosin, Immunohistochemistry (IHC), modified Neurological Severity Score (mNSS), qRT-PCR, TUNEL staining, Western blot
Citation: Tang Y, Dong X, Chen G, Ye W, Kang J, Tang Y, Feng Z. Vagus Nerve Stimulation Attenuates Early Traumatic Brain Injury by Regulating the NF-κB\/NLRP3 Signaling PathwayNeurorehabil Neural Repair. 2020 Sep;34(9):831-843. doi: 10.1177\/1545968320948065. Epub 2020 Aug 10.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Body temperature, Blood gas analysis, blood pH, laser doppler flowmetry
Citation: Roof RL, Hall ED. Estrogen-related gender difference in survival rate and cortical blood flow after impact-acceleration head injury in ratsJ Neurotrauma. 2000 Dec;17(12):1155-69. doi: 10.1089\/neu.2000.17.1155.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Blood–brain barrier permeability, glutathione levels, Histology, malondialdehyde (MDA)
Citation: Özevren H, Deveci E, Tuncer MC. Histopathological changes in the choroid plexus after traumatic brain injury in the rats: a histologic and immunohistochemical studyFolia Morphol (Warsz). 2018;77(4):642-648. doi: 10.5603\/FM.a2018.0029. Epub 2018 Mar 23.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6-SJLF1
Assessments: Conditioned fear testing, Morris Water Maze (MWM), Rotorod test, Histology, shock sensitivity testing
Citation: Brody DL, Mac Donald C, Kessens CC, Yuede C, Parsadanian M, Spinner M, Kim E, Schwetye KE, Holtzman DM, Bayly PV. Electromagnetic controlled cortical impact device for precise, graded experimental traumatic brain injuryJ Neurotrauma. 2007 Apr;24(4):657-73. doi: 10.1089\/neu.2006.0011. PMC2435168
TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: up-down method, von Frey filament, DNIC assessment, Immunohistochemistry (IHC)
Citation: Irvine KA, Peters CM, Vazey EM, Ferguson AR, Clark D. DREADD-mediated activation of the locus coeruleus restores descending nociceptive inhibition after traumatic brain injury in ratsJ Neurotrauma. 2022 Apr 12. doi: 10.1089\/neu.2021.0485. Online ahead of print.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Amyloid precursor protein, Cortical contusion volume, Immunoglobulin, Immunohistochemistry (IHC), Morris Water Maze (MWM), Neurological Severity Score (NSS), Neuroscore, Regional hippocampal neurodegeneration
Citation: Pleasant JM, Carlson SW, Mao H, Scheff SW, Yang KH, Saatman KE. Rate of neurodegeneration in the mouse controlled cortical impact model is influenced by impactor tip shape: implications for mechanistic and therapeutic studiesJ Neurotrauma. 2011 Nov;28(11):2245-62. doi: 10.1089\/neu.2010.1499. Epub 2011 Apr 21. PMC3218388
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Acoustic startle response, Body curl test, Elevated-plus maze, Forced swim test, Lesion volume, Morris Water Maze (MWM), open field test, prepulse inhibition
Citation: Washington PM, Forcelli PA, Wilkins T, Zapple DN, Parsadanian M, Burns MP. The effect of injury severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in miceJ Neurotrauma. 2012 Sep;29(13):2283-96. doi: 10.1089\/neu.2012.2456. Epub 2012 Aug 3. PMC3430487
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Long-Evans
Assessments: Immunohistochemistry (IHC), Cresyl violet staining
Citation: Meaney DF, Ross DT, Winkelstein BA, Brasko J, Goldstein D, Bilston LB, Thibault LE, Gennarelli TA. Modification of the cortical impact model to produce axonal injury in the rat cerebral cortexJ Neurotrauma. 1994 Oct;11(5):599-612. doi: 10.1089\/neu.1994.11.599.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Accelerometer measurement, Immunohistochemistry (IHC)
Citation: Viano DC, Hamberger A, Bolouri H, Säljö A. Evaluation of three animal models for concussion and serious brain injuryAnn Biomed Eng. 2012 Jan;40(1):213-26. doi: 10.1007\/s10439-011-0386-2. Epub 2011 Oct 20.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: modified Neurological Severity Score (mNSS), Neurological examination, Sensorimotor examination, Nissl staining, light/dark anxiety transition test, conditioned passive avoidance response, elevated plus-maze, histology, Hematoxylin and Eosin
Citation: Plekhova NG, Radkov IV, Zinoviev SV, Dyuizen IV, Baryshev AN, Shumatov VB. Effect of Mild Traumatic Brain Injury on Behavioral Reactions and Neocortical Morphology in RatsBull Exp Biol Med. 2021 Mar;170(5):672-676. doi: 10.1007\/s10517-021-05130-6. Epub 2021 Mar 31.
TBI Model Type: Controlled cortical impact model
Organism Species: pig
Organism Strain: Yorkshire
Assessments: Intracranial Pressure (ICP), Nissl staining, Fluoro-Jade B staining (FJB), NeuN staining, cerebral perfusion pressure, heart rate, mean arterial blood pressure (MAP)
Citation: Manley GT, Rosenthal G, Lam M, Morabito D, Yan D, Derugin N, Bollen A, Knudson MM, Panter SS. Controlled cortical impact in swine: pathophysiology and biomechanicsJ Neurotrauma. 2006 Feb;23(2):128-39. doi: 10.1089\/neu.2006.23.128.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: mean arterial blood pressure (MAP), Fluoro-Jade C staining (FJC), Hematoxylin and Eosin
Citation: Dennis AM, Haselkorn ML, Vagni VA, Garman RH, Janesko-Feldman K, Bayir H, Clark RS, Jenkins LW, Dixon CE, Kochanek PM. Hemorrhagic shock after experimental traumatic brain injury in mice: effect on neuronal deathJ Neurotrauma. 2009 Jun;26(6):889-99. doi: 10.1089\/neu.2008.0512. PMC2694227
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry, Novel object recognition test, Y-Maze, elevated plus maze test, staircase test
Citation: Qubty D, Rubovitch V, Benromano T, Ovadia M, Pick CG. Orally Administered Cinnamon Extract Attenuates Cognitive and Neuronal Deficits Following Traumatic Brain InjuryJ Mol Neurosci. 2021 Jan;71(1):178-186. doi: 10.1007\/s12031-020-01688-4. Epub 2020 Sep 8.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Object Recognition Memory Test, Open-Field Test, Western blot, Brain Water Content, qRT-PCR
Citation: Furtado ABV, Gonçalves DF, Hartmann DD, Courtes AA, Cassol G, Nunez-Figueredo Y, Argolo DS, do Nascimento RP, Costa SL, da Silva VDA, Royes LFF, Soares FAA. JM-20 Treatment After Mild Traumatic Brain Injury Reduces Glial Cell Pro-inflammatory Signaling and Behavioral and Cognitive Deficits by Increasing Neurotrophin ExpressionMol Neurobiol. 2021 Sep;58(9):4615-4627. doi: 10.1007\/s12035-021-02436-4. Epub 2021 Jun 19.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Fluoro-Jade C staining (FJC), Immunohistochemistry (IHC)
Citation: Hetzer SM, Shalosky EM, Torrens JN, Evanson NK. Chronic Histological Outcomes of Indirect Traumatic Optic Neuropathy in Adolescent Mice: Persistent Degeneration and Temporally Regulated Glial ResponsesCells. 2021 Nov 28;10(12):3343. doi: 10.3390\/cells10123343. PMC8699438
