On page 3 showing 41 ~ 47 out of 47 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, M29, 79-dichlorodihydrofluorescein diacetate (DCFH-DA) staining, Morris Water Maze, Neurological Severity Scores, Nissl staining, TdT-mediated dUTP Nick-End Labeling, We performed modified Neurological Severity Scores (mNSS), rotarod test, and Morris Water Maze (MWM) test, respectively (n = 8 for each group), enzyme linked immunosorbent assay, immunofluorescence, immunohistochemistry, quantitative real time polymerase chain reaction, rotarod test, western blot
Citation: Wang H, Zhou XM, Wu LY, Liu GJ, Xu WD, Zhang XS, Gao YY, Tao T, Zhou Y, Lu Y, Wang J, Deng CL, Zhuang Z, Hang CH, Li W.Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injuryJ Neuroinflammation. 2020 Jun 15;17(1):188. doi: 10.1186/s12974-020-01863-9.PMC729463110.1186/s12974-020-01863-9
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain Water, H & E stain, Immunofluorescence, Immunohistochemistry, Western Blot
Citation: Yi HJ, Lee JE, Lee DH, Kim YI, Cho CB, Kim IS, Sung JH, Yang SH.The role of NLRP3 in traumatic brain injury and its regulation by pioglitazoneJ Neurosurg. 2019 Sep 27;133(4):1083-1091. doi: 10.3171/2019.6.JNS1954. Print 2020 Oct 1.10.3171/2019.6.JNS1954
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Immunofluorescence, Processing brain tissue for histology
At 1, 3, 7 and 14 dpi, mice were deeply anesthetized (100 mg/kg sodium pentobarbital) and transcardially perfused with cold phosphate-buffered saline (PBS) followed by 4% paraformaldehyde (PFA) at 4°C, Western blotting, histology
Citation: Dong W, Sun Y, Cheng H, Yang B, Wang L, Jiang Z, Li B, Wen S, Guo X, Guan D, Zhao R.Dynamic cell type-specific expression of Nrf2 after traumatic brain injury in miceEur J Neurosci. 2019 Jul;50(2):1981-1993. doi: 10.1111/ejn.14399. Epub 2019 Apr 23.10.1111/ejn.14399
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, ELISA, Morris water maze (MWM), qrt-PCR, Western blot, Immunofluorescence, hematoxylin and eosin, Inclined plane test, modified Neurologic Severity Score (mNSS)
Citation: Mao SS, Hua R, Zhao XP, Qin X, Sun ZQ, Zhang Y, Wu YQ, Jia MX, Cao JL, Zhang YM.J Neurotrauma. 2012 Jul 1;29(10):1941-59. doi: 10.1089/neu.2011.2244.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Cytotoxicity assay, Enzyme-linked immunosorbent assay (ELISA), Fluoro-Jade B, Immunofluorescence, TUNEL staining, Western blot analysis, modified Neurological Severity Score, wet/dry method
Citation: Zhu HT, Bian C, Yuan JC, Chu WH, Xiang X, Chen F, Wang CS, Feng H, Lin JK.Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury.J Neuroinflammation. 2014 Mar 27;11:59. doi: 10.1186/1742-2094-11-59.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Grip Test, Brain Water Content, Immunofluorescence, Immunohistochemical Staining, Mitochondrial MDA and SOD Content, Prussian Blue Staining, Reactive Oxygen Species (ROS) Content, Terminal Deoxynucleotidyl Transferase-Mediated dUTP Nick End Labeling (TUNEL) Analysis, Western Blot, dihydroethidium (DHE) staining
Citation: Xu J, Wang H, Ding K, Zhang L, Wang C, Li T, Wei W, Lu X.Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE pathway.Free Radic Biol Med. 2014 Jun;71:186-195. doi: 10.1016/j.freeradbiomed.2014.03.009. Epub 2014 Mar 15.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Western blot, Immunofluorescence
Citation: Kallakuri S, Kreipke CW, Schafer PC, Schafer SM, Rafols JA.Neuroscience. 2010 Jul 14;168(3):820-30. doi: 10.1016/j.neuroscience.2010.01.018. Epub 2010 Feb 6.
