On page 24 showing 461 ~ 480 out of 498 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Cerebral edema, Lesion volume
Citation: Mansfield RT, Schiding JK, Hamilton RL, Kochanek PM.Effects of hypothermia on traumatic brain injury in immature ratsJ Cereb Blood Flow Metab. 1996 Mar;16(2):244-52. doi: 10.1097/00004647-199603000-00009.10.1097/00004647-199603000-00009
Organism Species: mouse
Assessments: Enzyme-linked immunosorbent assay, Western blot analysis, dry weight method, terminal deoxynucleotidyl transferase- mediated dUTP nick end labeling
Citation: Yu ZQ, Zha JH.Genetic ablation of toll-like receptor 2 reduces secondary brain injury caused by cortical contusion in miceAnn Clin Lab Sci. 2012 Winter;42(1):26-33.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Confocal microscopy, Immunohistochemistry, Immunostaining, NAD+/NADH assay
Citation: Won SJ, Choi BY, Yoo BH, Sohn M, Ying W, Swanson RA, Suh SW.Prevention of traumatic brain injury-induced neuron death by intranasal delivery of nicotinamide adenine dinucleotideJ Neurotrauma. 2012 May 1;29(7):1401-9. doi: 10.1089/neu.2011.2228. Epub 2012 Apr 17.PMC597277510.1089/neu.2011.2228
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry (IHC), Novel object recognition test, Y Maze test
Citation: Rachmany L, Tweedie D, Rubovitch V, Yu QS, Li Y, Wang JY, Pick CG, Greig NH.Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α.PLoS One. 2013 Nov 28;8(11):e79837. doi: 10.1371/journal.pone.0079837. eCollection 2013.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: micro-CT analysis, RT-PCR, three-point bending
Citation: Yu H, Watt H, Mohan S.The negative impact of traumatic brain injury (TBI) on bone in a mouse model.Brain Inj. 2014;28(2):244-51. doi: 10.3109/02699052.2013.859735. Epub 2013 Dec 2.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague–Dawley
Assessments: Immunohistochemistry
Citation: Arnberg F, Gahm C, Mathiesen T.L-N-iminoethyl-lysine after experimental brain trauma attenuates cellular proliferation and astrocyte differentiationActa Neurochir (Wien). 2012 Apr;154(4):681-7. doi: 10.1007/s00701-012-1282-8.10.1007/s00701-012-1282-8
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Western blot, ELISA
Citation: Carballosa-Gonzalez MM, Vitores A, Hentall ID.Hindbrain raphe stimulation boosts cyclic adenosine monophosphate and signaling proteins in the injured spinal cord.Brain Res. 2014 Jan 16;1543:165-72. doi: 10.1016/j.brainres.2013.11.013. Epub 2013 Nov 16.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunofluorescence staining, Transmission electron microscopy, Western blot
Citation: Sun L, Gao J, Zhao M, Jing X, Cui Y, Xu X, Wang K, Zhang W, Cui J.The effects of BMSCs transplantation on autophagy by CX43 in the hippocampus following traumatic brain injury in rats.Neurol Sci. 2014 May;35(5):677-82. doi: 10.1007/s10072-013-1575-6. Epub 2013 Nov 13.
TBI Model Type: Weight-drop model
Organism Species: rabbit
Assessments: Magnetic Resonance Imaging
Citation: Wei XE, Wang D, Li MH, Zhang YZ, Li YH, Li WB.A useful tool for the initial assessment of blood-brain barrier permeability after traumatic brain injury in rabbits: dynamic contrast-enhanced magnetic resonance imagingJ Trauma. 2011 Dec;71(6):1645-50; discussion 1650-1. doi: 10.1097/TA.0b013e31823498eb.10.1097/TA.0b013e31823498eb
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: BALB/c
Assessments: Histopathological, Immunohistochemistry, Western blotting, xenogen imaging
Citation: Lopez NE, Krzyzaniak MJ, Blow C, Putnam J, Ortiz-Pomales Y, Hageny AM, Eliceiri B, Coimbra R, Bansal V.Ghrelin prevents disruption of the blood-brain barrier after traumatic brain injuryJ Neurotrauma. 2012 Jan 20;29(2):385-93. doi: 10.1089/neu.2011.2053. Epub 2011 Oct 26.PMC327971810.1089/neu.2011.2053
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: No strain reported
Assessments: Immunohistochemistry (IHC), Ladder walk, Neurological Severity Score (NSS), open field test, qRT-PCR, Western blot
Citation: Förstner P, Knöll B. Interference of neuronal activity-mediated gene expression through serum response factor deletion enhances mortality and hyperactivity after traumatic brain injuryFASEB J. 2020 Mar;34(3):3855-3873. doi: 10.1096\/fj.201902257RR. Epub 2020 Jan 12.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Foot fault test, Immunohistochemitry (IHC), Morris Water Maze (MWM), open field test, qRT-PCR, Western blot
Citation: Lan YL, Wang X, Zou YJ, Xing JS, Lou JC, Zou S, Ma BB, Ding Y, Zhang B. Bazedoxifene protects cerebral autoregulation after traumatic brain injury and attenuates impairments in blood-brain barrier damage: involvement of anti-inflammatory pathways by blocking MAPK signalingInflamm Res. 2019 Apr;68(4):311-323. doi: 10.1007\/s00011-019-01217-z. Epub 2019 Jan 31.
TBI Model Type: Weight-drop model
Organism Species: mouse
Assessments: Immunohistochemical, Neurological, behavioral assessment, histochemical analyses, immunoblotting
Citation: Kane MJ, Angoa-Pérez M, Briggs DI, Viano DC, Kreipke CW, Kuhn DM.A mouse model of human repetitive mild traumatic brain injuryJ Neurosci Methods. 2012 Jan 15;203(1):41-9. doi: 10.1016/j.jneumeth.2011.09.003. Epub 2011 Sep 12.PMC322191310.1016/j.jneumeth.2011.09.003
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Immunohistochemistry (IHC), In-situ hybridization, RT-PCR
Citation: Ampo K, Suzuki A, Konishi H, Kiyama H. Induction of pancreatitis-associated protein (PAP) family members in neurons after traumatic brain injuryJ Neurotrauma. 2009 Oct;26(10):1683-93. doi: 10.1089\/neu.2008.0847.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: balb/c
Assessments: Histologic, In Vivo Intestinal Permeability Assay, Levels of Intestinal TNF-α, Polymerase Chain Reaction of Intestinal Glial Fibrillary Acidic Protein
Citation: Bansal V, Costantini T, Ryu SY, Peterson C, Loomis W, Putnam J, Elicieri B, Baird A, Coimbra R.Stimulating the central nervous system to prevent intestinal dysfunction after traumatic brain injuryJ Trauma. 2010 May;68(5):1059-64. doi: 10.1097/TA.0b013e3181d87373.PMC425157910.1097/TA.0b013e3181d87373
TBI Model Type: Weight-drop model
Organism Species: Zebrafish
Assessments: Vascular injury, cognitive, fluid content, recovery rate
Citation: Hentig J, Cloghessy K, Dunseath C, Hyde DR.A Scalable Model to Study the Effects of Blunt-Force Injury in Adult ZebrafishJ Vis Exp. 2021 May 31;(171). doi: 10.3791/62709.10.3791/62709
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain Water Content, Immunohistochemistry (IHC), Nissl Staining, Western blot, grip test, Spectrophotometer
Citation: Xu J, Shi J, Zhang J, Zhang Y.Folia Neuropathol. 2018;56(3):179-186. doi: 10.5114/fn.2018.78697.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Neurological Severity Score, Terminal deoxynucleotidyl transferase dUTP nick end labeling, Western blotting, brain water content, oxidative stress
Citation: Liu C, He D, Zhao Q.Licoricidin improves neurological dysfunction after traumatic brain injury in mice via regulating FoxO3/Wnt/β-catenin pathwayJ Nat Med. 2020 Sep;74(4):767-776. doi: 10.1007/s11418-020-01434-5. Epub 2020 Jul 12.10.1007/s11418-020-01434-5
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: B6C3F1
Assessments: Nissl staining, blood-brain barrier integrity, Novel object test, Histology, Latency to right, Mean arterial pressure, Morris water maze (MWM)
Citation: DeFord SM, Wilson MS, Rice AC, Clausen T, Rice LK, Barabnova A, Bullock R, Hamm RJ.J Neurotrauma. 2002 Apr;19(4):427-38. doi: 10.1089/08977150252932389.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Lipid peroxidation assay, qRT-PCR
Citation: Emir M, Ozisik K, Cagli K, Ozisik P, Tuncer S, Bakuy V, Yildirim E, Kilinc K, Gol K.Tohoku J Exp Med. 2005 Oct;207(2):119-24. doi: 10.1620/tjem.207.119.
