On page 22 showing 421 ~ 440 out of 498 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemical, electrophoretic
mobility shift assay, enzyme-linked immunosorbent assay
Citation: Jin W, Wang H, Yan W, Xu L, Wang X, Zhao X, Yang X, Chen G, Ji Y.Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injuryMediators Inflamm. 2008;2008:725174. doi: 10.1155/2008/725174. Epub 2009 Jan 25.PMC263040510.1155/2008/725174
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Citation: Durmaz R, Kasapoglu E, Vural M, Çolak Ö, Aydar Y, Bal C, Atasoy MA.AA-861 appears to suppress leukocyte infiltration induced by traumatic brain injury in ratsNeurosciences (Riyadh). 2008 Jul;13(3):217-26.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Immunofluorescence Double Labeling, NKCC1 Messenger RNA Assay, Neuron Damage, Water Content Measurement, Western Blot
Citation: Lu KT, Cheng NC, Wu CY, Yang YL.NKCC1-mediated traumatic brain injury-induced brain edema and neuron death via Raf/MEK/MAPK cascadeCrit Care Med. 2008 Mar;36(3):917-22. doi: 10.1097/CCM.0B013E31816590C4.10.1097/CCM.0B013E31816590C4
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Barnes maze, Simple Neuroassessment of Asymmetric impairment (SNAP), TEM, histopathology, immunohistochemistry, light-dark box, myelin sheath defects, nesting behavior tests, open-field
Citation: Song H, Konan LM, Cui J, Johnson CE, Langenderfer M, Grant D, Ndam T, Simonyi A, White T, Demirci U, Mott DR, Schwer D, Hubler GK, Cernak I, DePalma RG, Gu Z.Ultrastructural brain abnormalities and associated behavioral changes in mice after low-intensity blast exposure.Behav Brain Res. 2018 Jul 16;347:148-157. doi: 10.1016/j.bbr.2018.03.007. Epub 2018 Mar 8.
TBI Model Type: Weight-drop model
Organism Species: rat
Assessments: Double staining, Immunohistochemistry
Citation: Zhang Z, Fauser U, Schluesener HJ.Early attenuation of lesional interleukin-16 up-regulation by dexamethasone and FTY720 in experimental traumatic brain injuryNeuropathol Appl Neurobiol. 2008 Jun;34(3):330-9. doi: 10.1111/j.1365-2990.2007.00893.x. Epub 2007 Nov 5.10.1111/j.1365-2990.2007.00893.x
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Global and phospho-proteomes, Liquid chromatography-mass spectrometry (LC-MS/MS), Simple Neuroassessment of Asymmetric imPairment (SNAP) test, silver staining, KEGG pathway analysis, STRING network
Citation: Chen M, Song H, Cui J, Johnson CE, Hubler GK, DePalma RG, Gu Z, Xia W.Proteomic Profiling of Mouse Brains Exposed to Blast-Induced Mild Traumatic Brain Injury Reveals Changes in Axonal Proteins and Phosphorylated Tau.J Alzheimers Dis. 2018;66(2):751-773. doi: 10.3233/JAD-180726.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Citation: Geeraerts T, Friggeri A, Mazoit JX, Benhamou D, Duranteau J, Vigué B.Posttraumatic brain vulnerability to hypoxia-hypotension: the importance of the delay between brain trauma and secondary insultIntensive Care Med. 2008 Mar;34(3):551-60. doi: 10.1007/s00134-007-0863-0. Epub 2007 Oct 16.10.1007/s00134-007-0863-0
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: mEPSCs, home-cage monitoring (HCM), CognitionWall, label-free quantitative proteomics, STRING Protein interaction
Citation: Chen S, Siedhoff HR, Zhang H, Liu P, Balderrama A, Li R, Johnson C, Greenlief CM, Koopmans B, Hoffman T, DePalma RG, Li DP, Cui J, Gu Z.Low-intensity blast induces acute glutamatergic hyperexcitability in mouse hippocampus leading to long-term learning deficits and altered expression of proteins involved in synaptic plasticity and serine protease inhibitors.Neurobiol Dis. 2022 Apr;165:105634. doi: 10.1016/j.nbd.2022.105634. Epub 2022 Jan 22.
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Electron Microscopic, electroencephalographies
Citation: Ucar T, Tanriover G, Gurer I, Onal MZ, Kazan S.Modified experimental mild traumatic brain injury modelJ Trauma. 2006 Mar;60(3):558-65. doi: 10.1097/01.ta.0000209172.75637.db.10.1097/01.ta.0000209172.75637.db
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunohistochemical Staining, SOD Activity and Malondialdehyde (MDA) Level, Western Blot analysis, assay kits, neurological severity score, wet/dry weight ratio method
Citation: Lu XY, Wang HD, Xu JG, Ding K, Li T.Deletion of Nrf2 Exacerbates Oxidative Stress After Traumatic Brain Injury in Mice.Cell Mol Neurobiol. 2015 Jul;35(5):713-21. doi: 10.1007/s10571-015-0167-9. Epub 2015 Mar 3.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Evans Blue dye, Immunocytochemistry (IHC), Lesion volume, flow cytometry, Neurologic Severity Score (NSS), rt-PCR, TUNEL staining
Citation: Mencl S, Hennig N, Hopp S, Schuhmann MK, Albert-Weissenberger C, Sirén AL, Kleinschnitz C.J Neuroimmunol. 2014 Sep 15;274(1-2):125-31. doi: 10.1016/j.jneuroim.2014.07.010. Epub 2014 Jul 22.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Citrulline Assay, Fluoro-Jade Staining, Immunohistochemistry, NeuN-staining, TUNEL Staining
Citation: Gahm C, Danilov A, Holmin S, Wiklund PN, Brundin L, Mathiesen T.Reduced neuronal injury after treatment with NG-nitro-L-arginine methyl ester (L-NAME) or 2-sulfo-phenyl-N-tert-butyl nitrone (S-PBN) following experimental brain contusionNeurosurgery. 2005 Dec;57(6):1272-81; discussion 1272-81. doi: 10.1227/01.neu.0000187317.32529.06.10.1227/01.neu.0000187317.32529.06
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Citation: Santos A, Borges N, Cerejo A, Sarmento A, Azevedo I.Catalase activity and thiobarbituric acid reactive substances (TBARS) production in a rat model of diffuse axonal injury. Effect of gadolinium and amilorideNeurochem Res. 2005 May;30(5):625-31. doi: 10.1007/s11064-005-2750-9.10.1007/s11064-005-2750-9
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Citation: Suh SW, Frederickson CJ, Danscher G.Neurotoxic zinc translocation into hippocampal neurons is inhibited by hypothermia and is aggravated by hyperthermia after traumatic brain injury in ratsJ Cereb Blood Flow Metab. 2006 Feb;26(2):161-9. doi: 10.1038/sj.jcbfm.9600176.10.1038/sj.jcbfm.9600176
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunohistochemical analysis, Morris
water maze, Western blot analysis, brain water
content
Citation: Li YH, Zhang CL, Zhang XY, Zhou HX, Meng LL.Effects of mild induced hypothermia on hippocampal connexin 43 and glutamate transporter 1 expression following traumatic brain injury in rats.Mol Med Rep. 2015 Mar;11(3):1991-6. doi: 10.3892/mmr.2014.2928. Epub 2014 Nov 12.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Citation: Romine J, Gao X, Chen J.Controlled cortical impact model for traumatic brain injury.J Vis Exp. 2014 Aug 5;(90):e51781. doi: 10.3791/51781.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay, Quantity real-time-polymerase chain reaction, Western blotting, Immunohistochemical staining
Citation: Lv Q, Lan W, Sun W, Ye R, Fan X, Ma M, Yin Q, Jiang Y, Xu G, Dai J, Guo R, Liu X.Intranasal nerve growth factor attenuates tau phosphorylation in brain after traumatic brain injury in rats.J Neurol Sci. 2014 Oct 15;345(1-2):48-55. doi: 10.1016/j.jns.2014.06.037. Epub 2014 Jun 24.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Enzyme-Linked Immunosorbent Assay, Immunofluorescence staining, Nissl staining, Terminal deoxynucleotidyl transferase-mediated dUTP nick 3′-end labeling (TUNEL), Western blot analysis, neurological severity score
Citation: Ding K, Wang H, Xu J, Lu X, Zhang L, Zhu L.Melatonin reduced microglial activation and alleviated neuroinflammation induced neuron degeneration in experimental traumatic brain injury: Possible involvement of mTOR pathway.Neurochem Int. 2014 Oct;76:23-31. doi: 10.1016/j.neuint.2014.06.015. Epub 2014 Jul 1.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Torsion test, Nissl staining, Prussian blue, rt-PCR
Citation: Yu H, Wergedal JE, Rundle CH, Mohan S.J Rehabil Res Dev. 2014;51(9):1427-37. doi: 10.1682/JRRD.2014.04.0095.
TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunohistochemistry, electrophysiological recordings
Citation: Liu Y, Liu Z, Li X, Luo B, Xiong J, Gan W, Jiang M, Zhang Z, Schluesener HJ, Zhang Z.Accumulation of connective tissue growth factor+ cells during the early phase of rat traumatic brain injury.Diagn Pathol. 2014 Jul 10;9:141. doi: 10.1186/1746-1596-9-141.
