On page 20 showing 381 ~ 400 out of 420 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: SpragueDawley
Assessments: ESR ANALYSIS, HISTOPATHOLOGY, ascorbate oxidase
Citation: Awasthi D, Church DF, Torbati D, Carey ME, Pryor WA.Oxidative stress following traumatic brain injury in ratsSurg Neurol. 1997 Jun;47(6):575-81; discussion 581-2. doi: 10.1016/s0090-3019(96)00461-2.10.1016/s0090-3019(96)00461-2
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: thiobarbituric acid method, Water content, Western Blot Analysis, modified Neurological Severity Score
Citation: Cui QJ, Wang LY, Wei ZX, Qu WS.Continual naringin treatment benefits the recovery of traumatic brain injury in rats through reducing oxidative and inflammatory alterations.Neurochem Res. 2014 Jul;39(7):1254-62. doi: 10.1007/s11064-014-1306-2. Epub 2014 Apr 13.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Citation: Sakamoto KI, Fujisawa H, Koizumi H, Tsuchida E, Ito H, Sadamitsu D, Maekawa T.Effects of mild hypothermia on nitric oxide synthesis following contusion trauma in the ratJ Neurotrauma. 1997 May;14(5):349-53. doi: 10.1089/neu.1997.14.349.10.1089/neu.1997.14.349
TBI Model Type: Weight-drop model
Organism Species: mouse
Assessments: Immunohistochemistry, TUNEL staining, Western blot analysis, neurological severity score
Citation: Zhao Y, Luo P, Guo Q, Li S, Zhang L, Zhao M, Xu H, Yang Y, Poon W, Fei Z.Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivoExp Neurol. 2012 Oct;237(2):489-98. doi: 10.1016/j.expneurol.2012.07.004. Epub 2012 Jul 22.10.1016/j.expneurol.2012.07.004
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague–Dawley
Citation: Marklund N, Salci K, Lewén A, Hillered L.Glycerol as a marker for post-traumatic membrane phospholipid degradation in rat brainNeuroreport. 1997 Apr 14;8(6):1457-61. doi: 10.1097/00001756-199704140-00026.10.1097/00001756-199704140-00026
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Cytotoxicity assay, Enzyme-linked immunosorbent assay (ELISA), Fluoro-Jade B, Immunofluorescence, TUNEL staining, Western blot analysis, modified Neurological Severity Score, wet/dry method
Citation: Zhu HT, Bian C, Yuan JC, Chu WH, Xiang X, Chen F, Wang CS, Feng H, Lin JK.Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury.J Neuroinflammation. 2014 Mar 27;11:59. doi: 10.1186/1742-2094-11-59.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: balb/c
Assessments: Histopathologic Evaluation, Immunohistochemistry
Citation: Lopez NE, Krzyzaniak MJ, Costantini TW, Putnam J, Hageny AM, Eliceiri B, Coimbra R, Bansal V.Vagal nerve stimulation decreases blood-brain barrier disruption after traumatic brain injuryJ Trauma Acute Care Surg. 2012 Jun;72(6):1562-6. doi: 10.1097/TA.0b013e3182569875.10.1097/TA.0b013e3182569875
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Grip Test, Brain Water Content, Immunofluorescence, Immunohistochemical Staining, Mitochondrial MDA and SOD Content, Prussian Blue Staining, Reactive Oxygen Species (ROS) Content, Terminal Deoxynucleotidyl Transferase-Mediated dUTP Nick End Labeling (TUNEL) Analysis, Western Blot, dihydroethidium (DHE) staining
Citation: Xu J, Wang H, Ding K, Zhang L, Wang C, Li T, Wei W, Lu X.Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE pathway.Free Radic Biol Med. 2014 Jun;71:186-195. doi: 10.1016/j.freeradbiomed.2014.03.009. Epub 2014 Mar 15.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57Bl/6
Assessments: Immunohistochemistry, Neurobehavioral Evaluation, Real-Time PCR
Citation: Albert-Weissenberger C, Stetter C, Meuth SG, Göbel K, Bader M, Sirén AL, Kleinschnitz C.Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activationJ Cereb Blood Flow Metab. 2012 Sep;32(9):1747-56. doi: 10.1038/jcbfm.2012.62. Epub 2012 May 9.PMC343462510.1038/jcbfm.2012.62
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Neurological severity score (NSS), Passive avoidance test
Citation: Khalin I, Alyautdin R, Wong TW, Gnanou J, Kocherga G, Kreuter J.Drug Deliv. 2016 Nov;23(9):3520-3528. doi: 10.1080/10717544.2016.1199609. Epub 2016 Jul 16.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague–Dawley
Assessments: Histopathological, Neurological, Physiological
Citation: Adelson PD, Robichaud P, Hamilton RL, Kochanek PM.A model of diffuse traumatic brain injury in the immature ratJ Neurosurg. 1996 Nov;85(5):877-84. doi: 10.3171/jns.1996.85.5.0877.10.3171/jns.1996.85.5.0877
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Cerebral edema, Lesion volume
Citation: Mansfield RT, Schiding JK, Hamilton RL, Kochanek PM.Effects of hypothermia on traumatic brain injury in immature ratsJ Cereb Blood Flow Metab. 1996 Mar;16(2):244-52. doi: 10.1097/00004647-199603000-00009.10.1097/00004647-199603000-00009
Organism Species: mouse
Assessments: Enzyme-linked immunosorbent assay, Western blot analysis, dry weight method, terminal deoxynucleotidyl transferase- mediated dUTP nick end labeling
Citation: Yu ZQ, Zha JH.Genetic ablation of toll-like receptor 2 reduces secondary brain injury caused by cortical contusion in miceAnn Clin Lab Sci. 2012 Winter;42(1):26-33.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Confocal microscopy, Immunohistochemistry, Immunostaining, NAD+/NADH assay
Citation: Won SJ, Choi BY, Yoo BH, Sohn M, Ying W, Swanson RA, Suh SW.Prevention of traumatic brain injury-induced neuron death by intranasal delivery of nicotinamide adenine dinucleotideJ Neurotrauma. 2012 May 1;29(7):1401-9. doi: 10.1089/neu.2011.2228. Epub 2012 Apr 17.PMC597277510.1089/neu.2011.2228
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry (IHC), Novel object recognition test, Y Maze test
Citation: Rachmany L, Tweedie D, Rubovitch V, Yu QS, Li Y, Wang JY, Pick CG, Greig NH.Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α.PLoS One. 2013 Nov 28;8(11):e79837. doi: 10.1371/journal.pone.0079837. eCollection 2013.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague–Dawley
Assessments: Immunohistochemistry
Citation: Arnberg F, Gahm C, Mathiesen T.L-N-iminoethyl-lysine after experimental brain trauma attenuates cellular proliferation and astrocyte differentiationActa Neurochir (Wien). 2012 Apr;154(4):681-7. doi: 10.1007/s00701-012-1282-8.10.1007/s00701-012-1282-8
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunofluorescence staining, Transmission electron microscopy, Western blot
Citation: Sun L, Gao J, Zhao M, Jing X, Cui Y, Xu X, Wang K, Zhang W, Cui J.The effects of BMSCs transplantation on autophagy by CX43 in the hippocampus following traumatic brain injury in rats.Neurol Sci. 2014 May;35(5):677-82. doi: 10.1007/s10072-013-1575-6. Epub 2013 Nov 13.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: BALB/c
Assessments: Histopathological, Immunohistochemistry, Western blotting, xenogen imaging
Citation: Lopez NE, Krzyzaniak MJ, Blow C, Putnam J, Ortiz-Pomales Y, Hageny AM, Eliceiri B, Coimbra R, Bansal V.Ghrelin prevents disruption of the blood-brain barrier after traumatic brain injuryJ Neurotrauma. 2012 Jan 20;29(2):385-93. doi: 10.1089/neu.2011.2053. Epub 2011 Oct 26.PMC327971810.1089/neu.2011.2053
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: No strain reported
Assessments: Immunohistochemistry (IHC), Ladder walk, Neurological Severity Score (NSS), open field test, qRT-PCR, Western blot
Citation: Förstner P, Knöll B. Interference of neuronal activity-mediated gene expression through serum response factor deletion enhances mortality and hyperactivity after traumatic brain injuryFASEB J. 2020 Mar;34(3):3855-3873. doi: 10.1096\/fj.201902257RR. Epub 2020 Jan 12.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Foot fault test, Immunohistochemitry (IHC), Morris Water Maze (MWM), open field test, qRT-PCR, Western blot
Citation: Lan YL, Wang X, Zou YJ, Xing JS, Lou JC, Zou S, Ma BB, Ding Y, Zhang B. Bazedoxifene protects cerebral autoregulation after traumatic brain injury and attenuates impairments in blood-brain barrier damage: involvement of anti-inflammatory pathways by blocking MAPK signalingInflamm Res. 2019 Apr;68(4):311-323. doi: 10.1007\/s00011-019-01217-z. Epub 2019 Jan 31.
