On page 2 showing 21 ~ 40 out of 42 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Immunohistochemistry (IHC), Hematoxylin and eosin, modified Neurologic Severity Score (mNSS)
Citation: Bonilla C, Zurita M, Otero L, Aguayo C, Rico MA, Rodríguez A, Vaquero J.J Neurotrauma. 2012 Jan 20;29(2):394-400. doi: 10.1089/neu.2011.2101. Epub 2011 Dec 7.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Enzyme-linked immunosorbent assay (ELISA)
Citation: Kalemci O, Aydin HE, Kizmazoglu C, Kaya I, Yılmaz H, Arda NM. Effects of Quercetin and Mannitol on Erythropoietin Levels in Rats Following Acute Severe Traumatic Brain InjuryJ Korean Neurosurg Soc. 2017 May;60(3):355-361. doi: 10.3340\/jkns.2016.0505.015. Epub 2017 May 1. PMC5426445
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Rotarod test, VTB test, degree of lesion, modified Neurological Severity Score (mNSS)
Citation: Bonilla Horcajo C, Zurita Castillo M, Vaquero Crespo J. Platelet-rich plasma-derived scaffolds increase the benefit of delayed mesenchymal stromal cell therapy after severe traumatic brain injuryCytotherapy. 2018 Mar;20(3):314-321. doi: 10.1016\/j.jcyt.2017.11.012. Epub 2018 Jan 3.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Enzyme-linked immunosorbent assay
Citation: Guvenc G, Kizmazoglu C, Aydin HE. Effect of Mannitol Infusion on Optic Nerve Injury After Acute Traumatic Subarachnoid Hemorrhage and Brain InjuryJ Craniofac Surg. 2018 Oct;29(7):1772-1775. doi: 10.1097\/SCS.0000000000004827.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: ATP Assay, MeDIP-sequencing and analysis, qRT-PCR, STM-SOL method, Western blot, Immunoprecipitation assay
Citation: Balasubramanian N, Jadhav G, Sakharkar AJ. Repeated mild traumatic brain injuries perturb the mitochondrial biogenesis via DNA methylation in the hippocampus of ratMitochondrion. 2021 Nov;61:11-24. doi: 10.1016\/j.mito.2021.09.001. Epub 2021 Sep 9.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Blood gas analysis, Diode array analysis, high-performance liquid chromatography analysis
Citation: Vagnozzi R, Marmarou A, Tavazzi B, Signoretti S, Di Pierro D, del Bolgia F, Amorini AM, Fazzina G, Sherkat S, Lazzarino G. Changes of cerebral energy metabolism and lipid peroxidation in rats leading to mitochondrial dysfunction after diffuse brain injuryJ Neurotrauma. 1999 Oct;16(10):903-13. doi: 10.1089\/neu.1999.16.903.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Wistar
Assessments: Depth of injured tissue
Citation: Eslami M, Ghanbari E, Sayyah M, Etemadi F, Choopani S, Soleimani M, Amiri Z, Hadjighassem M. Traumatic brain injury accelerates kindling epileptogenesis in ratsNeurol Res. 2016 Mar;38(3):269-74. doi: 10.1179\/1743132815Y.0000000086. Epub 2016 Apr 19.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Actophotometer, Acetylcholinesterase Activity, Estimation of nitrite, Estimation of protein, Estimation of reduced glutathione, Estimation of superoxide dismutase, Morris Water Maze (MWM), Preference index, degree of lipid peroxidation, hidden platform task, object recognition task, probe trial, Rotarod
Citation: Kaur A, Jaiswal G, Brar J, Kumar P. Neuroprotective effect of nerolidol in traumatic brain injury associated behavioural comorbidities in ratsToxicol Res (Camb). 2021 Jan 5;10(1):40-50. doi: 10.1093\/toxres\/tfaa100. eCollection 2021 Jan. PMC7885190
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: ELISA antibody kits, Estimation of GABA and glutamate, Estimation of lipid peroxidation, Estimation of nitrite, High-performance liquid chromatography, Morris water maze, exploration behavior test, forelimb grip strength, method of Ellman, method of Lowry, novel object, open field apparatus
Citation: Rana A, Singh S, Deshmukh R, Kumar A.Pharmacological potential of tocopherol and doxycycline against traumatic brain injury-induced cognitive/motor impairment in ratsBrain Inj. 2020 Jul 2;34(8):1039-1050. doi: 10.1080/02699052.2020.1772508. Epub 2020 Jun 4.10.1080/02699052.2020.1772508
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Biochemical, Chemiluminescence, Histopathological
Citation: Demir D, Kuru Bektaşoğlu P, Koyuncuoğlu T, Kandemir C, Akakın D, Yüksel M, Çelikoğlu E, Yeğen BÇ, Gürer B.Neuroprotective effects of mildronate in a rat model of traumatic brain injuryInjury. 2019 Oct;50(10):1586-1592. doi: 10.1016/j.injury.2019.08.036. Epub 2019 Aug 20.10.1016/j.injury.2019.08.036
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: electron microscopy, morphometric evaluation
Citation: Borges N, Cerejo A, Santos A, Sarmento A, Azevedo I. Changes in rat cerebral mitochondrial succinate dehydrogenase activity after brain traumaInt J Neurosci. 2004 Feb;114(2):217-27. doi: 10.1080\/00207450490249419.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Histology, silver nitrate
Citation: Fleishman MY, Yakusheva NY, Malofey YB, Tolstenok IV, Innokentiev AA. Effect of MGHPPGP Peptide Administered during the Post-Traumatic Period on Morphometric Parameters of the Neocortex and Hippocampus, Hepatocytes, and Epithelium of the Tongue and Small Intestine in RatsBull Exp Biol Med. 2020 Feb;168(4):521-524. doi: 10.1007\/s10517-020-04745-5. Epub 2020 Mar 9.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Immunofluorescence Double Labeling, NKCC1 Messenger RNA Assay, Neuron Damage, Water Content Measurement, Western Blot
Citation: Lu KT, Cheng NC, Wu CY, Yang YL.NKCC1-mediated traumatic brain injury-induced brain edema and neuron death via Raf/MEK/MAPK cascadeCrit Care Med. 2008 Mar;36(3):917-22. doi: 10.1097/CCM.0B013E31816590C4.10.1097/CCM.0B013E31816590C4
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Citation: Santos A, Borges N, Cerejo A, Sarmento A, Azevedo I.Catalase activity and thiobarbituric acid reactive substances (TBARS) production in a rat model of diffuse axonal injury. Effect of gadolinium and amilorideNeurochem Res. 2005 May;30(5):625-31. doi: 10.1007/s11064-005-2750-9.10.1007/s11064-005-2750-9
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Citation: Suh SW, Frederickson CJ, Danscher G.Neurotoxic zinc translocation into hippocampal neurons is inhibited by hypothermia and is aggravated by hyperthermia after traumatic brain injury in ratsJ Cereb Blood Flow Metab. 2006 Feb;26(2):161-9. doi: 10.1038/sj.jcbfm.9600176.10.1038/sj.jcbfm.9600176
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: thiobarbituric acid method, Water content, Western Blot Analysis, modified Neurological Severity Score
Citation: Cui QJ, Wang LY, Wei ZX, Qu WS.Continual naringin treatment benefits the recovery of traumatic brain injury in rats through reducing oxidative and inflammatory alterations.Neurochem Res. 2014 Jul;39(7):1254-62. doi: 10.1007/s11064-014-1306-2. Epub 2014 Apr 13.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Citation: Sakamoto KI, Fujisawa H, Koizumi H, Tsuchida E, Ito H, Sadamitsu D, Maekawa T.Effects of mild hypothermia on nitric oxide synthesis following contusion trauma in the ratJ Neurotrauma. 1997 May;14(5):349-53. doi: 10.1089/neu.1997.14.349.10.1089/neu.1997.14.349
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Cerebral edema, Lesion volume
Citation: Mansfield RT, Schiding JK, Hamilton RL, Kochanek PM.Effects of hypothermia on traumatic brain injury in immature ratsJ Cereb Blood Flow Metab. 1996 Mar;16(2):244-52. doi: 10.1097/00004647-199603000-00009.10.1097/00004647-199603000-00009
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Immunohistochemistry (IHC), In-situ hybridization, RT-PCR
Citation: Ampo K, Suzuki A, Konishi H, Kiyama H. Induction of pancreatitis-associated protein (PAP) family members in neurons after traumatic brain injuryJ Neurotrauma. 2009 Oct;26(10):1683-93. doi: 10.1089\/neu.2008.0847.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Lipid peroxidation assay, qRT-PCR
Citation: Emir M, Ozisik K, Cagli K, Ozisik P, Tuncer S, Bakuy V, Yildirim E, Kilinc K, Gol K.Tohoku J Exp Med. 2005 Oct;207(2):119-24. doi: 10.1620/tjem.207.119.
