On page 2 showing 21 ~ 40 out of 43 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Affymetrix microarray profiling, Quantitative reverse transcriptase PCR
Citation: Israelsson C, Wang Y, Kylberg A, Pick CG, Hoffer BJ, Ebendal T.Closed head injury in a mouse model results in molecular changes indicating inflammatory responsesJ Neurotrauma. 2009 Aug;26(8):1307-14. doi: 10.1089/neu.2008.0676.PMC298985610.1089/neu.2008.0676
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Citation: Rutter B, Song H, DePalma RG, Hubler G, Cui J, Gu Z, Johnson CE.Shock Wave Physics as Related to Primary Non-Impact Blast-Induced Traumatic Brain Injury.Mil Med. 2021 Jan 25;186(Suppl 1):601-609. doi: 10.1093/milmed/usaa290.
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Home-cage monitoring, LightSpot test, Spontaneous behaviors, Anxiety-like behaviors
Citation: Siedhoff HR, Chen S, Balderrama A, Sun GY, Koopmans B, DePalma RG, Cui J, Gu Z.Long-Term Effects of Low-Intensity Blast Non-Inertial Brain Injury on Anxiety-Like Behaviors in Mice: Home-Cage Monitoring Assessments.Neurotrauma Rep. 2022 Jan 11;3(1):27-38. doi: 10.1089/neur.2021.0063. eCollection 2022.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Impactor tip motion
Citation: Kim Y, Fu AH, Tucker LB, Liu J, McCabe JT. Characterization of controlled cortical impact devices by high-speed image analysisJ Neurosci Res. 2018 Apr;96(4):501-511. doi: 10.1002\/jnr.24099. Epub 2017 Jul 4.
TBI Model Type: Fluid percussion injury model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: modified Neurological Severity Score (mNSS), qRT-PCR, Western blot, Brain water content, Oxidative Stress Evaluation
Citation: Chen Y, Lu Y, Xu S, Liu M, Chen W, Zhang Y, Wei L, Zhong C. HDAC1 expression is positively correlated with NADPH oxidase 4-mediated oxidative stress in a mouse model of traumatic brain injuryJ Neurophysiol. 2022 May 1;127(5):1438-1444. doi: 10.1152\/jn.00049.2022. Epub 2022 Apr 20.
TBI Model Type: Other
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: cued fear conditioning, social recognition test, tail suspension test, sucrose/water preference test
Citation: Klemenhagen KC, O'Brien SP, Brody DL. Repetitive concussive traumatic brain injury interacts with post-injury foot shock stress to worsen social and depression-like behavior in micePLoS One. 2013 Sep 18;8(9):e74510. doi: 10.1371\/journal.pone.0074510. eCollection 2013. PMC3776826
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Electron Microscopy, Morris Water Maze (MWM), Immunohistochemistry (IHC)
Citation: Shitaka Y, Tran HT, Bennett RE, Sanchez L, Levy MA, Dikranian K, Brody DL. Repetitive closed-skull traumatic brain injury in mice causes persistent multifocal axonal injury and microglial reactivityJ Neuropathol Exp Neurol. 2011 Jul;70(7):551-67. doi: 10.1097\/NEN.0b013e31821f891f. PMC3118973
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Neurological evaluation, Histology, Immunohistochemistry (IHC), Morris Water Maze (MWM), Beam walk test, forepaw contraflexion, Rotarod test, TUNEL staining
Citation: Fox GB, Fan L, Levasseur RA, Faden AI. Sustained sensory\/motor and cognitive deficits with neuronal apoptosis following controlled cortical impact brain injury in the mouseJ Neurotrauma. 1998 Aug;15(8):599-614. doi: 10.1089\/neu.1998.15.599.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Beam walk test, Immunofluorescent, Immunohistochemistry (IHC), Lesion Volume Assessment, Morris Water Maze (MWM)
Citation: Huang SX, Qiu G, Cheng FR, Pei Z, Yang Z, Deng XH, Zhu JH, Chen L, Chen CC, Lin WF, Liu Y, Liu Z, Zhu FQ. Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory ModulationNeurochem Res. 2018 Sep;43(9):1814-1825. doi: 10.1007\/s11064-018-2597-5. Epub 2018 Jul 19.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Electroencephalography, Morris Water Maze (MWM), Neurological Severity Score (NSS), Porsolt forced swim test, electromyography, elevated plus maze, tail suspension test, wire grip test
Citation: Petraglia AL, Plog BA, Dayawansa S, Chen M, Dashnaw ML, Czerniecka K, Walker CT, Viterise T, Hyrien O, Iliff JJ, Deane R, Nedergaard M, Huang JH. The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: a novel mouse model of chronic traumatic encephalopathyJ Neurotrauma. 2014 Jul 1;31(13):1211-24. doi: 10.1089\/neu.2013.3255. Epub 2014 Jun 12. PMC4082360
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Enzyme-linked immunosorbent assay (ELISA)
Citation: Shein SL, Shellington DK, Exo JL, Jackson TC, Wisniewski SR, Jackson EK, Vagni VA, Bayır H, Clark RS, Dixon CE, Janesko-Feldman KL, Kochanek PM. Hemorrhagic shock shifts the serum cytokine profile from pro- to anti-inflammatory after experimental traumatic brain injury in miceJ Neurotrauma. 2014 Aug 15;31(16):1386-95. doi: 10.1089\/neu.2013.2985. PMC4186809
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Apoptosis Assay, Evans blue method, S100β Quantification, Viability Assay, Western blot, necrosis index
Citation: Rosas-Hernandez H, Cuevas E, Escudero-Lourdes C, Lantz SM, Gomez-Crisostomo NP, Sturdivant NM, Balachandran K, Imam SZ, Slikker W Jr, Paule MG, Ali SF. Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain BarrierMol Neurobiol. 2018 Jan;55(1):258-266. doi: 10.1007\/s12035-017-0738-5.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Fluoro-Jade B staining (FJB), Immunofluorescence, Locomotion, Optomotor/Optokinetic Response, Visual Acuity Testing, Western blot, mean fluorescence intensity
Citation: Hetzer SM, Guilhaume-Correa F, Day D, Bedolla A, Evanson NK. Traumatic Optic Neuropathy Is Associated with Visual Impairment, Neurodegeneration, and Endoplasmic Reticulum Stress in Adolescent MiceCells. 2021 Apr 23;10(5):996. doi: 10.3390\/cells10050996. PMC8146890
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Image acquisition, Immunohistochemistry (IHC), Microscopy, reflex, Neurological Severity Score (NSS), Prussian blue
Citation: Kahriman A, Bouley J, Smith TW, Bosco DA, Woerman AL, Henninger N. Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literatureActa Neuropathol Commun. 2021 Jun 29;9(1):118. doi: 10.1186\/s40478-021-01220-8. PMC8243463
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Calcium imaging, Off chip micro-bead assay, Western blot, flow cytometry, righting time
Citation: Ko J, Hemphill MA, Gabrieli D, Wu L, Yelleswarapu V, Lawrence G, Pennycooke W, Singh A, Meaney DF, Issadore D. Smartphone-enabled optofluidic exosome diagnostic for concussion recoverySci Rep. 2016 Aug 8;6:31215. doi: 10.1038\/srep31215. PMC4976377
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Sucrose Preference Test, forced swim test, step down inhibitory avoidance, sucrose preference test, Forced Swim Test, Gait analysis, Passive avoidance, Prepulse Inhibition, righting reflex suppression
Citation: Browne CA, Wulf HA, Jacobson ML, Oyola MG, Wu TJ, Lucki I. Long-term increase in sensitivity to ketamine's behavioral effects in mice exposed to mild blast induced traumatic brain injuryExp Neurol. 2022 Apr;350:113963. doi: 10.1016\/j.expneurol.2021.113963. Epub 2021 Dec 28. PMC8858880
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: AP firing patterns, AP threshold, Electrophysiological recordings, Input resistance, Resting membrane potential, Spontaneous neuronal activity, action potential generation, fast after-hyperpolarizations, hyperpolarization-activated cation current recordings, infrared-differential interference contrast microscopy
Citation: Simmons S, Langlois LD, Oyola MG, Gouty S, Wu TJ, Nugent FS. Blast-Induced Mild Traumatic Brain Injury Alterations of Corticotropin-Releasing Factor Neuronal Activity in the Mouse Hypothalamic Paraventricular NucleusFront Synaptic Neurosci. 2022 Jan 27;13:804898. doi: 10.3389\/fnsyn.2021.804898. eCollection 2021. PMC8828487
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Dichlorofluorescein Diacetate Dye, Immunofluorescence, Neurological Severity Score )NSS), Nissl staining, TUNEL staining, Western Blot, Optical density, qRT-PCR
Citation: Yang XJ, Ling S, Zhou ML, Deng HJ, Qi M, Liu XL, Zhen C, Chen YX, Fan XR, Wu ZY, Ma FC, Rong J, Di GF, Jiang XC. Inhibition of TRPA1 Attenuates Oxidative Stress-induced Damage After Traumatic Brain Injury via the ERK\/AKT Signaling PathwayNeuroscience. 2022 Feb 11;494:51-68. doi: 10.1016\/j.neuroscience.2022.02.003. Online ahead of print.
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Electrophysiology, Elevated plus maze, Immunohistochemistry, Magnetic resonance image, modified Barnes maze, three-chamber social approach task
Citation: Nolan A, Hennessy E, Krukowski K, Guglielmetti C, Chaumeil MM, Sohal VS, Rosi S.J Neurotrauma. 2018 Oct 15;35(20):2425-2434. doi: 10.1089/neu.2018.5731. Epub 2018 Jul 2.10.1089/neu.2018.5731
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Barnes maze, Simple Neuroassessment of Asymmetric impairment (SNAP), TEM, histopathology, immunohistochemistry, light-dark box, myelin sheath defects, nesting behavior tests, open-field
Citation: Song H, Konan LM, Cui J, Johnson CE, Langenderfer M, Grant D, Ndam T, Simonyi A, White T, Demirci U, Mott DR, Schwer D, Hubler GK, Cernak I, DePalma RG, Gu Z.Ultrastructural brain abnormalities and associated behavioral changes in mice after low-intensity blast exposure.Behav Brain Res. 2018 Jul 16;347:148-157. doi: 10.1016/j.bbr.2018.03.007. Epub 2018 Mar 8.
