On page 2 showing 21 ~ 40 out of 420 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL6/J
Assessments: Coulter AcT 10 Hematology Analyzer, Enzyme-linked immunosorbent assay, Platelet aggregometry, Tail bleed times, Thromboelastometry, righting reflex response time
Citation: Martin GE, Xia B, Kim Y, Johnson MD, Veile R, Friend LA, Makley AT, Caldwell CC, Goodman MD. Platelet Function Changes in a Time-Dependent Manner Following Traumatic Brain Injury in a Murine ModelShock. 2018 Nov;50(5):551-556. doi: 10.1097\/SHK.0000000000001056.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Harlan
Assessments: Beam balance test, Morris Water Maze (MWM), Beam task test, Beam walk test
Citation: Cheng JP, Shaw KE, Monaco CM, Hoffman AN, Sozda CN, Olsen AS, Kline AE. A relatively brief exposure to environmental enrichment after experimental traumatic brain injury confers long-term cognitive benefitsJ Neurotrauma. 2012 Nov 20;29(17):2684-8. doi: 10.1089\/neu.2012.2560. Epub 2012 Aug 27. PMC3510443
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: blood pH, Home Cage behavioral test, Immunohistochemistry (IHC), Nissl staining, Rectal temperature, TUNEL staining, Western blot, adhesive removal test, cylinder test, Evans blue dye, mean arterial blood pressure, RT–PCR
Citation: Lee JH, Wei L, Gu X, Wei Z, Dix TA, Yu SP. Therapeutic effects of pharmacologically induced hypothermia against traumatic brain injury in miceJ Neurotrauma. 2014 Aug 15;31(16):1417-30. doi: 10.1089\/neu.2013.3251. Epub 2014 Jul 7. PMC4132583
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Morris Water Maze (MWM)
Citation: Adelson PD, Fellows-Mayle W, Kochanek PM, Dixon CE. Morris water maze function and histologic characterization of two age-at-injury experimental models of controlled cortical impact in the immature ratChilds Nerv Syst. 2013 Jan;29(1):43-53. doi: 10.1007\/s00381-012-1932-4. Epub 2012 Oct 23.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Wistar
Assessments: Neuron-Specific Enolase Light Immuno Assay
Citation: Woertgen C, Rothoerl RD, Brawanski A. Neuron-specific enolase serum levels after controlled cortical impact injury in the ratJ Neurotrauma. 2001 May;18(5):569-73. doi: 10.1089\/089771501300227378.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Image analysis, Morris Water Maze (MWM)
Citation: Barot J, Saxena B. Therapeutic effects of eugenol in a rat model of traumatic brain injury: A behavioral, biochemical, and histological studyJ Tradit Complement Med. 2021 Jan 8;11(4):318-327. doi: 10.1016\/j.jtcme.2021.01.003. eCollection 2021 Jul. PMC8240337
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay (ELISA), Elevated plus maze, Immunofluorescence, open field test, TUNEL staining, Western blot
Citation: Xie LL, Li SS, Fan YJ, Qi MM, Li ZZ. Melatonin alleviates traumatic brain injury-induced anxiety-like behaviors in rats: Roles of the protein kinase A\/cAMP-response element binding signaling pathwayExp Ther Med. 2022 Apr;23(4):248. doi: 10.3892\/etm.2022.11173. Epub 2022 Jan 31. PMC8855513
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: EEG/EMG recording, Neurological Severity Score (NSS), Novel object recognition test, open field test, Hematoxylin and Eosin, Immunofluorescence, uniaxial accelerometer
Citation: Büchele F, Morawska MM, Schreglmann SR, Penner M, Muser M, Baumann CR, Noain D. Novel Rat Model of Weight Drop-Induced Closed Diffuse Traumatic Brain Injury Compatible with Electrophysiological Recordings of Vigilance StatesJ Neurotrauma. 2016 Jul 1;33(13):1171-80. doi: 10.1089\/neu.2015.4001. Epub 2015 Nov 13.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Long-Evans
Assessments: open field test, Corticosterone level, Novel object recognition test, foot fault test, NeuN staining, Cresyl violet staining
Citation: Jamnia N, Urban JH, Stutzmann GE, Chiren SG, Reisenbigler E, Marr R, Peterson DA, Kozlowski DA. A Clinically Relevant Closed-Head Model of Single and Repeat Concussive Injury in the Adult Rat Using a Controlled Cortical Impact DeviceJ Neurotrauma. 2017 Apr 1;34(7):1351-1363. doi: 10.1089\/neu.2016.4517. Epub 2016 Dec 2.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wister
Assessments: Enzyme-linked immunosorbent assay (ELISA), Hematoxylin and Eosin, RT-PCR, Western blot, permeability assay
Citation: Lang Y, Fu F, Sun D, Xi C, Chen F. Labetalol Prevents Intestinal Dysfunction Induced by Traumatic Brain InjuryPLoS One. 2015 Jul 17;10(7):e0133215. doi: 10.1371\/journal.pone.0133215. eCollection 2015. PMC4505891
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar–Kyoto
Assessments: BK channel current, CM-H2DCFDA staining, qRT-PCR, pressure myography
Citation: Szarka N, Pabbidi MR, Amrein K, Czeiter E, Berta G, Pohoczky K, Helyes Z, Ungvari Z, Koller A, Buki A, Toth P. Traumatic Brain Injury Impairs Myogenic Constriction of Cerebral Arteries: Role of Mitochondria-Derived H(2)O(2) and TRPV4-Dependent Activation of BK(ca) ChannelsJ Neurotrauma. 2018 Apr 1;35(7):930-939. doi: 10.1089\/neu.2017.5056. Epub 2018 Jan 12. PMC5865628
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Spectrometer
Citation: Shochat A, Abookasis D. Differential effects of early postinjury treatment with neuroprotective drugs in a mouse model using diffuse reflectance spectroscopyNeurophotonics. 2015 Jan;2(1):015001. doi: 10.1117\/1.NPh.2.1.015001. Epub 2015 Jan 22. PMC4478758
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam walk test, Western blot, accelerometer, modified Neurological Severity Score (mNSS)
Citation: Hsieh TH, Kang JW, Lai JH, Huang YZ, Rotenberg A, Chen KY, Wang JY, Chan SY, Chen SC, Chiang YH, Peng CW. Relationship of mechanical impact magnitude to neurologic dysfunction severity in a rat traumatic brain injury modelPLoS One. 2017 May 26;12(5):e0178186. doi: 10.1371\/journal.pone.0178186. eCollection 2017. PMC5446124
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6 (transgenic)
Assessments: Neurological Severity Score (NSS), Beam walk test, Blood ethanol assay, Blood gas analysis, Blood glial fibrillary acidic protein, Confocal images, Immunostaining, nitrocellulose-membrane sandwich immunoassay
Citation: Chandrasekar A, Olde Heuvel F, Wepler M, Rehman R, Palmer A, Catanese A, Linkus B, Ludolph A, Boeckers T, Huber-Lang M, Radermacher P, Roselli F. The Neuroprotective Effect of Ethanol Intoxication in Traumatic Brain Injury Is Associated with the Suppression of ErbB Signaling in Parvalbumin-Positive InterneuronsJ Neurotrauma. 2018 Nov 15;35(22):2718-2735. doi: 10.1089\/neu.2017.5270. Epub 2018 Jul 23.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Evans blue extravasation, Neurological Severity Score (NSS), Novel object recognition test, Rotarod test, TUNEL staining, Western blot, lactate dehydrogenase release
Citation: Evanson NK, Guilhaume-Correa F, Herman JP, Goodman MD. Optic tract injury after closed head traumatic brain injury in mice: A model of indirect traumatic optic neuropathyPLoS One. 2018 May 10;13(5):e0197346. doi: 10.1371\/journal.pone.0197346. eCollection 2018. PMC5944994
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Hematoxylin and Eosin, Neurological Severity Score (NSS), Nissl staining, Timm stain
Citation: Ezaki J, Shimada R, Shibuya M, Kibayashi K. Hippocampal neuronal degeneration in the traumatic brain injury mouse: non-trivial effect of scalp incisionNeurol Res. 2016 Nov;38(11):994-1002. doi: 10.1080\/01616412.2016.1228746. Epub 2016 Sep 10.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Prussian blue staining, Cerebral blood flow, COIS imaging, Immunohistochemistry (IHC), seizure activity
Citation: Bouley J, Chung DY, Ayata C, Brown RH Jr, Henninger N. Cortical Spreading Depression Denotes Concussion InjuryJ Neurotrauma. 2019 Apr 1;36(7):1008-1017. doi: 10.1089\/neu.2018.5844. Epub 2018 Aug 24. PMC6444888
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57Bl/6
Assessments: Brain water content, Enzyme-Linked Immunosorbent Assay (Enzyme-linked immunosorbent assay), Evans Blue Extravasation, Magnetic resonance imaging (MRI), Western Blot, Y-maze, open-field, rotarod
Citation: Shultz SR, Sun M, Wright DK, Brady RD, Liu S, Beynon S, Schmidt SF, Kaye AH, Hamilton JA, O'Brien TJ, Grills BL, McDonald SJ. Tibial fracture exacerbates traumatic brain injury outcomes and neuroinflammation in a novel mouse model of multitraumaJ Cereb Blood Flow Metab. 2015 Aug;35(8):1339-47. doi: 10.1038\/jcbfm.2015.56. Epub 2015 Apr 8. PMC4528010
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Histology, Morris Water Maze (MWM)
Citation: Smith DH, Soares HD, Pierce JS, Perlman KG, Saatman KE, Meaney DF, Dixon CE, McIntosh TK. A model of parasagittal controlled cortical impact in the mouse: cognitive and histopathologic effectsJ Neurotrauma. 1995 Apr;12(2):169-78. doi: 10.1089\/neu.1995.12.169.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Western blot
Citation: Griesbach GS, Hovda DA, Gomez-Pinilla F, Sutton RL. Voluntary exercise or amphetamine treatment, but not the combination, increases hippocampal brain-derived neurotrophic factor and synapsin I following cortical contusion injury in ratsNeuroscience. 2008 Jun 23;154(2):530-40. doi: 10.1016\/j.neuroscience.2008.04.003. Epub 2008 Apr 9. PMC2441485
