On page 2 showing 21 ~ 31 out of 31 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Albino
Assessments: Chemiluminescence, Enzyme-linked immunosorbent assay (ELISA), Histology, Modified Bederson Neurologic Examination Score, Myeloperoxidase Activity, Novel object recognition test, Y-Maze Test
Citation: Kuru Bektaşoğlu P, Koyuncuoğlu T, Demir D, Sucu G, Akakın D, Peker Eyüboğlu İ, Yüksel M, Çelikoğlu E, Yeğen BÇ, Gürer B. Neuroprotective Effect of Cinnamaldehyde on Secondary Brain Injury After Traumatic Brain Injury in a Rat ModelWorld Neurosurg. 2021 Sep;153:e392-e402. doi: 10.1016\/j.wneu.2021.06.117. Epub 2021 Jul 2.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Barnes Maze test, Basal ROS production, Enzyme-linked immunosorbent assay (ELISA), Fluoro-Jade C staining (FJC), GSH/GSSG activity assay, Hypoxyprobe staining, Neurological Severity Score, NADPH oxidase activity, Novel object recognition test, Western blot, cell viability analysis, Immunocytochemistry, memory recall test
Citation: Ho MH, Yen CH, Hsieh TH, Kao TJ, Chiu JY, Chiang YH, Hoffer BJ, Chang WC, Chou SY. CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injuryRedox Biol. 2021 Oct;46:102067. doi: 10.1016\/j.redox.2021.102067. Epub 2021 Jul 17. PMC8327355
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Lesion Volume, Cresyl Violet Staining, Enzyme-Linked Immunosorbent Assay (Enzyme-linked immunosorbent assay), Grip Strength Test, Immunofluorescence, Novel object recognition test, Rotarod Test, Western blot, Y-Maze Test
Citation: Ahmed ME, Selvakumar GP, Kempuraj D, Raikwar SP, Thangavel R, Bazley K, Wu K, Khan O, Khan A, Zaheer S, Iyer S, Burton C, James D, Zaheer A. Glia Maturation Factor (GMF) Regulates Microglial Expression Phenotypes and the Associated Neurological Deficits in a Mouse Model of Traumatic Brain InjuryMol Neurobiol. 2020 Nov;57(11):4438-4450. doi: 10.1007\/s12035-020-02040-y. Epub 2020 Jul 31.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: CD-1
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Evans blue extravasation, Neurological Severity Score (NSS), Novel object recognition test, Rotarod test, TUNEL staining, Western blot, lactate dehydrogenase release
Citation: Kempuraj D, Ahmed ME, Selvakumar GP, Thangavel R, Raikwar SP, Zaheer SA, Iyer SS, Govindarajan R, Nattanmai Chandrasekaran P, Burton C, James D, Zaheer A. Acute Traumatic Brain Injury-Induced Neuroinflammatory Response and Neurovascular Disorders in the BrainNeurotox Res. 2021 Apr;39(2):359-368. doi: 10.1007\/s12640-020-00288-9. Epub 2020 Sep 21. PMC7502806
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Aggleton index, Immunohistochemistry (IHC), Novel object recognition test, Y-maze, Enzyme-linked immunosorbent assay (ELISA)
Citation: Benady A, Freidin D, Pick CG, Rubovitch V. GM1 ganglioside prevents axonal regeneration inhibition and cognitive deficits in a mouse model of traumatic brain injurySci Rep. 2018 Sep 6;8(1):13340. doi: 10.1038\/s41598-018-31623-y. PMC6127193
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Histology, Immunohistochemitry, Western blot, error ladder walking test, Novel object recognition test
Citation: Li Y, Bader M, Tamargo I, Rubovitch V, Tweedie D, Pick CG, Greig NH. Liraglutide is neurotrophic and neuroprotective in neuronal cultures and mitigates mild traumatic brain injury in miceJ Neurochem. 2015 Dec;135(6):1203-1217. doi: 10.1111\/jnc.13169. Epub 2015 Jun 18. PMC4644713
TBI Model Type: Controlled cortical impact model
Organism Species: ferret
Organism Strain: No strain reported
Assessments: Adhesive tape detection test, Gait, Immunohistochemistry (IHC), Magnetic resonance imaging (MRI), Novel object recognition test, Open field test
Citation: Schwerin SC, Hutchinson EB, Radomski KL, Ngalula KP, Pierpaoli CM, Juliano SL. Establishing the ferret as a gyrencephalic animal model of traumatic brain injury: Optimization of controlled cortical impact proceduresJ Neurosci Methods. 2017 Jun 15;285:82-96. doi: 10.1016\/j.jneumeth.2017.05.010. Epub 2017 May 10. PMC6320441
TBI Model Type: Blast model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: open field test, Novel object recognition test, righting reflex timing, rotating pole test
Citation: Anderson LM, Samineni S, Wilder DM, Lara M, Eken O, Urioste R, Long JB, Arun P. The Neurobehavioral Effects of Buprenorphine and Meloxicam on a Blast-Induced Traumatic Brain Injury Model in the RatFront Neurol. 2021 Oct 12;12:746370. doi: 10.3389\/fneur.2021.746370. eCollection 2021. PMC8545992
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Enzyme-linked immunosorbent assay (ELISA), Immunofluorescence, Novel object recognition test, Toluidine Blue stain, crystal violet staining
Citation: Kempuraj D, Ahmed ME, Selvakumar GP, Thangavel R, Raikwar SP, Zaheer SA, Iyer SS, Burton C, James D, Zaheer A. Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain InjuryMediators Inflamm. 2020 Jun 24;2020:4243953. doi: 10.1155\/2020\/4243953. eCollection 2020. PMC7333064
TBI Model Type: Fluid percussion injury model
Organism Species: mouse
Organism Strain: ICR
Assessments: Morris water maze (MWM), Hidden Platform, Probe Trial, Visible Platform, Novel object recognition test, Y-Maze Test
Citation: Eakin K, Baratz-Goldstein R, Pick CG, Zindel O, Balaban CD, Hoffer ME, Lockwood M, Miller J, Hoffer BJ.Efficacy of N-acetyl cysteine in traumatic brain injury.PLoS One. 2014 Apr 16;9(4):e90617. doi: 10.1371/journal.pone.0090617. eCollection 2014.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry (IHC), Novel object recognition test, Y Maze test
Citation: Rachmany L, Tweedie D, Rubovitch V, Yu QS, Li Y, Wang JY, Pick CG, Greig NH.Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α.PLoS One. 2013 Nov 28;8(11):e79837. doi: 10.1371/journal.pone.0079837. eCollection 2013.
