On page 2 showing 21 ~ 40 out of 55 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Immunohistochemistry (IHC), Neurological examination, RRT, SPRT, Single pellet reaching task, Y-maze test
Citation: Yu KP, Yoon YS, Lee JG, Oh JS, Lee JS, Seog T, Lee HY. Effects of Electric Cortical Stimulation (ECS) and Transcranial Direct Current Stimulation (tDCS) on Rats With a Traumatic Brain InjuryAnn Rehabil Med. 2018 Aug;42(4):502-513. doi: 10.5535\/arm.2018.42.4.502. Epub 2018 Aug 31. PMC6129703
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Histology, Morris Water Maze (MWM)
Citation: Shishido H, Kishimoto Y, Kawai N, Toyota Y, Ueno M, Kubota T, Kirino Y, Tamiya T. Traumatic brain injury accelerates amyloid-β deposition and impairs spatial learning in the triple-transgenic mouse model of Alzheimer's diseaseNeurosci Lett. 2016 Aug 26;629:62-67. doi: 10.1016\/j.neulet.2016.06.066. Epub 2016 Jun 29.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Error ladder test, Histology, Novel objective recognition (NOR) test, Sticky tape test, Western blotting, immunohistochemistry, novel object recognition
Citation: Zakarya R, Sapkota A, Chan YL, Shah J, Saad S, Bottle SE, Oliver BG, Gorrie CA, Chen H.Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injuryNitric Oxide. 2020 Apr 1;97:57-65. doi: 10.1016/j.niox.2020.02.001. Epub 2020 Feb 13.10.1016/j.niox.2020.02.001
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Histology, brain tissue damage, immunocytochemistry, quantify the double-positive cells
Citation: Lee S, Mattingly A, Lin A, Sacramento J, Mannent L, Castel MN, Canolle B, Delbary-Gossart S, Ferzaz B, Morganti JM, Rosi S, Ferguson AR, Manley GT, Bresnahan JC, Beattie MS.J Neuroinflammation. 2016 Apr 22;13(1):88. doi: 10.1186/s12974-016-0544-4.10.1186/s12974-016-0544-4
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Bioanalyzer DIANA mirPath, Histology, RT-PCR, qRT-PCR, Hematoxylin and Eosin
Citation: Chandran R, Sharma A, Bhomia M, Balakathiresan NS, Knollmann-Ritschel BE, Maheshwari RK. Differential expression of microRNAs in the brains of mice subjected to increasing grade of mild traumatic brain injuryBrain Inj. 2017;31(1):106-119. doi: 10.1080\/02699052.2016.1213420. Epub 2016 Nov 7.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: 16S ribosomal RNA gene sequencing, Blood–brain barrier permeability, Enzyme-linked immunosorbent assay (ELISA), Histology, RT-PCR, Western blot, Brain water content, limulus amebocyte lysate assay, Neurological Severity Score (NSS), Rotarod test
Citation: Ma Y, Liu T, Fu J, Fu S, Hu C, Sun B, Fan X, Zhu J. Lactobacillus acidophilus Exerts Neuroprotective Effects in Mice with Traumatic Brain InjuryJ Nutr. 2019 Sep 1;149(9):1543-1552. doi: 10.1093\/jn\/nxz105.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Enzyme-linked immunosorbent assay (ELISA), Morris Water Maze (MWM)
Citation: Luo ML, Pan L, Wang L, Wang HY, Li S, Long ZY, Zeng L, Liu Y. Transplantation of NSCs Promotes the Recovery of Cognitive Functions by Regulating Neurotransmitters in Rats with Traumatic Brain InjuryNeurochem Res. 2019 Dec;44(12):2765-2775. doi: 10.1007\/s11064-019-02897-z. Epub 2019 Nov 7.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: PVG
Assessments: Histology, Enzyme-linked immunosorbent assay (ELISA)
Citation: Vermeij JD, Aslami H, Fluiter K, Roelofs JJ, van den Bergh WM, Juffermans NP, Schultz MJ, Van der Sluijs K, van de Beek D, van Westerloo DJ.Traumatic brain injury in rats induces lung injury and systemic immune suppression.J Neurotrauma. 2013 Dec 15;30(24):2073-9. doi: 10.1089/neu.2013.3060. Epub 2013 Oct 24.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Balb/C
Assessments: Cerebral Tissue Damage, Histology, Neurologic Severity Score (NSS), TUNEL staining, Hematoxylin and eosin
Citation: Reshef A, Shirvan A, Shohami E, Grimberg H, Levin G, Cohen A, Trembovler V, Ziv I.J Neurotrauma. 2008 Jun;25(6):569-80. doi: 10.1089/neu.2007.0341.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Histology
Citation: Mirzayan MJ, Probst C, Samii M, Krettek C, Gharabaghi A, Pape HC, van Griensven M, Samii A. Histopathological features of the brain, liver, kidney and spleen following an innovative polytrauma model of the mouseExp Toxicol Pathol. 2012 Mar;64(3):133-9. doi: 10.1016\/j.etp.2010.07.007. Epub 2010 Aug 4.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Albino
Assessments: Chemiluminescence, Enzyme-linked immunosorbent assay (ELISA), Histology, Modified Bederson Neurologic Examination Score, Myeloperoxidase Activity, Novel object recognition test, Y-Maze Test
Citation: Kuru Bektaşoğlu P, Koyuncuoğlu T, Demir D, Sucu G, Akakın D, Peker Eyüboğlu İ, Yüksel M, Çelikoğlu E, Yeğen BÇ, Gürer B. Neuroprotective Effect of Cinnamaldehyde on Secondary Brain Injury After Traumatic Brain Injury in a Rat ModelWorld Neurosurg. 2021 Sep;153:e392-e402. doi: 10.1016\/j.wneu.2021.06.117. Epub 2021 Jul 2.
TBI Model Type: Controlled cortical impact model
Organism Species: ferret
Organism Strain: No strain reported
Assessments: Histology
Citation: Lighthall JW. Controlled cortical impact: a new experimental brain injury modelJ Neurotrauma. 1988;5(1):1-15. doi: 10.1089\/neu.1988.5.1.
TBI Model Type: Controlled cortical impact model
Organism Species: ferret
Organism Strain: No strain reported
Assessments: Histology
Citation: Lighthall JW, Goshgarian HG, Pinderski CR. Characterization of axonal injury produced by controlled cortical impactJ Neurotrauma. 1990 Summer;7(2):65-76. doi: 10.1089\/neu.1990.7.65.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Dual-luciferase reporter gene assay, Histology, qRT-PCR, TUNEL staining, Western blot, Enzyme-linked immunosorbent assay (ELISA), Neurological Severity Score (NSS)
Citation: Cui C, Zhang D, Sun K, Li H, Xu L, Lin G, Guo Y, Hu J, Chen J, Nong L, Cai Y, Yu D, Yang W, Wang P, Sun Y. Propofol maintains Th17\/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p\/NFATc2\/NF‑κB axisInt J Mol Med. 2021 Jul;48(1):135. doi: 10.3892\/ijmm.2021.4968. Epub 2021 May 26. PMC8148094
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Histology, Microscopy, qRT-PCR, Neurological Severity Score (NSS), hematoma size
Citation: Förstner P, Rehman R, Anastasiadou S, Haffner-Luntzer M, Sinske D, Ignatius A, Roselli F, Knöll B. Neuroinflammation after Traumatic Brain Injury Is Enhanced in Activating Transcription Factor 3 Mutant MiceJ Neurotrauma. 2018 Oct 1;35(19):2317-2329. doi: 10.1089\/neu.2017.5593. Epub 2018 Jun 5.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Neurological evaluation, Histology, Immunohistochemistry (IHC), Morris Water Maze (MWM), Beam walk test, forepaw contraflexion, Rotarod test, TUNEL staining
Citation: Fox GB, Fan L, Levasseur RA, Faden AI. Sustained sensory\/motor and cognitive deficits with neuronal apoptosis following controlled cortical impact brain injury in the mouseJ Neurotrauma. 1998 Aug;15(8):599-614. doi: 10.1089\/neu.1998.15.599.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Antioxidant Assay, Histology, qRT-PCR, intrinsic optical signal
Citation: Aboghazleh R, Parker E, Yang LT, Kaufer D, Dreier JP, Friedman A, van Hameren G. Brainstem and Cortical Spreading Depolarization in a Closed Head Injury Rat ModelInt J Mol Sci. 2021 Oct 28;22(21):11642. doi: 10.3390\/ijms222111642. PMC8584184
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Magnetic resonance imaging (MRI)
Citation: Li W, Long JA, Watts LT, Jiang Z, Shen Q, Li Y, Duong TQ. A quantitative MRI method for imaging blood-brain barrier leakage in experimental traumatic brain injuryPLoS One. 2014 Dec 5;9(12):e114173. doi: 10.1371\/journal.pone.0114173. eCollection 2014. PMC4257611
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Histology, Immunohistochemitry, Western blot, error ladder walking test, Novel object recognition test
Citation: Li Y, Bader M, Tamargo I, Rubovitch V, Tweedie D, Pick CG, Greig NH. Liraglutide is neurotrophic and neuroprotective in neuronal cultures and mitigates mild traumatic brain injury in miceJ Neurochem. 2015 Dec;135(6):1203-1217. doi: 10.1111\/jnc.13169. Epub 2015 Jun 18. PMC4644713
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Histology, Morris Water Maze (MWM), Beam balance test, Beam walk test, memory retention, rotarod
Citation: Hill JL, Kobori N, Zhao J, Rozas NS, Hylin MJ, Moore AN, Dash PK. Traumatic brain injury decreases AMP-activated protein kinase activity and pharmacological enhancement of its activity improves cognitive outcomeJ Neurochem. 2016 Oct;139(1):106-19. doi: 10.1111\/jnc.13726. Epub 2016 Aug 1. PMC5037010
