On page 18 showing 341 ~ 360 out of 498 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Magnetic Resonance Spectroscopy
Citation: Gasparovic C, Arfai N, Smid N, Feeney DM.J Neurotrauma. 2001 Mar;18(3):241-6. doi: 10.1089/08977150151070856.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam walk test, Estimated contusion volume, Nissl staining, Neuronal death, Gliosis rating, Tactile placing
Citation: Stibick DL, Feeney DM.J Neurotrauma. 2001 Mar;18(3):303-12. doi: 10.1089/08977150151070955.
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Calcium imaging, Off chip micro-bead assay, Western blot, flow cytometry, righting time
Citation: Ko J, Hemphill MA, Gabrieli D, Wu L, Yelleswarapu V, Lawrence G, Pennycooke W, Singh A, Meaney DF, Issadore D. Smartphone-enabled optofluidic exosome diagnostic for concussion recoverySci Rep. 2016 Aug 8;6:31215. doi: 10.1038\/srep31215. PMC4976377
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Evans blue dye, Fluoro-jade C staining (FJC), Histology, Immunofluorescence, Neurological Severity Score (NSS), Western blot, Brain water content
Citation: Li H, Sun J, Wang F, Ding G, Chen W, Fang R, Yao Y, Pang M, Lu ZQ, Liu J. Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury miceBrain Res. 2016 Jul 1;1642:70-78. doi: 10.1016\/j.brainres.2016.03.031. Epub 2016 Mar 24.
TBI Model Type: Other
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Enzyme-linked immunosorbent assay (ELISA), qRT-PCR
Citation: He J, Evans CO, Hoffman SW, Oyesiku NM, Stein DG. Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injuryExp Neurol. 2004 Oct;189(2):404-12. doi: 10.1016\/j.expneurol.2004.06.008.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Swiss Albino
Assessments: Enzyme-linked immunosorbent assay (ELISA), Neurological deficit assessment, qRT-PCR, neurological test, RT-PCR
Citation: Lopez-Rodriguez AB, Mela V, Acaz-Fonseca E, Garcia-Segura LM, Viveros MP. CB2 cannabinoid receptor is involved in the anti-inflammatory effects of leptin in a model of traumatic brain injuryExp Neurol. 2016 May;279:274-282. doi: 10.1016\/j.expneurol.2016.03.018. Epub 2016 Mar 19.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6-SJL
Assessments: Beam walk test, Blood ethanol level, Confocal imaging, Neurological Severity Score (NSS), open field test, qRT-PCR, Western blot, histology
Citation: Chandrasekar A, Aksan B, Heuvel FO, Förstner P, Sinske D, Rehman R, Palmer A, Ludolph A, Huber-Lang M, Böckers T, Mauceri D, Knöll B, Roselli F. Neuroprotective effect of acute ethanol intoxication in TBI is associated to the hierarchical modulation of early transcriptional responsesExp Neurol. 2018 Apr;302:34-45. doi: 10.1016\/j.expneurol.2017.12.017. Epub 2018 Jan 4.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Fluoro-Jade B staining (FJB), Garcia test score system, Immunofluorescence staining, RT-PCR, TUNEL staining, Western blot
Citation: Ni H, Rui Q, Xu Y, Zhu J, Gao F, Dang B, Li D, Gao R, Chen G. RACK1 upregulation induces neuroprotection by activating the IRE1-XBP1 signaling pathway following traumatic brain injury in ratsExp Neurol. 2018 Jun;304:102-113. doi: 10.1016\/j.expneurol.2018.03.003. Epub 2018 Mar 6.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6N
Assessments: Elevated plus maze, Histology, Immunohistochemistry (IHC), open field test, Paw preference test, handedness, Neurological Severity Score (NSS)
Citation: Lopez-Caperuchipi S, Kürzinger L, Hopp-Krämer S, Albert-Weißenberger C, Paul MM, Sirén AL, Stetter C. Posttraumatic learning deficits correlate with initial trauma severity and chronic cellular reactions after closed head injury in male miceExp Neurol. 2021 Jul;341:113721. doi: 10.1016\/j.expneurol.2021.113721. Epub 2021 Apr 11.
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Sucrose Preference Test, forced swim test, step down inhibitory avoidance, sucrose preference test, Forced Swim Test, Gait analysis, Passive avoidance, Prepulse Inhibition, righting reflex suppression
Citation: Browne CA, Wulf HA, Jacobson ML, Oyola MG, Wu TJ, Lucki I. Long-term increase in sensitivity to ketamine's behavioral effects in mice exposed to mild blast induced traumatic brain injuryExp Neurol. 2022 Apr;350:113963. doi: 10.1016\/j.expneurol.2021.113963. Epub 2021 Dec 28. PMC8858880
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: GPx, CAT, MDA level, Immunohistochemistry (IHC), RT-PCR, Western blot, modified Neurological Severity Score (mNSS)
Citation: Yuan J, Wang D, Liu Y, Chen X, Zhang H, Shen F, Liu X, Fu J. Hydrogen-rich water attenuates oxidative stress in rats with traumatic brain injury via Nrf2 pathwayJ Surg Res. 2018 Aug;228:238-246. doi: 10.1016\/j.jss.2018.03.024. Epub 2018 Apr 11.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunofluorescence, Malondialdehyde level, Neurological Severity Score (NSS), qRT-PCR, TUNEL staining, Western blot, glutathione peroxidase, superoxide dismutase
Citation: Fang J, Wang H, Zhou J, Dai W, Zhu Y, Zhou Y, Wang X, Zhou M. Baicalin provides neuroprotection in traumatic brain injury mice model through Akt\/Nrf2 pathwayDrug Des Devel Ther. 2018 Aug 10;12:2497-2508. doi: 10.2147\/DDDT.S163951. eCollection 2018. PMC6089097
TBI Model Type: Other
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Nissl staining, light microscope, silver staining, toluidine blue
Citation: Caron AM, Stephenson R. Sleep deprivation does not affect neuronal susceptibility to mild traumatic brain injury in the ratNat Sci Sleep. 2015 Jun 22;7:63-72. doi: 10.2147\/NSS.S82888. eCollection 2015. PMC4482367
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, Fluoro-Jade C staining (FJC), Immunofluorescence, TUNEL staining, Western blot, qPCR, spectrophotometer
Citation: Dong W, Yang B, Wang L, Li B, Guo X, Zhang M, Jiang Z, Fu J, Pi J, Guan D, Zhao R. Curcumin plays neuroprotective roles against traumatic brain injury partly via Nrf2 signalingToxicol Appl Pharmacol. 2018 May 1;346:28-36. doi: 10.1016\/j.taap.2018.03.020. Epub 2018 Mar 21.
TBI Model Type: Blast model
Organism Species: rat
Organism Strain: Long-Evans outbred
Assessments: Electroretinography, Optomotor response, Spectral domain optical coherence tomography, TUNEL staining, Y-maze, Immunohistochemistry (IHC), spectral-domain optical coherence tomography
Citation: Allen RS, Motz CT, Singh A, Feola A, Hutson L, Douglass A, Ramachandra Rao S, Skelton LA, Cardelle L, Bales KL, Chesler K, Gudapati K, Ethier CR, Harper MM, Fliesler SJ, Pardue MT. Dependence of visual and cognitive outcomes on animal holder configuration in a rodent model of blast overpressure exposureVision Res. 2021 Nov;188:162-173. doi: 10.1016\/j.visres.2021.07.008. Epub 2021 Jul 30. PMC8440444
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Magnetic resonance imaging (MRI), Rotarod test, Spin-echo multislice images, T2-weighted image, cylinder forelimb test, spontaneous forelimb test, Gridwalk test, Histology, laterality score
Citation: Onyszchuk G, Al-Hafez B, He YY, Bilgen M, Berman NE, Brooks WM. A mouse model of sensorimotor controlled cortical impact: characterization using longitudinal magnetic resonance imaging, behavioral assessments and histologyJ Neurosci Methods. 2007 Mar 15;160(2):187-96. doi: 10.1016\/j.jneumeth.2006.09.007. Epub 2006 Oct 16. PMC1941707
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57
Assessments: Fluorescence Imaging, LDH assay, Neurological Severity Score (NSS), UV-visible spectra, beam balance, transmission electron microscopy, zeta potential
Citation: Shi J, Li X, Cavagnaro MJ, Cai J, Zhang C, Li N. A Versatile Pep-CPDs Nanoprobe for Rapid Detection of mTBI Biomarker in Clinical Instances and Safe Fluorescence Imaging In Vivo for Improved Weight-Drop Mouse ModelFront Bioeng Biotechnol. 2022 Mar 7;10:807486. doi: 10.3389\/fbioe.2022.807486. eCollection 2022. PMC8942774
TBI Model Type: Blast model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Elevated Plus Maze, Immunohistochemistry (IHC), Histology, Three-Chamber Sociability Test
Citation: Dickerson MR, Murphy SF, Urban MJ, White Z, VandeVord PJ. Chronic Anxiety- and Depression-Like Behaviors Are Associated With Glial-Driven Pathology Following Repeated Blast Induced NeurotraumaFront Behav Neurosci. 2021 Dec 10;15:787475. doi: 10.3389\/fnbeh.2021.787475. eCollection 2021. PMC8703020
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunohistochemistry (IHC), Limb placing test, Performance time rate, RRT, SPRT, Success rate, limb placing test, Hematoxylin and Eosin
Citation: Sun L, Zhao M, Liu M, Su P, Zhang J, Li Y, Yang X, Wu Z. Suppression of FoxO3a attenuates neurobehavioral deficits after traumatic brain injury through inhibiting neuronal autophagyBehav Brain Res. 2018 Jan 30;337:271-279. doi: 10.1016\/j.bbr.2017.08.042. Epub 2017 Sep 6.
TBI Model Type: Blast model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: open field test, Novel object recognition test, righting reflex timing, rotating pole test
Citation: Anderson LM, Samineni S, Wilder DM, Lara M, Eken O, Urioste R, Long JB, Arun P. The Neurobehavioral Effects of Buprenorphine and Meloxicam on a Blast-Induced Traumatic Brain Injury Model in the RatFront Neurol. 2021 Oct 12;12:746370. doi: 10.3389\/fneur.2021.746370. eCollection 2021. PMC8545992
