On page 18 showing 341 ~ 360 out of 420 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Nissl staining, Lipid peroxidation assay, GSH assay, SOD activity, Western blot, Beam balance test, Brain water content, MDA, TUNEL staining
Citation: He Y, Qu S, Wang J, He X, Lin W, Zhen H, Zhang X.Brain Res. 2012 Jan 18;1433:127-36. doi: 10.1016/j.brainres.2011.11.027. Epub 2011 Nov 18.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Immunofluorescence, Processing brain tissue for histology
At 1, 3, 7 and 14 dpi, mice were deeply anesthetized (100 mg/kg sodium pentobarbital) and transcardially perfused with cold phosphate-buffered saline (PBS) followed by 4% paraformaldehyde (PFA) at 4°C, Western blotting, histology
Citation: Dong W, Sun Y, Cheng H, Yang B, Wang L, Jiang Z, Li B, Wen S, Guo X, Guan D, Zhao R.Dynamic cell type-specific expression of Nrf2 after traumatic brain injury in miceEur J Neurosci. 2019 Jul;50(2):1981-1993. doi: 10.1111/ejn.14399. Epub 2019 Apr 23.10.1111/ejn.14399
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Automated Capillary Western Blots, Behavioral, Cerebral Edema, Quantitative Real-Time PCR
Citation: Sun M, Brady RD, van der Poel C, Apted D, Semple BD, Church JE, O'Brien TJ, McDonald SJ, Shultz SR.A Concomitant Muscle Injury Does Not Worsen Traumatic Brain Injury Outcomes in MiceFront Neurol. 2018 Dec 11;9:1089. doi: 10.3389/fneur.2018.01089. eCollection 2018.PMC629786710.3389/fneur.2018.01089
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: EMSA, Immunohistochemistry (IHC), qrt-PCR, Western blot
Citation: Ling HP, Li W, Zhou ML, Tang Y, Chen ZR, Hang CH.J Surg Res. 2013 Jan;179(1):e227-34. doi: 10.1016/j.jss.2012.03.030. Epub 2012 Apr 5.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: IL-1β ELISA
Citation: Rasouli J, Lekhraj R, White NM, Flamm ES, Pilla AA, Strauch B, Casper D.Neurosci Lett. 2012 Jun 21;519(1):4-8. doi: 10.1016/j.neulet.2012.03.089. Epub 2012 Apr 5.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, ELISA, Morris water maze (MWM), qrt-PCR, Western blot, Immunofluorescence, hematoxylin and eosin, Inclined plane test, modified Neurologic Severity Score (mNSS)
Citation: Mao SS, Hua R, Zhao XP, Qin X, Sun ZQ, Zhang Y, Wu YQ, Jia MX, Cao JL, Zhang YM.J Neurotrauma. 2012 Jul 1;29(10):1941-59. doi: 10.1089/neu.2011.2244.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57/BL6J
Assessments: Elevated plus maze, Forced swim tests, Immunohistochemistry, Morris Water Maze, Open field test, Western blot analysis, rotarod testing, sucrose preference test
Citation: Wu L, Kalish BT, Finander B, Cao T, Jin G, Yahya T, Levy ES, Kukreja B, LaRovere ES, Chung JY, Lo EH, Brown-Whalen A, El Khoury J, Kaplan DL, Whalen MJ.J Neurosci. 2022 Mar 23;42(12):2418-2432. doi: 10.1523/JNEUROSCI.0682-21.2021. Epub 2022 Feb 1.10.1523/JNEUROSCI.0682-21.2021
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, Cresyl violet, Forced swim test, Forelimb placement test, Morris water maze test, Novel object recognition, Rotarod test, Sucrose preference test, Tail suspension test, Western blotting, Wire hanging test, enzyme-linked immunosorbent assay, histology, lesion volume, modified neurologic severity score, neuronal death
Citation: Wang J, Jiang C, Zhang K, Lan X, Chen X, Zang W, Wang Z, Guan F, Zhu C, Yang X, Lu H, Wang J.Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathwayFree Radic Biol Med. 2019 Feb 1;131:345-355. doi: 10.1016/j.freeradbiomed.2018.12.014. Epub 2018 Dec 13.10.1016/j.freeradbiomed.2018.12.014
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Foot fault test, Immunohistochemitry (IHC), Morris Water Maze (MWM), open field test, qRT-PCR, Western blot
Citation: Lan YL, Wang X, Zou YJ, Xing JS, Lou JC, Zou S, Ma BB, Ding Y, Zhang B. Bazedoxifene protects cerebral autoregulation after traumatic brain injury and attenuates impairments in blood-brain barrier damage: involvement of anti-inflammatory pathways by blocking MAPK signalingInflamm Res. 2019 Apr;68(4):311-323. doi: 10.1007\/s00011-019-01217-z. Epub 2019 Jan 31.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Rotarod test, Behavioral seizure scoring, video-EEG monitoring
Citation: Efendioglu M, Basaran R, Akca M, Ceman D, Demirtas C, Yildirim M. Combination Therapy of Gabapentin and N-Acetylcysteine Against Posttraumatic Epilepsy in RatsNeurochem Res. 2020 Aug;45(8):1802-1812. doi: 10.1007\/s11064-020-03042-x. Epub 2020 May 5.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Cystometric measurement, Magnetic resonance imaging (MRI), deep brain stimulation
Citation: Praveen Rajneesh C, Lai CH, Chen SC, Hsieh TH, Chin HY, Peng CW. Improved voiding function by deep brain stimulation in traumatic brain-injured animals with bladder dysfunctionsInt Urol Nephrol. 2019 Jan;51(1):41-52. doi: 10.1007\/s11255-018-2028-1. Epub 2018 Nov 24.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: open field test, CatWalk, Erasmus ladder, Grip strength, Immunohistochemistry (IHC), Rotarod test, Treadmill, Running wheel
Citation: Namdar I, Feldman R, Glazer S, Meningher I, Shlobin NA, Rubovitch V, Bikovski L, Been E, Pick CG. Motor Effects of Minimal Traumatic Brain Injury in MiceJ Mol Neurosci. 2020 Mar;70(3):365-377. doi: 10.1007\/s12031-019-01422-9. Epub 2019 Dec 9.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Histology, silver nitrate
Citation: Fleishman MY, Yakusheva NY, Malofey YB, Tolstenok IV, Innokentiev AA. Effect of MGHPPGP Peptide Administered during the Post-Traumatic Period on Morphometric Parameters of the Neocortex and Hippocampus, Hepatocytes, and Epithelium of the Tongue and Small Intestine in RatsBull Exp Biol Med. 2020 Feb;168(4):521-524. doi: 10.1007\/s10517-020-04745-5. Epub 2020 Mar 9.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Behavioral, Elevated plus maze, Fluoro-Jade, Immunohistochemical staining, Novel object recognition, Y-maze, pharmacokinetic
Citation: Bader M, Li Y, Lecca D, Rubovitch V, Tweedie D, Glotfelty E, Rachmany L, Kim HK, Choi HI, Hoffer BJ, Pick CG, Greig NH, Kim DS.Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injuryNeurobiol Dis. 2019 Apr;124:439-453. doi: 10.1016/j.nbd.2018.11.023. Epub 2018 Nov 22.PMC671083110.1016/j.nbd.2018.11.023
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Shang-hai Jiaotong University
Assessments: Behavior test, Morphological and immunohistochemical assays, Navigational test, Probe test
Citation: Han RZ, Hu JJ, Weng YC, Li DF, Huang Y.NMDA receptor antagonist MK-801 reduces neuronal damage and preserves learning and memory in a rat model of traumatic brain injuryNeurosci Bull. 2009 Dec;25(6):367-75. doi: 10.1007/s12264-009-0608-x.PMC555250410.1007/s12264-009-0608-x
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Balb/C
Assessments: Fluoro-Jade B staining, Beam walk test, hematoxylin and eosin
Citation: Lopez NE, Gaston L, Lopez KR, Hageny AM, Putnam J, Eliceiri B, Coimbra R, Bansal V.J Surg Res. 2014 Mar;187(1):230-236. doi: 10.1016/j.jss.2013.09.030. Epub 2013 Oct 7.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemical, electrophoretic
mobility shift assay, enzyme-linked immunosorbent assay
Citation: Jin W, Wang H, Yan W, Xu L, Wang X, Zhao X, Yang X, Chen G, Ji Y.Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injuryMediators Inflamm. 2008;2008:725174. doi: 10.1155/2008/725174. Epub 2009 Jan 25.PMC263040510.1155/2008/725174
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Citation: Durmaz R, Kasapoglu E, Vural M, Çolak Ö, Aydar Y, Bal C, Atasoy MA.AA-861 appears to suppress leukocyte infiltration induced by traumatic brain injury in ratsNeurosciences (Riyadh). 2008 Jul;13(3):217-26.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Immunofluorescence Double Labeling, NKCC1 Messenger RNA Assay, Neuron Damage, Water Content Measurement, Western Blot
Citation: Lu KT, Cheng NC, Wu CY, Yang YL.NKCC1-mediated traumatic brain injury-induced brain edema and neuron death via Raf/MEK/MAPK cascadeCrit Care Med. 2008 Mar;36(3):917-22. doi: 10.1097/CCM.0B013E31816590C4.10.1097/CCM.0B013E31816590C4
TBI Model Type: Blast model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Barnes maze, Simple Neuroassessment of Asymmetric impairment (SNAP), TEM, histopathology, immunohistochemistry, light-dark box, myelin sheath defects, nesting behavior tests, open-field
Citation: Song H, Konan LM, Cui J, Johnson CE, Langenderfer M, Grant D, Ndam T, Simonyi A, White T, Demirci U, Mott DR, Schwer D, Hubler GK, Cernak I, DePalma RG, Gu Z.Ultrastructural brain abnormalities and associated behavioral changes in mice after low-intensity blast exposure.Behav Brain Res. 2018 Jul 16;347:148-157. doi: 10.1016/j.bbr.2018.03.007. Epub 2018 Mar 8.
