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On page 16 showing 301 ~ 320 out of 498 results
Snippet Table

TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Tyrosine Hydroxylase activity, Western blot, microdialysis
Citation: Shin SS, Bray ER, Dixon CE. Effects of nicotine administration on striatal dopamine signaling after traumatic brain injury in ratsJ Neurotrauma. 2012 Mar 20;29(5):843-50. doi: 10.1089\/neu.2011.1966. Epub 2011 Oct 24. PMC3303095

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Intracranial pressure (ICP), Morris Water Maze (MWM), arterial blood gas, blood urea nitrogen, calcium, glucose, hematocrit, hemoglobin, lactate, lesion volme, hemispheric volume, magnesium, neuropathology, osmolarity, potassium, sodium
Citation: Hemerka JN, Wu X, Dixon CE, Garman RH, Exo JL, Shellington DK, Blasiole B, Vagni VA, Janesko-Feldman K, Xu M, Wisniewski SR, Bayır H, Jenkins LW, Clark RS, Tisherman SA, Kochanek PM. Severe brief pressure-controlled hemorrhagic shock after traumatic brain injury exacerbates functional deficits and long-term neuropathological damage in miceJ Neurotrauma. 2012 Aug 10;29(12):2192-208. doi: 10.1089\/neu.2011.2303. PMC3472682

TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: RT-PCR, Western blot
Citation: Shin SS, Bales JW, Yan HQ, Kline AE, Wagner AK, Lyons-Weiler J, Dixon CE. The effect of environmental enrichment on substantia nigra gene expression after traumatic brain injury in ratsJ Neurotrauma. 2013 Feb 15;30(4):259-70. doi: 10.1089\/neu.2012.2462. Epub 2013 Feb 5. PMC3579325

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Neurological evaluation, Histology, Immunohistochemistry (IHC), Morris Water Maze (MWM), Beam walk test, forepaw contraflexion, Rotarod test, TUNEL staining
Citation: Fox GB, Fan L, Levasseur RA, Faden AI. Sustained sensory\/motor and cognitive deficits with neuronal apoptosis following controlled cortical impact brain injury in the mouseJ Neurotrauma. 1998 Aug;15(8):599-614. doi: 10.1089\/neu.1998.15.599.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Blood gas analysis, Diode array analysis, high-performance liquid chromatography analysis
Citation: Vagnozzi R, Marmarou A, Tavazzi B, Signoretti S, Di Pierro D, del Bolgia F, Amorini AM, Fazzina G, Sherkat S, Lazzarino G. Changes of cerebral energy metabolism and lipid peroxidation in rats leading to mitochondrial dysfunction after diffuse brain injuryJ Neurotrauma. 1999 Oct;16(10):903-13. doi: 10.1089\/neu.1999.16.903.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunofluorescence, Immunohistochemistry (IHC), Lesion Volume, Morris Water Maze (MWM), Neurobehavioral Evaluation, Nissl staining, beam walk
Citation: Li D, Ma S, Guo D, Cheng T, Li H, Tian Y, Li J, Guan F, Yang B, Wang J. Environmental Circadian Disruption Worsens Neurologic Impairment and Inhibits Hippocampal Neurogenesis in Adult Rats After Traumatic Brain InjuryCell Mol Neurobiol. 2016 Oct;36(7):1045-55. doi: 10.1007\/s10571-015-0295-2. Epub 2016 Feb 17. PMC4967018

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunofluorescence, Nissl Staining, qRT-PCR, TUNEL staining, Western blot, Neurological Severity Score (NSS)
Citation: Liu Z, Wang H, Shi X, Li L, Zhou M, Ding H, Yang Y, Li X, Ding K. DL-3-n-Butylphthalide (NBP) Provides Neuroprotection in the Mice Models After Traumatic Brain Injury via Nrf2-ARE Signaling PathwayNeurochem Res. 2017 May;42(5):1375-1386. doi: 10.1007\/s11064-017-2186-z. Epub 2017 Feb 18.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Beam walk test, Immunofluorescent, Immunohistochemistry (IHC), Lesion Volume Assessment, Morris Water Maze (MWM)
Citation: Huang SX, Qiu G, Cheng FR, Pei Z, Yang Z, Deng XH, Zhu JH, Chen L, Chen CC, Lin WF, Liu Y, Liu Z, Zhu FQ. Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory ModulationNeurochem Res. 2018 Sep;43(9):1814-1825. doi: 10.1007\/s11064-018-2597-5. Epub 2018 Jul 19.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar–Kyoto
Assessments: qRT-PCR
Citation: Szenasi A, Amrein K, Czeiter E, Szarka N, Toth P, Koller A. Molecular Pathomechanisms of Impaired Flow-Induced Constriction of Cerebral Arteries Following Traumatic Brain Injury: A Potential Impact on Cerebral AutoregulationInt J Mol Sci. 2021 Jun 21;22(12):6624. doi: 10.3390\/ijms22126624. PMC8234931

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Antioxidant Assay, Histology, qRT-PCR, intrinsic optical signal
Citation: Aboghazleh R, Parker E, Yang LT, Kaufer D, Dreier JP, Friedman A, van Hameren G. Brainstem and Cortical Spreading Depolarization in a Closed Head Injury Rat ModelInt J Mol Sci. 2021 Oct 28;22(21):11642. doi: 10.3390\/ijms222111642. PMC8584184

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Electroencephalography, Morris Water Maze (MWM), Neurological Severity Score (NSS), Porsolt forced swim test, electromyography, elevated plus maze, tail suspension test, wire grip test
Citation: Petraglia AL, Plog BA, Dayawansa S, Chen M, Dashnaw ML, Czerniecka K, Walker CT, Viterise T, Hyrien O, Iliff JJ, Deane R, Nedergaard M, Huang JH. The spectrum of neurobehavioral sequelae after repetitive mild traumatic brain injury: a novel mouse model of chronic traumatic encephalopathyJ Neurotrauma. 2014 Jul 1;31(13):1211-24. doi: 10.1089\/neu.2013.3255. Epub 2014 Jun 12. PMC4082360

TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Enzyme-linked immunosorbent assay (ELISA)
Citation: Shein SL, Shellington DK, Exo JL, Jackson TC, Wisniewski SR, Jackson EK, Vagni VA, Bayır H, Clark RS, Dixon CE, Janesko-Feldman KL, Kochanek PM. Hemorrhagic shock shifts the serum cytokine profile from pro- to anti-inflammatory after experimental traumatic brain injury in miceJ Neurotrauma. 2014 Aug 15;31(16):1386-95. doi: 10.1089\/neu.2013.2985. PMC4186809

TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Histology, Magnetic resonance imaging (MRI)
Citation: Li W, Long JA, Watts LT, Jiang Z, Shen Q, Li Y, Duong TQ. A quantitative MRI method for imaging blood-brain barrier leakage in experimental traumatic brain injuryPLoS One. 2014 Dec 5;9(12):e114173. doi: 10.1371\/journal.pone.0114173. eCollection 2014. PMC4257611

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6N
Assessments: IntelliCage Test, object recognition test, Organ Weight to Body Weight Ratio, Immunofluorescence, Neurological Severity Score (NSS)
Citation: Stetter C, Lopez-Caperuchipi S, Hopp-Krämer S, Bieber M, Kleinschnitz C, Sirén AL, Albert-Weißenberger C. Amelioration of Cognitive and Behavioral Deficits after Traumatic Brain Injury in Coagulation Factor XII Deficient MiceInt J Mol Sci. 2021 May 3;22(9):4855. doi: 10.3390\/ijms22094855. PMC8124758

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Apoptosis Assay, Evans blue method, S100β Quantification, Viability Assay, Western blot, necrosis index
Citation: Rosas-Hernandez H, Cuevas E, Escudero-Lourdes C, Lantz SM, Gomez-Crisostomo NP, Sturdivant NM, Balachandran K, Imam SZ, Slikker W Jr, Paule MG, Ali SF. Characterization of Biaxial Stretch as an In Vitro Model of Traumatic Brain Injury to the Blood-Brain BarrierMol Neurobiol. 2018 Jan;55(1):258-266. doi: 10.1007\/s12035-017-0738-5.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Lesion Volume, Cresyl Violet Staining, Enzyme-Linked Immunosorbent Assay (Enzyme-linked immunosorbent assay), Grip Strength Test, Immunofluorescence, Novel object recognition test, Rotarod Test, Western blot, Y-Maze Test
Citation: Ahmed ME, Selvakumar GP, Kempuraj D, Raikwar SP, Thangavel R, Bazley K, Wu K, Khan O, Khan A, Zaheer S, Iyer S, Burton C, James D, Zaheer A. Glia Maturation Factor (GMF) Regulates Microglial Expression Phenotypes and the Associated Neurological Deficits in a Mouse Model of Traumatic Brain InjuryMol Neurobiol. 2020 Nov;57(11):4438-4450. doi: 10.1007\/s12035-020-02040-y. Epub 2020 Jul 31.

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Neurological Severity Score (NSS), Prussian blue staining, Nuclear Fast Red Staining, gas liquid chromatography
Citation: Lecques JD, Kerr BJK, Hillyer LM, Kang JX, Robinson LE, Ma DWL. N-3 Polyunsaturated Fatty Acids Ameliorate Neurobehavioral Outcomes Post-Mild Traumatic Brain Injury in the Fat-1 Mouse ModelNutrients. 2021 Nov 15;13(11):4092. doi: 10.3390\/nu13114092. PMC8620437

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Fluoro-Jade B staining (FJB), Immunofluorescence, Locomotion, Optomotor/Optokinetic Response, Visual Acuity Testing, Western blot, mean fluorescence intensity
Citation: Hetzer SM, Guilhaume-Correa F, Day D, Bedolla A, Evanson NK. Traumatic Optic Neuropathy Is Associated with Visual Impairment, Neurodegeneration, and Endoplasmic Reticulum Stress in Adolescent MiceCells. 2021 Apr 23;10(5):996. doi: 10.3390\/cells10050996. PMC8146890

TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: CD-1
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Evans blue extravasation, Neurological Severity Score (NSS), Novel object recognition test, Rotarod test, TUNEL staining, Western blot, lactate dehydrogenase release
Citation: Kempuraj D, Ahmed ME, Selvakumar GP, Thangavel R, Raikwar SP, Zaheer SA, Iyer SS, Govindarajan R, Nattanmai Chandrasekaran P, Burton C, James D, Zaheer A. Acute Traumatic Brain Injury-Induced Neuroinflammatory Response and Neurovascular Disorders in the BrainNeurotox Res. 2021 Apr;39(2):359-368. doi: 10.1007\/s12640-020-00288-9. Epub 2020 Sep 21. PMC7502806

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Magnetic resonance imaging (MRI), Cystometric measurements, measure external urethral sphincter electromyography
Citation: Praveen Rajneesh C, Liou JC, Hsieh TH, Chin HY, Peng CW. Efficacy of Deep Brain Stimulation on the Improvement of the Bladder Functions in Traumatic Brain Injured RatsBrain Sci. 2020 Nov 12;10(11):850. doi: 10.3390\/brainsci10110850. PMC7698168

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The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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