On page 14 showing 261 ~ 280 out of 498 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Neurological severity score (NSS)
Citation: Ohayon S, Boyko M, Saad A, Douvdevani A, Gruenbaum BF, Melamed I, Shapira Y, Teichberg VI, Zlotnik A.J Neurotrauma. 2012 Jan 20;29(2):261-7. doi: 10.1089/neu.2011.1938. Epub 2011 Dec 7.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawlay
Assessments: TUNEL staining, transmission electron microscope, Enzyme-linked immunosorbent assay (ELISA), Immunofluorescence, Neurological Severity Score (NSS), Morris Water Maze (MWM), Western blot, Brain water content
Citation: Shen M, Wang S, Wen X, Han XR, Wang YJ, Zhou XM, Zhang MH, Wu DM, Lu J, Zheng YL. Dexmedetomidine exerts neuroprotective effect via the activation of the PI3K\/Akt\/mTOR signaling pathway in rats with traumatic brain injuryBiomed Pharmacother. 2017 Nov;95:885-893. doi: 10.1016\/j.biopha.2017.08.125. Epub 2017 Sep 10.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: open field test, CORT level, Novel object recognition test, foot fault test, Immunofluorescence, NeuN staining, Cresyl violet staining
Citation: Baratz R, Tweedie D, Wang JY, Rubovitch V, Luo W, Hoffer BJ, Greig NH, Pick CG. Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in miceJ Neuroinflammation. 2015 Mar 7;12:45. doi: 10.1186\/s12974-015-0237-4. PMC4352276
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Enzyme-linked immunosorbent assay (ELISA)
Citation: Kalemci O, Aydin HE, Kizmazoglu C, Kaya I, Yılmaz H, Arda NM. Effects of Quercetin and Mannitol on Erythropoietin Levels in Rats Following Acute Severe Traumatic Brain InjuryJ Korean Neurosurg Soc. 2017 May;60(3):355-361. doi: 10.3340\/jkns.2016.0505.015. Epub 2017 May 1. PMC5426445
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: open field test, CORT level, Novel object recognition test, foot fault test, Immunofluorescence, NeuN staining, Cresyl violet staining
Citation: Baratz-Goldstein R, Toussia-Cohen S, Elpaz A, Rubovitch V, Pick CG. Immediate and delayed hyperbaric oxygen therapy as a neuroprotective treatment for traumatic brain injury in miceMol Cell Neurosci. 2017 Sep;83:74-82. doi: 10.1016\/j.mcn.2017.06.004. Epub 2017 Jul 8.
TBI Model Type: Other
Organism Species: mouse
Organism Strain: C57BL/6N
Assessments: Autoradiography, Immunohistochemistry (IHC), Neurological Severity Score (NSS), hematoxylin and eosin, μPET
Citation: Israel I, Ohsiek A, Al-Momani E, Albert-Weissenberger C, Stetter C, Mencl S, Buck AK, Kleinschnitz C, Samnick S, Sirén AL. Combined [(18)F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in miceJ Neuroinflammation. 2016 Jun 7;13(1):140. doi: 10.1186\/s12974-016-0604-9. PMC4897946
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Enzyme-linked immunosorbent assay (ELISA), Evans blue dye extravasation, Functional Magnetic resonance imaging (MRI), Immunofluorescence, Western blot, Brain water content, Neurological Severity Score (NSS), wire grip test, motion test
Citation: Yang Q, Zhang S, Xu Z, Liu L, Fan S, Wu S, Ma C. The Effectiveness of Trigeminal Nerve Stimulation on Traumatic Brain InjuryNeuromodulation. 2022 Jan 20:S1094-7159(21)06389-3. doi: 10.1016\/j.neurom.2021.10.014. Online ahead of print.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Rotarod test, VTB test, degree of lesion, modified Neurological Severity Score (mNSS)
Citation: Bonilla Horcajo C, Zurita Castillo M, Vaquero Crespo J. Platelet-rich plasma-derived scaffolds increase the benefit of delayed mesenchymal stromal cell therapy after severe traumatic brain injuryCytotherapy. 2018 Mar;20(3):314-321. doi: 10.1016\/j.jcyt.2017.11.012. Epub 2018 Jan 3.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Enzyme-linked immunosorbent assay
Citation: Guvenc G, Kizmazoglu C, Aydin HE. Effect of Mannitol Infusion on Optic Nerve Injury After Acute Traumatic Subarachnoid Hemorrhage and Brain InjuryJ Craniofac Surg. 2018 Oct;29(7):1772-1775. doi: 10.1097\/SCS.0000000000004827.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: ATP Assay, MeDIP-sequencing and analysis, qRT-PCR, STM-SOL method, Western blot, Immunoprecipitation assay
Citation: Balasubramanian N, Jadhav G, Sakharkar AJ. Repeated mild traumatic brain injuries perturb the mitochondrial biogenesis via DNA methylation in the hippocampus of ratMitochondrion. 2021 Nov;61:11-24. doi: 10.1016\/j.mito.2021.09.001. Epub 2021 Sep 9.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Hippocampal histology, neuron-specific enolase
Citation: Wallen TE, Singer KE, Baucom MR, England LG, Schuster RM, Pritts TA, Goodman MD. Effects of antifibrinolytics on systemic and cerebral inflammation after traumatic brain injuryJ Trauma Acute Care Surg. 2022 Mar 22. doi: 10.1097\/TA.0000000000003607. Online ahead of print.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunohistochemistry (IHC), Nissl Staining, Western blot, Grip test, spectrophotometer
Citation: Zhai X, Ding Y, Wang Q, Zhang H, Li F. Rutin Acid Ameliorates Neural Apoptosis Induced by Traumatic Brain Injury via Mitochondrial Pathways in MiceNeuroimmunomodulation. 2016;23(3):179-187. doi: 10.1159\/000448716. Epub 2016 Sep 20.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Evans blue extravasation, Neurological Severity Score (NSS), Novel object recognition, Rotarod test, TUNEL staining, Western blot, lactate dehydrogenase release
Citation: Wang P, Pan B, Tian J, Yang L, Chen Z, Yang L, Fan Z. Ac-FLTD-CMK inhibits pyroptosis and exerts neuroprotective effect in a mice model of traumatic brain injuryNeuroreport. 2021 Feb 3;32(3):188-197. doi: 10.1097\/WNR.0000000000001580.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Impactor tip motion
Citation: Kim Y, Fu AH, Tucker LB, Liu J, McCabe JT. Characterization of controlled cortical impact devices by high-speed image analysisJ Neurosci Res. 2018 Apr;96(4):501-511. doi: 10.1002\/jnr.24099. Epub 2017 Jul 4.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam walk test, Morris Water Maze (MWM), Beam balance test
Citation: Statler KD, Alexander H, Vagni V, Holubkov R, Dixon CE, Clark RS, Jenkins L, Kochanek PM. Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injuryBrain Res. 2006 Mar 3;1076(1):216-24. doi: 10.1016\/j.brainres.2005.12.106. Epub 2006 Feb 13.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: CF-1
Assessments: Western blot
Citation: Thompson SN, Gibson TR, Thompson BM, Deng Y, Hall ED. Relationship of calpain-mediated proteolysis to the expression of axonal and synaptic plasticity markers following traumatic brain injury in miceExp Neurol. 2006 Sep;201(1):253-65. doi: 10.1016\/j.expneurol.2006.04.013. Epub 2006 Jun 30.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Histology
Citation: Mirzayan MJ, Probst C, Samii M, Krettek C, Gharabaghi A, Pape HC, van Griensven M, Samii A. Histopathological features of the brain, liver, kidney and spleen following an innovative polytrauma model of the mouseExp Toxicol Pathol. 2012 Mar;64(3):133-9. doi: 10.1016\/j.etp.2010.07.007. Epub 2010 Aug 4.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Lewis
Assessments: Lowry’s method, Lung Wet/Dry Ratios, Hematoxylin and Eosin, Immunofluorescence, qRT-PCR, semiquantitative scoring system
Citation: Liu Y, Lu J, Wang X, Chen L, Liu S, Zhang Z, Yao W. Erythropoietin-Derived Peptide Protects Against Acute Lung Injury After Rat Traumatic Brain InjuryCell Physiol Biochem. 2017;41(5):2037-2044. doi: 10.1159\/000475434. Epub 2017 Apr 14.
TBI Model Type: Controlled cortical impact model
Organism Species: pig
Organism Strain: Yorkshire
Assessments: Brain swelling, Total blood volume
Citation: Jin G, DeMoya MA, Duggan M, Knightly T, Mejaddam AY, Hwabejire J, Lu J, Smith WM, Kasotakis G, Velmahos GC, Socrate S, Alam HB. Traumatic brain injury and hemorrhagic shock: evaluation of different resuscitation strategies in a large animal model of combined insults. Shock. 2012 Jul;38(1):49-56. doi: 10.1097\/SHK.0b013e3182574778.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Albino
Assessments: Chemiluminescence, Enzyme-linked immunosorbent assay (ELISA), Histology, Modified Bederson Neurologic Examination Score, Myeloperoxidase Activity, Novel object recognition test, Y-Maze Test
Citation: Kuru Bektaşoğlu P, Koyuncuoğlu T, Demir D, Sucu G, Akakın D, Peker Eyüboğlu İ, Yüksel M, Çelikoğlu E, Yeğen BÇ, Gürer B. Neuroprotective Effect of Cinnamaldehyde on Secondary Brain Injury After Traumatic Brain Injury in a Rat ModelWorld Neurosurg. 2021 Sep;153:e392-e402. doi: 10.1016\/j.wneu.2021.06.117. Epub 2021 Jul 2.
