On page 12 showing 221 ~ 240 out of 420 results
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Enzyme-linked immunosorbent assay
Citation: Guvenc G, Kizmazoglu C, Aydin HE. Effect of Mannitol Infusion on Optic Nerve Injury After Acute Traumatic Subarachnoid Hemorrhage and Brain InjuryJ Craniofac Surg. 2018 Oct;29(7):1772-1775. doi: 10.1097\/SCS.0000000000004827.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: ATP Assay, MeDIP-sequencing and analysis, qRT-PCR, STM-SOL method, Western blot, Immunoprecipitation assay
Citation: Balasubramanian N, Jadhav G, Sakharkar AJ. Repeated mild traumatic brain injuries perturb the mitochondrial biogenesis via DNA methylation in the hippocampus of ratMitochondrion. 2021 Nov;61:11-24. doi: 10.1016\/j.mito.2021.09.001. Epub 2021 Sep 9.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Hippocampal histology, neuron-specific enolase
Citation: Wallen TE, Singer KE, Baucom MR, England LG, Schuster RM, Pritts TA, Goodman MD. Effects of antifibrinolytics on systemic and cerebral inflammation after traumatic brain injuryJ Trauma Acute Care Surg. 2022 Mar 22. doi: 10.1097\/TA.0000000000003607. Online ahead of print.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Immunohistochemistry (IHC), Nissl Staining, Western blot, Grip test, spectrophotometer
Citation: Zhai X, Ding Y, Wang Q, Zhang H, Li F. Rutin Acid Ameliorates Neural Apoptosis Induced by Traumatic Brain Injury via Mitochondrial Pathways in MiceNeuroimmunomodulation. 2016;23(3):179-187. doi: 10.1159\/000448716. Epub 2016 Sep 20.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Evans blue extravasation, Neurological Severity Score (NSS), Novel object recognition, Rotarod test, TUNEL staining, Western blot, lactate dehydrogenase release
Citation: Wang P, Pan B, Tian J, Yang L, Chen Z, Yang L, Fan Z. Ac-FLTD-CMK inhibits pyroptosis and exerts neuroprotective effect in a mice model of traumatic brain injuryNeuroreport. 2021 Feb 3;32(3):188-197. doi: 10.1097\/WNR.0000000000001580.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: Impactor tip motion
Citation: Kim Y, Fu AH, Tucker LB, Liu J, McCabe JT. Characterization of controlled cortical impact devices by high-speed image analysisJ Neurosci Res. 2018 Apr;96(4):501-511. doi: 10.1002\/jnr.24099. Epub 2017 Jul 4.
TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Beam walk test, Morris Water Maze (MWM), Beam balance test
Citation: Statler KD, Alexander H, Vagni V, Holubkov R, Dixon CE, Clark RS, Jenkins L, Kochanek PM. Isoflurane exerts neuroprotective actions at or near the time of severe traumatic brain injuryBrain Res. 2006 Mar 3;1076(1):216-24. doi: 10.1016\/j.brainres.2005.12.106. Epub 2006 Feb 13.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: CF-1
Assessments: Western blot
Citation: Thompson SN, Gibson TR, Thompson BM, Deng Y, Hall ED. Relationship of calpain-mediated proteolysis to the expression of axonal and synaptic plasticity markers following traumatic brain injury in miceExp Neurol. 2006 Sep;201(1):253-65. doi: 10.1016\/j.expneurol.2006.04.013. Epub 2006 Jun 30.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Histology
Citation: Mirzayan MJ, Probst C, Samii M, Krettek C, Gharabaghi A, Pape HC, van Griensven M, Samii A. Histopathological features of the brain, liver, kidney and spleen following an innovative polytrauma model of the mouseExp Toxicol Pathol. 2012 Mar;64(3):133-9. doi: 10.1016\/j.etp.2010.07.007. Epub 2010 Aug 4.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Lewis
Assessments: Lowry’s method, Lung Wet/Dry Ratios, Hematoxylin and Eosin, Immunofluorescence, qRT-PCR, semiquantitative scoring system
Citation: Liu Y, Lu J, Wang X, Chen L, Liu S, Zhang Z, Yao W. Erythropoietin-Derived Peptide Protects Against Acute Lung Injury After Rat Traumatic Brain InjuryCell Physiol Biochem. 2017;41(5):2037-2044. doi: 10.1159\/000475434. Epub 2017 Apr 14.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Albino
Assessments: Chemiluminescence, Enzyme-linked immunosorbent assay (ELISA), Histology, Modified Bederson Neurologic Examination Score, Myeloperoxidase Activity, Novel object recognition test, Y-Maze Test
Citation: Kuru Bektaşoğlu P, Koyuncuoğlu T, Demir D, Sucu G, Akakın D, Peker Eyüboğlu İ, Yüksel M, Çelikoğlu E, Yeğen BÇ, Gürer B. Neuroprotective Effect of Cinnamaldehyde on Secondary Brain Injury After Traumatic Brain Injury in a Rat ModelWorld Neurosurg. 2021 Sep;153:e392-e402. doi: 10.1016\/j.wneu.2021.06.117. Epub 2021 Jul 2.
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Hematoxylin and Eosin, Morris Water Maze (MWM), Brain water content, Immunohistochemistry (IHC), seizure activity, wire-grip test
Citation: Dapul HR, Park J, Zhang J, Lee C, DanEshmand A, Lok J, Ayata C, Gray T, Scalzo A, Qiu J, Lo EH, Whalen MJ. Concussive injury before or after controlled cortical impact exacerbates histopathology and functional outcome in a mixed traumatic brain injury model in miceJ Neurotrauma. 2013 Mar 1;30(5):382-91. doi: 10.1089\/neu.2012.2536. Epub 2013 Feb 20. PMC3593692
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Barnes Maze test, Basal ROS production, Enzyme-linked immunosorbent assay (ELISA), Fluoro-Jade C staining (FJC), GSH/GSSG activity assay, Hypoxyprobe staining, Neurological Severity Score, NADPH oxidase activity, Novel object recognition test, Western blot, cell viability analysis, Immunocytochemistry, memory recall test
Citation: Ho MH, Yen CH, Hsieh TH, Kao TJ, Chiu JY, Chiang YH, Hoffer BJ, Chang WC, Chou SY. CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injuryRedox Biol. 2021 Oct;46:102067. doi: 10.1016\/j.redox.2021.102067. Epub 2021 Jul 17. PMC8327355
TBI Model Type: Fluid percussion injury model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: modified Neurological Severity Score (mNSS), qRT-PCR, Western blot, Brain water content, Oxidative Stress Evaluation
Citation: Chen Y, Lu Y, Xu S, Liu M, Chen W, Zhang Y, Wei L, Zhong C. HDAC1 expression is positively correlated with NADPH oxidase 4-mediated oxidative stress in a mouse model of traumatic brain injuryJ Neurophysiol. 2022 May 1;127(5):1438-1444. doi: 10.1152\/jn.00049.2022. Epub 2022 Apr 20.
TBI Model Type: Controlled cortical impact model
Organism Species: ferret
Organism Strain: No strain reported
Assessments: Histology
Citation: Lighthall JW. Controlled cortical impact: a new experimental brain injury modelJ Neurotrauma. 1988;5(1):1-15. doi: 10.1089\/neu.1988.5.1.
TBI Model Type: Controlled cortical impact model
Organism Species: ferret
Organism Strain: No strain reported
Assessments: Histology
Citation: Lighthall JW, Goshgarian HG, Pinderski CR. Characterization of axonal injury produced by controlled cortical impactJ Neurotrauma. 1990 Summer;7(2):65-76. doi: 10.1089\/neu.1990.7.65.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Dual-luciferase reporter gene assay, Histology, qRT-PCR, TUNEL staining, Western blot, Enzyme-linked immunosorbent assay (ELISA), Neurological Severity Score (NSS)
Citation: Cui C, Zhang D, Sun K, Li H, Xu L, Lin G, Guo Y, Hu J, Chen J, Nong L, Cai Y, Yu D, Yang W, Wang P, Sun Y. Propofol maintains Th17\/Treg cell balance and reduces inflammation in rats with traumatic brain injury via the miR‑145‑3p\/NFATc2\/NF‑κB axisInt J Mol Med. 2021 Jul;48(1):135. doi: 10.3892\/ijmm.2021.4968. Epub 2021 May 26. PMC8148094
TBI Model Type: Other
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: cued fear conditioning, social recognition test, tail suspension test, sucrose/water preference test
Citation: Klemenhagen KC, O'Brien SP, Brody DL. Repetitive concussive traumatic brain injury interacts with post-injury foot shock stress to worsen social and depression-like behavior in micePLoS One. 2013 Sep 18;8(9):e74510. doi: 10.1371\/journal.pone.0074510. eCollection 2013. PMC3776826
TBI Model Type: Other
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Evans blue permeability assay, Immunofluorescence, TUNEL staining, Western blot, modified Neurological Severity Score (mNSS)
Citation: Mannix R, Berkner J, Mei Z, Alcon S, Hashim J, Robinson S, Jantzie L, Meehan WP 3rd, Qiu J. Adolescent Mice Demonstrate a Distinct Pattern of Injury after Repetitive Mild Traumatic Brain InjuryJ Neurotrauma. 2017 Jan 15;34(2):495-504. doi: 10.1089\/neu.2016.4457. Epub 2016 Jul 27. PMC5220578
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Swiss
Assessments: Neurological Score test, Neurological deficit assessment, qRT-PCR, Western Blot, Brain water content
Citation: Lopez-Rodriguez AB, Acaz-Fonseca E, Viveros MP, Garcia-Segura LM. Changes in cannabinoid receptors, aquaporin 4 and vimentin expression after traumatic brain injury in adolescent male mice. Association with edema and neurological deficitPLoS One. 2015 Jun 3;10(6):e0128782. doi: 10.1371\/journal.pone.0128782. eCollection 2015. PMC4454518
