On page 11 showing 201 ~ 220 out of 226 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ddY
Assessments: Gross histological examinatio
Citation: Tang YP, Noda Y, Hasegawa T, Nabeshima T.Effects of VA-045 on learning and memory deficits in traumatic brain injury (TBI)-induced retrograde and anterograde amnesic miceBr J Pharmacol. 1997 Sep;122(2):257-64. doi: 10.1038/sj.bjp.0701385.PMC156493810.1038/sj.bjp.0701385
TBI Model Type: Fluid percussion injury model
Organism Species: mouse
Organism Strain: ICR
Assessments: Morris water maze (MWM), Hidden Platform, Probe Trial, Visible Platform, Novel object recognition test, Y-Maze Test
Citation: Eakin K, Baratz-Goldstein R, Pick CG, Zindel O, Balaban CD, Hoffer ME, Lockwood M, Miller J, Hoffer BJ.Efficacy of N-acetyl cysteine in traumatic brain injury.PLoS One. 2014 Apr 16;9(4):e90617. doi: 10.1371/journal.pone.0090617. eCollection 2014.
TBI Model Type: Weight-drop model
Organism Species: mouse
Assessments: Immunohistochemistry, TUNEL staining, Western blot analysis, neurological severity score
Citation: Zhao Y, Luo P, Guo Q, Li S, Zhang L, Zhao M, Xu H, Yang Y, Poon W, Fei Z.Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivoExp Neurol. 2012 Oct;237(2):489-98. doi: 10.1016/j.expneurol.2012.07.004. Epub 2012 Jul 22.10.1016/j.expneurol.2012.07.004
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Cytotoxicity assay, Enzyme-linked immunosorbent assay (ELISA), Fluoro-Jade B, Immunofluorescence, TUNEL staining, Western blot analysis, modified Neurological Severity Score, wet/dry method
Citation: Zhu HT, Bian C, Yuan JC, Chu WH, Xiang X, Chen F, Wang CS, Feng H, Lin JK.Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury.J Neuroinflammation. 2014 Mar 27;11:59. doi: 10.1186/1742-2094-11-59.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: balb/c
Assessments: Histopathologic Evaluation, Immunohistochemistry
Citation: Lopez NE, Krzyzaniak MJ, Costantini TW, Putnam J, Hageny AM, Eliceiri B, Coimbra R, Bansal V.Vagal nerve stimulation decreases blood-brain barrier disruption after traumatic brain injuryJ Trauma Acute Care Surg. 2012 Jun;72(6):1562-6. doi: 10.1097/TA.0b013e3182569875.10.1097/TA.0b013e3182569875
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Grip Test, Brain Water Content, Immunofluorescence, Immunohistochemical Staining, Mitochondrial MDA and SOD Content, Prussian Blue Staining, Reactive Oxygen Species (ROS) Content, Terminal Deoxynucleotidyl Transferase-Mediated dUTP Nick End Labeling (TUNEL) Analysis, Western Blot, dihydroethidium (DHE) staining
Citation: Xu J, Wang H, Ding K, Zhang L, Wang C, Li T, Wei W, Lu X.Luteolin provides neuroprotection in models of traumatic brain injury via the Nrf2-ARE pathway.Free Radic Biol Med. 2014 Jun;71:186-195. doi: 10.1016/j.freeradbiomed.2014.03.009. Epub 2014 Mar 15.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57Bl/6
Assessments: Immunohistochemistry, Neurobehavioral Evaluation, Real-Time PCR
Citation: Albert-Weissenberger C, Stetter C, Meuth SG, Göbel K, Bader M, Sirén AL, Kleinschnitz C.Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activationJ Cereb Blood Flow Metab. 2012 Sep;32(9):1747-56. doi: 10.1038/jcbfm.2012.62. Epub 2012 May 9.PMC343462510.1038/jcbfm.2012.62
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Neurological severity score (NSS), Passive avoidance test
Citation: Khalin I, Alyautdin R, Wong TW, Gnanou J, Kocherga G, Kreuter J.Drug Deliv. 2016 Nov;23(9):3520-3528. doi: 10.1080/10717544.2016.1199609. Epub 2016 Jul 16.
Organism Species: mouse
Assessments: Enzyme-linked immunosorbent assay, Western blot analysis, dry weight method, terminal deoxynucleotidyl transferase- mediated dUTP nick end labeling
Citation: Yu ZQ, Zha JH.Genetic ablation of toll-like receptor 2 reduces secondary brain injury caused by cortical contusion in miceAnn Clin Lab Sci. 2012 Winter;42(1):26-33.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Immunohistochemistry (IHC), Novel object recognition test, Y Maze test
Citation: Rachmany L, Tweedie D, Rubovitch V, Yu QS, Li Y, Wang JY, Pick CG, Greig NH.Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α.PLoS One. 2013 Nov 28;8(11):e79837. doi: 10.1371/journal.pone.0079837. eCollection 2013.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6J
Assessments: micro-CT analysis, RT-PCR, three-point bending
Citation: Yu H, Watt H, Mohan S.The negative impact of traumatic brain injury (TBI) on bone in a mouse model.Brain Inj. 2014;28(2):244-51. doi: 10.3109/02699052.2013.859735. Epub 2013 Dec 2.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: BALB/c
Assessments: Histopathological, Immunohistochemistry, Western blotting, xenogen imaging
Citation: Lopez NE, Krzyzaniak MJ, Blow C, Putnam J, Ortiz-Pomales Y, Hageny AM, Eliceiri B, Coimbra R, Bansal V.Ghrelin prevents disruption of the blood-brain barrier after traumatic brain injuryJ Neurotrauma. 2012 Jan 20;29(2):385-93. doi: 10.1089/neu.2011.2053. Epub 2011 Oct 26.PMC327971810.1089/neu.2011.2053
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: No strain reported
Assessments: Immunohistochemistry (IHC), Ladder walk, Neurological Severity Score (NSS), open field test, qRT-PCR, Western blot
Citation: Förstner P, Knöll B. Interference of neuronal activity-mediated gene expression through serum response factor deletion enhances mortality and hyperactivity after traumatic brain injuryFASEB J. 2020 Mar;34(3):3855-3873. doi: 10.1096\/fj.201902257RR. Epub 2020 Jan 12.
TBI Model Type: Weight-drop model
Organism Species: mouse
Assessments: Immunohistochemical, Neurological, behavioral assessment, histochemical analyses, immunoblotting
Citation: Kane MJ, Angoa-Pérez M, Briggs DI, Viano DC, Kreipke CW, Kuhn DM.A mouse model of human repetitive mild traumatic brain injuryJ Neurosci Methods. 2012 Jan 15;203(1):41-9. doi: 10.1016/j.jneumeth.2011.09.003. Epub 2011 Sep 12.PMC322191310.1016/j.jneumeth.2011.09.003
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: balb/c
Assessments: Histologic, In Vivo Intestinal Permeability Assay, Levels of Intestinal TNF-α, Polymerase Chain Reaction of Intestinal Glial Fibrillary Acidic Protein
Citation: Bansal V, Costantini T, Ryu SY, Peterson C, Loomis W, Putnam J, Elicieri B, Baird A, Coimbra R.Stimulating the central nervous system to prevent intestinal dysfunction after traumatic brain injuryJ Trauma. 2010 May;68(5):1059-64. doi: 10.1097/TA.0b013e3181d87373.PMC425157910.1097/TA.0b013e3181d87373
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain Water Content, Immunohistochemistry (IHC), Nissl Staining, Western blot, grip test, Spectrophotometer
Citation: Xu J, Shi J, Zhang J, Zhang Y.Folia Neuropathol. 2018;56(3):179-186. doi: 10.5114/fn.2018.78697.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Neurological Severity Score, Terminal deoxynucleotidyl transferase dUTP nick end labeling, Western blotting, brain water content, oxidative stress
Citation: Liu C, He D, Zhao Q.Licoricidin improves neurological dysfunction after traumatic brain injury in mice via regulating FoxO3/Wnt/β-catenin pathwayJ Nat Med. 2020 Sep;74(4):767-776. doi: 10.1007/s11418-020-01434-5. Epub 2020 Jul 12.10.1007/s11418-020-01434-5
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: B6C3F1
Assessments: Nissl staining, blood-brain barrier integrity, Novel object test, Histology, Latency to right, Mean arterial pressure, Morris water maze (MWM)
Citation: DeFord SM, Wilson MS, Rice AC, Clausen T, Rice LK, Barabnova A, Bullock R, Hamm RJ.J Neurotrauma. 2002 Apr;19(4):427-38. doi: 10.1089/08977150252932389.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Free swim test, Neurological assessment, Passive avoidance test, T-maze test
Citation: Milman A, Rosenberg A, Weizman R, Pick CG.J Neurotrauma. 2005 Sep;22(9):1003-10. doi: 10.1089/neu.2005.22.1003.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Morris water maze (MWM), Free swim test
Citation: Zohar O, Getslev V, Miller AL, Schreiber S, Pick CG.Neurosci Lett. 2006 Feb 20;394(3):239-42. doi: 10.1016/j.neulet.2005.10.099. Epub 2005 Dec 13.
