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On page 10 showing 181 ~ 200 out of 249 results
Snippet Table

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Five serial choice reaction time task, Immunohistochemistry (IHC), Western blot
Citation: Kaukas L, Holmes JL, Rahimi F, Collins-Praino L, Corrigan F. Injury during adolescence leads to sex-specific executive function deficits in adulthood in a pre-clinical model of mild traumatic brain injuryBehav Brain Res. 2021 Mar 26;402:113067. doi: 10.1016\/j.bbr.2020.113067. Epub 2020 Dec 14.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Brain water content, Immunohistochemistry (IHC), Neurological evaluation, Nissl staining, TUNEL staining, Western blot, spectrophotometer
Citation: Wei W, Wang H, Wu Y, Ding K, Li T, Cong Z, Xu J, Zhou M, Huang L, Ding H, Wu H. Alpha lipoic acid inhibits neural apoptosis via a mitochondrial pathway in rats following traumatic brain injuryNeurochem Int. 2015 Aug;87:85-91. doi: 10.1016\/j.neuint.2015.06.003. Epub 2015 Jun 6.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Albino
Assessments: Biuret method, Malondialdehyde content, CAT activity, Enzyme-linked immunosorbent assay (ELISA), GSH estimation, Hyper-emotionality test, SOD activity, Sucrose preference test, colorimetric assay, open field test
Citation: Jindal A, Mahesh R, Bhatt S, Pandey D. Molecular modifications by regulating cAMP signaling and oxidant-antioxidant defence mechanisms, produce antidepressant-like effect: A possible mechanism of etazolate aftermaths of impact accelerated traumatic brain injury in rat modelNeurochem Int. 2017 Dec;111:3-11. doi: 10.1016\/j.neuint.2016.12.004. Epub 2016 Dec 14.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunofluorescence, open field test, TUNEL staining, Western blot
Citation: Li SS, Xie LL, Li ZZ, Fan YJ, Qi MM, Xi YG. Androgen is responsible for enhanced susceptibility of melatonin against traumatic brain injury in femalesNeurosci Lett. 2021 May 1;752:135842. doi: 10.1016\/j.neulet.2021.135842. Epub 2021 Mar 22.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunohistochemistry (IHC), Fluoro-Jade C staining (FJC), Neurological function score, TUNEL staining, Brain water content, Western blot
Citation: Zhu J, Lin X, Chen C, Tan H, Gao Y, Li D, Chen G. WNK3 Promotes Neuronal Survival after Traumatic Brain Injury in RatsNeuroscience. 2021 Nov 21;477:76-88. doi: 10.1016\/j.neuroscience.2021.09.021. Epub 2021 Oct 6.

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar Han
Assessments: Barnes Maze test, GC/MS methods, Rotarod test, Enzyme-linked immunosorbent assay (ELISA), ultrasensitive single-molecule array
Citation: Scrimgeour AG, Condlin ML, Loban A, DeMar JC. Omega-3 Fatty Acids and Vitamin D Decrease Plasma T-Tau, GFAP, and UCH-L1 in Experimental Traumatic Brain InjuryFront Nutr. 2021 Jun 4;8:685220. doi: 10.3389\/fnut.2021.685220. eCollection 2021. PMC8211733

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: ELISA antibody kits, Estimation of GABA and glutamate, Estimation of lipid peroxidation, Estimation of nitrite, High-performance liquid chromatography, Morris water maze, exploration behavior test, forelimb grip strength, method of Ellman, method of Lowry, novel object, open field apparatus
Citation: Rana A, Singh S, Deshmukh R, Kumar A.Pharmacological potential of tocopherol and doxycycline against traumatic brain injury-induced cognitive/motor impairment in ratsBrain Inj. 2020 Jul 2;34(8):1039-1050. doi: 10.1080/02699052.2020.1772508. Epub 2020 Jun 4.10.1080/02699052.2020.1772508

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Behavioral, Western blotting, beam walk, elevated plus maze, forced swim, multi-plex enzyme-linked immunosorbent assay, novel context mismatch, quantitative polymerase chain reaction
Citation: Fraunberger EA, DeJesus P, Zanier ER, Shutt TE, Esser MJ.Acute and Persistent Alterations of Cerebellar Inflammatory Networks and Glial Activation in a Rat Model of Pediatric Mild Traumatic Brain InjuryJ Neurotrauma. 2020 Jun 1;37(11):1315-1330. doi: 10.1089/neu.2019.6714. Epub 2020 Feb 25.10.1089/neu.2019.6714

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Bederson test, Evans blue fluorescence, MRI, Perls staining, TUNEL, Western blot, behavioral, brain water content, enzyme-linked immunosorbent assay, immunohistochemistry, magnetic resonance imaging, myelin basic protein (MBP) expression, quantitative real-time PCR
Citation: Wei L, Zhang J, Zhang B, Geng J, Tan Q, Wang L, Chen Z, Feng H, Zhu G.Complement C3 participates in the function and mechanism of traumatic brain injury at simulated high altitudeBrain Res. 2020 Jan 1;1726:146423. doi: 10.1016/j.brainres.2019.146423. Epub 2019 Oct 22.10.1016/j.brainres.2019.146423

TBI Model Type: Blast model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: HPLC-ECD methods, changes in free amino acid (FAA) concentrations
Citation: Norris C, Weatherbee J, Murphy SF, VandeVord PJ.Neurosci Res. 2024 Jan;198:47-56. doi: 10.1016/j.neures.2023.06.008. Epub 2023 Jun 21.10.1016/j.neures.2023.06.008

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: Biochemical, Chemiluminescence, Histopathological
Citation: Demir D, Kuru Bektaşoğlu P, Koyuncuoğlu T, Kandemir C, Akakın D, Yüksel M, Çelikoğlu E, Yeğen BÇ, Gürer B.Neuroprotective effects of mildronate in a rat model of traumatic brain injuryInjury. 2019 Oct;50(10):1586-1592. doi: 10.1016/j.injury.2019.08.036. Epub 2019 Aug 20.10.1016/j.injury.2019.08.036

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Swiss Webster
Assessments: Neurological severity score, Open-field test, Quantitative RT-PCR, enzyme-linked immunosorbent assay, micro-computed tomography, reverse transcription-polymerase chain reaction
Citation: Zvejniece L, Stelfa G, Vavers E, Kupats E, Kuka J, Svalbe B, Zvejniece B, Albert-Weissenberger C, Sirén AL, Plesnila N, Dambrova M.Skull Fractures Induce Neuroinflammation and Worsen Outcomes after Closed Head Injury in MiceJ Neurotrauma. 2020 Jan 15;37(2):295-304. doi: 10.1089/neu.2019.6524. Epub 2019 Nov 8.PMC696481210.1089/neu.2019.6524

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague–Dawley
Assessments: Hematoxylin-eosin staining, Immunohistochemical staining, Western blotting
Citation: Zhao J, Wang B, Huang T, Guo X, Yang Z, Song J, Zhang M.Glial response in early stages of traumatic brain injuryNeurosci Lett. 2019 Aug 24;708:134335. doi: 10.1016/j.neulet.2019.134335. Epub 2019 Jun 14.10.1016/j.neulet.2019.134335

TBI Model Type: Fluid percussion injury model
Organism Species: rat
Organism Strain: Long-Evans
Assessments: Caspase activity assays, Cavalieri probe method, Conditioned freezing response test, Counting APC-positive cells, Counting NeuN-positive cells, Histology, Immunohistochemistry, Object recognition test, Quantification of TrkA phosphorylation, Western blot analysis, cell counts, immunocytochemistry, kainate sensitivity test, microglia activation, myelin loss, paw placement test
Citation: Delbary-Gossart S, Lee S, Baroni M, Lamarche I, Arnone M, Canolle B, Lin A, Sacramento J, Salegio EA, Castel MN, Delesque-Touchard N, Alam A, Laboudie P, Ferzaz B, Savi P, Herbert JM, Manley GT, Ferguson AR, Bresnahan JC, Bono F, Beattie MS.Brain. 2016 Jun;139(Pt 6):1762-82. doi: 10.1093/brain/aww074. Epub 2016 Apr 15.10.1093/brain/aww074

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Behavioral, Conditioned – Avoidance (CA) test, ELISA, Hematoxylin and Eosin, Histopathological, Nissl staining, Swimming test, Toluidine blue stain, Western blotting
Citation: El-Gazar AA, Soubh AA, Mohamed EA, Awad AS, El-Abhar HS.Morin post-treatment confers neuroprotection in a novel rat model of mild repetitive traumatic brain injury by targeting dementia markers, APOE, autophagy and Wnt/β-catenin signaling pathwayBrain Res. 2019 Aug 15;1717:104-116. doi: 10.1016/j.brainres.2019.04.003. Epub 2019 Apr 16.10.1016/j.brainres.2019.04.003

TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Long-Evans
Assessments: Lesion analysis, Rodent gambling task, rotarod task
Citation: Ozga-Hess JE, Whirtley C, O'Hearn C, Pechacek K, Vonder Haar C.Exp Neurol. 2020 May;327:113217. doi: 10.1016/j.expneurol.2020.113217. Epub 2020 Jan 31.10.1016/j.expneurol.2020.113217

TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Long-Evans
Assessments: Immunohistochemistry, Rodent Gambling Task, lesion analysis
Citation: Shaver TK, Ozga JE, Zhu B, Anderson KG, Martens KM, Vonder Haar C.Brain Res. 2019 Feb 1;1704:103-113. doi: 10.1016/j.brainres.2018.10.004. Epub 2018 Oct 5.10.1016/j.brainres.2018.10.004

TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wistar
Assessments: electron microscopy, morphometric evaluation
Citation: Borges N, Cerejo A, Santos A, Sarmento A, Azevedo I. Changes in rat cerebral mitochondrial succinate dehydrogenase activity after brain traumaInt J Neurosci. 2004 Feb;114(2):217-27. doi: 10.1080\/00207450490249419.

TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: 16S ribosomal RNA gene sequencing, Blood–brain barrier permeability, Enzyme-linked immunosorbent assay (ELISA), Histology, RT-PCR, Western blot, Brain water content, limulus amebocyte lysate assay, Neurological Severity Score (NSS), Rotarod test
Citation: Mirzayan MJ, Klinge PM, Ude S, Hotop A, Samii M, Brinker T, Korkmaz Z, Meyer GJ, Knapp WH, Samii A. Modified calcium accumulation after controlled cortical impact under cyclosporin A treatment: a 45Ca autoradiographic studyNeurol Res. 2008 Jun;30(5):476-9. doi: 10.1179\/174313208X276916.

TBI Model Type: Controlled cortical impact model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Northern blot
Citation: DeKosky ST, Goss JR, Miller PD, Styren SD, Kochanek PM, Marion D.Upregulation of nerve growth factor following cortical traumaExp Neurol. 1994 Dec;130(2):173-7. doi: 10.1006/exnr.1994.1196.10.1006/exnr.1994.1196

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The PRECISE-TBI toolbox are a collection tools and resources to increase rigor and reproducibility with Traumatic Brain Injury within the PRE Clinical Interagency reSearch resourcE - Traumatic Brain Injury (PRECISE-TBI). Please learn more about PRECISE-TBI at https://www.precise-tbi.org

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