On page 10 showing 181 ~ 200 out of 420 results
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Evans blue (EB) extravasation, TUNEL assay, Western blot
Citation: Lu XY, Wang HD, Xu JG, Ding K, Li T.NADPH oxidase inhibition improves neurological outcome in experimental traumatic brain injury.Neurochem Int. 2014 Apr;69:14-9. doi: 10.1016/j.neuint.2014.02.006. Epub 2014 Feb 28.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunocytochemistry
Citation: Liu F, Liao F, Li W, Han Y, Liao D.Progesterone alters Nogo-A, GFAP and GAP-43 expression in a rat model of traumatic brain injury.Mol Med Rep. 2014 Apr;9(4):1225-31. doi: 10.3892/mmr.2014.1967. Epub 2014 Feb 19.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/J6
Assessments: flow cytometry
Citation: Probst C, Mirzayan MJ, Mommsen P, Zeckey C, Tegeder T, Geerken L, Maegele M, Samii A, van Griensven M.Systemic inflammatory effects of traumatic brain injury, femur fracture, and shock: an experimental murine polytrauma modelMediators Inflamm. 2012;2012:136020. doi: 10.1155/2012/136020. Epub 2012 Mar 4.PMC331699810.1155/2012/136020
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Wister
Assessments: ELISA
Citation: DeKosky ST, Goss JR, Miller PD, Styren SD, Kochanek PM, Marion D.Upregulation of nerve growth factor following cortical traumaExp Neurol. 1994 Dec;130(2):173-7. doi: 10.1006/exnr.1994.1196.10.1006/exnr.1994.1196
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Brain water content, Enzyme-linked immunosorbent assay (ELISA), Western blot
Citation: Lu XY, Wang HD, Xu JG, Ding K, Li T.Pretreatment with tert-butylhydroquinone attenuates cerebral oxidative stress in mice after traumatic brain injury.J Surg Res. 2014 May 1;188(1):206-12. doi: 10.1016/j.jss.2013.11.1106. Epub 2013 Dec 1.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL
Assessments: Beam balancing, Beam walk, Immunhistochemical, Round stick balancing, Startle reflex, neurological severity score
Citation: Albert-Weißenberger C, Várrallyay C, Raslan F, Kleinschnitz C, Sirén AL.An experimental protocol for mimicking pathomechanisms of traumatic brain injury in miceExp Transl Stroke Med. 2012 Feb 2;4:1. doi: 10.1186/2040-7378-4-1.PMC330549210.1186/2040-7378-4-1
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: BALB/c
Assessments: Morphometry, Neurobehavioral Evaluation
Citation: Wu Q, Xuan W, Ando T, Xu T, Huang L, Huang YY, Dai T, Dhital S, Sharma SK, Whalen MJ, Hamblin MR.Low-level laser therapy for closed-head traumatic brain injury in mice: effect of different wavelengthsLasers Surg Med. 2012 Mar;44(3):218-26. doi: 10.1002/lsm.22003. Epub 2012 Jan 24.PMC339720310.1002/lsm.22003
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Immunofluorescence staining, Western blot
Citation: Sun LQ, Gao JL, Cui CM, Cui Y, Jing XB, Zhao MM, Wang YC, Tian YX, Wang KJ, Cui JZ.Astrocytic p-connexin 43 regulates neuronal autophagy in the hippocampus following traumatic brain injury in rats.Mol Med Rep. 2014 Jan;9(1):77-82. doi: 10.3892/mmr.2013.1787. Epub 2013 Nov 11.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Motor evaluation, Enzyme-linked immunosorbent assay (ELISA)
Citation: Yang SH, Gangidine M, Pritts TA, Goodman MD, Lentsch AB.Interleukin 6 mediates neuroinflammation and motor coordination deficits after mild traumatic brain injury and brief hypoxia in mice.Shock. 2013 Dec;40(6):471-5. doi: 10.1097/SHK.0000000000000037.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Albino
Assessments: Evans blue dye, Intracranial pressure assessment, Veterinary Coma Scale, blood - brain –barrier permeability, Brain water content
Citation: Khaksari M, Mahmmodi R, Shahrokhi N, Shabani M, Joukar S, Aqapour M.The Effects of Shilajit on Brain Edema, Intracranial Pressure and Neurologic Outcomes following the Traumatic Brain Injury in Rat.Iran J Basic Med Sci. 2013 Jul;16(7):858-64.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: PVG
Assessments: Histology, Enzyme-linked immunosorbent assay (ELISA)
Citation: Vermeij JD, Aslami H, Fluiter K, Roelofs JJ, van den Bergh WM, Juffermans NP, Schultz MJ, Van der Sluijs K, van de Beek D, van Westerloo DJ.Traumatic brain injury in rats induces lung injury and systemic immune suppression.J Neurotrauma. 2013 Dec 15;30(24):2073-9. doi: 10.1089/neu.2013.3060. Epub 2013 Oct 24.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague–Dawley
Assessments: BBB permeability, ELISA, Electron microscopy, Gravimetric analysis, Neurochemical assays, Nissl staining, Western blot analysis, beam-balancing test, immunohistochemistry
Citation: Wang GH, Jiang ZL, Li YC, Li X, Shi H, Gao YQ, Vosler PS, Chen J.Free-radical scavenger edaravone treatment confers neuroprotection against traumatic brain injury in ratsJ Neurotrauma. 2011 Oct;28(10):2123-34. doi: 10.1089/neu.2011.1939. Epub 2011 Sep 27.PMC319136810.1089/neu.2011.1939
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Morris water maze (MWM), qRT-PCR, Immunofluorescence staining, terminal deoxynucleotidyl transferase-mediated dUTP nick 3-end labeling
Citation: Liu S, Zhang L, Wu Q, Wu Q, Wang T.Chemokine CCL2 induces apoptosis in cortex following traumatic brain injury.J Mol Neurosci. 2013 Nov;51(3):1021-9. doi: 10.1007/s12031-013-0091-8. Epub 2013 Aug 11.
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57BL/6
Assessments: Microdialysis in vivo, open field test, Resident-Intruder, Rotarod test, Tactile Allodynia, Tail Suspension Test, Three Chambers Sociability
Citation: Belardo C, Iannotta M, Boccella S, Rubino RC, Ricciardi F, Infantino R, Pieretti G, Stella L, Paino S, Marabese I, Maisto R, Luongo L, Maione S, Guida F. Oral Cannabidiol Prevents Allodynia and Neurological Dysfunctions in a Mouse Model of Mild Traumatic Brain InjuryFront Pharmacol. 2019 Apr 16;10:352. doi: 10.3389\/fphar.2019.00352. eCollection 2019. PMC6476923
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: C57/BL6
Assessments: (wet–dry)/wet brain weight method, Blood–Brain Barrier Permeability, Chronic Brain Tissue Loss, Histochemical, Injured Cell Counts, Morris Water Maze, Nuclear Factor-κB Transcription Factor Assay, Quantitative Real-Time Reverse Transcriptase PCR, Tumor Necrosis Factor-α Enzyme-Linked Immunosorbent Assay, Wire-Grip Test, immunohistochemical, light microscopy
Citation: Khuman J, Meehan WP 3rd, Zhu X, Qiu J, Hoffmann U, Zhang J, Giovannone E, Lo EH, Whalen MJ.Tumor necrosis factor alpha and Fas receptor contribute to cognitive deficits independent of cell death after concussive traumatic brain injury in miceJ Cereb Blood Flow Metab. 2011 Feb;31(2):778-89. doi: 10.1038/jcbfm.2010.172. Epub 2010 Oct 13.PMC304953210.1038/jcbfm.2010.172
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: Balb/c
Assessments: Histological, Immunoblotting, In vivo intestinal permeability assay
Citation: Bansal V, Ryu SY, Blow C, Costantini T, Loomis W, Eliceiri B, Baird A, Wolf P, Coimbra R.The hormone ghrelin prevents traumatic brain injury induced intestinal dysfunctionJ Neurotrauma. 2010 Dec;27(12):2255-60. doi: 10.1089/neu.2010.1372. Epub 2010 Nov 2.PMC330424910.1089/neu.2010.1372
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague-Dawley
Assessments: Lesion Size, Morris Water Maze, Morris water maze, Western Blot Analysis
Citation: Rich NJ, Van Landingham JW, Figueiroa S, Seth R, Corniola RS, Levenson CW.Chronic caloric restriction reduces tissue damage and improves spatial memory in a rat model of traumatic brain injuryJ Neurosci Res. 2010 Oct;88(13):2933-9. doi: 10.1002/jnr.22443.10.1002/jnr.22443
TBI Model Type: Weight-drop model
Organism Species: mouse
Organism Strain: ICR
Assessments: Morris water maze (MWM), Hidden Platform, Novel object recognition (NOR), Y-Maze Test
Citation: Eakin K, Baratz-Goldstein R, Pick CG, Zindel O, Balaban CD, Hoffer ME, Lockwood M, Miller J, Hoffer BJ.Efficacy of N-acetyl cysteine in traumatic brain injury.PLoS One. 2014 Apr 16;9(4):e90617. doi: 10.1371/journal.pone.0090617. eCollection 2014.
TBI Model Type: Weight-drop model
Organism Species: rat
Organism Strain: Sprague‐Dawley
Assessments: behavioural, electrophysiological, histological
Citation: Burns TF, Rajan R.Temporal activity patterns of layer II and IV rat barrel cortex neurons in healthy and injured conditionsPhysiol Rep. 2022 Feb;10(4):e15155. doi: 10.14814/phy2.15155.PMC886444710.14814/phy2.15155
TBI Model Type: Controlled cortical impact model
Organism Species: mouse
Organism Strain: C57BL/6 x SV129
Assessments: Lesion volume, MWM, beam balance, immunohistochemically
Citation: Whalen MJ, Clark RS, Dixon CE, Robichaud P, Marion DW, Vagni V, Graham SH, Virag L, Hasko G, Stachlewitz R, Szabo C, Kochanek PM.Reduction of cognitive and motor deficits after traumatic brain injury in mice deficient in poly(ADP-ribose) polymerase.J Cereb Blood Flow Metab. 1999 Aug;19(8):835-42. doi: 10.1097/00004647-199908000-00002.