Curator Dashboard

Cancer research institute focused on the study of cancer formation and development.

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• RRID
• 1 year ago - submitted by Edyta Vieth

Core specializes in high-throughput CRISPR screening using pooled or arrayed libraries in diverse cellular models. This technology assesses the effects of thousands of genetic perturbations at single-cell resolution with CRISPR knockout (CRISPR KO), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa). It also utilizes base and prime editing to investigate specific mutations, such as those relevant to cancer development and progression.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Core Facility provides technological platforms in the field of light microscopy. A team of highly qualified and experienced professionals supports IFOM's research activities, assisting in sample preparation and acquisition, data post-processing and image analysis.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Core Facility provides technology, instrumentation, and expert support for applications, including Immunophenotyping, Cell cycle and proliferation analysis, Metabolic studies, Apoptosis detection, Fluorescent protein expression analysis, Cytokine, chemokine, and intra/extracellular protein detection.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Specialized laboratory designed for growth, maintenance, and experimentation of living cells under controlled conditions. This facility is used in various fields such as biomedical research, drug development, and supports the culture of primary cells, immortalized cell lines, human-induced pluripotent stem cells (hiPSCs), and organoids, among others.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Core performs routine transmission and scanning Electron Microscopy and all kinds of immune Electron Microscopy, correlative light electron microscopy, three-dimensional EM (3DEM), quantitative stereological evaluation of data and more.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Core focuses on development of innovative biomedical technologies and devices for cancer research as well as biomedical applications using microfabrication and 3D printing.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Facility uses transmission electron microscopy coupled to low angle rotary shadowing to visualize nucleic acids. This technique allows the inspection of the fine ultrastructure of in vivo chromosomal DNA intermediates on properly enriched genomic DNA samples.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Core offers spatial omics processing on many different tissue types. Facility provides instrumnets including Bruker's GeoMx DSP ready for launch with anticipated launch of 10x Visium. Offers expert collaboration from project design to data handoff. Core has established workflows with additional shared resources on UNMC campus to allow for expertise throughout entire project.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Software tool for multi-level visualization of genomic statistical variables on rectangular chromosomes.

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• RRID
• 1 year ago - by Anonymous

Web application provides users with visualization interface to explore and analyze interaction networks between miRNAs and target genes.

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• 1 year ago - submitted by Sarah Overby

Rush University Medical Center is academic medical center for basic and clinical research, with physicians and scientists involved in hundreds of research projects developing and testing the effectiveness and safety of new therapies and medical devices. Offers residency and fellowship programs in medical and surgical specialties and subspecialties.

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• RRID
• 1 year ago - submitted by Edyta Vieth

Core provides full service genomics and Next Generation sequencing. Specializes in microbial sequencing.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Benchtop, high-resolution, spectral imaging instrument that integrates quantitative immunofluorescence and brightfield imaging.

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• RRID
• 1 year ago - by Anonymous

Software tool to project scRNA-seq data into reference single-cell atlases, enabling their direct comparison in stable, annotated system of coordinates. Predicts effects of cell perturbations and identifies gene programs that are altered in different conditions and tissues. Used for interpretation of cell states using reference single-cell maps.

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• RRID
• 1 year ago - by Anonymous

Software R and Python package for comparison and visualization of biological identifiers lists using area-proportional Venn diagrams. Also offers option to map Entrez and/or Affymetrix IDs to Ensembl IDs. In SVG mode, text and numbers can be dragged and dropped. Used to create area-proportional Venn diagram of 2 or 3 circles.

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• RRID
• 1 year ago - by Anonymous

Manually curated database of ferroptosis regulators and ferroptosis-disease associations. There are two secondary categories of ferroptosis regulators: (1) genes and (2) substances. Gene regulators include driver, suppressor, marker, and unclassified regulator. Substances cover range of chemical entities, including pure substances (e.g., iron, erastin) and mixtures (e.g., herbal extracts). Substance regulators include inducers and inhibitors. FerrDb V2 is updated database.

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• RRID
• 1 year ago - by Anonymous

24 channels microscope for incubator with automated remote monitoring of cell cultures. 24 independent cameras are used to acquire brightfield or darkfield scans and perform image analysis of up to 24 wells of cell culture in parallel automatically. Culture quality and data can be checked from PC. It enables real-time, non-invasive, label-free monitoring of cell growth directly inside standard incubators. The system captures time-lapse images and performs automated quantitative analysis, generating dynamic growth curves and detailed cellular behavior profiles.

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• RRID
• 1 year ago - by Anonymous

Cleveland Clinic is renowned for its advancements in cardiac care, including pioneering coronary artery bypass surgery, and its focus on research and education. It's also known for its strong performance in numerous other specialties, including neurosurgery, gastroenterology, and oncology

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• RRID
• 1 year ago - submitted by Edyta Vieth

Core provides biomechanical testing of biological structures and biomaterials. Allows investigators to conduct research of mechanical properties of existing biological structures and constructs, as well as to quantify potential for new technologies and clinical advancements. Robotic simulators are built around the simVITRO software platform and are designed for in vitro simulation of major joints including knee, spine, foot, ankle, hip, shoulder, elbow, wrist and more. Provides testing capabilities for range of biomechanical modalities and will offer expert advice and support for development of new test protocols, innovative techniques for instrumentation and data collection. Modalities include tissues, joints, and multi-articular units, such as foot or spine segments.

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• RRID
• 1 year ago - by Anonymous