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Software R package for calculation and interactive exploration of cell-cell signaling network topologies contained in single-cell RNA-sequencing data. Used to explore cell-cell connectivity patterns based on ligand and receptor data in heterogeneous single-cell datasets.
Software Python toolkit for multi-cellular communication network construction and network analysis of multispecies single-cell and bulk gene expression and proteomic data.
Fully automated IHC/ISH slide staining system with 30 independent slide drawers, single-piece workflow, and capacity for 90 slides/8-hour shift. Automated IHC/ISH slide stainer that handles baking, deparaffinization, and staining. It optimizes laboratory efficiency through continuous access and independent temperature control across its 30 individual slide drawers, supporting a vast library of over 250 ready-to-use assays.
Fully automated slide stainer used in clinical pathology and research laboratories. Automatically processes tissue samples. Uses antibodies to detect and visualize specific proteins or antigens within a tissue sample. Uses labeled DNA or RNA probes to detect and map specific genetic sequences or chromosomal abnormalities within the tissue.
Nanofabrication and characterization facility that provides open access to advanced cleanroom infrastructure, instrumentation, and technical expertise. Offers infrastructure for fabrication and characterization of nanoscale materials, systems and devices. Provides user training, process development assistance, and access to specialized expertise for research and prototyping.
Motorized rotary microtome designed to cut extremely thin, uniform slices of paraffin-embedded tissue samples so they can be mounted on glass slides for microscopic examination and disease diagnosis. Offers three sectioning modes (automated, semi-automated, and manual) and features an automatic electronic brake and an anti-static waste tray for enhanced laboratory efficiency.
Software R package that estimates the distance between cell populations in high-dimensional gene-expression space. Used for identification of perturbed cell types in single-cell RNA-seq data.
Browser-based research platform for life-science labs providing microscopy image analysis, flow cytometry, molecular biology tools, sample tracking, and publication ready figures in one connected workspace.
Software R package to estimate individuals ploidy, aneuploidy and large-scale CNV based on genetic markers. Provides functions for estimating copy number variation (CNV) in individuals using allele intensities or allele count data from high-throughput genotyping platforms, including single nucleotide polymorphism (SNP) arrays and sequencing-based technologies. Provides functions for visualizing results and exporting CNV calls in VCF format.
Software package that takes DArTag Missing Allele Discovery Count (MADC) files with sequential allele IDs and matches the short sequence reads against the current public microhaplotype database. If no match is found, the new allele is appended to the microhaplotype database and assigned a new unique fixed allele ID. If a match is found for an allele already in the microhaplotype database, the sequential allele ID is renamed with the unique fixed allele ID. The output file is an MADC file with globally unique fixed allele IDs.
Core offers proteomics, metabolomics, and lipidomics services.Core specialises in working with precious and low-input samples including single-cell proteomics, deep visual proteomics from FFPE tissue, and integrated multiomics from a single sample. Every project is supported from experimental design through to full bioinformatic analysis and biological interpretation.Proteomics: from bulk expression to single-cell and spatial resolution. Metabolomics: precise identification and isotope tracing of metabolic pathways.Lipidomics: high-accuracy profiling of cellular lipid landscapes and signalling. Speciality: Spatial, Single-Cell and Integrated Multiomics: proteins, metabolites and lipids from the same precious sample.
Core offers services including iPSC reprogramming from blood and skin, iPSC edits, iPSC quality controls, AAV production, lentiviral production, mRNA production, CRISPR design and troubleshooting, consultations on all of the above, courses and training.
Core provides advanced technologies and expert support to study cellular and whole-organism metabolism. The core offers instrumentation for measuring mitochondrial function, metabolic flux, energy expenditure, and metabolite profiling, along with consultation, training, and data acquisition services.
Database contains reference brain atlases for many insect species, neuron morphology when available, repository for published anatomical data, etc. Provides insect neuroanatomical and functional data.
Software Python package and command-line tool for merging, comparing, and translating genome-scale metabolic models.
Benchtop centrifugal evaporator used in laboratories to remove solvents from samples. It is used in drug discovery, chemistry, and life science research to concentrate liquids or dry samples completely without damaging them.
Software R package to quantify the activity of signatures of chromosomal instability from absolute copy number profiles. Used to quantifying copy number signatures from absolute copy number profiles.
Software application as implementation of ASCAT allowing generation of CNV profiles from single cell and short coverage sequencing data.
Software toolbox (FMUT) is an extension to David Groppe’s Mass Univariate ERP Toolbox (MUT). MUT implements t-tests for several different mass univariate approaches to the analysis of ERP data. FMUT adds to this by implementing one-way and factorial ANOVA versions of the same mass univariate approaches.
Equipment capable of producing the proper negative phase and secondary shock patterns of a free field explosion. Stumptown Research & Development, LLC is licensed as the sole manufacturer of the Advanced Blast Simulator (Patent US20130042665A1) which represents the state of the art in blast wave generation.The ABS is fully customizable to meet any experimental needs including biomedical research and structural testing. The design can be modified to fit within your existing laboratory allowing for repeatable, accurate results in a controlled environment.