Curator Dashboard

Next-generation, high-throughput liquid chromatography (LC) separation platform designed to standardize and accelerate mass spectrometry (LC-MS) based proteomics. Processes up to 500 samples per day. Includes standard and high sensitivity (Whisper Zoom) methods designed for consistency, allowing non-experts to run analyses with minimal training.

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• 1 month ago - by Anonymous

Software TypeScript library for decoding, inspecting, processing, and converting ordinary images and scientific rasters in Node.js and modern browsers. It provides readers for microscopy, whole-slide pathology, medical imaging, electron microscopy, spectroscopy, hyperspectral, and multidimensional array formats, including OME-TIFF, OME-Zarr, Aperio SVS, DICOM, NIfTI, MRC/CCP4, NRRD, DigitalMicrograph, EMD, ENVI, and FITS. Range-backed readers can request selected regions, tiles, volume planes, and metadata while preserving native numeric samples where supported. The default package has no runtime dependencies.Low-memory, zero-dependency image codecs and processing in pure TypeScript for Node.js, browsers, and serverless runtimes.

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• 1 month ago - by Anonymous

Core provides vision researchers with confocal, multiphoton, and macroview fluorescence microscopy together with histology services. Instrumentation includes Olympus FV1200 and FV1000 confocal systems, an Olympus FV1000-MPE multiphoton laser scanning microscope, an Olympus MVX10 macroview fluorescence system for bright-field and fluorescence imaging of flat mount tissues such as retinas and corneas, a Leica cryostat for sectioning, and Nikon E400 and E800 microscopes with dedicated review stations. Histology services include block cassettes, and special staining, and unstained sections.

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• 1 month ago - submitted by Adrian Filiberti

Core provides vision researchers with in vivo imaging and functional analysis of visual system disease models, using instrumentation comparable to that used in clinical ophthalmology so that findings in animal models translate to human disease. Instrumentation includes Diagnosys electroretinography systems, Bioptigen SD optical coherence tomography, optokinetic tracking, Micron III and IV imaging systems with slit lamp and laser attachments, Zeiss operating microscopes with imaging, and specialized environmental housing including dark adaptation, dark rearing, and light damage. The core operates at two campus locations and also provides genotyping services for transgenic and mutant mouse and chick strains.

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• 1 month ago - submitted by Adrian Filiberti

Shared high-performance computing (HPC) system used to run large-scale data science, scientific simulations, and heavy computational research. Used for processing massive data sets and running complex statistical or machine learning models using tools like Jupyter Notebooks, R, and Python.

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• 1 month ago - submitted by Peter Higbee

AI-powered cloud platform for computational drug discovery. Integrates molecular docking (AutoDock Vina, GNINA), GPU-accelerated GROMACS molecular dynamics simulation, ADMET prediction, QSAR modeling, and AI research intelligence. Free tier available

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• 1 month ago - submitted by Tajuddin Shaik

Global life sciences company that breeds and supplies laboratory research animals (primarily rodents) and related services to pharmaceutical, government, and academic institutions. It was acquired by Inotiv in November 2021 to expand its nonclinical drug discovery and research product capabilities. Provides laboratory research models (such as specialized and genetically engineered mice and rats). Supplies animal diets, bedding, and testing services for biomedical research.

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• 1 month ago - submitted by Edyta Vieth

Core provides histopathology services and expertise with human tissue and other species tissues. Offers pathology expertise and infrastructure that allows researchers to perform state-of-the-art spatial biology, cellular, molecular, quantitative and computational pathology analyses. Provides support from project design through downstream analysis. Services include paraffin and frozen tissue processing, embedding, sectioning along with routine and special histological stains, tissue microarray (TMA) creation, immunohistochemistry (IHC) and in situ hybridization (ISH) services, imaging (Aperio, Nuance, Vectra, PhenoImager HT2) and image analysis using HALO/HALO AI and InForm software, human cell line authentication and, spatial and molecular profiling (10X Genomics Visium/Xenium, NanoString GeoMx and nCounter).

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• 1 month ago - submitted by Karla Esbona

Provides mice and related rodent models through the Laboratory Animal Sciences Program (LASP), housing thousands of research models and managing specialized cores. Maintains and supplies genetically engineered mouse models (GEMMs) and specialized cancer models for research. Provides germ-free, axenic, and microbiome-defined mouse lines. Offers services like CRISPR-Cas9 genome modification, IVF, strain rescue, and sperm/embryo cryopreservation.

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• 1 month ago - submitted by Edyta Vieth

NIG-Fly Stock Center at the National Institute of Genetics in Japan is a major international repository that collects, maintains, and distributes Drosophila melanogaster (fruit fly) genetic strains. It provides researchers worldwide with specialized mutant and transgenic lines including extensive RNA interference (RNAi) and CRISPR knockdown libraries used to study gene function and human diseases.

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• 1 month ago - submitted by Edyta Vieth

Biological database and resource center for Drosophila melanogaster (fruit fly) genetics. It hosts a comprehensive library of roughly 4,000 transgenic UAS-ORF strains designed for in vivo gene overexpression screening and functional genomics research.

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• 1 month ago - submitted by Edyta Vieth

Core provides instrumentation and expertise for single-cell analysis in models of ocular development, degeneration, infection, and inflammation. Instrumentation includes a Cytek Aurora full-spectrum flow cytometer, a Cytek Aurora CS cell sorter, and a Luminex 200 multiplex suspension array system, together with an Agilent wound scratch tool, an Agilent Lionheart XL plate imager, and a CellZScope for real-time barrier physiology. Services include assisted and independent instrument use, training, panel and experiment design, sample preparation, and data analysis, with particular expertise in high-autofluorescence ocular tissues.

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• 1 month ago - submitted by Adrian Filiberti

Biomedical and Obesity Research Core (BORC) is a shared research facility providing specialized instrumentation, technical expertise, and research services. BORC supports metabolic phenotyping, cellular and molecular analysis, imaging, extracellular vesicle and nanoparticle characterization, animal behavior and physiology, and other specialized research applications. Provides access to specialized equipment and offers both staff-assisted services and user-operated instrumentation.

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• 1 month ago - submitted by Edyta Vieth

Core provides proteomics services including Protein identifications, PTM analysis, quantitative proteomics (label-based and label-free).

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• 1 month ago - submitted by Edyta Vieth

Transgenic Facility provides services: CRISPR reagent design, Zygote and Cell Microinjection,Embryo Transfer, Embryo/Sperm Cryopreservation, IVF/Embryo thaw for line recovery and importation.

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• 1 month ago - submitted by Edyta Vieth

Core at BIDMC is a physical biorepository of deeply phenotyped human specimens that are linked to clinical diagnoses, a digital databank of omics and histological profiling generated from stored and annotated samples, and a virtual catalogue interface that will facilitate collaborations with the aim to catalyze innovative biomedical research and discovery. Goal of the BioDataBank Core is to build a biobank of Beth Israel Deaconess Medical Center (BIDMC)/BILH patient biospecimens & Omics data from our four Translational Research Hubs that are linked to clinical data for biomedical research directed towards advancing precision medicine. We will diversify the targeted biobank populations by engaging and collaborating with Beth Israel Lahey Health (BILH)-associated community health centers.

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• 1 month ago - submitted by Edyta Vieth

Core supports the BILH i2b2 system, which enables investigators to query and download clinical data on more than 7 million patients across all BILH hospitals.

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• 1 month ago - submitted by Edyta Vieth

Core works in conjunction with Harvard Catalyst to provide statistical and epidemiological support for investigators throughout Beth Israel Deaconess Medical Center.

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• 1 month ago - submitted by Edyta Vieth

Software R package for the statistical identification and removal of contaminant sequences in marker-gene (e.g. 16S rRNA) and metagenomics sequencing data. Implements frequency- and prevalence-based contaminant identification methods. Used for simple statistical identification and removal of contaminants in marker-gene and metagenomics sequencing data.

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• 1 month ago - by Anonymous

Software R package provides ggplot2 extension that colors scatter plot points by their neighbor count. It solves overplotting in large datasets by showing data density through color while keeping individual points and outliers visible.

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• 1 month ago - by Anonymous