We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Browser based collection of peptide calculation tools. It includes calculators for peptide molecular weight (average molecular weight, monoisotopic mass, molecular formula and mass-to-charge ratios), net charge and isoelectric point, solution concentration, dilution, reconstitution and peptide blends. The site also provides mass, volume and U-100 syringe-unit conversions from user-supplied inputs.
Software Python command-line tool for auditing control-associated prediction in pooled variant-effect screens. Starting from prepared residue-level and variant-condition matrices, it provides matched prediction with and without control features, direction-level predictive attribution, rank-aware representation geometry, partition comparisons, and equal-feature predictability scoring. Outputs include split-level results, execution parameters, and checksums.
Located on the 3rd floor of the Life Science Laboratory on the University of Massachusetts Amherst campus core provides services and resources for conducting research with human subjects. The CH2P has service lines supporting clinical sample collection, physiological, biomechanical, neuromechanical, and behavioral research.
Software R package designed to work with pre-normalized data derived from Reverse Phase Protein Arrays (RPPA), downstream of RPPASPACE. Provides a compendium of functions related to analytical pipelines with graphical visualization and figure generation.
Interactive web application for exploring Dictyostelium gene expression. Provides curated bulk RNA-seq developmental time courses and a developmental single-cell RNA-seq time course of wild-type AX4 and cAMP-signalling mutants. Coordinated modules (expression time courses, differential expression, hierarchical clustering, Gene Ontology enrichment and an interactive UMAP workspace) share one gene selection, and analysis sessions can be bookmarked and exported.
Core offers imaging services including design, build, upgrade, and repair optical systems. Provides high-throughput, automated, and custom-built imaging infrastructure and open-source optical tools for neuroscience and biological research. Services include Automated Whole-Brain Imaging, Histology and Spatial Transcriptomics, In-Vivo Microscopy Technical Services.
glmtrust is an open-source Python package for auditing comparisons of variant effect predictors, or any scorers, that decline to score some inputs. For each scorer on a labelled panel it reports reach (the share of variants it scores, by class), its AUROC on the pairs it scores, pair coverage, the must-answer AUROC that charges every declined pair at one half, and sharp partial-identification bounds on the AUROC it would reach had it scored every variant; it then reports which pairwise comparisons those bounds can decide. A second layer turns a score into a calibrated probability, a conformal prediction set and a selective call that abstains when the model is not confident. It accompanies the GigaScience article 'Auditing variant effect predictor comparisons for missing scores: a reach resource for 49 predictors and nine amniote species'.
Core provides services to uncover the molecular functions and interactions of proteins, mass spectrometry instrumentation, expertise and guidance from experimental design to data interpretation.
Contains statistical data showing how often specific combinations of Human Leukocyte Antigen (HLA) genes (called haplotypes) appear within different racial and ethnic groups in the massive database managed by the National Marrow Donor Program (NMDP). High-resolution HLA alleles and haplotypes in the U.S. population.
Open database of U.S. dental care prices and Medicaid dental payments. It publishes Medicaid amounts paid per claim line by CDT procedure code and state for 2018-2024, derived from the HHS/CMS T-MSIS provider spending file; state Medicaid dental fee schedules with links to each source document and a checksum; and cash-price ranges for 12 common procedures across 51 U.S. state markets. Data are served as static JSON with no key (CC BY 4.0), documented with an OpenAPI 3.1. Intended for health services research and health economics.
Software Rust-first research simulation library for deterministic discrete-event simulation and agent-based modeling, with ECS-style state, deterministic random streams, replay/conformance fixtures and polyglot binding previews. It is an active pre-release project; stable APIs and registry publication remain subject to its release gates. DES/ABM simulation engine with ECS state, conformance fixtures, docs, and polyglot binding previews.
Funding programs that Cornell offers to help researchers across all fields pursue new ideas and important projects. These grants provide critical support for creative, interdisciplinary work; emerging areas of study; and more. Research and Innovation Support from Cornell University.
Software R package provides prebuilt database of human gene and transcript genomic coordinates based on the hg38 (GRCh38) genome assembly from the UCSC KnownGene track. Exposes an annotation databases generated from UCSC by exposing these as TxDb objects.
Software flexible toolset for somatic mutation enrichment analysis of tumor whole genomes. Somatic coding and non-coding mutation enrichment analysis for tumor WGS data.
Software application that calculates indices and fits of temporal frequency responses. It calculates indices directly from empirical measurements without fitting and provides tuning curves using Difference-of-Gaussians and Movshon fits, along with fit parameters and associated indices.
Software application that calculates the contrast sensitivity of a neural element as a function of spatial frequency. It derives contrast sensitivity from parameters of contrast tuning curves provided as input.
Software application that calculates spatial frequency response fits and indices. It calculates fitless indices directly from empirical measurements and calculates spatial frequency tuning curves along with fit parameters and associated indices using Difference-of-Gaussians and Movshon fits.
Software application for gene editing, protein design, and project management.
Curated, open-access repository integrating publicly available transcriptomic data for Prunus dulcis and related stone-fruit species. Transcriptomic resource for almonds (Prunus dulcis).
High-speed, automated, whole slide imaging system designed to digitize standard glass slides (26 mm × 76 mm) into high-resolution, high-definition digital data. It features Time Delay Integration (TDI) sensor technology with a 3-chip TDI camera for superior color reproduction. The system supports high-throughput automatic batch processing for up to 210 glass slides and offers 20× and 40× magnification modes with dynamic pre-focusing and z-stack capability for thick samples.