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Proteomics Facility is the centralized service unit of the Medical Faculty of RWTH Aachen University for the analysis of proteome samples. Offers sample preparation and mass spectrometric analysis, as well as bioinformatic processing of raw data (identification and quantification) of peptides and proteins, along with functional bioinformatic analysis of the resulting datasets.
Core provides Next Generation Sequencing (NGS) expertise and services including nucleic acid sample extraction, quantification, RT-qPCR and Quality Control (QC), experimental design, advanced data analysis.
Core facility provides genome editing services in vitro and in vivo for translational cancer research. Services span functional genomics (CRISPR screens across cells, organoids and patient-derived xenograft models, integrated with single-cell RNA sequencing), transgenics (embryo manipulation, pronuclear injection, electroporation, cryopreservation, and import/export of genetically modified models), and multimodal pre-clinical trials run through a dedicated Small Animal Hospital using genetically engineered, xenograft and orthotopic models. Offers experimental design consultation to match editing technologies to each research question.
Ocular service platform and research company launched by Topcon Healthcare. Provides researchers with ethically sourced, de-identified real-world datasets and clinical trial data for artificial intelligence (AI) and digital health innovation. Primary service is providing AI-ready datasets (such as retinal images, visual function metrics, and EMRs). Access to these databases is generally not a direct "consumer free" service; rather, researchers and sponsors must navigate a structured application and review process overseen by an independent Data Access and Governance (DAG) committee. While IDHea aggregates clinical screening data from routine optometry visits, the patient-facing eye imaging itself is usually part of standard care.
Core is multi-user and service laboratory that offers comprehensive genetic and genomic services. Provides expert consultation, grant application support, training, and both standard and customized sequencing library preparation. Collaborates on genomics, transcriptomics and epigenomics projects.
Core offers research instrumentation for hands-on use to researchers. Provides molecular biology, analytical, and imaging instruments to serve RI’s biomedical scientists totaling 3800 sq. ft. in the URI College of Pharmacy building.
System enables precise recording and stimulation of electrogenic cells across multiple wells, combining single-cell sensitivity with scalable experimental capacity. MaxTwo captures electrical activity from individual cells and complex networks with high precision, allowing scientists to detect even the smallest action potentials. This accelerates data collection and deepens insight into cellular function. Used in neuroscience and drug discovery. It features thousands of microscopic sensors embedded in culture plates that record the electrical activity (action potentials) of living cells, such as neurons and heart cells, at single-cell and subcellular resolutions.
Software R package to provide simple and uniform way of evaluating R expressions asynchronously using various resources available to the user. Unified parallel and distributed processing in R for everyone.
Software tool to combine purrr’s family of mapping functions with future’s parallel processing capabilities.
Core facility provides technical services including transgenic breeding, chemical carcinogenesis treatment, tumourigenicity studies in nude mice and quarantine facilities to allow the import of animals from both Europe and other countries.
Software tool that ingests datasets from diverse knowledge bases and transforms them into modular, interoperable knowledge graphs.
Spectrophotometer to rapidly quantify and assess the purity of extremely small biological samples (like DNA, RNA, oligonucleotides, and proteins). It has a patented, maintenance-free sample port that allows you to measure sample volumes as small as 0.5 μ L to 1 μ L without needing a cuvette. In addition to the micro-volume port, it includes a standard 10 x 10 mm cuvette port. This allows for traditional spectrophotometry uses like enzyme kinetics, cell density (OD600) measurements, or assays requiring larger volumes.
Compact, filter-based laboratory instrument used to measure the optical density (absorbance) of solutions in standard 6- to 96-well microplates. It is primarily used for running ELISA assays, enzyme activity projects, and general life science research. Detection Mode: Absorbance-only (UV-Vis). Accommodates 6-, 12-, 24-, 48-, and 96-well plates (with specialized NB models supporting 384-well plates).
Software Rust library with Python bindings for bounded-memory, near-real-time preprocessing of high-density (Neuropixels-scale) extracellular electrophysiology recordings. It streams bandpass filtering, common median referencing, and whitening one chunk at a time with the Python Global Interpreter Lock released, bounding peak memory by chunk size rather than recording length.
Multi-organism database containing interactions and roles of proteins in inter- and intracellular signaling and transcriptional and post-transcriptional regulation.
Software R package to detect empty droplets, damaged, and intact cells, and accurately distinguish them from one another. Identification of empty droplets and damaged cells in scRNAseq data.
Software R package for fast Wilcoxon rank sum test and auROC analysis.
Software tool as linear mixed-effects model estimation algorithm. Single-cell differential expression analysis using linear mixed-effects models.
Web browser-based platform for multiplexed imaging and spatial transcriptomics. Used for interactive discovery of spatial biology at scale.
Software toolkit for processing multiplexed tissue images. Used for multiplexed tissue image processing and analysis that integrates previously developed computational tools.