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Core offers full histology services including processing and embedding, cutting, staining, and immunohistochemistry. Our services can be customized to fit the needs of any research program.
Microplate reader designed for academic, clinical, and industrial laboratories to detect light-emitting or absorbing markers with Manufacturer/Brand: PerkinElmer (formerly Wallac Oy). It supports over 10 non-radioactive technologies, including fluorescence, luminescence, time-resolved fluorometry, and absorbance in various plate formats (1-864 wells). Accepts microtitration plates (up to 1536 wells), Petri dishes, slides, and filters.Equipped with shaking, scanning, and optional temperature control/liquid dispensers for kinetic studies. Operates as a stand-alone unit or integrates with robotic systems for high-throughput screening.
Core to accelerate scientific discovery in G protein-coupled receptors (GPCRs) physiology and pharmacology. Provides services to identify signal transduction processes that are specific to their GPCR of interest (such as opioid, cannabinoid and muscarinic) that is either natively present or expressed heterologously in cell systems. Assists investigators with drug development studies. Support researchers with assay development and optimization, pilot data, and grant assistance. Houses instrumentation used.
Competitive enzyme-linked immunosorbent assay (ELISA) kit for quantitative determination of testosterone concentration in serum, plasma and other biological fluids. Manufactured by ELK Biotechnology. Catalog number ELK10254.
Benchtop instrument designed for life science research, specifically for imaging, detecting, and quantifying protein and nucleic acids on gels and blots. It enables multi-channel analysis, including laser infrared (IR) fluorescence, RGB visible fluorescence, and chemiluminescence, allowing for multiplexed Western blots.
Software tool for reconstruction of higher order chromatin from scRNA-seq and scATAC-seq. Chromatin compartment inference from single-cell RNA- and ATAC-seq.
Data resource for clinical transcriptomes with cancer treatment response, and meanwhile supports various data analysis functions, providing insights into the molecular determinants of drug resistance. CTR-DB 2.0 is updated cancer clinical transcriptome resource, expanding primary drug resistance and newly adding acquired resistance datasets and enhancing the discovery and validation of predictive biomarkers.
Software tools for parsing measurement with threshold over time data (eg tumour treatment studies) and generating interactive and static plots.
Software pipeline for dissecting glioblastoma risk signatures in the tumor immune microenvironment based on single-cell, bulk, and spatial transcriptomic data.
Software pipeline for identifying enhancers in bulk or single-nucleus ATAC-seq and multiomic data with a high degree of accuracy for prioritizing testing of promising candidate cell type enhancers for targeting homologous cell types across mammalian species.
Core enables generation of genetically defined human iPSC-derived hepatocytes, CRISPR/Cas9 mediated gene editing, and primary mouse hepatocyte isolation.
Software data-centric, backend-agnostic framework for zero-shot cell-type annotation. Data-centric marker distillation for zero-shot cell-type and spatial annotation with LLMs.
Software Python library for spatial analysis of histological brain section images using a reference brain atlas. Implements the core quantification algorithms from the QUINT workflow, designed to replicate and extend the Quantifier feature of the Nutil software.
Software tool is revision of classic ilastik. Used for interactive (supervised) pixel-level image classification and segmentation.
Software code for simulating diffusion in brain extracellular space images.
Software code for Monte Carlo diffusion simulation. Monte Carlo diffusion with reflecting or absorbing obstacles in 2 and 3D.
Machine-readable framework designed to standardize, organize, and annotate the anatomical structures, developmental stages, and spatial relationships of the human brain during development. It is primarily derived from the Allen Developing Human Brain Atlas (BrainSpan) to provide a structured, hierarchical taxonomy for researchers. Application ontology built by combining ontologised versions of the Allen Institute Developing Human Brain Atlas (DHBA) StructureGraph mapped to Uberon.
Software hepatocyte ploidy identification pipeline on the stereo-cell platform for accurate liver polyploidy classification via fluorescence staining and deep learning tools.
SMIntegration is an innovative open-source platform for integrated analysis of spatial transcriptomics and metabolomics data. It integrates spatial pattern recognition, differential comparison, network construction, and functional annotation into a unified workflow. Designed to address key challenges in spatial multi-omics correlation analysis, SMIntegration enables researchers to explore gene-metabolite co-regulation mechanisms through an intuitive web interface, revealing spatial heterogeneity in tissue development and disease progression.