Curator Dashboard

Software Phyton tool for genome-scale metabolic model reconstruction. Used for reconstruction of species and community level metabolic models.

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• RRID
• 2 months ago - submitted by David James Sherman

A high level patient-centric ontology for the pharmaceutical industry. The ontology should enable silos in discovery research, hypothesis management, experimental studies, compounds, formulation, drug development, market size, competitive data, population data, etc. to be brought together. This would enable scientists to answer new questions, and to answer existing scientific questions more quickly. This will help pharmaceutical companies to model patient-centric information, which is essential for the tailoring of drugs, and for early detection of compounds that may have sub-optimal safety profiles. The ontology should link to existing publicly available domain ontologies.

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• SciCrunch
• 13 years ago - by Anonymous

Provides optical and electron microscope infrastructure for live cell imaging, multi photon imaging, advanced sample preparation including cryo-preparation for electron microscopy, routine SEM and TEM, Cryo-TEM, TEM tomography, and Correlative Light and Electron Microscopy (CLEM). Equipped with 4 electron microscopes (1 SEM and 3 TEMs), 2 advanced fluorescence microscopes (confocal/multi-photon and spinning disk), cryo-fixation (High pressure freezer, Vitrobot) and EM processing equipment (Microwave, critical point dryer, coaters).Provides microscopy access, training and service.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Core provides investigators with data acquisition and management, advanced biostatistical modeling, and secure high-performance computing (HPC) infrastructure. Provides researchers with tools they need to successfully conduct rigorous, impactful population health research in rural and frontier communities.

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• RRID
• 2 months ago - by Anonymous

Software package, written in Matlab (Mathworks, Natick, MA), providing tools to automatically reconstruct neuronal branching from microscopy image stacks and to generate synthetic axonal and dendritic trees. It provides the basic tools to edit, visualize and analyze dendritic and axonal trees, methods for quantitatively comparing branching structures between neurons, and tools for exploring how dendritic and axonal branching depends on local optimization of total wiring and conduction distance.

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• SciCrunch
• 13 years ago - by Anonymous

Facility uses MiCores/iLab to schedule time on microscopes.Allows scientists to study form and function of biological machines that are too large to study using X-ray crystallography. Provides instruments and faculty expertise specializing in cryo electron microscopy.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Core provides research infrastructure, data resources, and analytical expertise to support studies in sex-based precision medicine. Facilitates access to and analysis of large-scale clinical, electronic health record, genomic, and population datasets, including eMERGE and the All of Us Research Program, and assists investigators with their own research data. Core provides expertise in biomedical informatics, biostatistics, statistical genetics, bioinformatics, data management, artificial intelligence and machine learning, and implementation science. Through consultation and collaborative support, the SPMRC assists investigators with study design, data acquisition and management, analytical approaches, interpretation of results, and development of rigorous, reproducible research addressing sex differences in health and disease.

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• RRID
• 1 month ago - by Anonymous

EVEX is a text mining resource built on top of PubMed abstracts and PubMed Central full texts. It contains over 40 million bio-molecular events among more than 76 million automatically extracted gene/protein name mentions. The text mining data further has been enriched with gene normalization results, allowing straightforward integration with external resources. Further, gene families from Ensembl and HomoloGene provide homology-based event generalizations. EVEX presents both direct and indirect associations between genes and proteins, enabling explorative browsing of relevant literature.

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• SciCrunch
• 12 years ago - by Anonymous

Provides core laboratory support, technical consultation, assistance with experimental design and data analysis for investigators using high throughput genomic sequencing, genotyping and gene expression in their research programs.Provides support for RNA-Seq, ATAC-seq, ChIP-Seq, Single Cell RNA-seq, Spatial Transcriptomics, Exome/Genome sequencing, Whole Genome and Reduced Representation Bisulfite Sequencing (WGBS, RRBS), 16S rRNA Sequencing, Small RNA-Seq, Metatranscriptomics, qRT-PCR, processing of RNA/DNA, as well as custom applications and approaches. Bioinformatic analysis support is also available.

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• SciCrunch
• 14 years ago - by Anonymous

Core supports the BILH i2b2 system, which enables investigators to query and download clinical data on more than 7 million patients across all BILH hospitals.

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• SciCrunch
• 1 month ago - submitted by Edyta Vieth

Established in 1980, the Life Extension Foundation is a nonprofit organization, whose long-range goal is to radically extend the healthy human lifespan by discovering scientific methods to control aging and eradicate disease. The largest organization of its kind in the world, the Life Extension Foundation has always been at the forefront of discovering new scientific breakthroughs for use in developing novel disease prevention and treatment protocols to improve the quality and length of human life. Through its private funding of research programs aimed at identifying and developing new therapies to slow and even reverse the aging process, the Life Extension Foundation seeks to reduce, and ultimately eliminate, such age-related killers as heart disease, stroke, cancer and Alzheimer''s disease. Long-time members are keenly aware of the scientific research that Life Extension Foundation funds to develop validated methods to slow and reverse the aging process. Less known is Life Extension''s multi-prong program to develop safer and more effective cancer therapies. One reason we focus so heavily on cancer research is that this dreaded disease represents a roadblock in our ability to develop effective means to combat aging.

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• SciCrunch
• 16 years ago - by Anonymous

Provides NGS services for research and clinical samples in CLIP and CAP accredited laboratory.Services include consultation, sample processing, sequencing and data analysis , as well as interpretation and reporting.Service support for genomics based applications including experimental design, bioinformatics, development of novel assays, grant writing and manuscript preparation. We are experienced in broad range of biological disciplines including basic biology, infectious diseases, cancer, neurobiology, immunology and clinical research. Clinical Genomics lab has extensive experience in molecular diagnostics and clinical research, and specializes in clinical biomarker discovery, validation and diagnostic test development.

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• SciCrunch
• 5 years ago - submitted by Edyta Vieth

Software R package for computation of adjusted rand-index and other such scores. Used for efficient computations of standard clustering comparison measures.

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• RRID
• 1 month ago - submitted by Zhenhao Shi

The Museum of Comparative Anthropogeny (MOCA) is a collection of comparative information regarding humans and our closest evolutionary cousins (chimpanzees, bonobos, gorillas and orangutans i.e, great apes), with an emphasis on uniquely human features. MOCA is organized by Domains, each grouping Topics by areas of interest and scientific discipline. Each topic entry will eventually cover existing information about a particular difference (alleged or documented) between humans and non-human hominids. Comparisons of these non-human hominids with humans are difficult, as so little is known about their phenotypic features (phenomes), in contrast to humans. Ethical, fiscal and practical issues also limit collection of further information about great apes. MOCA attempts to collect existing information about human-specific differences from great apes, currently scattered in the literature. Having such information in one location could lead to new insights and multi-disciplinary interactions, and to ethically-sound studies to explain differences, and uniquely human specializations. MOCA is not targeted at experts in specific disciplines, but rather aims to communicate basic information to a broad audience of scientists from many backgrounds, and to the interested lay public. MOCA includes not only aspects wherein there are known or apparent differences between humans and great apes, but additionally, topics for which popular wisdom about claimed or assumed differences is not entirely correct. It is for all these reasons that MOCA is called a Museum, and not an Encyclopedia or Database.

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• SciCrunch
• 16 years ago - by Anonymous

Software tool for prediction of lysine acetyltransferase specific modification sites from protein sequences.

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• RRID-Legacy
• 5 years ago - submitted by Jiayi Wan

Core offers guidance, collaboration, and services in animal models and in vivo imaging for cancer research. Provided services include consultation on experimental design, patient-derived xenograft implantation services, treatment and tumor monitoring, in vivo imaging, humanized mouse models, and training in support of cancer research employing animal models.

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• RRID
• 1 month ago - by Anonymous

Dictyostelium discoideum is a great organism to use to teach cellular biology. It exhibits very interesting behaviors, such as chemotaxis and phagocytosis, that can readily be studied in standard laboratories without the need for expensive equipment. Lists of labs being used in real courses settings and all necessary information for performing those experiments are provided. Major headings: * Dictyostelium cell biology course, by Dr. David Knecht, University of Connecticut * Dictyostelium cell biology, by Dr. Derrick Brazill, Hunter College, New York * Report on the number of cells in a slug, contributed by John Bonner * Practical on chemotaxis, by Dr. Thierry Soldati, University of Geneva * Comments from Researchers * References suggested by contributors

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• SciCrunch
• 16 years ago - by Anonymous

Software annotation tool for audio and video recordings. Annotation can be sentence, word or gloss, comment, translation or description of any feature observed in media. Annotations can be created on multiple layers. Tiers can be hierarchically interconnected. Annotation can either be time-aligned to media or it can refer to other existing annotations. Content of annotations consists of Unicode text and annotation documents are stored in XML format (EAF).

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• RRID-Legacy
• 5 years ago - by Anonymous

Core for advanced materials characterization, micro/nanoscale manufacturing, and bioengineering research. NERCF provides open access to more than 20 state-of-the-art research instruments, technical consultation, user training, and collaborative research support for investigators from academia, government laboratories, industry, and external institutions. Major capabilities include scanning electron microscopy, focused ion beam, X-ray computed tomography, metal additive manufacturing, atomic force microscopy, nano-IR spectroscopy, optical profilometry, and mechanical characterization. By integrating advanced manufacturing with multimodal characterization, NERCF supports interdisciplinary research, workforce development, and innovation across Nebraska and beyond.

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• SciCrunch
• 3 weeks ago - submitted by Edyta Vieth

Evaluates disease-causing potential of sequence alterations.

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• SciCrunch
• 13 years ago - by Anonymous