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Specialized biotechnology company that provides histology services, molecular pathology services, and specialized research reagents to accelerate biomedical research. They assist scientists in academia and industry with tissue preparation, immunostaining, 3D cell culture processing, and laser capture microdissection (LCM) for cancer, neuroscience, and drug development studies.
Offers guidance and support from the very beginning of project development to data analysis. Offers hands-on, personalized support throughout experimental process including experimental design, instruments training to develop microscopy skills.
Independent, non-profit research institution closely affiliated with MIT, with many of its members holding faculty positions in the MIT Biology Department. Dedicated to improving human health through basic biomedical research.
Provides flexible, cost-efficient clinical research coordinator support across disease areas and disciplines at the University of Pittsburgh. Offers full-service or targeted, as needed support. Services include study start up, regulatory assistance, budgeting and contracting, participant recruitment and enrollment, study visit conduct, data and query management, safety oversight, blood draws, and study closeout, as well as coordinating or participating center roles for multi-site trials. CRConnect can deploy highly experienced coordinators for only the services or amount of time required, reducing costs and providing coverage for investigators without full time staffing needs. The team supports a wide range of clinical research across Pitt and UPMC systems, including IND trials (Phase I–IV), multi center studies, IDE trials, interventional and observational studies, and collaborates closely with other Pitt and UPMC shared resources to ensure investigators are directed to the appropriate support.
Software tool designed for mapping Quantitative Trait Loci (QTLs), particularly expression QTLs (eQTLs), by identifying statistical associations between genetic variants (genotypes) and molecular phenotypes (e.g., gene expression levels). Used in large-scale functional genomics projects, such as GTEx, to connect specific genetic variants to phenotypic variation. GPU-enabled QTL mapper, achieving ~200-300 fold faster cis- and trans-QTL mapping compared to CPU-based implementations.
Software end-to-end framework for perturbation analysisis. Ecosystem framework for analyzing large-scale single-cell perturbation experiments.
Software tools for correcting single cell barcodes for various scATAC-seq techniques and creating fragment files and spltting BAM files per cluster.
Software R package enables differential expression analysis on multi-sample single cell datasets using linear (mixed) models with precision weights.
Software application for rapid relatedness estimation for cancer and germline studies using efficient genome sketches extract informative sites, evaluate relatedness, and perform quality-control on BAM/CRAM/BCF/VCF/GVCF. Used for rapid relatedness estimation for cancer and germline studies using efficient genome sketches.
File format for storing nanopore DNA data in an easily accessible way. High performance file format for nanopore reads.
Software semantic segmentation method that automatically adapts to given dataset. Self-configuring method for deep learning-based biomedical image segmentation. Used to analyze provided training cases and automatically configure matching U-Net-based segmentation pipeline.
Software tools for parsing and plotting methylation patterns. Used for plotting methylation data in various ways.
Software tool for working with modified bases from Oxford Nanopore. Used for working with modified bases. Used for quickly converting modBAM to bedMethyl files using best practices, but also manipulating modBAM files and generating summary statistics.
Ultra-fast chromosome-scale phasing algorithm for small and large variants. Ultra-fast program for simultaneously co-phasing SNPs, small indels, large SVs, and (5mC) modifications for Nanopore and PacBio platforms.
Software machine learning framework for large-scale identification of cell states and cellular ecosystems from gene expression data.
Software tool for quick quality assessment of cram and bam files, intended for long read sequencing. Used for for BAM/CRAM quality evaluation, intended for long reads.
Biopac Student Lab system is a flexible, integrated life science teaching solution that includes hardware, software, and curriculum materials. System to conduct basic physiology lab experiments including ECG, EEG, EMG, and EOG. BSL System uses dynamic lessons with students as subjects to increase interest and retention. Students can record data from their own bodies, guided by a detailed lab manual and full color onscreen guide, and analyze the results. Students can then compare data from different experimental conditions with others in their group and with all students in the lab.
Software R package, which is used for calculating sample size and power estimates for RNA-Seq studies.
Cancer research institute located on the Cambridge Biomedical Campus, focused on understanding cancer biology to develop new diagnostics and treatments. It brings together multidisciplinary research groups to translate findings into improved patient outcomes. Part of the University of Cambridge, funded by Cancer Research UK.
Generate publication-ready figures, posters and presentations for any idea. Just describe (or sketch) what you need.