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Core provides infrastructure and analytic support for population-based cancer research at UPMC Hillman Cancer Center. PANDA helps investigators access, manage, link, and analyze population-based cancer datasets to study cancer surveillance, treatment access, and survival in western Pennsylvania and across the United States using datasets such as SEER-Medicare, the Pennsylvania Cancer Registry (PACR), Pennsylvania Health Care Cost Containment Council (PHC4) hospital discharge data, the National Cancer Database (NCDB), and the UPMC Network Cancer Registry, along with area-level and geospatial data relevant to the Hillman catchment area.PANDA provides consultation on study design and data selection, assistance with data management and linkage, analytic dataset creation, population-level and geospatial analyses, and support for manuscripts and grant applications.
Premier Canadian academic medical research center located in Toronto, affiliated with the University of Toronto and Sunnybrook Health Sciences Centre focusing on translating scientific discoveries into clinical practice, with specialties in medical imaging, biology, and clinical trials.
Core offers services including cell sorting,cell analysis, user training for the flow cytometer benchtop analyzers, user training for the widefield and confocal microscopes.
Filmetrics F20 is a versatile, benchtop thin-film measurement system designed to measure the thickness, refractive index, and extinction coefficient of thin films. Using spectral reflectance in less than a second, it measures single or multi-layer stacks.
Advanced, stylus-based surface profiler used for high-precision, 2D and 3D surface topography measurements, including step height, surface roughness, and waviness. System measures roughness in the nanometer range. It provides a step-height repeatability of 5Å. It uses a diamond-tip stylus to physically trace samples, offering sub-nanometer vertical resolution and high repeatability.
A high-speed confocal microscope for 3D imaging of live or fixed biological samples, offering multi-wavelength laser excitation and high-resolution imaging capabilities.
A high-resolution TEM providing imaging, diffraction, and spectroscopic analysis at the atomic scale, suitable for materials science and nanotechnology applications.
An inverted optical microscope designed for high-resolution live-cell imaging, fluorescence microscopy, and advanced multi-channel experiments in cell biology and materials research.
Facility EVG 501 wafer bonder system applies pressure up to 10kN and temperature up to 450C to samples with prepared surfaces (specific chemical surface termination). When the system mechanically brings these surfaces into contact the temperature and pressure sequence activates chemical bonds at the interfaces that fuse the sample surfaces together. A precision wafer bonding system used to join semiconductor wafers using thermal, adhesive, or anodic bonding techniques for device integration.
A thermal processing system used to introduce p-type dopants into semiconductor substrates through controlled diffusion at elevated temperatures.
A high-temperature furnace is used to introduce n-type dopants into semiconductor wafers through controlled diffusion processes.
Fcility AGA Heatpulse 610 is a benchtop rapid thermal annealer (RTA/RTP) that utilizes high power lamps to heat treat thin films and substrates for processes such as contact formation, silicide formation, and dopant diffusion/activation. Temperature control via PID loop has a maximum heating rate of ~50 C/s and maximum temperature of 1000 C. The chamber can also be atmospheric purged with N2, Ar, 4% H2balAr, or O2. A rapid thermal processing system that enables fast heating and cooling cycles for semiconductor wafers, used for dopant activation, oxidation, and material modification.
Facility Oxford ICP-RIE Plaslab 180 utilizes a 3kW RF power supply to generate a remote plasma of Cl2, BCl3, H2, Ar, NF3, O2, SF6, and/or C4F8 gas species that can be further accelerated (300W table bias) toward a substrate resulting in a combination of physical and chemical dry etching for material removal. The turbomolecular pumped system achieves a base pressure < 1E-7 Torr and is equipped with chuck temperature control from -110 to 350 degrees C. Advanced dry etching system combining inductively coupled plasma (ICP) and reactive ion etching (RIE) for highly anisotropic, high-precision material removal in semiconductor and nanofabrication processes.
Facility plasma-enhanced chemical vapor deposition (PECVD) system from AGS utilizes plasma decomposition of silane (SiH4) in in presence of an oxygen or nitrogen source to deposit SiO2 and Si3N4 dielectric thin films. The capacitive coupled plasma reduces the required temperature for deposition to a minimum of ~150degC. A plasma-enhanced chemical vapor deposition system is used to deposit high-quality thin films at reduced temperatures for semiconductor and materials applications.
Facility plasma-enhanced atomic layer deposition (PEALD) system from Arradiance utilizes high-speed pulse valves to sequentially deliver reactants that combine to deposit thin films on the surface of a sample at temperatures up to 300C. Eight precursor positions (4 metalorganic + 4 oxidizer) and three plasma gases (N2, O2, H2) enable a wide range of films and process optimization. Plasma-enhanced atomic layer deposition system used for conformal, atomic-scale thin film growth with excellent uniformity and thickness control.
Facility Angstrom Engineering EvoVac is a thin film deposition system based on evaporation of source material that can deposit a wide range of materials including metals and inorganic compounds. Resistive evaporation results when electrical current heats a boat filled with source material whereas electron beam evaporation utilizes filament emission and magnetic focusing of a high energy electron beam which is swept within a crucible of deposition material. The deposition processes occur in a vacuum to permit long mean free paths from indexed multi-pocket sources at rates and terminal thicknesses controlled using a quartz rate sensor. The substrate can be heated, rotated, and plasma cleaned to control film morphology, uniformity, and adhesion. Vacuum-based deposition system that uses an electron beam to evaporate materials for high-purity thin film coatings with precise thickness control.
Multi-user clean room facility where students and researchers can fabricate films, structures, and devices at micrometer and nanometer scale. Users must enter through the gowning area that contains garments required to protect the cleanroom from particles. The class 10,000 instruction area houses high temperature furnaces, physical vapor deposition systems, wet chemical benches, chemical storage, and electrical test equipment utilized by undergraduate courses. The class 1000 research area houses deposition, etching, thermal treatment, and metrology equipment to support sponsored research and graduate coursework. The class 100 research space hosts the most sensitive lithography process equipment. The utility chase houses support equipment such as water cooling, vacuum pumps, exhaust abatement, and compressed gas delivery systems.
Facility provides infrastructure and technical expertise for maintenance, breeding, and experimental use of Danio rerio. The facility ensures standardized husbandry, health monitoring, and traceability of zebrafish lines in compliance with regulatory and ethical guidelines. Services include colony management, maintenance and distribution of wild-type, mutant, and transgenic lines, and support for experimental workflows. The platform offers technical services such as embryo microinjection (e.g., genome editing using CRISPR/Cas9), phenotypic screening, fin clipping for genotyping, and in vitro fertilization. Training and technical support are available for zebrafish handling, experimental design, and data reproducibility.
Company designs and manufactures specialized laboratory equipment for in vitro research on blood vessels and soft tissues. Based in Vermont, they provide tools for studying vessel pressure, flow, and diameter, primarily used by researchers to understand vascular physiology and disease. Instruments for in-vitro research studies of pressurized, perfused, cannulated blood vessels.
Software pipeline to aid the curation of bird genome assemblies by identifying putative microchromosome scaffolds and moving them to start of the genome assembly FASTA file. Hi-C contact map can then be made using the MicroFinder-ordered assembly file for downstream manual curation. Conserved gene-set mapping and assembly ordering for manual curation of bird microchromosomes. Order FASTA file by microchromosome specific genes.