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The Hereditary Disease Foundation (HDF) aims to cure genetic illness by supporting basic biomedical research. The HDF was started by Dr. Milton Wexler in 1968 when his wife was diagnosed with Huntington''s disease (HD). The Foundation uses a variety of strategies - workshops, grants, fellowships, and targeted research contracts - to solve the mysteries of genetic disease and develop new treatments and cures. Huntington''s disease is a fatal, dominantly inherited, genetic, neurological disorder causing involuntary movements, severe emotional disturbance and progressive cognitive loss over ten to twenty years. Each child of an affected parent has a 50% risk of inheriting HD, usually in the third or fourth decade of life, though children as young as two years and adults in their eighties may also develop symptoms. The Hereditary Disease Foundation uses Huntington''s disease as a model for hereditary disease research because it is triggered by a mutation of one single gene. Progress toward treatment or a cure could be instrumental in finding ways to treat other illnesses with more complex genetics, including Parkinson''s, Alzheimer''s, Lou Gehrig''s disease (ALS), depression, schizophrenia, and cancer. The Hereditary Disease Foundation has given over $50 million to support pioneering research in genetics, gene therapy, molecular and cell biology, cell survival and death, animal models, neurophysiology, neuropharmacology and other areas relevant to understanding inherited diseases. * Milton Wexler Workshop Program: A centerpiece of the Foundation is the interdisciplinary Workshop Program which sponsors Workshops held many times during the year. Milton Wexler began the Program to bring scientists together from different academic disciplines to brainstorm - without prepared lectures or slides - and explore new directions for research. They often share unpublished data. * Funding Opportunities ** The Basic Research Grants Program supports projects that contribute to identifying and understanding the fundamental defects in Huntington''s disease and related disorders. ** The John J. Wasmuth Postdoctoral Fellowships are named in honor of the late John Jacob Wasmuth, an essential member of the Huntington''s Disease Collaborative Research Group. Our hope is that those granted fellowships bearing his name will seek John''s level of imagination, rigor, creativity and spirit. ** The Lieberman Award is presented annually to a worthy scientist, thanks to the generosity of Harry Lieberman, a trustee of the Hereditary Disease Foundation. ** The Milton Wexler Postdoctoral Fellowship Award is named after the founder of the Hereditary Disease Foundation. The Hereditary Disease Foundation restricts this annual award to research highly relevant to curing Huntington''s disease. * Giving to the Hereditary Disease Foundation - Donations are accepted by check, credit card, etc.

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• SciCrunch
• 15 years ago - by Anonymous

The generatation of GPR120-IRES-EGFP knockin mouse Insufficient information. URL doesn't work

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• RRID-Legacy
• 6 years ago - submitted by Yufeng Zhao

Software R package for Gene Ontology enrichment analysis. Offers several methods based on information content and graph structure for measuring semantic similarity among Gene Ontology terms, gene products and gene clusters.

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• RRID
• 1 year ago - by Anonymous

Non-profit repository for the collection, archiving (via cryopreservation) and distribution of relevant mutant strains essential for basic biomedical research. Users may browse by strain, gene, phenotype, or human disease. Its primary objective is to establish and manage a unified repository for maintaining medically relevant mouse mutants and making them available to the scientific community. Therefore, EMMA archives mutant strains and distributes them to requesting researchers. EMMA also hosts courses in cryopreservation, to promote the use and dissemination of frozen embryos and spermatozoa. Dissemination of knowledge is further fostered by a dedicated resource database. Anybody who wants their mutant mouse strains cryopreserved may deposit strains with EMMA. However depositors must be aware that these strains become freely available to other researchers after being deposited.With more than 8400 mutant mouse strains and asmall but increasing number of rat mutant strains available, EMMA is the primary mouse repository in Europe and the third largest non-profit repository worldwide.

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• SciCrunch
• 15 years ago - by Anonymous

original data for The Changed Functional Status of the Brain was Involved in Patients with Post-stroke Aphasia: Coordinate-Based (ALE) Meta-Analysis

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• RRID-Legacy
• 6 years ago - submitted by Yujun Lee

Software multimodal AI-models to estimate Tyrosine Kinase Inhibitors and Immune Checkpoint Inhibitors therapy response across renal cell carcinoma.

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• RRID
• 1 year ago - by Anonymous

Created in 1997, Training Programs in Epidemiology and Public Health Interventions Network (TEPHINET) is a professional network of field epidemiology training programs (FETPs) located in 53 countries around the world. TEPHINET aims to strengthen international public health capacity by training field epidemiologists through an applied apprenticeship program. Trainees of FETPs master a set of core competencies that are vital to the practice of public health, while providing a valuable public health service to their countries and regions.

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• SciCrunch
• 15 years ago - by Anonymous

Web based gene expression database and analysis platform. Used for integrative data mining of genotype and phenotype data, with optimized workflows.

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• RRID-Legacy
• 6 years ago - by Anonymous

Core, within College of Medicine and Health, offers expert support for all aspects of recombinant protein production. Using range of expression systems, produces proteins suitable for diverse downstream applications.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

THIS RESOURCE IS NO LONGER IN SERVICE, documented on April 23, 2014. Description not available.

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• SciCrunch
• 13 years ago - by Anonymous

DataLad data distribution. Super dataset collating DataLad datasets from various sources including OpenNeuro, CRCNS, etc., to provide unified access to over 200TB of neural data.

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• RRID-Legacy
• 6 years ago - submitted by Yaroslav Halchenko

Software package for analysis of RNA expresison data. Used to make pythoneer bioinformatician workflow less colluded with R.

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• RRID
• 1 year ago - by Anonymous

An open source data sharing and visualization platform for neuroimaging data, that uses the OntoNeuroLOG ontology. Shanoir (Sharing NeurOImaging Resources) is an open source neuroinformatics platform designed to share, archive, search and visualize neuroimaging data. It provides a user-friendly secure web access and offers an intuitive workflow to facilitate the collecting and retrieving of neuroimaging data from multiple sources and a wizard to make the completion of metadata easy. Shanoir comes with many features such as anonymization of data, support for multicenter clinical studies on subjects or group of subjects. Shanoir offers an ontology-based data organization (OntoNeuroLOG). Among other things, this facilitates the reuse of data and metadata, the integration of processed data and provides traceability trough an evolutionary approach. Shanoir allows researchers, clinicians, PhD students and engineers to undertake quality research projects with an emphasis on remote collaboration. As a secured J2EE web application, it therefore allows you safely store and archive, with no more requirements than a computer with an internet connection. Furthermore, Shanoir is not only a web application: it is also a complete neuroinformatics platform in which you can easily integrate your existing processing tools or develop your own ones: see ShanoirTk. Shanoir is a project carried out by the VisAGeS Team, based at IRISA (INRIA Rennes - Bretagne Atlantique Research Centre). This software is released under QPL 1.0 license.

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• SciCrunch
• 14 years ago - by Anonymous

Core offers bioinformatics consulting and data analysis services to help researchers analyze and understand large data sets acquired from next generation sequencing and array based technologies.Bioinformatics staff members have extensive experience in bioinformatics, genomics, transcriptomics and translational informatics in plant, animal and microbial systems. Expertise includes big data analysis, statistical analysis, software development and high performance computing.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth

Transmission (TEM), Scanning (SEM), 2D tile scanning SEM and 3DSEM electron microscopy are available in the Core for imaging and analyzing specimens at the ultrastructural level. Possible samples include fresh tissue specimens, cultured cells growing on a substrate, cells in suspension or subcellular fractions (for purity determinations). Sub-cellular localization of antigens within cells by immunogold labeling can be performed, as well as negative staining for visualizing samples such as microparticles and exosomes. Elemental analysis (EDAX) is also available together with SEM.

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• RRID
• 1 year ago - submitted by Matthew Rudy

The Congress of Neurological Surgeons presents surgical videos on a variety of topics: Cerebrovascular, Pain, Pediatric, Peripheral Nerves, Spine, Functional/Epilepsy, and Tumor. You must have QuickTime player installed to view the videos but you can download this from the site. Cerebrovascular * Contralateral Microsurgical Approach to Multiple Aneurysms * Microsurgical Exosure and Clipping of an Ophthalmic Clinoidal Aneurysm Pain * Motor Cortex Stimulation for Chronic Pain * Pain Surgery * Spinal Cord Stimulation for Failed Back Syndrome * Treatment of Chiari I Malformation Pediatric * Occipitocervical Fusion in a Pediatric Patient:Use of a New Device Peripheral Nerves * Brachial Plexus Schwannoma in the Upper Trunk * Mini Open Carpal Tunnel Release * Ulnar Nerve Neurolysis and Subcutaneous/Submuscular Transposition Spine * Bilateral Thoracoscopic Sympathectomy * En Bloc Resection of Primary Cervical Spine Tumors * Endoscopic Thoracic Stabilization * Occipitocervical Fusion in a Pediatric Patient:Use of a New Device * Spinal Cord Stimulation for Failed Back Syndrome * Surgical Management of Spinal Cord Ependymomas * Thoracoscopic Discectomy * Treatment of Chiari I Malformation Functional/Epilepsy * Anteromedial Temporal Resection * STN Deep Brain Stimulation for Parkinson''s Disease Tumor * En Bloc Resection of Primary Cervical Spine Tumors * Insular Tumor Resection * Surgical Management of Spinal Cord Ependymomas * Surgical Resection of Brain Metastasis

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• SciCrunch
• 17 years ago - by Anonymous

Brings together Centers for Disease Control and Prevention, National Institutes of Health, Robert Wood Johnson Foundation, and U.S. Department of Agriculture to accelerate progress in reducing childhood obesity in America, to manage projects and reach common goals, to coordinate funding to make the most of available resources, to share insights and expertise to strengthen research. NCCOR focuses on efforts that have to benefit children, teens, and their families, and communities in which they live.

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• dkNET
• 6 years ago - submitted by Ko-Wei Lin

Provides research data management cyberinfrastructure and is developed and operated as not-for-profit service by the University of Chicago. Researchers can move, share, and discover data across multiple storage system platforms – from supercomputer to lab cluster, tape archive, public cloud or laptop. Globus provides services to design and execute secure, reliable automated task orchestration, across systems and at scale. Remote function execution services enable researchers to execute functions on diverse compute systems.

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• SciCrunch
• 14 years ago - by Anonymous

Repository of peer reviews of antibodies to help scientists find the right tools fast. Researchers from schools including Stanford, Harvard, John Hopkins have contributed reviews of over 1500 antibodies. Most of these reviews contain experimental details that are hard to find in publications and yet crucial for the success of antibody usage. In addition, scientists are enabled to connect through knowledge of expertise, as members are required to use their real names and lab affiliations. BenchWise is currently open to a select list of leading research institutes and is completely free. Scientists waste over 100 hours a year on either bad antibodies or finding out the right antibody usage condition, despite the fact that someone, somewhere likely has already done the same. They want to solve this problem by enabling scientists to share their product usage knowledge. Antibody records that are documented in spreadsheets are also accepted and will be parsed into individual reviews and uploaded to save you time.

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• SciCrunch
• 14 years ago - by Anonymous

Designed to provide supportive environment for interdisciplinary research and education with opportunities for students and faculty members alike with focus on biomolecules study with emphasis on proteins and protein interactions. Provides instrumentation and facilities for characterization of biomolecules and their role in variety of biomedical and environmental processes. Partnerships between Center and Idaho-BRIN/INBRE, UI, ISU, Boise VA Medical Center, College of Idaho, and Northwest Nazarene University. BRC provides seminars, training workshops, and other networking opportunities.

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• SciCrunch
• 6 years ago - submitted by Edyta Vieth