Curator Dashboard

Core provides services for dissection of the immune response both phenotypically, functionally and transcriptionally at the single cell or population level. Technologies like single cell RNAseq (10x Genomics Chromium platform), multispectral fluorescent tissue imaging of FFPE tissues (Vectra 3 Imaging System, Akoya Biosciences), high-performance electrochemiluminescence plexing immunoassays (QuickPlex 120, MSD), and automated multiplexed single-cell and bulk protein analysis system (IsoLight, IsoPlexis) are available to investigators, providing immune cell (and beyond) characterization at the highest resolution. Other services also include project consultation, sample preparation, controlled rate freezing and cryopreservation/storage, as well as a comprehensive range of standardized and customizable immunological assays.

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• 7 months ago - by Anonymous

Metabolomics Core at Robert H. Lurie Comprehensive Cancer Center of Northwestern University provides LCMS based metabolomics services including identification, semi-quantification and quantification of metabolites and integrative genomics services related to metabolism.

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• 7 months ago - by Anonymous

Software R package to calculate the SHapley Additive exPlanations (SHAP) values in polynomial (instead of exponential) time. Supports models produced with xgboost, lightgbm, gbm, ranger, and randomForest packages.

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• 7 months ago - by Anonymous

Software python library for working with Google Sheets allowing users to open spreadsheet by title, key or URL. It also allows to read, write, and format cell ranges and more.

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• 7 months ago - submitted by Monique Surles-Zeigler

Core facility that provides microscopy training, imaging solutions, image processing and analysis services, and consultation. Offers imaging techniques and expertise, including spinning disc confocal microscopy, two-photon confocal microscopy, super resolution microscopy, total internal reflection microscopy, wide field microscopy, fluorescence spectroscopy, photo-manipulation techniques (e.g. FRAP, photoablation, optogenetics, and optical tweezers) and live cell imaging.

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• 7 months ago - by Anonymous

Software novel variational autoencoder framework for inferring integrated latent space representations for single cell transcriptomics data that uses a negative binomial generalized linear model for stronger batch correction, and code compilation for ten times faster training than existing tools. Enables superior analyses of multiple atlases, solving challenging integration tasks across sequencing platforms, development, and species, while simultaneously preserving desired biological signals.

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• 7 months ago - submitted by Edyta Vieth

Department of Medical Illustration’s Medical Sculpture Core advances education and research capabilities in medical sculpture. The space serves as an AU Core Research Lab to provide expertise in medical sculpture, volumetric visualization, and 3D printing. This lab space will offer educational and research opportunities for students to develop medical models such as surgical simulation models and patient education models. The research will improve surgical and medical training and provide insight into materials and technology to improve patient care.

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• 7 months ago - submitted by Amanda Behr

Software tools for fitting Generalized Linear Models (GLMs) with time dependence (a.k.a. filters).

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• 7 months ago - by Anonymous

Spatial Collaborative Services combines expertise and technology from VAIs Genomics Core and Optical Imaging Core to offer investigators a seamless pipeline for spatial imaging. Services include consultation, histology preparation, sequencing and imaging based spatial platforms.

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• 7 months ago - submitted by Edyta Vieth

Provides mixed methods consulting services. Located in the Department of Family Medicine, team advises researchers at all levels in the health and social sciences who are developing proposals for funding, revising a manuscript, completing a research project or requiring Mixed Methods training.

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• 7 months ago - submitted by Edyta Vieth

Core for testing advanced air mobility (AAM), focusing on drones and electric aircraft, especially Beyond-Line-of-Sight (BVLOS) autonomous flight, to accelerate innovation and commercialization in the industry. It serves as a real-world "skyway" for researchers and companies to test new technologies like electric vertical takeoff and landing (eVTOL) aircraft, support Michigan Medicine's air transport, and foster aerospace startups, building on U-M's existing robotics and autonomous vehicle testing facilities.

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• 7 months ago - submitted by Edyta Vieth

Mcity is an interdisciplinary public-private partnership bringing together industry, government, and academia to transform mobility. As part of the U-M Transportation Research Institute, Mcity helps advance safe and efficient transportation and mobility solutions for the benefit of society.Mcity is a makerspace for today’s mobility and transportation innovators. We offer open-source tools, remote or on-site testing, and participation in the Mcity community—learn how to get started.Build and test mobility innovation.

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• 7 months ago - submitted by Edyta Vieth

Core for building and testing mobility innovation is part of the University of Michigan Transportation Research Institute. Helps advance safe and efficient transportation and mobility solutions. Makerspace for mobility and transportation innovators. Offers open-source tools, remote or on-site testing.

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• 7 months ago - submitted by Edyta Vieth

Code to conduct combinatorial barcoding. scRNA-seq-compatible tracer for identifying clonal relationships.

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• 7 months ago - submitted by Edyta Vieth

Software tool that harnesses natural genetic variation to determine the sample identity of each droplet containing a single cell (singlet) and detect droplets containing two cells (doublets). Genetic multiplexing of barcoded single cell RNA-seq.

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• 7 months ago - submitted by Edyta Vieth

Software Python package for single-cell chromosome contact data analysis. It includes the identification of cell types (clusters), loop calling in cell types, and domain and compartment calling in single cells. Facilitates visualization and comparison of single-cell 3D genomes.

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• 7 months ago - submitted by Edyta Vieth

EM Core Facility offers instrumentation and training for range of Electron Microscopy applications. Instrumentation includes Thermofisher Tundra cryo-TEM, Tecnai T12 TEM, Magellan 400 SEM, JEOL JEM-2200FS, Vitrobot Mark IV, (cryo)microtomes, and other auxiliary equipment.

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• 7 months ago - by Anonymous

Particle analysis system that uses Nanoparticle Tracking Analysis (NTA) to measure the size distribution, concentration, and aggregation of nanoparticles (10-2000 nm) in liquid, crucial for research in exosomes, drug delivery, protein aggregation, and colloidal systems. It visualizes individual particles' Brownian motion with lasers and a camera, calculating hydrodynamic diameter and concentration, and includes fluorescence detection for specific labeled particles.

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• 7 months ago - by Anonymous

Upright light microscope used in research, education, and routine lab work for detailed sample observation, documentation, and analysis in fields like pathology, histology, cytology, and materials science, supporting various techniques like brightfield, fluorescence, and polarization microscopy for capturing sharp digital images.

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• 7 months ago - by Anonymous

Software application for topic modeling with latent Dirichlet allocation.

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• 7 months ago - submitted by Seppe De Winter