Curator Dashboard

Core is part of the University of Manchester Faculty of Science and Engineering. Facility offers support and services in chemistry, biology and materials. Mass spectrometers including Orbitraps, Ion Mobility, MALDI, DESI, hyphenated LC-MS and GC-MS apparatuses. Other instruments are HPLC systems, UHPLC systems and GC systems.

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• 3 years ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. Study of genetic and life-style risk factors associated with common diseases based on analysis of European twins. The population cohorts used in the Genomeutwin study consist of Danish, Finnish, Italian, Dutch, English, Australian and Swedish twins and the MORGAM population cohort. This project will apply and develop new molecular and statistical strategies to analyze unique European twin and other population cohorts to define and characterize the genetic, environmental and life-style components in the background of health problems like obesity, migraine, coronary heart disease and stroke, representing major health care problems worldwide. The participating 8 twin cohorts form a collection of over 0.6 million pairs of twins. Tens of thousands of DNA samples with informed consents for genetic studies of common diseases have already been stored from these population-based twin cohorts. Studies targeted to cardiovascular traits are now being undertaken in MORGAM, a prospective case-cohort study. MORGAM cohorts include approximately 6000 individuals, drawn from population-based cohorts consisting of more than 80 000 participants who have donated DNA samples.

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• SciCrunch
• 15 years ago - by Anonymous

Consortium for the cell census in the brain. Integrated network of data generating centers, data archives, and data standards developers, with the goal of systematic multimodal brain cell type profiling and characterization. Emphasis of the BICCN is on the whole mouse brain with demonstration of prototype feasibility for human and nonhuman primate brains.

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• 9 years ago - submitted by Anita Bandrowski

Core includes range of surface analysis techniques and supportive instruments across three research institutes: Henry Royce Institute, Photon Science Institute, and National Graphene Institute.

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• 3 years ago - submitted by John Warren

ORNIS is a database of bird specimens as well as a portal to connect the academic and museum communities involved with studying birds. This project expands on existing infrastructure developed for distributed mammal (MaNIS), amphibian and reptile (HerpNet), and fish (FishNet) databases. Over 5 million bird specimens are housed in North American collections, documenting the composition, distribution, ecology, and systematics of the world's estimated 10,000-16,000 bird species. Millions of additional observational records are held in diverse data sets. ORNIS addresses the urgent call for increased access to these data in an open and collaborative manner, and involves development of a suite of online software tools for data analysis and error-checking. This project expands on existing infrastructure developed for distributed mammal (MaNIS), amphibian and reptile (HerpNet), and fish (FishNet) databases. Improved access to avian data sets will allow predictive uses to reveal patterns and processes of evolutionary and ecological phenomena that have not been apparent heretofore. Along with similar infrastructures for other vertebrate groups, it also will enable detailed and synthetic knowledge of the earth's biodiversity for tracking climate change, emerging diseases (e.g., West Nile Virus), and other conservation challenges for species in the 21st century.

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• SciCrunch
• 17 years ago - by Anonymous

Data services that provides a platform for comprehensive and reproducible management and sharing of neuroscience data. Building on well established versioning technology, GIN offers the power of a web based repository management service combined with a distributed file storage.

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• SciCrunch
• 9 years ago - submitted by Thomas Wachtler

Software package provides several scale functions to break down ‘gg’ plot into pieces and align them together with gap plot or without (wrap plot or cut plot) ignoring subplots. Package was first designed to set breakpoints for truncating plot to shrink outlier long branch of phylogenetic tree. Set Axis Break for ggplot2.

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• RRID
• 3 years ago - by Anonymous

National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.

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• SciCrunch
• 17 years ago - by Anonymous

Database of positive selection based on a rigorous branch-site specific likelihood test. Positive selection is detected using CODEML on all branches of animal gene trees.

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• SciCrunch
• 17 years ago - by Anonymous

Software Snakemake workflow for scoring and comparing multiple bacterial genome assemblies from Illumina and Nanopore to reference genomes.

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• RRID
• 3 years ago - by Anonymous

Database for functional enzyme and ligand-related information maintained as part of the German ELIXIR Node. Provides advanced query systems, evaluation tools, and various visualization options for the detailed assessment of enzyme properties. Enzyme data in BRENDA are classified according to the Enzyme Commission (EC) nomenclature of IUBMB.

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• SciCrunch
• 16 years ago - by Anonymous

Core provides bioinformatics specialists available to assist researchers with processing, exploring, and understanding genomics data.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Database of proteins undergoing liquid–liquid phase separation in vitro. Contains LLPS related proteins together with the corresponding phase separation conditions validated by experiments.

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• 3 years ago - by Anonymous

Produce resources to unravel the interface between insulin action, insulin resistance and the genetics of type 2 diabetes including an annotated public database, standardized protocols for gene expression and proteomic analysis, and ultimately diabetes-specific and insulin action-specific DNA chips for investigators in the field. The project aims to identify the sets of the genes involved in insulin action and the predisposition to type 2 diabetes, as well as the secondary changes in gene expression that occur in response to the metabolic abnormalities present in diabetes. There are five major and one pilot project involving human and rodent tissues that are designed to: * Create a database of the genes expressed in insulin-responsive tissues, as well as accessible tissues, that are regulated by insulin, insulin resistance and diabetes. * Assess levels and patterns of gene expression in each tissue before and after insulin stimulation in normal and genetically-modified rodents; normal, insulin resistant and diabetic humans, and in cultured and freshly isolated cell models. * Correlate the level and patterns of expression at the mRNA and/or protein level with the genetic and metabolic phenotype of the animal or cell. * Generate genomic sequence from a panel of humans with type 2 diabetes focusing on the genes most highly regulated by insulin and diabetes to determine the range of sequence and expression variation in these genes and the proteins they encode, which might affect the risk of diabetes or insulin resistance. The DGAP project will define: * the normal anatomy of gene expression, i.e. basal levels of expression and response to insulin. * the morbid anatomy of gene expression, i.e., the impact of diabetes on expression patterns and the insulin response. * the extent to which genetic variability might contribute to the alterations in expression or to diabetes itself.

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• dkNET
• 14 years ago - by Anonymous

Analysis software that identifies antibiotic resistance genes by running local assemblies. It can also be used for MLST calling.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Core offers education, analysis, and computational services in the area of bioinformatics and computational biology. Offers initial consultations to help with experimental design and power analysis of 'omics data for grant submissions and bioinformatics needs for current projects.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

A XML-based description language that provides a common data format for defining and exchanging descriptions of neuronal cell and network models. It facilitates the exchange of complex neural models, allows for greater transparency and accessibility of models, enhances interoperability between simulators and other tools, and supports the development of new software and databases. Exchange of network models will aid the investigation of structure-function relationships in neuroscience including theoretical studies relating connectivity patterns to normal and neurodegenerative network states. NeuroML is a free and open community effort developed with input from many contributors. They will need your help as the standards and tools continue to evolve.

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• SciCrunch
• 14 years ago - by Anonymous

Software package for comparative analysis of the sequences of a sample of bacterial genomes in order to reconstruct the recombination events that have taken place in their ancestry.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

NIH funded collaboration between researchers and librarians to build behavioral project oriented data repository containing decades of knowledge from educational and developmental sciences on individuals across the full range of abilities.

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• 2 years ago - by Anonymous

Request for Applications to fund the best ideas in the field of hyperphagia research. Institutions of Higher Education, Nonprofit organizations, For-profit companies are eligible.

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• SciCrunch
• 13 years ago - by Anonymous