We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Core provides instruction and access to scanning electron microscopes, transmission electron microscopes, laser capture microscopes, and confocal laser scanning microscopes. CAM staff members help with microscopes and microscopy analysis.
Repository of biological models created using CellML, a free, open-source, eXtensible markup language based standard for defining mathematical models of cellular function. Models may be browsed by category, which include: Calcium Dynamics, Cardiovascular Circulation, Cell Cycle, Cell Migration, Circadian Rhythms, Electrophysiology, Endocrine, Excitation-Contraction Coupling, Gene Regulation, Hepatology, Immunology, Ion Transport, Mechanical Constitutive Laws, Metabolism, Myofilament Mechanics, Neurobiology, pH Regulation, PKPD, Signal Transduction, Synthetic Biology. The community can contribute their models to this resource.
The Institute of Biological Sciences (INSB) is a CNRS institute that develops and coordinates research in biological sciences with the overall aim to better understand life in all its complexity, starting at the level of atoms and biomolecules, extending to cells and through to organisms and populations. Scientific fields: structural biology, bioinformatics, pharmacology, neuroscience, cognitive science, immunology, genetics, cell biology, microbiology, physiology, plant biology, systems biology, biodiversity...
Software tool to detect linear enrichment of somatic mutations in user-defined regions of interest.
Species 2000 is a federation of database organizations working closely with users, taxonomists and sponsoring agencies. The goal of the Species 2000 project is to create a validated checklist of all the world''s species (plants, animals, fungi and microbes). This is being achieved by bringing together an array of global species databases covering each of the major groups of organisms. Each database covers all known species in the group, using a consistent taxonomic system. The participating databases are widely distributed throughout the world and currently number 52. The existing global species databases presently account for some 60% of the total known species, so substantial investment in new databases will be needed for full coverage of all taxa to be achieved.
The Ministry of Foreign Affairs and is the ministry in the government of France that handles France's foreign relations.
Offers investigators clinical space, equipment, skilled nursing and nutrition services, project management and study coordinator support, resources for conducting community engagement research, as well as one-on-one consultation with Clinical/Translational Research Navigators.
Extensible, scriptable, pythonic software tool for visualization and analysis in structural neuroimaging research on many spatial scales. Employing the Connectome File Format, diverse data such as networks, surfaces, volumes, tracks and metadata are handled and integrated. The field of Connectomics research benefits from recent advances in structural neuroimaging technologies on all spatial scales. The need for software tools to visualize and analyze the emerging data is urgent. The ConnectomeViewer application was developed to meet the needs of basic and clinical neuroscientists, as well as complex network scientists, providing an integrative, extensible platform to visualize and analyze Connectomics data. With the Connectome File Format, interlinking different datatypes such as hierarchical networks, surface data, volumetric data is easy and might provide new ways of analyzing and interacting with data. Furthermore, ConnectomeViewer readily integrates with: * ConnectomeWiki: a semantic knowledge base representing connectomics data at a mesoscale level across various species, allowing easy access to relevant literature and databases. * ConnectomeDatabase: a repository to store and disseminate Connectome files.
A major biomedical research institute located in the northeastern corner of Berlin, Germany, with a mission of translating discoveries from molecular research into applications to improve the prevention, diagnosis, and treatment of major human diseases. The work of the MDC''s 57 research groups centers around three classes of disease which have an enormous impact on society: * Cardiovascular and metabolic diseases * Cancer * Nervous system disorders
Core Facility provides functional genomics, highthroughput screening (HTS), and high-content screening (HCS) services toward the discovery of novel cancer targets and elucidation of complex, aberrant cellular pathways. Offers assistance and training in range of cloning, customized library design, lentivirus production, assay development, screening, and image analysis considerations to assist researchers in harnessing these powerful target identification tools and drug screening methodologies. Offers CRISPR-mediated transcriptional activation/interference (CRISPRa/CRISPRi) technologies combined with lentivirus delivery systems, customized stable isogenic cell line generation (knockout, HDR-directed knock-in, knockdown, base editing, and prime editing) toward the generation of unique cancer cell line models.
THIS RESOURCE IS NO LONGER IN SERVICE, documented on January 29, 2013. Supplemental data for the paper Changes in mitochondrial function resulting from synaptic activity in the rat hippocampal slice, by Vytautas P. Bindokas, Chong C. Lee, William F. Colmers, and Richard J. Miller that appears in the Journal of Neuroscience June 15, 1998. You can view digital movies of changes in fluorescence intensity by clicking on the title of interest.
The largest agricultural research institute in Japan for basic life sciences focusing on understanding the biological phenomena of agriculturally important plants, insects, microbes and animals to create innovative technologies, and eventually contribute to the solution of global issues such as food shortage due to rapid population growth and environmental problems due to climate change. Research activities are pursued in a 5-year cycle to intensify all efforts towards a common goal and to forge the way for new breakthroughs with direct impact to agricultural productivity.
Represents central facility and does not operate for profit, engaging in academic research collaborations and service provision on collaborative basis. Provides infrastructure for all kinds of sequencing, gene mapping and whole genome association studies in complex diseases as well as the validation of copy number variations.
It is a specialized research center supported by the Protein Structure Initiative (PSI) of the National Institute of General Medical Sciences (NIGMS), one of the National Institutes of Health (NIH). PSI is a federal, university, and industry effort aimed at dramatically reducing the costs and lessening the time it takes to determine a three-dimensional protein structure. The long-range goal of PSI is to solve 10,000 protein structures in 10 years and to make the three-dimensional atomic-level structures of most proteins easily obtainable from knowledge of their corresponding DNA sequences. CESG is located within the Department of Biochemistry at the University of Wisconsin-Madison (Madison, WI) and the Department of Biochemistry at the Medical College of Wisconsin (Milwaukee, WI). CESG develops new methods and technologies to address unique eukaryotic bottlenecks and disseminates its methodologies and experimental results to the scientific community worldwide through: :- Cell-Free Protein Production Workshops :- Plasmids at PSI Materials Repository :- Posters Presented at Scientific Meetings :- Publications in PubMed / PubMed Central :- Sesame (LIMS) Available for Researchers :- Solved Structures in the Protein Data Bank :- Technology Dissemination Reports They have welcomed requests by researchers to solve eukaryotic protein structures, particularly medically relevant proteins, through our Online Structure Request System for Researchers. They have solved many community-nominated targets and deposited information about these targets in public databases and published on our investigations and findings. Sponsors: CESG is supported by NIH / NIGMS Protein Structure Initiative grant numbers U54 GM074901 and P50 GM064598.
StemCore Laboratories is a high-throughput genomics facility within the Ottawa Hospital Research Institute (OHRI). StemCore Laboratories is developing a world-class infrastructure for genomics, bioinformatics, and proteomics, and is capable of facilitating large-scale scientific research and biotechnology projects. Stemcore Laboratories seeks out projects that are challenging, cutting-edge, extend the boundaries of biological knowledge, and will positively impact the state of human health. Funded: Genome Canada, The Ontario Genomics Institute, The Canadian Foundation for Innovation, The Government of Ontario, The Stem Cell Network, Stantive Solutions
Core facility that provides microscopy training, imaging solutions, image processing and analysis services, and consultation. Offers imaging techniques and expertise, including spinning disc confocal microscopy, two-photon confocal microscopy, super resolution microscopy, total internal reflection microscopy, wide field microscopy, fluorescence spectroscopy, photo-manipulation techniques (e.g. FRAP, photoablation, optogenetics, and optical tweezers) and live cell imaging.
AMSER is a portal of educational resources and services built specifically for use by those in Community and Technical Colleges but free for anyone to use. AMSER provides links to resources for faculty, staff, librarians, students and others for use in both educational settings or in their pursuit of life long learning. Sponsors: AMSER is funded by the National Science Foundation (NSF) as part of the National Science Digital Library, and is being created by a team of project partners led by Internet Scout.
Hospital known officially as the Sir Mortimer B. Davis Jewish General Hospital since 1978, is an acute-care teaching hospital in Montreal, Quebec, Canada. The hospital is affiliated with McGill University
This dataset includes human brain stimulated-echo (STE) diffusion MRI (dMRI) images acquired at the long diffusion time of 1 second from 10 healthy volunteers and an ex vivo brain hemisphere, as described by Aganj et al (MRM 2026). Also included are MPRAGE T1 images for all scans and standard dMRI images for the 10 in vivo scans. All images have been anonymized, and the T1 images have been de-faced.
Provides support for the Apache community of open-source software projects. The Apache projects are characterized by a collaborative, consensus based development process, open and pragmatic software license, and a desire to create high quality software that leads the way in its field.