Curator Dashboard

database of the research

• Resource
• RRID
• 11 months ago - by Anonymous

The annual Cosyne meeting provides an inclusive forum for the exchange of experimental and theoretical/computational approaches to problems in systems neuroscience. The first Cosyne meeting, held in 2004 at Cold Spring Harbor Laboratory, drew over 350 participants. Since 2005, the meeting has been held in Salt Lake City, Utah. It has attracted a growing number of participants, from nearly 400 in 2005 to over 500 in 2010. To encourage interdisciplinary interactions, the main meeting is arranged in a single track. A set of invited talks are selected by the Executive Committee, and additional talks and posters are selected by the Program Committee, based on submitted abstracts. Cosyne topics include but are not limited to: neural coding, natural scene statistics, dendritic computation, neural basis of persistent activity, nonlinear receptive field mapping, representations of time and sequence, reward systems, decision-making, synaptic plasticity, map formation and plasticity, population coding, attention, computation with spiking networks. Sponsor. Thanks to the generosity of The Gatsby Charitable Foundation, of Qualcomm Incorporated and of Brain Corporation, up to 40 travel grants will be available to support student and postdoc participation in the main Cosyne meeting.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

The NIH Clinical Center is the nation's largest hospital devoted entirely to clinical research. Clinician-investigators translate scientific observations and laboratory discoveries into new approaches to diagnosing, treating, and preventing disease. The Clinical Center was recognized with the 2011 Lasker~Bloomberg Public Service Award for serving as a model research hospital—providing innovative therapy and high-quality patient care, treating rare and severe diseases, and producing outstanding clinician-scientists whose collective work has set a standard of excellence in biomedical research. About 1,500 clinical research studies are in progress at the Clinical Center. Half are studies of the natural pathogenesis of disease, especially rare diseases, which often are not studied anywhere else. What researchers learn by studying rare diseases adds to the basic understanding of common diseases. Most other studies are clinical trials, the first tests of new drugs and therapies in people. The clinical trials at the Clinical Center are predominantly Phase I and Phase II—first-in-human to test safety and efficacy. Clinical and laboratory research is conducted shoulder-to-shoulder, and this tandem approach drives all aspects of the Clinical Center's operations. More than 400,000 research volunteers have participated in clinical research studies at the Clinical Center since the hospital opened in 1953. Each year, the center sees 10,000 new research participants, of which there are two types: patient volunteers and healthy volunteers. Patient volunteers are people with specific diseases or conditions who help medical investigators learn more about their condition or test new medications, procedures, or treatments. A healthy volunteer is a person with no known significant health problems who plays a vital role in research to test a new drug, device, or intervention. At the Clinical Center, clinical research participants are active partners in medical discovery, a partnership that has resulted in a long list of medical milestones, including the first cure of a solid tumor with chemotherapy, gene therapy, use of AZT to treat AIDS, and successful replacement of a mitral valve.

• Resource
• SciCrunch
• 18 years ago - submitted by Andrea Stagg

Core provides services for dissection of the immune response both phenotypically, functionally and transcriptionally at the single cell or population level. Technologies like single cell RNAseq (10x Genomics Chromium platform), multispectral fluorescent tissue imaging of FFPE tissues (Vectra 3 Imaging System, Akoya Biosciences), high-performance electrochemiluminescence plexing immunoassays (QuickPlex 120, MSD), and automated multiplexed single-cell and bulk protein analysis system (IsoLight, IsoPlexis) are available to investigators, providing immune cell (and beyond) characterization at the highest resolution. Other services also include project consultation, sample preparation, controlled rate freezing and cryopreservation/storage, as well as a comprehensive range of standardized and customizable immunological assays.

• Resource
• RRID
• 10 months ago - by Anonymous

Mission The Foundation for Informed Medical Decision Making is a non-profit organization dedicated to assuring that people understand their choices and have the information they need to make sound decisions affecting their health and well being. To accomplish our mission: We promote understanding and adoption of informed medical decision-making. We organize and frame medical evidence in an unbiased manner to help people evaluate their options, particularly in instances where differences in individual preferences and perspectives are likely to affect personal choice. We sponsor research to expand knowledge of how to improve decision quality in health care. Medical Evidence The science of medical care is advancing at a rate that makes the delivery of quality patient-focused care an enormous challenge. New information about disease biology and genetics, rapid development of new tests and treatments, and the shift in disease from largely acute to largely chronic are all important contributing factors. Patient Perspective Medical research on practice variation indicates that patient perspectives are often less important in treatment decisions than factors having little to do with patients or their illnesses, such as geography, economics or supplier-induced demands. The Foundation brings the patient perspective into focus by interviewing real patients who can talk about the choices they made and why. Without the perspective of the patient, we cannot achieve a quality medical decision. Informed Medical Decisions The Foundation believes that it is the convergence of the two concepts: medical evidence and patient perspectives that create a truly informed decision in medical care. Funding The Foundation has worked in a unique partnership with Health Dialog since 1997. Health Dialog delivers patient support services to employers and health plans that are committed to providing excellence to their members or employees. As of July 2006, Health Dialog served seventeen million people through its contracts with healthcare insurers and corporations. Access to the Foundation''s decision support materials is a key benefit that Health Dialog''s clients receive. Health Dialog produces the Foundation''s new programs and distributes decision support materials and services to patients. A portion of Health Dialog''s revenue goes to the Foundation in the form of royalties to support the development of new decision support materials and research on how best to support patient decisions. The Foundation does not accept funding from any source that has a financial interest in any particular approach to medical testing or treatment. Foundation employees and clinical content experts do not accept support from companies that commercially market any kind of treatment or device that might be relevant to a program.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Federal research facility in Livermore, California, United States, founded by the University of California, Berkeley in 1952.

• Resource
• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Core has personnel with expertise in all aspects of Mass Spectrometry Imaging. Provides spatial mapping of biomolecules from tissue sections using Matrix Assisted Laser Desorption/Ionization (MALDI) and Secondary Ion Mass Spectrometry (SIMS).

• Resource
• RRID
• 10 months ago - by Anonymous

This site provides several tools for selecting zinc finger protein (ZFP) target sites and for designing the proteins that will target them. These ZFPs can be fused with effector domains that confer transcriptional activation or repression activity as well as catalytic functions.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

In the Tata Institute of Fundamental Research we do basic research in physics, chemistry, biology, mathematics and computer science. We have campuses in Mumbai, Pune and Bangalore and research facilities in various other places in India. We have master''s and doctoral programs in our fields of work. TIFR is an autonomous Institute under the umbrella of the Department of Atomic Energy of the Government of India.

• Organization
• SciCrunch
• 17 years ago - submitted by Andrea Stagg

Data resource for clinical transcriptomes with cancer treatment response, and meanwhile supports various data analysis functions, providing insights into the molecular determinants of drug resistance. CTR-DB 2.0 is updated cancer clinical transcriptome resource, expanding primary drug resistance and newly adding acquired resistance datasets and enhancing the discovery and validation of predictive biomarkers.

• Resource
• RRID
• 9 months ago - by Anonymous

A network of protein-protein, protein-DNA and modulatory interactions in human B cells. The network contains known interactions (reported in public databases) and predicted interactions by a Bayesian evidence integration framework which integrates a variety of generic and context specific experimental clues about protein-protein and protein-DNA interactions with inferences from different reverse engineering algorithms, such as GeneWays and ARACNE. Modulatory interactions are predicted by the MINDY, an algorithm for the prediction of modulators of transcriptional interactions (please refer to the publication section for more information). The BCI can be downloaded as one tab delimited file containing the complete network (BCI.txt) with each type of interaction explicitly defined.

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Scientific agency of the United States government. The scientists of the USGS study the landscape of the United States, its natural resources, and the natural hazards that threaten it. The organization's work spans the disciplines of biology, geography, geology, and hydrology.

• Resource
• SciCrunch
• 17 years ago - submitted by Andrea Stagg

Mayo Clinic's Biomedical Imaging Resource Core in Rochester, Minnesota, focuses on supporting and advancing research in biomedical imaging and visualization sciences. Provides guidance on protocol design, routine image analysis, and custom software and hardware solutions. Also, media and model production resources are available to investigators for the creation of high-quality visualizations and physical models of research data.Core provides services to all Mayo Clinic faculty and staff engaged in research. Also, services may be available on a limited basis to investigators and research collaborators outside Mayo Clinic. Before scheduling, contact the core to design optimal settings for the specified imaging task.

• Resource
• SciCrunch
• 9 months ago - submitted by Edyta Vieth

Non-profit organization dedicated to solving the author/contributor name ambiguity problem in scholarly communications by creating a central registry of unique identifiers for individual researchers and an open and transparent linking mechanism between ORCID and other current author ID schemes. These identifiers, and the relationships among them, can be linked to the researcher''s output to enhance the scientific discovery process and to improve the efficiency of research funding and collaboration within the research community. The ideal solution is to establish a registry that is adopted and embraced as the de facto standard by the whole of the community. A resolution to the systemic name ambiguity problem, by means of assigning unique identifiers linkable to an individual''s research output, will enhance the scientific discovery process and improve the efficiency of funding and collaboration. The organization brings together the leaders of the most influential universities, funding organizations, societies, publishers and corporations from around the globe and is managed by a fourteen member Board of Directors. A disambiguated set of authors will allow new services and benefits to be built for the research community by all stakeholders in scholarly communication: from commercial actors to non-profit organizations, from governments to universities.

• Resource
• SciCrunch
• 16 years ago - by Anonymous

The California Institute for Regenerative Medicine is accelerating the development of new therapies for chronic disease and injury by funding stem cell research programs throughout California. T he mission of CIRM is to support and advance stem cell research and regenerative medicine under the highest ethical and medical standards for the discovery and development of cures, therapies, diagnostics and research technologies to relieve human suffering from chronic disease and injury. CIRM was established in 2004 after Californians passed Proposition 71, the California Stem Cell Research and Cures Initiative. The statewide ballot measure, which provided 3 billion in funding for stem cell research at California universities and research institutions, called for the establishment of a new state agency to make grants and provide loans for stem cell research, research facilities and other vital research opportunities. CIRM funds stem cell research at for-profit and not-for-profit institutions throughout California. Grants are awarded as part of Requests for Applications (RFAs). Applications for these RFAs are reviewed by a panel of experts, which makes recommendations to the Governing Board. The board then votes on grants to fund for each RFA. Keywords: Regenerative, Medicine, Development, Therapy, Chronic, Disease, Ilness, Stem cell, Research, Meidcal, Discovery, Cure, Therapy, Diagnostic, Technology, Human, Grant, Funding,

• Resource
• SciCrunch
• 17 years ago - by Anonymous

Specialized research and graduate training university in Quebec, Canada, founded in 1969. It is the only institution in Quebec dedicated exclusively to graduate studies (master's and doctoral level) and applied research in four key strategic sectors: water/environment, energy/materials/telecommunications, urbanization/culture, and health/biotechnology.

• Resource
• RRID
• 9 months ago - submitted by Edyta Vieth

This software package provides the implementation of distance weighted discrimination (DWD) using an interior point method for the solution of second order cone programming problems.

• Resource
• SciCrunch
• 13 years ago - by Anonymous

Department of the Government of Canada responsible for the country's federal health policy. It is overseen by the minister of health as part of the minister's health portfolio.

• Resource
• SciCrunch
• 13 years ago - submitted by Andrea Stagg

Open community portal for multi-species mammalian adipose biology. Aggregates data for adipose tissues and cell types, genes active within them, and their relationship to human phenotypes. Plans to offer reproducible analysis pipelines, wet lab and computational protocols, datasets, analyses, and visualizations for epigenomic, transcriptomic, proteomic, metabolomic, and imaging data. Designed to aggregate and harmonize multi-species (human and mouse) transcriptomic, genetic, and epigenomic data. Enables to explore adipose biology, cell-type-specific gene expression, and metabolic disease mechanisms through interactive tools like Single Cell Browsers.

• Resource
• dkNET
• 9 months ago - submitted by Maryann Martone

THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. Service that determines the Suspected Overlap Among OBO Foundry Candidate Ontologies.

• Resource
• SciCrunch
• 15 years ago - by Anonymous