Curator Dashboard

Core offers microscopy services. Provides three offline analysis systems with Intel Xeon-based processors. Two of these are custom-built Origin computers and the third is a Dell Precision computer. All analysis workstations have the most recent versions of the Fiji build of Image J and RStudio.

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• 6 months ago - by Anonymous

cGMP facility responsible for the bulk product manufacture, purification, and characterization of clinical-grade materials. Offers vialing of sterile investigational products such as peptides, proteins, carbohydrates, and adjuvants. Service also conducts lot release tests which are required for products release for preclinical and investigational use either in-house or with validated contract vendors.

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• SciCrunch
• 6 months ago - submitted by Edyta Vieth

Core provides services in confocal microscopy (CLSM, including FRET, ion imaging, and colocalization), scanning electron microscopy (SEM, including ESEM for wet samples), SEM prep instrumentation (critical point dryer and sputter coater), epifluorescence microscopy and polarizing microscopy.

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• SciCrunch
• 6 months ago - submitted by Edyta Vieth

Core provides tissue processing, histology and staining services. Services include embedding, sectioning, histochemical staining of mounted slides, immunohistochemical (IHC) staining for paraffin embedded and frozen tissues, immunocytochemical (ICC) staining for cultured cells (as tissue sections or cytospin slides), evaluation of new antibodies for IHC staining, enzyme histochemistry and special staining.Provides defined analyses including RNA / DNA preparation, reverse transcription and cDNA synthesis from total RNA, construction, staining and analysis of tissue microarrays, and construction and analysis of reverse proteomics array from user-defined biospecimens.Core is flexible to accommodate the development of new techniques and expanding its services based on the research requirements of SCC members and other investigators.

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• SciCrunch
• 6 months ago - submitted by Edyta Vieth

Software R package read flat files (csv, tsv, fwf) into R. Used to read rectangular data like 'csv', 'tsv', and 'fwf'. Designed to flexibly parse many types of data found in the wild, while still cleanly failing when data unexpectedly changes.

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• 6 months ago - by Anonymous

Contract research organization based in San Leandro, California, that specializes in molecular pathology, genomics, and tissue analysis. Services for drug discovery, biomarker development, and personalized medicine. Provides histopathology and genomic services to the pharmaceutical and biotechnology industries.

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• 6 months ago - by Anonymous

Specialty contract research laboratory and biotechnology company that provides stem cell testing and in vitro toxicity screening, particularly for the blood-forming (hematopoietic) system. Provides high-throughput hematotoxicity screening and testing with its proprietary HALO®-Tox HT Platform. Provides the expertise to help in predicting toxicity, risk and safety of a drug or other agent.

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• 6 months ago - by Anonymous

Laboratory instrument designed to analyze and quantify ELISpot, FluoroSpot, and FociSpot assays in 96-well plates. Used by immunologists and vaccine researchers to study individual immune cells and detect secretions like antibodies and cytokines. Capable of analyzing up to four analytes simultaneously.

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• 6 months ago - by Anonymous

Research-grade upright compound microscope used to visualize fluorescently labeled cells, tissues, and biological markers. Equipped with interchangeable filter cubes (e.g., DAPI, FITC, TRITC), it excites specific fluorophores to study gene expression, protein localization, and cellular dynamics. Beyond fluorescence, it supports brightfield, phase contrast, and Differential Interference Contrast (DIC) for examining unlabeled or transparent specimens. Often fitted with trinocular head and high-resolution digital camera to capture publication quality micrographs and record time-lapse imagery.

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• 6 months ago - by Anonymous

Specialized service at Charité – Universitätsmedizin Berlin that provides researchers with fresh, high-quality primary human biospecimens. By bypassing standard supply chains, it connects operating and clinical wards directly to research laboratories, supporting human-based methods to reduce reliance on animal experimentation. Operates as a central contact point, taking care of the logistics from project initiation to sample transfer. It coordinates with surgical clinics, pathology departments, and tissue repositories. Alongside the living biospecimens, the pipeline helps safely transfer relevant, pseudonymized patient data to research groups.

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• SciCrunch
• 6 months ago - by Anonymous

Software application as discrete event simulation model built in the R programming language which simulates individual women through different risk-stratified breast screening programmes. Used to evaluate the costs, outcomes, and cost-effectiveness of different breast cancer screening strategies, particularly risk-stratified approaches in the UK. It helps policymakers determine the best screening intervals for women based on risk rather than just age.

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• 6 months ago - by Anonymous

Software tool for rapidly determining the low-resolution three-dimensional shape of biological macromolecules in solution using Small-Angle X-ray Scattering (SAXS) data. Used for rapid ab-initio shape determination in small-angle scattering.

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• 6 months ago - by Anonymous

Database of glycans 3D structural data and information that can be downloaded or used with Re-Glyco to rebuild glycoproteins from the RCSB PDB or EMBL-EBI AlphaFold repositories. Glycan structure database and toolbox designed to restore glycoproteins to their native and functional form.

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• 6 months ago - by Anonymous

Software program designed for refining atomic models of multidomain proteins or complexes using Small-Angle X-ray Scattering (SAXS) data. It is specifically used in structural biology to help determine the 3D structure of complex molecules in solution.

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• 6 months ago - by Anonymous

Software command-line tool designed for hard-filtering variant callsets (VCF files) by applying user-defined criteria to annotate, rather than remove, low-quality variants. It marks fails in the FILTER field (e.g., using JEXL expressions to filter by DP, QD, or FS), making it essential for filtering small datasets, non-model organisms, or whenever Variant Quality Score Recalibration (VQSR) is not feasible

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• 6 months ago - by Anonymous

Software tool for identifying single nucleotide polymorphisms (SNPs) and insertion/deletion (indels) variants, offering high accuracy via local de-novo assembly of reads. It works by identifying "active regions" with potential variation, reassembling those reads, and calculating genotype likelihoods, making it superior for complex variant detection.

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• 6 months ago - by Anonymous

Command-line utility provided by the UCSC Genome Browser to convert text-based bedGraph files into indexed binary bigWig files. It is specifically used in bioinformatics to transform dense, continuous genome coverage data into a format that enables fast visualization and remote viewing in genome browsers like IGV or the UCSC Genome Browser.

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• 6 months ago - by Anonymous

The open‑field test system for neurobehavioural analysis is designed to observe and investigate neuropsychiatric changes in experimental animals, as well as their diverse behaviours upon entry into an open environment. Animals typically exhibit fear of novel open spaces, leading them to move predominantly in the peripheral area with limited activity in the central region. Meanwhile, their innate exploratory drive motivates them to venture into the central area, enabling the assessment of anxiety‑related behaviours induced by this conflict.

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• 6 months ago - submitted by Qifei Cong

The open‑field test system for neurobehavioural analysis is designed to observe and investigate neuropsychiatric changes in experimental animals, as well as their diverse behaviours upon entry into an open environment. Animals typically exhibit fear of novel open spaces, leading them to move predominantly in the peripheral area with limited activity in the central region. Meanwhile, their innate exploratory drive motivates them to venture into the central area, enabling the assessment of anxiety‑related behaviours induced by this conflict. brochure pdf needed

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• 6 months ago - submitted by Qifei Cong

Software code and pipelines for the study of pan-cancer myeloid immunosenescence. Analytical framework integrates bulk RNA-seq (GTEx/TCGA) and multi-cohort single-cell RNA sequencing (scRNA-seq) data to construct high-resolution myeloid atlases, cellular communication networks, and clinical prognostic signatures.

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• 6 months ago - submitted by han Jiang