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Pipetting Robot enables automated pipetting with mounted any of INTEGRA’s 25 multichannel electronic pipettes or D-ONE single channel pipetting modules onto the ASSIST PLUS pipette holder. Provides different pipetting programs.
Facility that generates, analyzes, and interprets high-throughput genomic data to understand the genetic basis of disease. Genomics Platform has played leadership role in the design, data generation, and methods development in support of major genomic resource projects.Through the Broad Clinical Labs (BCL), formerly known as the Clinical Research Sequencing Platform (CRSP), it supports clinical trials, diagnostic testing, and major initiatives, including COVID-19 testing. Offers services including Nucleic Acid Extractions, Single Cell Sequencing (using 10x Genomics products), and GWAS Arrays.
Core research service unit at the Charité – Universitätsmedizin Berlin specializing in laboratory animal husbandry, breeding, and experimental usage for biomedical research. Provides infrastructure for animal-based studies, ensures compliance with animal welfare regulations (e.g., training, veterinary oversight), and supports the creation of genetically modified models.
Core offers broad spectrum of behavioral tools to characterize novel animal models, including assays of cognition, exploratory behavior, social interaction, motivation, anxiety‑related behavior, and motor performance. In addition to classical tests such as the Barnes maze, elevated plus maze and open field, the facility develops and implements novel, high‑throughput and ethologically relevant approaches to monitor rodent behavior with particular emphasis on social interactions.
Redox and Bioenergetics core provides instrumentation, cutting-edge techniques, and expertise dedicated to investigating cancer cell metabolism and redox signaling, and to design custom probes for reactive oxygen species (ROS) for MCWCC members.
Web service provides functional annotation of cell types within the lung and combines functional and single cell data for a rigorous catalogue of cell lineages.
Software Python package to study microbial communities using metabolic modeling. Metagenome-scale modeling to infer metabolic interactions in the gut microbiota.
Software tool to analyse interactions in microbial communities. Species metabolic interaction analysis (SMETANA) of microbial communities.
Software extended tools for correlation analysis and visualization.
120 kV Transmission Electron Microscope (TEM) designed for high-contrast, high-resolution imaging in biological and materials science, often operated in, lighted rooms. It features a proprietary dual-mode objective lens for switching between wide-field and high-resolution views, along with automated, user-friendly software for navigation and image acquisition.
Imaging system used in laboratories for chemiluminescence and fluorescence imaging, specifically for detecting and analyzing protein bands (Western blot), DNA/RNA gels, and RGB fluorescence. It features a cooled CCD camera for detecting low-abundance samples.
Upright microscope designed for histology and pathology. With motorized z-focus, motorized and coded 7x nosepiece, fully automated transmitted light axis, and fully automated 5x or 8x fluorescence axis, the automated Leica DM6000 B research microscope provides all transmitted light contrast methods including the world’s first fully automated Differential Interference Contrast (DIC).
Software R package for assessment of PCR artifacts in RNA-Seq data. Used for duplication rate quality control for RNA-Seq datasets.
Software open-source Python library providing graphical user interface for visualization and manual curation of large-scale electrophysiological data. It is optimized for high-density multielectrode arrays containing hundreds to thousands of recording sites.
Specialized, compact, all-in-one fiber photometry system designed to monitor neural activity or neurotransmitter levels in freely moving animals. By combining multiple built-in LEDs (405-440 nm, 460-490 nm, etc.) and photodetectors, it enables simultaneous, multi-wavelength measurement of calcium indicators (e.g., GCaMP) and red fluorophores alongside isosbestic controls to correct for movement artifacts.
Specialized, high-performance power supplies and controllers designed for neuroscience research, specifically to drive Connectorized LEDs and fiber-coupled light sources. They offer 1, 2, or 4 independent channels for controlling light intensity, modulation (CW, TTL, analog), and complex, software-defined, or automated pulse sequences required for optogenetics and photometry experiments.
FPGA-based data acquisition unit designed for real-time monitoring of neural activity in behaving animals. It synchronizes excitation light sources (LED drivers) with detection (photodetectors) to record fluorescence signals, typically using lock-in amplification to filter noise and separate multiple wavelengths (e.g., ).
Core provides immunopathological services from sample embedding and staining to microscopic evaluation. Full service for histopathology includes tissue embedding, staining of tissue sections and microscopic analysis: preparation of paraffin blocks,cutting of cryo and paraffin sections,histochemistry,immunohistochemistry/-fluorescence/multiplexing, in-situ hybridization,Scoring/quantification,storage.
Software tool for calling copy number variants (CNVs) from human DNA sequencing data. It can work either with germline data, or paired tumor/normal samples. Its primary input is aligned reads (in .bam format), and its primary output is a report (in a .vcf file) giving the copy number status of the genome.
Core provides comprehensive proteomic analyses using LC-MS platforms, supporting post-translational modifications, protein-protein interactions, spatial proteomics, and single-cell workflows with bioinformatics.