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The Mitochondrial Function and In Vivo Imaging (MF-II) Core provides specialized expertise, advanced instrumentation, and comprehensive services for assessing mitochondrial function, metabolism, cardiopulmonary physiology, and in vivo structure and function. The Core supports cardiovascular, pulmonary, and vascular research through high-resolution metabolic and mitochondrial analyses, noninvasive imaging, hemodynamic assessment, and established preclinical disease models. The MF-II Core works collaboratively with investigators to provide experimental design consultation, technical expertise, data acquisition, and analysis to generate high-quality, reproducible data.

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• 2 months ago - submitted by Peng Zhang

The Mitochondrial Function and In Vivo Imaging (MF-II) Core provides specialized expertise, advanced instrumentation, and comprehensive services for assessing mitochondrial function, metabolism, cardiopulmonary physiology, and in vivo structure and function. The Core supports cardiovascular, pulmonary, and vascular research through high-resolution metabolic and mitochondrial analyses, noninvasive imaging, hemodynamic assessment, and established preclinical disease models. The MF-II Core works collaboratively with investigators to provide experimental design consultation, technical expertise, data acquisition, and analysis to generate high-quality, reproducible data.

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• 2 months ago - submitted by Peng Zhang

This is a test - DELETE

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• NIF
• 2 months ago - submitted by Matt Travers

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• 3 months ago - submitted by Muna Mohammed

Labeled calcium indicators are molecules that exhibit an increase in fluorescence upon binding Ca2+. They have uses in many calcium signaling investigations, including measuring intracellular Ca2+, following Ca2+ influx and release, and multiphoton excitation imaging of Ca2+ in living tissues. Cells may be loaded with the AM ester forms of these calcium indicators by adding the dissolved indicator directly to dishes containing cultured cells. The fluorescence signal from these cells is generally measured using fluorescence microscopy, fluorescence microplate assays, or flow cytometry.

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• 3 months ago - submitted by Muna Mohammed

CellTrace™ Violet Cell Proliferation Kit is used for in vitro and in vivo labeling of cells to trace multiple generations using dye dilution by flow cytometry.

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• 3 months ago - submitted by Muna Mohammed

A verification and grounding layer for AI-driven genome writing: checks proposed genomic edits against validated tools and calibrated models rather than relying on language model outputs alone.

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• 3 months ago - submitted by Anees Ahmed Mahaboob Ali

The cellenONE® is an open platform for single-cell isolation and nanoliter-scale dispensing. It leverages the sciDROP PICO technology combined with advanced vision processing to enable real-time, highly precise single-cell isolation and dispensing. Gentle acoustic droplet generation ensures excellent cell viability, making it suitable for cell line development and single-cell sequencing applications. insuffcient information letter

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• 3 months ago - submitted by Yujing Zhong

The Zeiss Axio Incubation Microscope is an inverted fluorescence incubation microscope equipped with CO2 and temperature control designed for live cell imaging, advanced biological research and automated fluorescence imaging. This microscope can perform varied transmitted light and multi-channel fluorescence light imaging including z-stack, tiling, time series and multi-area time series measurement and is fully equipped with color and monochrome imaging modes. The system’s Apotome is able to maintain focus over long periods of time during time series imaging. Objectives include long working distance/multi-immersion/oil immersion ranging from 5x to 100x. Compatible sample carriers include slides, petri dishes and multi-well plates.

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• 3 months ago - submitted by Texas State CRO

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• 3 months ago - by Anonymous

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• 3 months ago - submitted by Texas State CRO

The Leica EM UC7 Ultramicrotome equipped with the Leica EM FC7 provides advanced sectioning capabilities for both room temperature and cryogenic applications. The system enables preparation of ultra-thin and semi-thin sections suitable for electron microscopy, light microscopy, and atomic force microscopy, ensuring high precision and reproducibility across diverse research workflows.

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• 3 months ago - submitted by Texas State CRO

The Leica RM2125 RTS is a high-precision manual rotary microtome designed for reliable and efficient sectioning of paraffin-embedded tissue in clinical and research laboratories. Built for durability and ease of use, it delivers smooth operation, precise section control, and enhanced sample protection—making it ideal for routine histology workflows.

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• 3 months ago - submitted by Texas State CRO

The DektakXT® stylus surface profiler is an advanced thin and thick film step height measurement tool. In addition to profiling surface topography and waviness, the DektakXT system measures roughness in the nanometer range. It provides a step-height repeatability of 5Å.

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• 3 months ago - submitted by Texas State CRO

The Axio Observer 7 is an inverted microscope optimized for life science research. The objectives offered are the 5x and 20x air objective, 40x water immersion objective, and the 63x and 100x oil immersion objective. It is suitable for a wide range of applications, from routine brightfield imaging to advanced fluorescence and live-cell experiments.

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• 3 months ago - submitted by Texas State CRO

The FV3000 is a laser scanning confocal microscope system that captures high-resolution, high-contrast images by scanning samples point by point, enabling precise 3D fluorescence imaging. The system supports inverted and upright configurations and accommodates various objectives with magnifications ranging from 1.25× to 100×, including oil, silicone, and dry lenses, which allows imaging of both macro and micro-scale samples. It is equipped with multiple laser lines for excitation, including 405 nm, 488 nm, 561 nm, and 640 nm, as well as additional lines in some configurations (445 nm, 514 nm, 594 nm, 630 nm), enabling the use of several fluorophores simultaneously. On the detection side, the microscope uses high-sensitivity photomultiplier tube detectors, including GaAsP PMTs and multi-alkali PMTs.

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• 3 months ago - submitted by Texas State CRO

The R package multiMiR, with web server at http://multimir.org, is a comprehensive collection of predicted and validated miRNA-target interactions and their associations with diseases and drugs.

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• 3 months ago - submitted by Kemal Ugur Tufekci

Centralized molecular and analytical core that provides full service genomic library preparation, high-throughput DNA/RNA extractions, small molecule analysis, and routine isolation and storage of microbial strains. Specializes in environmental samples and offer low-cost fees for training and walk-in instrument use. Functions as a bio-repository of experimental arthropod models including Drosophila and other endemic insects.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core offers standard and specialised histology services including tissue processing (murine, human and Drosophila tissue), processing of cellular material (cells, crypt cultures, organoids and spheroids), microtomy, cryo-microtomy, haematoxylin and eosin and specialised tissue stains along with automated immunohistochemical/ immunofluorescence/ in situ hybridisation analysis for specific labelling of individual tissue constituents.

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• 4 months ago - by Anonymous

A single cell map uses single cell transcriptomics to map hormone production and action across 47 disease-free human tissues at cellular resolution.

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• dkNET
• 4 months ago - submitted by Ko-Wei Lin