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Biomarkers Core offers high quality analysis of biological samples to support pediatric research. Provides equipment and technical expertise to assay samples using methods that combine the features of gas-liquid chromatography and mass spectrometry.
Committee to foster strategic thinking about how to more rigorously manage the transition from analog to digital in higher education to ensure the programmatic, concerted, and efficient development of large-scale projects that, if built as coherent elements of an emerging digital environment, will significantly enhance scholarly productivity and enrich teaching. The Committee will produce a blueprint for this new environment that is cost effective and sustainable by focusing on the following activities: research and analysis of key large projects and the technology requisite for their correlation; business plans necessary for a coherent, sustainable digital ecology of enormous scale in service to education and the public good; and return on investment, that is, the benefits and transformational aspects of such an undertaking.
Software tool to analyze Flow or mass cytometry data using a Self-Organizing Map. Used to obtain an overview of how all markers are behaving on all cells, and to detect subsets that might be missed otherwise.
Workflow for preprocessing cfDNA samples. Unified, standardized, and ready-to-use workflow for processing whole genome sequencing cfDNA samples from liquid biopsies. Includes steps for pre-processing raw cfDNA samples, quality control and reporting. Additionally, several optional utility functions like GC bias correction and estimation of copy number state are included. Provides specialized methods for extracting coverage derived signals and visualizations comparing cases and controls.
The UK''s leading MS charity that provides information and support, funding research and fighting for change. We''re a democratic organization: one member, one vote. We fund research, give grants, campaign for change, provide information and support, invest in MS specialists and lend a listening ear to those who need it. The UK''s biggest MS charity. * 38,000 members have a say in how we''re run. * 9000 volunteers give a million hours every year. * 550 staff work in all four nations of the UK. * Over 300 branches support people with MS locally. * One aim: to beat MS. Our national offices in England, Scotland, Wales and Northern Ireland and our network of 300 branches support people affected by MS locally.
Core is a nonprofit research institute that applies bioinformatics, software engineering and next-generation sequencing. Equipped with Illumina and PacBio instrumentation, our sequencing capabilities include genome, transcriptome, methylome, ChIP, small RNA, and exome sequencing, with corresponding analytical capabilities. NCGR provides researchers with experimental design assistance, custom data analysis, and data visualization.
Core provides expertise and resources for large scale biology. Helps to set up, run, gather data and perform analysis in drug discovery research, biochemistry, cell and organismal biology, functional genomic screening, and synthetic genetic. Works with proteins, nucleic acids, small model organisms, and microbial strains. Provides tissue culture,produces and uses lentivirus particles, screens compound libraries, does experiments for investigators,generates preliminary data to figure out if idea is workable, discusses project development. Services include Macromolecular binding, biochemical, and cell-based assays,High content screening with widefield or confocal optics,Nanoliter liquid handling up to 1536-well density,Whole-plate kinetic assays (ion currents, GPCR signaling),Compound library screening,CRISPR/Cas9 screening (multiplexed libraries),Analysis of large data sets,Fluorescence Thermal Shift assay (measures protein melting),Complex liquid handling work flows.
A repository of biological samples and data from people with multiple sclerosis, selected other demyelinating diseases, and unaffected controls. The repository not only provides much-needed samples and data to researchers studying MS and other diseases, but also aggregates the results from all of these studies so that they can be analyzed collectively, leading to new findings and breakthroughs. The repository collects blood, DNA, and imaging once per year. The repository currently includes samples and data from over 2,700 subjects with Multiple Sclerosis, Neuromyelitis Optica, Acute Disseminated Encephalomyelitis, Transverse Myelitis, Optic Neuritis, and Clinically Isolated Syndromes, as well as controls. Blood samples are provided as aliquots as serum, plasma, DNA, RNA, and lymphocytes and each sample is accompanied by more than 40 pages of clinical and epidemiological data contributed by the subject and the enrolling neurologist.
Software tool for assembling transcripts from RNA-Seq data. Explores surprising computational parallels between assembly of transcriptomes and single cell genomes. Suitable for all kind of organisms. Part of SPAdes package since version 3.9.
National MagLab headquartered in Florida State University in Tallahassee. The lab also includes sites at Los Alamos National Laboratory in New Mexico and University of Florida in Gainesville. It serves as user facility. Major center for condensed matter physics and materials science, often collaborating with university researchers for scientific discovery.
Donor Alliance is one of 58 not-for-profit organ recovery organizations federally designated by the U.S. Department of Health & Human Services to facilitate the donation and recovery of organs for people needing transplants. Additionally, Donor Alliance is a recognized leader in facilitating the donation and recovery of transplantable tissues in Colorado and most of Wyoming. Our goal is to save the lives of people in need. To achieve this, Donor Alliance employs effective family approach and recovery programs in more than 100 hospitals in Colorado and Wyoming. Additionally, Donor Alliance dedicates time, funding and effort toward increasing the number of registered organ and tissue donors through active public awareness and educational programs and grassroots public relations campaigns.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 18th, 2023. Software that uses long reads to close gaps in the assemblies., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Software modular pipeline for constructing pathway/genome databases from environmental sequence information. Used for predicting metabolic functions of given DNA sequences. Produces structured data products as pathway-genome databases with human-readable and machine-interpretable representations. MetaPathways v3.5 is updated algorithm for sequence feature prediction, annotation, metabolic inference, and coverage metrics including genome resolved metagenomes.
A python toolkit providing best-practice pipelines for fully automated high throughput sequencing analysis.
A cross-platform class library for development of high-performance life science computer simulations. It supports modelling for biomedical cybernetics and systems biology with Object Pascal. It contains a set of Pascal units for rapid programming of high-performance computer simulations called the Brick collection.
Integrates technology in single-particle cryogenic electron microscopy. Thermo Scientific Talos L120C Transmission Electron Microscope is available for visualizing nanoparticles, negatively stained proteins or conventional biological samples. It can be operated at 80kV or 120kV. Thermo Scientific Glacios 200 kV cryogenic TEM is equipped with both Ceta-16M camera and TFS Falcon 4 direct electron detector, in addition to Selectris Energy Filter. This system is able to generate images for atomic resolution structures for single particle analysis projects. Glacios also includes software for micro-Electron Diffraction data set collection. Available services include Training and access to the Mark IV Vitrobot plunge freezer,Training and access to the Talos L120C TEM system, Training and access to the Glacios 200 kV cryogenic TEM system, Assisted TEM analysis by CASB personnel.
THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 7, 2022. Functional Genomics Data Society - FGED Society, founded in 1999 as the MGED Society, advocates for open access to genomic data sets and works towards providing concrete solutions to achieve this. Our goal is to assure that investment in functional genomics data generates the maximum public benefit. Our work on defining minimum information specifications for reporting data in functional genomics papers have already enabled large data sets to be used and reused to their greater potential in biological and medical research. We work with other organizations to develop standards for biological research data quality, annotation and exchange. We facilitate the creation and use of software tools that build on these standards and allow researchers to annotate and share their data easily. We promote scientific discovery that is driven by genome wide and other biological research data integration and meta-analysis.
anti-EGF Receptor (3F12) Mouse mAb is antibody from Zen bioscience used only in research.
Core provides electron microscopy services, instrumentation and training. Services include consultation and experimental design for wide variety of biological samples for both Transmission Electron Microscopy and Scanning Electron Microscopy.
A central tissue repository at Moffitt specializing in protocol-driven human tissue collection, storage, processing and dissemination. Tissue Core provides investigators with access to high quality, well-annotated human specimens obtained from representative of the patient populations. The advent of powerful molecular technologies has opened the door to developing more effective treatments of patients with cancer. Access to high quality specimens with associated clinical, treatment, recurrence outcome data will be critical to developing and validating the tests needed for diagnosis and prediction of response to therapy. Since its commencement in 1993, the Tissue Core has collected more than 8,000 cases of human liquid cancers and solid primary and metastatic tumors both malignant and benign with adjacent normal, from variety of sites and diagnoses. Collected samples are mostly remnant tissues obtained from patients undergoing therapeutic surgical procedures at the Center. The core also ensures tissue release compliance with USF-IRB and Privacy Board recommendations. * Protocol driven sample collection, processing and distribution * Collection of sample and patient demographic information. * Nucleic acid extractions from tissue sections, FNA, core biopsies blood and bone marrow. * Histology services: H&E slides, staining, sectioning, paraffin blocks, OCT blocks, sample microdissection * WBC, plasma and serum isolation. * Project development and support: Facility staff provides advice and guidance to researchers.