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System equipped with DNP (Dynamic Nuclear Polarization) used primarily to dramatically boost the sensitivity of nuclear magnetic resonance (NMR) spectroscopy.It allows researchers to study complex molecular structures, materials, and biological systems that are normally difficult or impossible to observe. Console: Avance III HD; Magnet: Ascend; Field Strength:600 MHz Wide-bore; Software: TopSpin 3.8 on Alma 9.4; Probe: 3.2mm HCN LTMAS for DNP; 3.2mm HX LTMAS for DNP; 1.3mm HCN very-fast MAS.
Highly advanced system used by researchers in chemistry, biology, and materials science to determine the molecular structure, dynamics, and interactions of chemical compounds and biomolecules. Console: Avance III HD; Magnet: Ascend; Field Strength: 600 MHz, Software: TopSpin 3.7 on Windows 10; Probe: 5mm Broadband Observe (BBFO) "Smart" solution iProbe with Z-Gradients.
High-field, ultra-sensitive system used by researchers for deep structural, dynamic, and metabolic analyses of complex molecules. Console: Avance III HD; Magnet: Aeon; Field Strength: 800 MHz Wide-bore; Software: TopSpin 3.8 on Alma 9.4; Probe: 3.2mm Efree HCN MAS; 3.2mm HXY MAS; 1.9mm HCN MAS; 1.3mm HCN MAS; 0.7mm HCND ultra-fast MAS.
Spectrometer represents the pinnacle of commercial nuclear magnetic resonance technology. Operating at 28.2 Tesla, this ultra-high-field system is primarily used for advanced structural biology, pharmaceutical research, and materials science. Delivers the highest commercially available spectral resolution, crucial for investigating complex protein dynamics, functional molecular disorders, and viral structures. Console:Avance Neo; Magnet:Gateway; Field Strength: 1.2 GHz; Software:TopSpin 4.4.1 on CentOS 7; Probes:3mm TCI cryoprobe; 3mm BBI room-temperature; 3.2mm HX low-gamma MAS; 1.9mm HX high-gamma MAS; 1.3mm HCN fast MAS; 0.7mm HCN ultra-fast MAS; Chilled SampleCase (up to 24 samples); Automated Tuning and Matching (ATM); Nitrogen Liquefier.
Spectrometer used for advanced chemical, biological, and materials research. It allows scientists to determine the atomic-level structure, dynamics, and interactions of molecules. Console: Avance Neo; Magnet: Ascend; Field Strength: 800 MHz; software:TopSpin 4.4.1 on CentOS 7; Probe: 5mm QXI-F solution; 5mm TXI solution; 4.0mm gradient hr-MAS; 3.2mm Efree; 2.5mm Tri-gamma MAS; 1.9mm MAS; 1.3mm MAS; 0.7mm ultra-fast MAS.
High-end analytical system used by researchers in chemistry, biology, and materials science. It determines the molecular structure, dynamics, and interactions of organic compounds, proteins, and polymers. Console:Avance III HD; Magnet: Ascend; Field Strength: 700 MHz; Software:TopSpin 3.8 on Alma 9.4; Probe: 5mm Triple-resonance Observe (TXO) cryoprobe with Z-Gradients.
High-resolution Nuclear Magnetic Resonance (NMR) spectrometer. Operating at 14.1 Tesla, it features an ultrashielded magnet for superior stray-field reduction and spatial efficiency. It is widely used for advanced structural analysis of small molecules, proteins, and macromolecules. Console: Avance III HD; Magnet: Ultrashield; Field Strength: 600 MHz; Software:TopSpin 3.8 on Alma 9.4; Probes:5mm Triple-resonance Inverse (TXI) cryoprobe with Z-Gradients.
High-field system powered by an 18.8 Tesla magnet. It is the premier tool for structural biology, metabolomics, and advanced materials research. Console: Avance III HD; Software:TopSpin 3.8 on Alma 9.4; Probe: 5mm Quadruple-resonance Inverse (QCI-P) cryoprobe with Z-Gradients.
Core staff provide expertise and technical support for a wide range of microbiome-focused research. Services and technologies, include initial project consultation, experimental design, sample collection and processing, data analysis and interpretation, grant applications.
Database for residue-level membrane protein-lipid contact annotations derived from experimentally determined Protein Data Bank structures. Includes automated Python pipeline for identifying lipid-containing PDB structures, calculating all-atom heavy-atom residue-lipid contacts using a 4.0 Angstrom distance cutoff, generating cluster-aware train, validation, and test splits, and producing documented dataset files for machine learning and structural bioinformatics. The dataset is deposited on Zenodo under CC0, while the code is released on GitHub under the MIT license. Contains large-scale experimentally-validated dataset of residue-level protein-lipid contacts from membrane protein structures.
Programmable, automated laboratory instrument used for slide based FISH (Fluorescence In Situ Hybridization) and ISH procedures. It is specialized, microprocessor controlled hot plate designed specifically for the denaturation and hybridization of DNA on glass microscope slides.
130-watt programmable sonicator manufactured by Sonics & Materials, Inc. It is commonly used in laboratory settings for processing small volumes of liquid from 150 microliters to 150 milliliters.
Ultra-high-resolution Field Emission Scanning Electron Microscope (FE-SEM). It is used to examine the micro and nano-scale surface structures of materials and is widely utilized in scientific research, electronics, and materials science.
Compact, low-pressure benchtop plasma system used primarily in laboratories and small-scale production for ultra-fine surface cleaning, activation, etching, and coating. It utilizes cold gas plasma to alter material surfaces without damaging the bulk part.
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Core provides comprehensive infrastructure and expertise to support structural biology research. Instrumentation includes Titan Krios, Talos Arctica, and Helios Hydra Bio, alongside dedicated sample preparation equipment. Offers services, consultation, and user training covering grid preparation and screening, automated data collection for single particle analysis (SPA) and cryo-electron tomography (cryo-ET), focused ion beam scanning electron microscopy (FIB-SEM), microcrystal electron diffraction (MicroED), and data processing.
HIPAA-compliant digital platform developed by the Sylvester Comprehensive Cancer Center at the University of Miami. It is used to manage clinical trials, monitor patient symptoms at home, and deliver personalized lifestyle medicine interventions. Used to conduct studies with improved protocol adherence and data collection practices, as well as participant outreach and communication. MWR enables real time, bidirectional calling and messaging, behavioral intervention delivery, remote monitoring, and electronic patient reported outcome (ePROs) data collection.
Software R package for constructing networks of samples (e.g., patients) for each available data type and then efficiently fuses these into one network that represents the full spectrum of underlying data. Used to taking multiple views of a network and merging them into a combined view.
Confocal laser scanning microscope primarily used in biological and medical research. It is designed to capture extremely detailed, 3D and 4D images of living cells, tissues, and organisms by using advanced laser technology to scan samples layer by layer.