SciCrunch

Colorado State University Flow cytometry, cell sorting, and single cell analysis Core Facility

Provides access to flow cytometry and cell sorting instrumentation, services, and expertise for all researchers at Colorado State University. FCF includes spectral flow cytometers Cytek Aurora which enables users to perform more than 25 markers in a sample. FCF also has 10X Genomics chromium controller used to barcode single cells to perform single cell sequencing. Offers data analysis of these complex flow cytmetry and single cell sequencing samples using R programming or bash shell based pipelines.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Structural Biology Shared Resource CryoEM Core Facility

Provides equipment, expert technical assistance and image analysis expertise to enable all aspects of macromolecular structure determination by single particle cryo-electron microscopy.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Structural Biology Shared Resource X Ray Crystallography Core Facility

Core performs all aspects of structure determination of large biomolecules such as proteins and nucleic acids including macromolecular crystallization, crystal screening, molecular structure and model building.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Structural Biology Shared Resource NMR Core Facility

Core enables study of biomolecular structure, dynamics and interactions in solution at atomic level. Provides NMR spectrometers from 600 MHz to 900 MHz equipped for biomolecular NMR studies. Equipment include 900 MHz Bruker Avance Neo with Oxford 21 T magnet - TCI Cryoprobe 600 MHz Bruker Avance Neo with Bruker Sample Jet (2024) - TCI Cryoprobe 600 MHz Varian Inova with HCN cryoprobe.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Small Animal Image Guided Radiation Therapy Core Facility

Core specializes in targeted irradiation of small animals for use in preclinical trials of radiation therapy. Through use of XRAD-SmART Irradiator, core can use x-ray fluoroscopy and on board CBCT to accurately irradiate small lesion areas while protecting normal tissue. Provides experiment design, data analysis, and dosimetry calculations, as well as longitudinal acquisition of CBCT for temporal assessment of tumor growth kinetics.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Pathology Shared Resource Molecular Pathology Core Facility

Molecular Pathology Section offers clinical grade sample processing and molecular testing for research cases.All services are performed in CLIA certified environment and all molecular assays are accompanied by full data analysis including bioinformatics analysis for NGS data.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Pathology Shared Resource Research Histology Core Facility

Research Histology Section provides range of standardized paraffin histology procedures that can be tailored to specific research needs.Services include tissue grossing/cassetting, paraffin processing, sectioning, routine and special stains. We specialize in immunohistochemistry and antibody optimization procedures.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Organoid and Tissue Modeling Shared Resource Core Facility

Core facilitates access, generation, and usage of novel in vitro mouse and human organoid systems to promote innovative basic and translational research and disease modeling. Provides expertise in genome editing technologies for targeted knock outs, point mutations, and reporter generation in organoid systems. Provides many specialized medias and reagents to support most common organoid culture systems.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Population Health Shared Resource Core Facility

Core supports access to and expertise in data management, analyses, and mapping and data visualization of population based databases. These databases are ideal for studies requiring access to large samples of patients and/or providers; examination of trends in treatment, screening, or other healthcare services; impact of policy changes or recommendations on healthcare services; investigating dissemination of evidence based technologies and interventions; disparities of treatment or other health care services between groups; geographic distributions of cancer patients and relationships with other geospatial data.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Pathology Shared Resource Cytogenetics Core Facility

Core, in collaboration with Colorado Genetics Lab, provides cytogenetic and cytogenomic research services. Services include tissue culture, chromosome analysis, fluorescence in situ hybridization (FISH), and chromosomal microarray. Offers design and development of customized FISH probes.Available for consultation on study design and data analysis.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center PreClinical Human Immune System Mice Shared Resource Core Facility

Core provides Human Immune System as preclinical in vivo model to study human immune system in experimental tractable animal model e.g. immune response to human tumors that readily grow in HIS-mice. Offers immune expertise, experimental procedures and data analysis of immune based assays, such as flow cytometry.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Pathology Shared Resource Biorepository Core Facility

Biorepository Section provides services to support biobanking, clinical trials, and research studies. Provides access to patient specimens collected from clinical and research procedures that are handled, processed, analyzed, and interpreted in uniform manner. Services include, collection, processing, storage, clinicopathological annotation, and distribution of biospecimens.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Mass Spectrometry Shared Resource Core Facility

Provides investigators with capabilities to identify, characterize, and quantify biomolecules present in tissues, cells, and biological fluids. Facility houses both Proteomics and Metabolomics Cores, and aims to assist members with solving difficult or previously intractable problems in biomedical research. Methods for biomolecule isolation, separation, quantification, identification and bioinformatics analysis, together with expert guidance in study design, are integrated into expertise offered by the Facility.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Functional Genomics Core Facility

Core facilitates access to tools including shRNA, ORF, CRISPR to investigate gene function on genome wide scale. Provides protocols and expertise for use of these genomics tools. Serves as forum for scientific exchange and discussion in the field of functional genomics.Sign in to iLab using University of Colorado credentials.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Drug Discovery and Development Shared Resource Core Facility

Provides expertise and infrastructure to facilitate drug discovery at different stages of development pipeline, including assay development and validation, high throughput screening and image based high content screening discovery, validation and optimization, and in vitro and in vivo pharmacology including pharmacokinetics and pharmacodynamics as well as toxicology.Sign in to iLab using University of Colorado credentials.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Human Immune Monitoring Shared Resource Core Facility

Facilitates clinical and translational studies by dissecting immune based mechanisms with diagnostic and therapeutic applications. Offers assays including immunophenotyping and functional characterization, multicolor fluorescence tissue imaging, multiplex cytokine analysis, and cellular assays.Sign in to iLab using University of Colorado credentials.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Genomics Shared Resource Core Facility

GSR provides genome-wide analyses of DNA sequence, transcriptomes, epigenetics and cytogenomics using next generation sequencing (NGS) and gene microarrays; and single cell genomic and transcriptomic analyses including single cell immune profiling and spatial gene expression.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Bioinformatics Core Facility

Cancer focused bioinformatics group that assists in all needs related to omics and big data. We assist our collaborators with experimental design, data processing, interpretation, generating publication-quality figures, and preparing manuscripts and grants.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Cell Technologies Shared Resource Core Facility

Supports basic and translational research projects in biomedical research. CTSR produces hybridomas/monoclonal antibodies to enhance basic research and preclinal studies and makes recombinant proteins for mechanistic and structural studies on proteins.Provides multiple platforms and analytic modules for real time live-cell imaging of cultured cells and organoids to enhance analysis of cancer cell biology. In addition, we maintain a collection of authenticated human cell lines for use in biomedical research. Sign in to iLab using University of Colorado credentials.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

University of Colorado Anschutz Medical Campus Cancer Center Biostatistics Core Facility

Biostatistics provides quantitative support for planning, design, analysis, and presentation of basic science, clinical, and epidemiological investigations. We are dedicated to delivering high quality, methodically developed results to improve patient outcomes and clinical care.

Resource
SciCrunch
4 years ago - submitted by Edyta Vieth

Search Again