Curator Dashboard

Cre expressing mice under the control of promoters with a design focus on the brain. Each promoter is derived from human sequence, but the resulting expression is assessed in the mouse for the activation of a LacZ reporter gene by the Cre activity. Promoters tested as large MaxiPromoters (BACs inserted into the mouse genome) and MiniPromoters (plasmid-based sequences inserted either into the mouse genome or introduced within AAV viruses). The Cre-related project continues from the Pleiades Promoter Project. Here is the list of genes for which icre/ERT2 mice are currently in development: AGTR1, CARTPT, CLDN5, CLVS2, CRH, GABRA6, HTR1A, HTR1B, KCNA4, KDM5C, MKI67, NEUROD6, NKX6-1, NOV, NPY2R, NR2E1, OLIG2, POU4F2, SLITRK6, SOX1, SOX3, SOX9,, SPRY1, VSX2

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• SciCrunch
• 16 years ago - by Anonymous

Software package for low-level analyses of single-cell RNA-seq data. Used for quality control, data exploration and normalization, cell cycle phase assignment, identification of highly variable and correlated genes, clustering into subpopulations and marker gene detection.

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• SciCrunch
• 8 years ago - submitted by Edyta Vieth

Test project for NITRC development.

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• NIF
• 2 years ago - by Anonymous

International registry that consolidates information from individuals with Phelan-McDermid Syndrome into a single database, which will be utilized by researchers to understand Phelan-McDermid Syndrome better. In order to accelerate translational efforts (moving from basic laboratory research to meaningful health outcomes, such as therapies and treatments) related to Phelan-McDermid Syndrome, PMSF is funding the Phelan-McDermid Syndrome International Registry. The Registry is important for characterizing and understanding the syndrome better. Not only will the Registry provide valuable information for families and doctors to make the best care decisions possible, it will be important to help researchers decide what are the most important challenges to address. The Registry will also help scientists find out if there are any PMS patients who might be a good match for their research studies. Collecting information from PMS patients is very important, but protecting the privacy of people affected by PMS is also extremely important. In order to protect your privacy, Patient Crossroads (the company that designed the registry software) has designed many safeguards. Your child''s information will be de-identified so no one who looks at the data can identify you or your child. Your child''s information will be assigned a code. If a researcher is interested in learning more about your child, the researcher will ask the Patient Crossroads/PMSIR genetic counselor to contact you. A scientist will not be able to receive any identifying information about your child unless you give explicit consent for your child''s identity to be released to that researcher. BE PART OF OUR INTERNATIONAL REGISTRY The Registry will provide valuable information for families and doctors to make the best care decisions possible, and it will help researchers decide what are the most important challenges to address in PMS. Establishing the registry addresses two important scientific needs. First, scientists studying PMS need accurate, firsthand information to understand how PMS affects people. Second, scientists who are ready to start studies, such as those that test new treatments, will be able to access The Registry to identify people that may be eligible to participate in studies. In either case, your privacy is assured while the cause of research is advanced. While raw data about PMS will be available to scientists, they won''t have access to any identifying information about your child unless you agree to have your child''s identity released.

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• SciCrunch
• 16 years ago - by Anonymous

Cellular Taxonomy of Mouse Visual Cortex by analyzing gene expression patterns at single cell level. Construction of cellular taxonomy of one cortical region, primary visual cortex, in adult mice done on basis of single cell RNA sequencing.

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• RRID-Legacy
• 8 years ago - submitted by Victoria Perreau

Core works with researchers, clinicians and other research technology platforms to establish the best possible approach for any genomics experiment. Offers expertise on variety of off-the-shelf sequencing products and implementation or customisation of new protocols to meet demands of cancer research.

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• RRID
• 2 years ago - submitted by Tim Semple

Nevada Donor Network (NDN) is a federally designated, not-for-profit organ, tissue, and eye procurement organization. NDN is responsible for the coordination, recovery, and distribution of donated human organs and tissues for transplantation and medical research throughout the Las Vegas area. In addition, NDN participates in national organ and tissue sharing in an effort to meet the ever-growing needs of patients awaiting transplantation therapy. NDN is one of the few organ procurement agencies in the country to manage the recovery of organs, tissues, and eyes in the same facility, making Nevada progressive in the field of organ and tissue procurement. NDN is certified by the Department of Health and Human Services and the Center for Medicare and Medicaid Services (CMS). The Network is accredited by the Eye Bank Association of America (EBAA), the American Society for Histocompatibility and Immunogenetics (ASHI), the Clinical Laboratory Improvement Act (CLIA), and the American Association of Tissue Banks (AATB).

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• SciCrunch
• 16 years ago - by Anonymous

Software Python tool for sleep EEG analysis. Used for Closed and Open loop in Slow Ocillations, Sleep Stimulation in Auditory or Recording in full PSG using OpenBCI Cyton.

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• SciCrunch
• 8 years ago - submitted by Frederik D. Weber

Core facility that provides expertise and instruments/equipment to promote research in nutrition and/or women’s health by leveraging resources from new and existing institutional programs and fostering collaborations across disciplines. Consists of hub laboratory suite with wet bench laboratory, body composition assessment and resting metabolic rate laboratories, computer laboratory, metabolic kitchen, and network of partnering laboratories distributed across the UI and the state of Idaho.

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• RRID
• 2 years ago - by Anonymous

Donor Network of Arizona is the federally designated, not-for-profit, organ procurement organization for the state of Arizona and a tissue and eye recovery organization. DNA serves five organ transplant centers in Arizona with the combined capacity to perform heart, lung, kidney, pancreas and liver transplants. * Our Mission: We make the most of life through the gift of organ and tissue donation. * Our Vision: We challenge ourselves and others everyday to realize Arizona''s potential to save and improve lives. DNA shares organs regionally and nationally through the United Network for Organ Sharing''s (UNOS) national network. DNA is accredited by the Association of Organ Procurement Organization, American Association of Tissue Banks and the Eye Bank Association of America.

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• SciCrunch
• 16 years ago - by Anonymous

System to extend constant distance mode mass spectrometry imaging using nanospray desorption electrospray ionization by integrating shear force probe with nano DESI probe to improve imaging capabilities. Used for imaging biological samples of complex topography in their native states. Enables ambient imaging of biological samples with high sensitivity and minimal sample pretreatment.

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• RRID-Legacy
• 8 years ago - submitted by Anh Nguyet Vu

Core offers imaging for diverse applications, including multi-color experiments, live sample imaging, protein colocalization, large sample tiling, and Z-stack 3D/4D imaging, as well as weak label detection. Provides expert guidance in microscopy and image analysis, training and support to advance research across various model organisms.

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• RRID
• 2 years ago - by Anonymous

A web-application designed for scientific exploration of metagenome sequence data collected from viral assemblages occurring within a number of different environmental contexts. The VIROME informatics pipeline focuses on the classification of predicted open-reading frames (ORFs) from viral metagenomes. The portal allows you to submit your viral metagenome to be processed through the VIROME analysis pipeline, and enable you to investigate your data via the VIROME user interface., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 13 years ago - by Anonymous

Open source pulse train generator that allows users to create and trigger software defined trains of voltage pulses with high temporal precision. Generates precisely timed pulse sequences for use in research involving electrophysiology or psychophysics.

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• RRID-Legacy
• 8 years ago - by Anonymous

Core provides nondestructive, high-resolution images of internal structure of variety of natural and engineered materials using X-ray micro-computed tomography. microCT can resolve structures on micrometer scale.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

The Lymphoma Research Foundation (LRF) is the nation''s largest non-profit organization devoted exclusively to funding innovative lymphoma research and providing people with lymphoma and healthcare professionals with up-to-date information about this type of cancer. LRF''s mission is to eradicate lymphoma and serve those touched by this disease. LRF was formed in November 2001 by the merger of the Cure for Lymphoma Foundation (CLF) and the Lymphoma Research Foundation of America (LRFA). Both organizations were founded by lymphoma advocates who sought to use their personal experiences with lymphoma to benefit others with the disease. CLF was founded in 1994 in New York City by Jerry Freundlich, a non-Hodgkin lymphoma survivor, and his wife Barbara Freundlich. LRFA was founded in 1991 by Ellen Glesby Cohen, who lost her own battle with non-Hodgkin lymphoma in August 2000. Our goal is to change the future for everyone whose life has been affected by a lymphoma diagnosis. We are dedicated to funding biomedical research focused on the origins, treatment and identification of a cure for lymphoma; to raising public awareness of the disease; and providing support and services to people with lymphoma, their families and caregivers.

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• SciCrunch
• 16 years ago - by Anonymous

Portal and database of DNA sequence, functional and epigenomic information, and clinical data from studies on type 2 diabetes and analytic tools to analyze these data. .Provides data and tools to promote understanding and treatment of type 2 diabetes and its complications. Used for identifying genetic biomarkers correlated to Type 2 diabetes and development of novel drugs for this disease.

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• Consortia-pedia, a FasterCures Project
• 13 years ago - by Anonymous

Core assists investigators to identify and quantify proteins and their modifications that are differentially expressed in cells, tissues or body fluids, to track interactions with binding partners during changes in signal transduction, and to identify proteolytic cleavage sites and map post-translational modifications by providing following proteomic services: Consultation, Sample preparation,Protein Identification,Protein Modifications, Protein Quantification, Targeted Quantification, High Resolution Mass Analysis,Training and Self-Service Equipment. Core offers workshops to use the Core’s MALDI-TOF mass spectrometer, Typhoon gel imaging scanner and 2D gel electrophoresis equipment and proteomic software.

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• RRID
• 2 years ago - by Anonymous

Epilepsy Research Ireland is a non-profit organization (Charity CHY17527), run by a group of volunteers, who are dedicated to find cure for epilepsy by raising awareness and money for research. We can say cure now with much more confidence than we could even 10 years ago because recent advances in genetics, brain imaging and drug therapy, all hold out the promise of that holy grail the cure. We can also say with confidence that you can be part of that push by participating in this new foundation since we have collaborations with doctors and scientists all over Europe, the US and Australia, all of whom share the same goal. Epilepsy research, conducted by Epilepsy Research Ireland, is essential and will deliver benefits across the board. Research planned and already underway by Epilepsy Research Ireland will help develop and improve clinical skills; it will provide a knowledge base to develop new ways to manage and treat epilepsy; it will help in the evaluation of new medical advances. Ultimately we can improve the quality of care and provide greater understanding, better and more accurate diagnosis and more tailored treatments. Ireland is uniquely well-positioned, given its relatively homogenous population to make the goal, of making real discoveries in epilepsy research that will directly improve the lives of people with epilepsy, a realistic one.

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• SciCrunch
• 16 years ago - by Anonymous

Software R package for tree ensembles such as random forests, regularized random forests and gradient boosted trees. Provides functions for extracting, measuring and pruning rules, selecting compact rule set, summarizing rules into learner, calculating frequent variable interactions, formatting rules in latex code.

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• RRID-Legacy
• 7 years ago - by Anonymous