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Peptide drug refers to a peptide having a specific therapeutic effect extracted by chemical synthesis, genetic recombination or animal or plant, and is a specific application of the peptide in the field of medicine. The biological activity of the peptide is extensive and important, and it can be widely applied to the endocrine system, the immune system, the digestive system, the cardiovascular system, the blood system, the musculoskeletal system, etc. With a team of experienced experts, advanced research equipment and proprietary methods, Creative Peptides provides a one-stop shop services for your early peptide drug discovery and accelerates your drug development process. The combination of our proprietary surface plasmon resonance (SPR) service and MHC-peptides tetramer service, diverse peptide libraries and arrays also provide an important channel for your peptide screening.

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• 4 years ago - submitted by Caroline Miller

Service uses bioinformatics methods to compress peptide information, which can integrate information of multiple peptide into one peptide. Provides collection of small peptide of specific length and different sequences, which includes permutation and combination of various amino acid sequences in short peptide of this length.Total peptide library for new drug research and development.

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• RRID
• 4 years ago - submitted by Caroline Miller

Pipetting Robot offers repeatable, traceable pipetting with connected single and multichannel electronic pipettes. Enables automation of many routine sample preparation workflows.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

System includes SQD2 as single quadrupole MS with Waters H-Class Acquity UPLC, operated as open access platform for trained users. SQ Detector2 is single quadrupole mass detector for chromatography compatible with range of chromatography platforms and ionization sources.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Exploris 240 system is hybrid quadrupole Orbitrap mass spectrometer with Waters H-Class Acquity, ZipChip, and DART front ends. Flexible platform for wide range of small molecule and intact protein analyses.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Exploris 480 system is hybrid quadrupole Orbitrap mass spectrometer with Waters M-Class Acquity. Proteomics system for hands on use by highly trained users.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core provides industry standard high throughput screening and automated microscopy capabilities to scientists performing drug discovery research. Provides access to automated infrastructure to support phenotypic and biochemical targets. Provides ready access to collections of current FDA approved drugs and clinical candidates exhibiting drug like qualities of acceptable solubility, desirable ADME/toxicology properties and adequate bioavailability. Has collections of mechanistically annotated informer sets that are pathway specific modulators for studying mechanism of action or target identification, collections of natural products and diverse sets of small molecules that can be interrogated for new target discovery. Each project is individually evaluated and team of scientists from CDDP is created to fit specific needs of project from assay design and development through primary, secondary and orthogonal screening.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

this is a test

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• 4 years ago - submitted by Anita Bandrowski

System includes Thermo Orbitrap Eclipse Tribid mass spectrometer and Waters M-Class Acquity nanoUPLC. This platform features sequential acquisition capabilities and multiple fragmentation types, enabling complex, in depth proteomic experiments.

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• SciCrunch
• 4 years ago - submitted by Allis Chien

Services include RNA quality control, amplification and labeling, array hybridization, scanning and data analysis, assisting customers in design and performance of microarray experiments, using Agilent (pre-made and custom) and Affymetrix arrays. Provides support for quantitation and quality assessment of DNA, RNA and protein on Agilent 2100 Bioanalyzer. Provides training and support for Agilent and Affymetrix Hybridization oven users. Provides support for microarray scanning and for data analysis with variety of software packages for both Agilent and Affymetrix platforms.Quantity and quality of your RNA, DNA, proteins and cells are determined with help of Agilent 2100 Bioanalyzer.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core mass spectrometry facility located in Department of Chemistry, University of Toronto, which houses several mass spectrometers. Services include:High resolution, accurate mass determinations of small molecules via EI, ESI and DART ionization;Mass determinations of intact peptides and proteins via ESI-QTOF-MS and MALDI-MS; HPLC-MS/MS analysis of protein digests via ESI-QTOF-MS; Quantitative analysis via HPLC-MS/MS using QqQ instrumentation.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Light microscopy core is open to HMS researchers, including Affiliated hospitals. Supports imaging modalities ranging from wide field, TIRF, spinning disk and single point scanning confocal, multiphoton, FLIM and supper resolution. Microscopes are embedded within Departments of Microbiology, Immunology, and Genetics, housed in five microscope rooms on five floors of NRB and HIM.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Software tool for simulating spatially inhomogenous biochemical reaction diffusion systems for modelling cell environment feedbacks. Simulation software for spatially organised biochemical systems.

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• RRID-Legacy
• 4 years ago - by Anonymous

Software pipeline for processing and analysis of large scale spatial transcriptomics data. Enables reproducible data processing from raw sequencing data to automatically generated downstream analysis reports.

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• SciCrunch
• 4 years ago - by Anonymous

Software R package to project cells into shared embedding in which cells group by cell type rather than dataset specific conditions. Harmony simultaneously accounts for multiple experimental and biological factors. Used for integration of single cell data.

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• SciCrunch
• 4 years ago - by Anonymous

Public research university in Brazil commonly called Unicamp. Recognized as one of the best universities in Latin America.

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• RRID-Legacy
• 4 years ago - submitted by Edyta Vieth

Core is specialized in stereology techniques, live cell imaging, CLSM (confocal microscopy), and STORM. Provided instruments include CONFOCAL microscopes Zeiss LSM 5 Pascal, Olympus BX51-WI,Olympus IX71 inverted microscope, Nikon Labophot-2 microscope,Nikon Optiphot 2 microscope.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core produces mice and rats for biomedical research. Provides services for customers are researchers from Unicamp and other Institutions from Brazil.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core provides access to instrumentation essential for studies of surface and interfacial properties of materials, such as ion and electron based spectroscopies, electron, optical and scanning probe microscopies. Core provides training to students and faculty on instrumentation as well as consolation of measurements needs and data interpretation, supports educational activities involving lab tours, workshops, hands on demonstrations, outreach and broader impact related activities through our open house and lunchtime seminar series.Supports collaborative research projects with outside industrial users.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides histology (including cryosectioning, IHC and IFC) digital pathology and veterinary pathology (board certified veterinary pathologist on staff) services.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth